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List of works by Liesbet Geris

A Semiquantitative Framework for Gene Regulatory Networks: Increasing the Time and Quantitative Resolution of Boolean Networks

scientific article published on 11 June 2015

A cell based modelling framework for skeletal tissue engineering applications.

scientific article

A computational model for cell/ECM growth on 3D surfaces using the level set method: a bone tissue engineering case study.

scientific article published on 3 April 2014

A flexible and easy-to-use open-source tool for designing functionally graded 3D porous structures

scientific article published in 2022

A hybrid bioregulatory model of angiogenesis during bone fracture healing.

scientific article published on 9 September 2010

A mathematical model of adult subventricular neurogenesis.

scientific article published on 9 May 2012

A mechano-regulatory model for bone healing predictions under the influence of ultrasound

scientific article published on 01 August 2015

A three-dimensional computational fluid dynamics model of shear stress distribution during neotissue growth in a perfusion bioreactor

scientific article published on 9 June 2015

A visco-elastic model for the prediction of orthodontic tooth movement

scientific article published on 12 July 2012

An Introduction to Uncertainty in the Development of Computational Models of Biological Processes

article

An open source crash course on parameter estimation of computational models using a Bayesian optimization approach

scientific article published in 2021

Angiogenesis in bone fracture healing: a bioregulatory model.

scientific article published on 19 November 2007

Application of mechanoregulatory models to simulate peri-implant tissue formation in an in vivo bone chamber.

scientific article published on 13 August 2007

Bayesian Multi-Objective Optimisation of Neotissue Growth in a Perfusion Bioreactor Set-Up

scientific article published in 2017

Bayesian Multi-Objective Optimisation with Mixed Analytical and Black-Box Functions: Application to Tissue Engineering

scientific article published in 2018

Bringing computational models of bone regeneration to the clinic

scientific article published on 21 April 2015

Cell based advanced therapeutic medicinal products for bone repair: Keep it simple?

scientific article

Changes in bone macro- and microstructure in diabetic obese mice revealed by high resolution microfocus X-ray computed tomography

scientific article published on 19 October 2016

Combinatorial Analysis of Growth Factors Reveals the Contribution of Bone Morphogenetic Proteins to Chondrogenic Differentiation of Human Periosteal Cells

scientific article published on 28 March 2016

Computational Modeling Under Uncertainty: Challenges and Opportunities

Computational Modeling and Reverse Engineering to Reveal Dominant Regulatory Interactions Controlling Osteochondral Differentiation: Potential for Regenerative Medicine

scientific article published on 13 November 2018

Computational modelling of biomaterial surface interactions with blood platelets and osteoblastic cells for the prediction of contact osteogenesis.

scientific article published on 29 September 2010

Connecting biology and mechanics in fracture healing: an integrated mathematical modeling framework for the study of nonunions.

scientific article published on 24 March 2010

Continuum-level modelling of cellular adhesion and matrix production in aggregates.

scientific article published in May 2011

Contrast-Enhanced Nanofocus X-Ray Computed Tomography Allows Virtual Three-Dimensional Histopathology and Morphometric Analysis of Osteoarthritis in Small Animal Models.

scientific article

Coupling curvature-dependent and shear stress-stimulated neotissue growth in dynamic bioreactor cultures: a 3D computational model of a complete scaffold

scientific article published on 12 January 2016

Current views on calcium phosphate osteogenicity and the translation into effective bone regeneration strategies.

scientific article published on 13 July 2012

Curvature in Biological Systems: Its Quantification, Emergence, and Implications across the Scales

scientific article published in 2023

Deciphering the combined effect of bone morphogenetic protein 6 and calcium phosphate on bone formation capacity of periosteum derived cells-based tissue engineering constructs

scientific article published on 26 September 2018

Designing optimal calcium phosphate scaffold-cell combinations using an integrative model-based approach.

scientific article published on 23 June 2011

Developmentally Engineered Callus Organoid Bioassemblies Exhibit Predictive In Vivo Long Bone Healing

scientific article published on 10 December 2019

ECHO, the executable CHOndrocyte: A computational model to study articular chondrocytes in health and disease

scientific article published on 11 December 2019

Early BMP, Wnt and Ca(2+)/PKC pathway activation predicts the bone forming capacity of periosteal cells in combination with calcium phosphates

scientific article

Effect of ultrasound on bone fracture healing: A computational bioregulatory model

scientific article published on 25 June 2018

Effect of ultrasound on bone fracture healing: A computational mechanobioregulatory model

scientific article published on 01 February 2019

Engineering 3D parallelized microfluidic droplet generators with equal flow profiles by computational fluid dynamics and stereolithographic printing

scientific article published on 16 December 2019

From Translation to Protein Degradation as Mechanisms for Regulating Biological Functions: A Review on the SLRP Family in Skeletal Tissues

scientific article published on 03 January 2020

Histodynamics of bone tissue formation around immediately loaded cylindrical implants in the rabbit.

scientific article published on 21 May 2007

Human Platelet Lysate Improves Bone Forming Potential of Human Progenitor Cells Expanded in Microcarrier-Based Dynamic Culture

scientific article published on 30 April 2019

Immersed Boundary Models for Quantifying Flow-Induced Mechanical Stimuli on Stem Cells Seeded on 3D Scaffolds in Perfusion Bioreactors

scientific article

In Silico Biology of Bone Regeneration Inside Calcium Phosphate Scaffolds

In silico biology of bone modelling and remodelling: regeneration.

