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List of works by Toru Furukawa

A Consensus Study of the Grading and Typing of Intraductal Papillary Mucinous Neoplasms of the Pancreas

scientific article published on 01 April 2019

A GNAS mutation found in pancreatic intraductal papillary mucinous neoplasms induces drastic alterations of gene expression profiles with upregulation of mucin genes.

scientific article published on 03 February 2014

A Revised Classification System and Recommendations From the Baltimore Consensus Meeting for Neoplastic Precursor Lesions in the Pancreas

scientific article

A cDNA microarray analysis identifies 52 genes associated with cis-diamminedichloroplatinum susceptibility in head and neck squamous cell carcinoma cell lines.

scientific article

A case of solid pseudopapillary neoplasm of the pancreas presenting with left-sided extrahepatic portal hypertension

scientific article published on 13 August 2010

A long-term recurrence-free survival of a patient with the mixed adeno-neuroendocrine bile duct carcinoma: A case report and review of the literature.

scientific article published on 4 August 2017

A mouse model of autoimmune pancreatitis with salivary gland involvement triggered by innate immunity via persistent exposure to avirulent bacteria

scientific article published on 23 August 2010

A primary tumor of mixed histological type is a novel poor prognostic factor for patients undergoing resection of liver metastasis from gastric cancer

scientific article

A statement by the Japan-Korea expert pathologists for future clinicopathological and molecular analyses toward consensus building of intraductal papillary neoplasm of the bile duct through several opinions at the present stage.

scientific article

APAF-1-ALT, a novel alternative splicing form of APAF-1, potentially causes impeded ability of undergoing DNA damage-induced apoptosis in the LNCaP human prostate cancer cell line.

scientific article published on June 2003

Aberrant (pro)renin receptor expression induces genomic instability in pancreatic ductal adenocarcinoma through upregulation of SMARCA5/SNF2H

scientific article published on 27 November 2020

Abrogation of DUSP6 by hypermethylation in human pancreatic cancer

scientific article (publication date: 2005)

Activation of STAT5 confers imatinib resistance on leukemic cells through the transcription of TERT and MDR1 ⬇️

scientific article published on February 26, 2011

Association of epidermal growth factor receptor and mitogen-activated protein kinase with cystic neoplasms of the pancreas.

scientific article published on 21 May 2010

Characteristic clinicopathological features of the types of intraductal papillary-mucinous neoplasms of the pancreas.

scientific article published in November 2007

Chromosome 12, frequently deleted in human pancreatic cancer, may encode a tumor-suppressor gene that suppresses angiogenesis.

scientific article published on October 2004

Classification of types of intraductal papillary-mucinous neoplasm of the pancreas: a consensus study

scientific article

Clinical and pathological features of solid pseudopapillary neoplasms of the pancreas at a single institution

scientific article published on 21 June 2014

Clinical relevance of frozen diagnosis of ductal margins in surgery of bile duct cancer

scientific article published on 21 January 2014

Clinicopathological characteristics and molecular analyses of multifocal intraductal papillary mucinous neoplasms of the pancreas

scientific article

Clinicopathological significance of somatic RNF43 mutation and aberrant expression of ring finger protein 43 in intraductal papillary mucinous neoplasms of the pancreas

scientific article published on 01 August 2014

Cloning and characterization of the human UDP-N-acetylglucosamine: alpha-1,3-D-mannoside beta-1,4-N-acetylglucosaminyltransferase IV-homologue (hGnT-IV-H) gene.

scientific article published on January 1999

Cystic neoplasm of the pancreas: a Japanese multiinstitutional study of intraductal papillary mucinous tumor and mucinous cystic tumor

scientific article published on 01 April 2004

Diagnosis by 64-Row Multidetector Computed Tomography for Longitudinal Superficial Extension of Distal Cholangiocarcinoma

scientific article published on 26 November 2018

Diagnostic and Prognostic Impact of Neutrophil-to-Lymphocyte Ratio for Intraductal Papillary Mucinous Neoplasms of the Pancreas With High-Grade Dysplasia and Associated Invasive Carcinoma

scientific article published on 01 January 2019

Duodenum-preserving total pancreatectomy for pancreatic neoplasms

scientific article published on 29 October 2009

ENBD is Associated with Decreased Tumor Dissemination Compared to PTBD in Perihilar Cholangiocarcinoma.

