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List of works by Chul-Ho Yun

A dual function of the furanocoumarin chalepensin in inhibiting Cyp2a and inducing Cyp2b in mice: the protein stabilization and receptor-mediated activation

scientific article

Affinity purification of recombinant human cytochrome P450s 3A4 and 1A2 using mixed micelle systems.

scientific article

An NH2-terminal truncated cytochrome P450 CYP3A4 showing catalytic activity is present in the cytoplasm of human liver cells

scientific article

Anionic phospholipid-induced regulation of reactive oxygen species production by human cytochrome P450 2E1.

scientific article published on 8 May 2008

Bacillus spore display

scientific article published on 17 October 2012

Bacterial β-(1,3)-glucan prevents DSS-induced IBD by restoring the reduced population of regulatory T cells.

scientific article published on 21 July 2014

Beta sheet 2-alpha helix C loop of cytochrome P450 reductase serves as a docking site for redox partners.

scientific article

Biochemical analysis of recombinant CYP4A11 allelic variant enzymes: W126R, K276T and S353G.

scientific article published on 19 September 2016

Ca(2+)-induced stimulation of the membrane binding of Escherichia coli SecA and its association with signal peptides of secretory proteins.

scientific article published on 19 April 2009

Ca2+/H+ antiporter-like activity of human recombinant Bax inhibitor-1 reconstituted into liposomes.

scientific article published on 05 March 2009

Cargo-Free Nanoparticles Containing Cationic Lipids Induce Reactive Oxygen Species and Cell Death in HepG2 Cells.

scientific article published in January 2016

Characterization of a Biflaviolin Synthase CYP158A3 from Streptomyces avermitilis and Its Role in the Biosynthesis of Secondary Metabolites.

scientific article published on 13 December 2016

Characterization of diverse natural variants of CYP102A1 found within a species of Bacillus megaterium.

scientific article

Chimeric cytochromes P450 engineered by domain swapping and random mutagenesis for producing human metabolites of drugs

scientific article published on 13 February 2014

Cofactor-free light-driven whole-cell cytochrome P450 catalysis

scientific article published on 27 November 2014

Conformational change and activation of cytochrome P450 2B1 induced by salt and phospholipid.

scientific article

Conformational change of cytochrome P450 1A2 induced by phospholipids and detergents

scientific article published on 01 August 1997

Conformational change of cytochrome P450 1A2 induced by sodium chloride

scientific article published on 01 December 1996

Continuous spectrofluorometric and spectrophotometric assays for NADPH-cytochrome P450 reductase activity using 5-cyano-2,3-ditolyl tetrazolium chloride.

scientific article

Contributions of human liver cytochrome P450 enzymes to the N-oxidation of 4,4′-methylene-bis(2-chloroaniline) ⬇️

scientific article published on February 1, 1992

Crystal structure of cytochrome P450 CYP105N1 from Streptomyces coelicolor, an oxidase in the coelibactin siderophore biosynthetic pathway

scientific article

Cytochrome P450 2E1 and 2A6 enzymes as major catalysts for metabolic activation of N-nitrosodialkylamines and tobacco-related nitrosamines in human liver microsomes

scientific article published on October 1, 1992

Decreased level of albumin in peripheral blood mononuclear cells of streptozotocin-induced diabetic rats.

scientific article

Development of peptide substrates for trypsin based on monomer/excimer fluorescence of pyrene.

scientific article

Differential gene expression profiles in spontaneously hypertensive rats induced by administration of enalapril and nifedipine

scientific article published on 15 November 2012

Directed evolution reveals requisite sequence elements in the functional expression of P450 2F1 in Escherichia coli

scientific article

Doxorubicin- and daunorubicin-induced regulation of Ca2+ and H+ fluxes through human bax inhibitor-1 reconstituted into membranes.

scientific article

Effects of Lipids on the Interaction of SecA with Model Membranes ⬇️

scientific article published on November 1, 2001

Effects of aqueous extract of Ruta graveolens and its ingredients on cytochrome P450, uridine diphosphate (UDP)-glucuronosyltransferase, and reduced nicotinamide adenine dinucleotide (phosphate) (NAD(P)H)-quinone oxidoreductase in mice

scientific article published on 21 May 2015

Effects of flupyrazofos on liver microsomal cytochrome P450 in the male Fischer 344 rat.

scientific article published in December 2000

Effects of phospholipids on the functional regulation of tBID in membranes

scientific article published on 22 December 2011

Effects of β-ionone on the expression of cytochrome P450s and NADPH-cytochrome P450 reductase in Sprague Dawley rats ⬇️

scientific article published on July 3, 1998

Engineering bacterial cytochrome P450 (P450) BM3 into a prototype with human P450 enzyme activity using indigo formation

scientific article

Enhanced expression of human cytochrome P450 1A2 by co-expression with human molecular chaperone Hsp70.

scientific article

Estrogen-related receptor γ controls hepatic CB1 receptor-mediated CYP2E1 expression and oxidative liver injury by alcohol.

