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List of works by Nancy C Horton

Activation of DNA Cleavage by Oligomerization of DNA-Bound SgrAI ⬇️

scientific article published on October 19, 2010

Allosteric Regulation of DNA Cleavage and Sequence-Specificity through Run-On Oligomerization

scientific article

Alteration of sequence specificity of the type II restriction endonuclease HincII through an indirect readout mechanism

scientific article published on 04 May 2006

Ca2+ binding in the active site of HincII: implications for the catalytic mechanism

scientific article published in October 2004

Calculation of the free energy of association for protein complexes

scientific article published on January 1992

Catalytic efficiency and sequence selectivity of a restriction endonuclease modulated by a distal manganese ion binding site.

scientific article

Cation binding to the integrin CD11b I domain and activation model assessment

scientific article

Crystallization and preliminary diffraction analysis of the HincII restriction endonuclease-DNA complex.

scientific article published on November 1999

Crystallization of zinc finger proteins bound to DNA

scientific article published on 01 January 2010

DNA cleavage by EcoRV endonuclease: two metal ions in three metal ion binding sites.

scientific article

DNA-induced conformational changes in type II restriction endonucleases: the structure of unliganded HincII

scientific article published on 01 August 2005

Divalent metal dependence of site-specific DNA binding by EcoRV endonuclease.

scientific article

Domain Swapping in Allosteric Modulation of DNA Specificity

scientific article

Electrostatic contributions to site specific DNA cleavage by EcoRV endonuclease.

scientific article published in September 2002

Escherichia coli lac repressor-lac operator interaction and the influence of allosteric effectors.

scientific article

Making the most of metal ions

scientific article published on 01 April 2001

Mechanistic insights from the structures of HincII bound to cognate DNA cleaved from addition of Mg2+ and Mn2+.

scientific article published in October 2004

Metal ion-mediated substrate-assisted catalysis in type II restriction endonucleases

scientific article

New clues in the allosteric activation of DNA cleavage bySgrAI: structures ofSgrAI bound to cleaved primary-site DNA and uncleaved secondary-site DNA ⬇️

scientific article published on December 16, 2010

Novel insights into filament-forming enzymes

scientific article published on 01 November 2019

Recognition of Flanking DNA Sequences by EcoRV Endonuclease Involves Alternative Patterns of Water-mediated Contacts ⬇️

scientific article published on August 21, 1998

Role of protein-induced bending in the specificity of DNA recognition: crystal structure of Eco RV endonuclease complexed with d(AAAGAT) + d(ATCTT) 1 1Edited by P. E. Wright ⬇️

scientific article published on April 10, 1998

Sequence selectivity and degeneracy of a restriction endonuclease mediated by DNA intercalation

scientific article

Structural analysis of activated SgrAI-DNA oligomers using ion mobility mass spectrometry.

scientific article published on 17 June 2013

Structure and specificity of FEN-1 from Methanopyrus kandleri

scientific article

Structure of Aart, a designed six-finger zinc finger peptide, bound to DNA.

scientific article published on 11 August 2006

Structures, functions, and mechanisms of filament forming enzymes: a renaissance of enzyme filamentation

scientific article published on 16 November 2019

The run-on oligomer filament enzyme mechanism of SgrAI: Part 1. Assembly kinetics of the run-on oligomer filament

scientific article published on 01 August 2018

The run-on oligomer filament enzyme mechanism of SgrAI: Part 2. Kinetic modeling of the full DNA cleavage pathway

scientific article published on 27 July 2018

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