scientific article published on 18 July 2017

Examination of Prognostic Factors Affecting Long-Term Survival of Patients with Stage 3/4 Gallbladder Cancer without Distant Metastasis

scientific article published on 27 July 2020

Exclusion of SMAD4 mutation as an early genetic change in human pancreatic ductal tumorigenesis.

scientific article published in July 2001

Feedback regulation of DUSP6 transcription responding to MAPK1 via ETS2 in human cells.

scientific article published on 9 October 2008

GNAS(R201H) and Kras(G12D) cooperate to promote murine pancreatic tumorigenesis recapitulating human intraductal papillary mucinous neoplasm.

scientific article published on 10 August 2015

Genomic Sequencing Identifies ELF3 as a Driver of Ampullary Carcinoma

scientific article

Germline mutations in Japanese familial pancreatic cancer patients

scientific article published on 06 October 2016

High-grade dysplasia/carcinoma in situ of the bile duct margin in patients with surgically resected node-negative perihilar cholangiocarcinoma is associated with poor survival: a retrospective study.

scientific article published on 26 May 2017

Hot water extract of Agaricus blazei Murrill specifically inhibits growth and induces apoptosis in human pancreatic cancer cells

scientific article published on 04 December 2018

How does intestinal-type intraductal papillary mucinous neoplasm emerge? CDX2 plays a critical role in the process of intestinal differentiation and progression

scientific article published on 15 April 2020

Human BAC Contig Covering the Deleted Region in Pancreatic Cancer at 12q21 ⬇️

scientific article published on January 1, 2001

Identification of commensal flora-associated antigen as a pathogenetic factor of autoimmune pancreatitis

scientific article

Imaging studies of intraductal tubulopapillary neoplasms of the pancreas: 2-tone duct sign and cork-of-wine-bottle sign as indicators of intraductal tumor growth

scientific article published on 01 November 2012

Impact of loss-of-function mutations at the RNF43 locus on colorectal cancer development and progression

scientific article published on 20 June 2018

Impacts of activation of the mitogen-activated protein kinase pathway in pancreatic cancer

scientific article

Improved surgical outcomes for hilar cholangiocarcinoma: changes in surgical procedures and related outcomes based on 40 years of experience at a single institution

scientific article published on 05 February 2015

Increased expression of thymic stromal lymphopoietin and its receptor in Kimura's disease

scientific article published on 11 February 2015

Infrequent mutation of APC, AXIN1, and GSK3B in human pituitary adenomas with abnormal accumulation of CTNNB1.

scientific article

Infrequent somatic mutations of the p73 gene in various human cancers

scientific article published in April 1999

Inhibition of 15-PGDH causes Kras-driven tumor expansion through prostaglandin E2-ALDH1 signaling in the pancreas

scientific article published on 24 September 2018

Insulinoma with six islet cell tumors associated with severe hypoglycemia.

scientific article

Intracholecystic papillary-tubular neoplasm of the gallbladder originating in the cystic duct with extensive intraepithelial progress in the common bile duct

scientific article published on 30 November 2018

Intraductal papillary mucinous tumors of the pancreas comprise 2 clinical subtypes: differences in clinical characteristics and surgical management

scientific article published on 01 October 1999

Intraductal papillary neoplasms of the bile duct consist of two distinct types specifically associated with clinicopathological features and molecular phenotypes

scientific article published on 26 February 2020

Intraductal papillary-mucinous adenocarcinoma in the remnant pancreas after pancreatoduodenectomy for cancer of Vater's papilla associated with intraductal papillary-mucinous adenoma

scientific article

Intraductal tubular carcinoma of the pancreas: case report with molecular analysis

scientific article published in March 2009

Intraductal tubulopapillary neoplasm of the pancreas with somatic BRAF mutation.