scientific article published on 29 September 2012

Evidence for a 1-electron oxidation mechanism in N-dealkylation of N,N-dialkylanilines by cytochrome P450 2B1. Kinetic hydrogen isotope effects, linear free energy relationships, comparisons with horseradish peroxidase, and studies with oxygen surro

scientific article published on 01 November 1996

Expression of CYP2A6, CYP2D6 and CYP4A11 Polymorphisms in COS7 Mammalian Cell Line.

scientific article published on March 2011

Functional Significance of Cytochrome P450 1A2 Allelic Variants, P450 1A2*8, *15, and *16 (R456H, P42R, and R377Q).

scientific article published in March 2015

Functional and conformational modulation of human cytochrome P450 1B1 by anionic phospholipids.

scientific article published on 24 October 2009

Functional characterization of CYP107W1 from Streptomyces avermitilis and biosynthesis of macrolide oligomycin A

scientific article

Functional characterization of allelic variants of polymorphic human cytochrome P450 2A6 (CYP2A6*5, *7, *8, *18, *19, and *35).

scientific article

Functional characterization of steroid hydroxylase CYP106A1 derived from Bacillus megaterium.

scientific article

Functional expression of mammalian NADPH-cytochrome P450 oxidoreductase on the cell surface of Escherichia coli

scientific article published on 6 June 2006

Functional influence of human CYP2D6 allelic variations: P34S, E418K, S486T, and R296C.

scientific article published on 30 July 2013

Functional regulation of hepatic cytochrome p450 enzymes by physicochemical properties of phospholipids in biological membranes.

scientific article published on October 2007

Generation of human chiral metabolites of simvastatin and lovastatin by bacterial CYP102A1 mutants

scientific article

Heme-thiolate sulfenylation of human cytochrome P450 4A11 functions as a redox switch for catalytic inhibition.

scientific article published on 22 May 2017

Heterologous expression and characterization of the sterol 14α-demethylase CYP51F1 from Candida albicans ⬇️

scientific article published on February 17, 2011

Heterologous expression and functional characterization of the NADPH-cytochrome P450 reductase from Capsicum annuum

scientific article published on 4 June 2014

High-level expression of human cytochrome P450 1A2 by co-expression with human molecular chaperone HDJ-1(Hsp40).

scientific article published in July 2004

Highly regioselective hydroxylation of polydatin, a resveratrol glucoside, for one-step synthesis of astringin, a piceatannol glucoside, by P450 BM3.

scientific article published on 9 November 2016

Hydroxywarfarin metabolites potently inhibit CYP2C9 metabolism of S-warfarin

scientific article

Identification of cytochrome P450 1A1 in human brain.

scientific article

Identification of cytochrome P450 2E1 in rat brain.

scientific article published in February 1997

Importance of phosphatidylethanolamine for the interaction of apocytochrome c with model membranes containing phosphatidylserine

scientific article published on 01 August 2000

Improved long-term cryostorage of Escherichia coli competent cells using trehalose.

scientific article published in October 2004

Increase of human CYP1B1 activities by acidic phospholipids and kinetic deuterium isotope effects on CYP1B1 substrate oxidation ⬇️

scientific article published on August 9, 2012

Induction of liver cytochrome P450 2B1 by beta-ionone in Sprague Dawley rats

scientific article published on 01 November 1995

Induction of rat hepatic cytochrome P450 enzymes by myristicin

scientific article published on 01 December 1995

Inhibition of CYP4A reduces hepatic endoplasmic reticulum stress and features of diabetes in mice

scientific article published on 28 June 2014

Inhibition of human cytochrome P450 3A4 activity by zinc(II) ion.

scientific article

Inhibitory effect of anethole on T-lymphocyte proliferation and interleukin-2 production through down-regulation of the NF-AT and AP-1.

scientific article published on 13 March 2006

Interleukin-24 attenuates β-glycerophosphate-induced calcification of vascular smooth muscle cells by inhibiting apoptosis, the expression of calcification and osteoblastic markers, and the Wnt/β-catenin pathway

scientific article published on 11 October 2012

Involvement of P4503A in the metabolism of 7,8-benzoflavone by human liver microsomes

scientific article published on 01 November 1994

Kinetic analysis of lauric acid hydroxylation by human cytochrome P450 4A11

scientific article

Kinetic analysis of oxidation of coumarins by human cytochrome P450 2A6.

scientific article published on 22 January 2005

Kinetic deuterium isotope effects for 7-alkoxycoumarin O-dealkylation reactions catalyzed by human cytochromes P450 and in liver microsomes. Rate-limiting C-H bond breaking in cytochrome P450 1A2 substrate oxidation

scientific article published on 01 May 2006

Lateral segregation of anionic phospholipids in model membranes induced by cytochrome P450 2B1: bi-directional coupling between CYP2B1 and anionic phospholipid.

