Search filters

List of works by David B. Lombard

"MPNST Epigenetics"-Response

scientific article published on 01 October 2019

A role for the NAD-dependent deacetylase Sirt1 in the regulation of autophagy

scientific article

ACSF3 and Mal(onate)-Adapted Mitochondria

scientific article published in June 2017

Acetyl-ed question in mitochondrial biology?

scientific article published on 14 September 2015

Ageing: longevity hits a roadblock

scientific article

Analysis of the Role of RecQ Helicases in RNAi in Mammals

scientific article published on 01 March 2002

C. elegans SIRT6/7 homolog SIR-2.4 promotes DAF-16 relocalization and function during stress

scientific article (publication date: September 2012)

Calorie restriction alters mitochondrial protein acetylation

scientific article published on 9 July 2009

Combined MAPK Pathway and HDAC Inhibition Breaks Melanoma

scientific article published on 01 April 2019

Cross-talk between sirtuin and mammalian target of rapamycin complex 1 (mTORC1) signaling in the regulation of S6 kinase 1 (S6K1) phosphorylation

scientific article

Cycling around Lysine Modifications

scientific article published on 5 June 2017

DNA repair, genome stability, and aging

scientific article

Defective DNA repair and increased genomic instability in Artemis-deficient murine cells

scientific journal article

Essential role of limiting telomeres in the pathogenesis of Werner syndrome

scientific journal article

Finding Ponce de Leon's Pill: Challenges in Screening for Anti-Aging Molecules

scientific article

For Certain, SIRT4 Activities!

scientific article published on 3 June 2017

GPR1 and CMKLR1 control lipid metabolism to support development of clear cell renal cell carcinoma

scientific article published on 19 April 2024

Generation and Purification of Catalytically Active Recombinant Sirtuin5 (SIRT5) Protein

scientific article published on January 2016

H2AX prevents DNA breaks from progressing to chromosome breaks and translocations

scientific article published in January 2006

High-throughput small molecule screening reveals Nrf2-dependent and -independent pathways of cellular stress resistance

scientific article published on 02 October 2020

Identification of sirtuin 5 inhibitors by ultrafast microchip electrophoresis using nanoliter volume samples

scientific article

Interplay between sirtuins, MYC and hypoxia-inducible factor in cancer-associated metabolic reprogramming

scientific article

Leaky Scid phenotype associated with defective V(D)J coding end processing in Artemis-deficient mice

scientific journal article

Lysine glutarylation is a protein posttranslational modification regulated by SIRT5

scientific article

Malignant Peripheral Nerve Sheath Tumors: From Epigenome to Bedside

scientific article published on 25 April 2019

Mammalian SIRT1 limits replicative life span in response to chronic genotoxic stress

scientific article

Mammalian Sir2 homolog SIRT3 regulates global mitochondrial lysine acetylation

scientific journal article

Mass spectrometry-based detection of protein acetylation

scientific article

Metabolic Regulation of Gene Expression by Histone Lysine β-Hydroxybutyrylation

scientific article

Mice lacking histone deacetylase 6 have hyperacetylated tubulin but are viable and develop normally

scientific article

Mitochondrial SIRT4-type proteins in Caenorhabditis elegans and mammals interact with pyruvate carboxylase and other acetylated biotin-dependent carboxylases

scientific article published on 21 February 2013

Mitochondrial sirtuins and their relationships with metabolic disease and cancer

scientific article

Mitochondrial sirtuins in the regulation of mitochondrial activity and metabolic adaptation

scientific article published on January 2011

Neural sirtuin 6 (Sirt6) ablation attenuates somatic growth and causes obesity

scientific article

Nucleolar localization of the Werner syndrome protein in human cells ⬇️

scientific article published on June 9, 1998

Proteomic and Biochemical Studies of Lysine Malonylation Suggest Its Malonic Aciduria-associated Regulatory Role in Mitochondrial Function and Fatty Acid Oxidation

scientific article

Retraction Note to: Retraction: The NAD-dependent deacetylase SIRT2 is required for programmed necrosis

scientific article published on 01 February 2014

SIRT3 Deacetylates Ceramide Synthases: IMPLICATIONS FOR MITOCHONDRIAL DYSFUNCTION AND BRAIN INJURY.

scientific article

SIRT3 as a regulator of hepatic autophagy

article published in 2017

SIRT3 deacetylates mitochondrial 3-hydroxy-3-methylglutaryl CoA synthase 2 and regulates ketone body production

scientific article

SIRT3 regulates mitochondrial fatty-acid oxidation by reversible enzyme deacetylation

scientific article

SIRT3-dependent deacetylation exacerbates acetaminophen hepatotoxicity

scientific journal article

SIRT3: as simple as it seems?

scientific article published on 25 October 2013

SIRT5-mediated lysine desuccinylation impacts diverse metabolic pathways

scientific article

Sirtuin 1 Regulates Dendritic Cell Activation and Autophagy during Respiratory Syncytial Virus-Induced Immune Responses

scientific article published on 8 July 2015

Sirtuin 1 regulates mitochondrial function and immune homeostasis in respiratory syncytial virus infected dendritic cells

scientific article published on 27 February 2020

Sirtuin-3 (Sirt3) regulates skeletal muscle metabolism and insulin signaling via altered mitochondrial oxidation and reactive oxygen species production

scientific article

Sirtuins: guardians of mammalian healthspan

scientific article

Sorting out the sirtuins

scientific article published on 07 March 2012

Structure, expression, and T cell costimulatory activity of the murine homologue of the human B lymphocyte activation antigen B7

scientific article

Telomere shortening exposes functions for the mouse Werner and Bloom syndrome genes

scientific journal article

The NAD-dependent deacetylase SIRT2 is required for programmed necrosis

scientific journal article

The first identification of lysine malonylation substrates and its regulatory enzyme ⬇️

scientific article

The histone deacetylase SIRT6 is a tumor suppressor that controls cancer metabolism

scientific article

The sirtuin SIRT6 blocks IGF-Akt signaling and development of cardiac hypertrophy by targeting c-Jun

scientific article

Paulina is supported by:

About Paulina

Help