scientific article published on 15 November 2012

Intraductal tubulopapillary neoplasms of the pancreas distinct from pancreatic intraepithelial neoplasia and intraductal papillary mucinous neoplasms

scientific article published on 01 August 2009

Loss of MKP3 mediated by oxidative stress enhances tumorigenicity and chemoresistance of ovarian cancer cells

scientific article published on 16 July 2008

Metachronous intraductal papillary mucinous neoplasms disseminate via the pancreatic duct following resection

scientific article published on 13 November 2019

MicroRNAs associated with mitogen-activated protein kinase in human pancreatic cancer.

scientific article

Molecular biomarkers for progression of intraductal papillary mucinous neoplasm of the pancreas

scientific article published in March 2015

Molecular characteristics and biological behaviours of the oncocytic and pancreatobiliary subtypes of intraductal papillary mucinous neoplasms.

scientific article

Molecular events in human T cells treated with diesel exhaust particles or formaldehyde that underlie their diminished interferon-gamma and interleukin-10 production.

scientific article

Molecular genetics of intraductal papillary-mucinous neoplasms of the pancreas.

scientific article published on 29 May 2007

Molecular mechanisms of pancreatic carcinogenesis.

scientific article

Multicenter study of early pancreatic cancer in Japan

scientific article published on 20 November 2017

Mutation analyses by next-generation sequencing and multiplex ligation-dependent probe amplification in Japanese autosomal dominant polycystic kidney disease patients

scientific article published on 15 April 2019

Mutation of junctophilin type 2 associated with hypertrophic cardiomyopathy

scientific article

Mutations in BRCA1, BRCA2, and PALB2, and a panel of 50 cancer-associated genes in pancreatic ductal adenocarcinoma.

scientific article

Near-Comprehensive Resequencing of Cancer-Associated Genes in Surgically Resected Metastatic Liver Tumors of Gastric Cancer

scientific article published on 29 January 2019

Novel biomarkers distinguishing pancreatic head Cancer from distal cholangiocarcinoma based on proteomic analysis

scientific article published on 05 April 2019

Novel compound heterozygous mutations of POLR3A revealed by whole-exome sequencing in a patient with hypomyelination

scientific article published on 18 May 2013

Original Scientific Reports: Clinicopathological Findings of Remnant Pancreatic Cancers in Survivors Following Curative Resections of Pancreatic Cancers

scientific article published on 20 November 2015

PTEN1 is frequently mutated in primary endometrial carcinomas

scientific article (publication date: October 1997)

PTOV1: a novel testosterone-induced atherogenic gene in human aorta

scientific article published in August 2006

Pancreatic Ductal Adenocarcinoma Derived From IPMN and Pancreatic Ductal Adenocarcinoma Concomitant With IPMN ⬇️

scientific article published on May 1, 2011

Pancreatic intraductal tubulopapillary neoplasm is genetically distinct from intraductal papillary mucinous neoplasm and ductal adenocarcinoma

scientific article

Pathologic Evaluation and Reporting of Intraductal Papillary Mucinous Neoplasms of the Pancreas and Other Tumoral Intraepithelial Neoplasms of Pancreatobiliary Tract: Recommendations of Verona Consensus Meeting

scientific article

Pathology of genetically engineered mouse models of pancreatic exocrine cancer: consensus report and recommendations.

scientific article

Pathways of Progression From Intraductal Papillary Mucinous Neoplasm to Pancreatic Ductal Adenocarcinoma Based on Molecular Features

scientific article published on 17 October 2018

Potential tumor suppressive pathway involving DUSP6/MKP-3 in pancreatic cancer

scientific article

Prognostic relevance of ductal margins in operative resection of bile duct cancer

scientific article published on 08 February 2010

Prognostic relevance of morphological types of intraductal papillary mucinous neoplasms of the pancreas

scientific article published on 30 December 2010

RNA interference targeting against S100A4 suppresses cell growth and motility and induces apoptosis in human pancreatic cancer cells

scientific article published on 30 September 2009

RNA interference targeting aurora kinase a suppresses tumor growth and enhances the taxane chemosensitivity in human pancreatic cancer cells.