scientific article published on 12 October 2007

Mechanism-based inactivation of cytochrome P450 2A6 by decursinol angelate isolated from Angelica Gigas

scientific article published on 09 July 2007

Membrane insertion of cytochrome P450 1A2 promoted by anionic phospholipids

scientific article published on 01 September 1998

Membrane properties induced by anionic phospholipids and phosphatidylethanolamine are critical for the membrane binding and catalytic activity of human cytochrome P450 3A4.

scientific article published in December 2003

Metabolism of R- and S-warfarin by CYP2C19 into four hydroxywarfarins

scientific article published on September 2012

Modification of cytochrome P450 1A2 enzymes by the mechanism-based inactivator 2-ethynylnaphthalene and the photoaffinity label 4-azidobiphenyl

scientific article published on 01 November 1992

Molecular mechanisms regulating the mitochondrial targeting of microsomal cytochrome P450 enzymes.

scientific article published on December 2010

Non-specific inhibition of cytochrome P450 activities by chlorophyllin in human and rat liver microsomes

scientific article published in June 1995

Novel protective mechanism against irreversible hyperoxidation of peroxiredoxin: Nalpha-terminal acetylation of human peroxiredoxin II.

scientific article published on 13 March 2009

Oxidations of p-alkoxyacylanilides catalyzed by human cytochrome P450 1A2: structure-activity relationships and simulation of rate constants of individual steps in catalysis.

scientific article published in April 2001

Peroxide-dependent oxidation reactions catalyzed by CYP191A1 from Mycobacterium smegmatis.

scientific article published on 19 May 2017

Phase properties of liquid-crystalline Phosphatidylcholine/Phosphatidylethanolamine bilayers revealed by fluorescent probes

scientific article published on 01 September 1999

Phospholipase D Activity of Cytochrome P450 in Human Liver Endoplasmic Reticulum

scientific article published on 01 July 1999

Polyacrylamide gel electrophoresis without a stacking gel: application for separation of peptides

scientific article published on 01 June 2002

Polyacrylamide gel electrophoresis without a stacking gel: use of amino acids as electrolytes.

scientific article published in April 2001

Potential in vitro Protective Effect of Quercetin, Catechin, Caffeic Acid and Phytic Acid against Ethanol-Induced Oxidative Stress in SK-Hep-1 Cells.

scientific article published on September 2012

Predicting CYP2C19 catalytic parameters for enantioselective oxidations using artificial neural networks and a chirality code ⬇️

scientific article published on April 22, 2013

Production of polyclonal antibodies against peptide antigens using polystyrene beads as a carrier

scientific article published on 13 July 2007

Purification and characterization of thiol-specific antioxidant protein from human red blood cell: a new type of antioxidant protein

scientific article

Refolding and reconstitution of human recombinant Bax inhibitor-1 into liposomes from inclusion bodies expressed in Escherichia coli

scientific article published on 22 January 2009

Regioselective C-H hydroxylation of omeprazole sulfide by Bacillus megaterium CYP102A1 to produce a human metabolite.

scientific article

Regioselective hydroxylation of 17β-estradiol by mutants of CYP102A1 from Bacillus megaterium

scientific article published on 17 August 2014

Regioselective hydroxylation of omeprazole enantiomers by bacterial CYP102A1 mutants

scientific article published on 09 July 2014

Roles of human liver cytochrome P450 3A4 and 1A2 enzymes in the oxidation of myristicin.

scientific article published in February 2003

Screening of Human CYP1A2 and CYP3A4 Inhibitors from Seaweed In Silico and In Vitro

scientific article published on 29 November 2020

Selenium supplementation restores the decreased albumin level of peripheral blood mononuclear cells in streptozotocin-induced diabetic mice.

scientific article published on 03 January 2016

Structural Analysis of the Streptomyces avermitilis CYP107W1-Oligomycin A Complex and Role of the Tryptophan 178 Residue ⬇️

scientific article published on 16 February 2016

Structural insights into the binding of lauric acid to CYP107L2 from Streptomyces avermitilis

scientific article published on 24 November 2016

Suppression of interleukin-2 gene expression by isoeugenol is mediated through down-regulation of NF-AT and NF-kappaB

scientific article published on 15 June 2007

The Flavin-Containing Reductase Domain of Cytochrome P450 BM3 Acts as a Surrogate for Mammalian NADPH-P450 Reductase.

scientific article

The bacterial P450 BM3: a prototype for a biocatalyst with human P450 activities

scientific article published on 29 May 2007

The role of cytochrome P450 2B6 and 2B4 substrate access channel residues predicted based on crystal structures of the amlodipine complexes

scientific article

Transformation of Escherichia coli and protein expression using lipoplex mimicry

scientific article published on 11 July 2016

Trehalose increases chemical-induced transformation efficiency of Escherichia coli.

scientific article published in October 2004

Triggering receptor expressed on myeloid cells 2 (TREM2) promotes adipogenesis and diet-induced obesity.

scientific article published on 11 August 2014

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