scientific article published on May 2009

In silico cell and tissue science

In silico clinical trials for pediatric orphan diseases

scientific article published on 6 February 2018

In silico design of treatment strategies in wound healing and bone fracture healing.

scientific article published on June 2010

In silico tools predict effects of drugs on bone remodelling

scientific article published on 24 June 2020

Influence of controlled immediate loading and implant design on peri-implant bone formation

scientific article published in February 2007

MOSAIC: a multiscale model of osteogenesis and sprouting angiogenesis with lateral inhibition of endothelial cells

scientific article

Mathematical modeling in wound healing, bone regeneration and tissue engineering

scientific article published on 31 July 2010

Mathematical modeling of fracture healing in mice: comparison between experimental data and numerical simulation results

scientific article

Maximizing neotissue growth kinetics in a perfusion bioreactor: An in silico strategy using model reduction and Bayesian optimization

scientific article published on 4 December 2017

Mechanical loading affects angiogenesis and osteogenesis in an in vivo bone chamber: a modeling study.

scientific article published on 27 July 2010

Mechanisms of ectopic bone formation by human osteoprogenitor cells on CaP biomaterial carriers

article

Modelling towards a more holistic medicine: The Virtual Physiological Human (VPH)

scientific article published on 08 November 2019

Multifactorial Optimization of Contrast-Enhanced Nanofocus Computed Tomography for Quantitative Analysis of Neo-Tissue Formation in Tissue Engineering Constructs

scientific article published on 15 June 2015

Neurofibromatosis type 1-related pseudarthrosis: Beyond the pseudarthrosis site

scientific article published on 18 June 2019

Occurrence and treatment of bone atrophic non-unions investigated by an integrative approach

scientific article

Optimizing neotissue growth inside perfusion bioreactors with respect to culture and labor cost: a multi-objective optimization study using evolutionary algorithms

scientific article published on 29 January 2020

Oxygen as a critical determinant of bone fracture healing-a multiscale model.

scientific article published on 24 October 2014

Predicting in vitro human mesenchymal stromal cell expansion based on individual donor characteristics using machine learning

scientific article published on 25 January 2020

Regenerative orthopaedics: in vitro, in vivo...in silico.

scientific article published on 02 July 2014

Relating the chondrocyte gene network to growth plate morphology: from genes to phenotype

scientific article

Reproducible research in computational sciences: A use case for uncertainty quantification using Jupyter Notebooks

scientific article published on 28 July 2021

Simultaneous three-dimensional visualization of mineralized and soft skeletal tissues by a novel microCT contrast agent with polyoxometalate structure

scientific article published on 22 December 2017

Single-cell characterization and metabolic profiling of in vitro cultured human skeletal progenitors with enhanced in vivo bone forming capacity

scientific article published on 18 November 2019

Size does matter: an integrative in vivo-in silico approach for the treatment of critical size bone defects

scientific article

Spatial optimization in perfusion bioreactors improves bone tissue-engineered construct quality attributes.

scientific article

Staphylococcal biofilm growth on smooth and porous titanium coatings for biomedical applications.

scientific article published on 10 May 2013

The Bone-Forming Properties of Periosteum-Derived Cells Differ Between Harvest Sites

scientific article published on 25 November 2020

The Third Era of Tissue Engineering: Reversing the Innovation Drivers

scientific article published on 02 May 2019

The combined bone forming capacity of human periosteal derived cells and calcium phosphates

article

The combined mechanism of bone morphogenetic protein- and calcium phosphate-induced skeletal tissue formation by human periosteum derived cells.

scientific article published on 5 January 2016

The effect of micro-motion on the tissue response around immediately loaded roughened titanium implants in the rabbit

scientific article published in February 2007

The future is digital: In silico tissue engineering

scholarly article published June 2018

Three-dimensional characterization of tissue-engineered constructs by contrast-enhanced nanofocus computed tomography.

scientific article published on 19 October 2013

Towards Self-Regulated Bioprocessing: A Compact Benchtop Bioreactor System for Monitored and Controlled 3D Cell and Tissue Culture

scientific article published on 15 May 2019

Towards a quantitative understanding of oxygen tension and cell density evolution in fibrin hydrogels.

scientific article published on 28 September 2010

Tumor exposed-lymphatic endothelial cells promote primary tumor growth via IL6

scientific article published on 17 October 2020

Turning Nature's own processes into design strategies for living bone implant biomanufacturing: a decade of Developmental Engineering

scientific article published on 05 December 2020

Uncoupling of in-vitro identity of embryonic limb derived skeletal progenitors and their in-vivo bone forming potential

scientific article published on 08 April 2019

Verifying and Validating Quantitative Systems Pharmacology and In Silico Models in Drug Development: Current Needs, Gaps, and Challenges

scientific article published on 01 April 2020

Virtual physiological human 2016: translating the virtual physiological human to the clinic

Warning About the Use of Critical-Size Defects for the Translational Study of Bone Repair: Analysis of a Sheep Tibial Model

scientific article published on 8 June 2017

Wobble tRNA modification and hydrophilic amino acid patterns dictate protein fate

scientific article published on 15 April 2021

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