scientific article

Recessive RYR1 mutations in a patient with severe congenital nemaline myopathy with ophthalomoplegia identified through massively parallel sequencing

scientific article published on 09 March 2012

Relationship between pancreatic intraepithelial neoplasias, pancreatic ductal adenocarcinomas, and single nucleotide polymorphisms in autopsied elderly patients

scientific article published on 22 June 2017

Restoration of SMAD4 by gene therapy reverses the invasive phenotype in pancreatic adenocarcinoma cells.

scientific article published in October 2003

Role of BRCA1-associated protein (BRAP) variant in childhood pulmonary arterial hypertension

scientific article published in PLoS ONE

Single nucleotide variations in CLCN6 identified in patients with benign partial epilepsies in infancy and/or febrile seizures

scientific article

Somatic mutations and increased lymphangiogenesis observed in a rare case of intramucosal gastric carcinoma with lymph node metastasis

scientific article

Somatic mutations in PIK3CA and activation of AKT in intraductal tubulopapillary neoplasms of the pancreas.

scientific article

Specific MAPK-Associated MicroRNAs in Serum Differentiate Pancreatic Cancer from Autoimmune Pancreatitis

scientific article

Subtyping of IPMN

scientific article published on 01 January 2019

Suppression of the tumorigenic phenotype by chromosome 18 transfer into pancreatic cancer cell lines

scientific article published on 01 June 2002

Surgery in node-positive gallbladder cancer: The implication of an involved superior retro-pancreatic lymph node

scientific article published on 19 October 2018

Surgical Outcomes for Perihilar Cholangiocarcinoma with Vascular Invasion

scientific article published on 10 September 2018

Synchronous and metachronous extrapancreatic malignant neoplasms in patients with intraductal papillary-mucinous neoplasm of the pancreas

scientific article published on 29 September 2008

Targeting of MAPK-associated molecules identifies SON as a prime target to attenuate the proliferation and tumorigenicity of pancreatic cancer cells

scientific article

The PMAIP1 gene on chromosome 18 is a candidate tumor suppressor gene in human pancreatic cancer.

scientific article published on 31 January 2008

The PTEN, BAX, and IGFIIR genes are mutated in endometrial atypical hyperplasia.

scientific article published in October 1998

The Prevalence and Clinicopathological Characteristics of High-Grade Pancreatic Intraepithelial Neoplasia: Autopsy Study Evaluating the Entire Pancreatic Parenchyma.

scientific article published on 14 February 2017

The discrete nature and distinguishing molecular features of pancreatic intraductal tubulopapillary neoplasms and intraductal papillary mucinous neoplasms of the gastric type, pyloric gland variant.

scientific article published in November 2013

The role of chromosome 18 abnormalities in the progression of pancreatic adenocarcinoma.

scientific article published in April 2004

Transcriptional silencing of ETS-1 efficiently suppresses angiogenesis of pancreatic cancer.

scientific article published on 5 September 2008

Transrepression activity of T-box1 in a gene regulation network in mouse cells.

scientific article

Upregulation of IGF2 is associated with an acquired resistance for cis-diamminedichloroplatinum in human head and neck squamous cell carcinoma.

scientific article

Usefulness of cell block cytology for preoperative grading and typing of intraductal papillary mucinous neoplasms ⬇️

scientific article published on June 22, 2013

Whole exome sequencing and establishment of an organoid culture of the carcinoma showing thymus-like differentiation (CASTLE) of the parotid gland

scientific article published on 07 January 2021

Whole exome sequencing reveals recurrent mutations in BRCA2 and FAT genes in acinar cell carcinomas of the pancreas

scientific article

Whole-exome sequencing identifies a de novo TUBA1A mutation in a patient with sporadic malformations of cortical development: a case report

scientific article

Whole-exome sequencing of a unique brain malformation with periventricular heterotopia, cingulate polymicrogyria and midbrain tectal hyperplasia.

scientific article

Whole-exome sequencing uncovers frequent GNAS mutations in intraductal papillary mucinous neoplasms of the pancreas.

scientific article published on 18 November 2011

[Pancreatic cancer precursor lesions]

scientific article published on 01 August 2015

p24/ING1-ALT1 and p47/ING1-ALT2, distinct alternative transcripts of p33/ING1

scientific article (publication date: 2000)

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