List of works - Antonella Viola

A T cell receptor (TCR) antagonist competitively inhibits serial TCR triggering by low-affinity ligands, but does not affect triggering by high-affinity anti-CD3 antibodies

scientific article published on 01 November 1997

A novel KIR-associated function: evidence that CpG DNA uptake and shuttling to early endosomes is mediated by KIR3DL2.

scientific article published on 10 February 2010

Adenosine triphosphate acts as a paracrine signaling molecule to reduce the motility of T cells.

scientific article

Adhesion shapes T cells for prompt and sustained T-cell receptor signalling.

scientific article

Administration of Human MSC-Derived Extracellular Vesicles for the Treatment of Primary Sclerosing Cholangitis: Preclinical Data in MDR2 Knockout Mice

scientific article published on 23 November 2020

Analysis of T Cell Activation by Confocal Microscopy.

scientific article

Boosting antitumor responses of T lymphocytes infiltrating human prostate cancers.

scientific article

CD4+CD25+ regulatory T cells suppress mast cell degranulation and allergic responses through OX40-OX40L interaction.

scientific article

CXCL12 Mediates Aberrant Costimulation of B Lymphocytes in Warts, Hypogammaglobulinemia, Infections, Myelokathexis Immunodeficiency.

scientific article published on 4 September 2017

CXCR4 signaling in health and disease

scientific article

Cbl-b mediates TGFβ sensitivity by downregulating inhibitory SMAD7 in primary T cells.

scientific article published on 24 May 2013

Chemokine nitration prevents intratumoral infiltration of antigen-specific T cells.

scientific article

Constitutively active Lck kinase in T cells drives antigen receptor signal transduction

scientific article

Differential involvement of α4β2, α7 and α9α10 nicotinic acetylcholine receptors in B lymphocyte activation in vitro

scientific article published on 10 December 2010

Extracellular Vesicles Secreted by Mesenchymal Stromal Cells Exert Opposite Effects to Their Cells of Origin in Murine Sodium Dextran Sulfate-Induced Colitis

scientific article published on 13 April 2021

From TCR Engagement to T Cell Activation

scientific article published on 01 January 1999

From tango to quadrilla: current views of the immunological synapse.

scientific article published on 07 January 2007

GM-CSF Nitration Is a New Driver of Myeloid Suppressor Cell Activity in Tumors

scientific article published on 05 October 2021

Human Immunodeficiencies Related to Defective APC/T Cell Interaction

scientific article

Hypoxia-mediated regulation of macrophage functions in pathophysiology

scientific article

IL1β Promotes TMPRSS2 Expression and SARS-CoV-2 Cell Entry Through the p38 MAPK-GATA2 Axis

scientific article published on 07 December 2021

Identification of a novel agrin-dependent pathway in cell signaling and adhesion within the erythroid niche

scientific article published on 18 March 2016

Innate immunity ascertained from blood and tracheal aspirates of preterm newborn provides new clues for assessing bronchopulmonary dysplasia

scientific article published on 04 September 2019

Intercellular Calcium Signaling Induced by ATP Potentiates Macrophage Phagocytosis

scientific article published on 01 April 2019

Lipid rafts in lymphocyte activation.

scientific article published on June 2004

Membrane Rafts in T Cell Activation: A Spotlight on CD28 Costimulation

scientific article

Mesenchymal stem cells: myths and reality

scientific article

Metabolic mechanisms of cancer-induced inhibition of immune responses.

scientific article published on 23 June 2007

Modulation of human T-cell functions by reactive nitrogen species

scientific article published on 07 June 2011

Mouse mesenchymal stem cells inhibit high endothelial cell activation and lymphocyte homing to lymph nodes by releasing TIMP-1.

scientific article

Orchestration of lymphocyte chemotaxis by mitochondrial dynamics

scientific article

Phosphatidylinositol 4-Phosphate 5-Kinase β Controls Recruitment of Lipid Rafts into the Immunological Synapse

scientific article

Phosphatidylinositol 4-Phosphate 5-Kinases in the Regulation of T Cell Activation

scientific article

Phosphatidylinositol 4-phosphate 5-kinase α and Vav1 mutual cooperation in CD28-mediated actin remodeling and signaling functions

scientific article published on 24 December 2014

Physiological T cell activation starts and propagates in lipid rafts.

scientific article published in January 2004

Prostate cancer-induced immunodysfunction: a lesson from organ cultures

scientific article published on 01 August 2005

Proteomic analysis of the secretome of human bone marrow-derived mesenchymal stem cells primed by pro-inflammatory cytokines

scientific article

Regulatory T cells target chemokine secretion by dendritic cells independently of their capacity to regulate T cell proliferation

scientific article published on 13 May 2011

Self-antigen presentation by mouse B cells results in regulatory T-cell induction rather than anergy or clonal deletion

scientific article published on 07 June 2011

Smoothing T cell roads to the tumor: Chemokine post-translational regulation.

scientific article published on May 2012

T Cells and Cancer: How Metabolism Shapes Immunity

scientific article

T cell activation determined by T cell receptor number and tunable thresholds.

scientific article

T cell costimulation by chemokine receptors

scientific article published on 10 April 2005

T cells and their partners: The chemokine dating agency.

scientific article published on 21 July 2006

T lymphocyte costimulation mediated by reorganization of membrane microdomains

scientific article

T-cell activation and the dynamic world of rafts

scientific article

Tether and trap: regulation of membrane-raft dynamics by actin-binding proteins.

scientific article published on November 2007

The Kinase PKCα Selectively Upregulates Interleukin-17A during Th17 Cell Immune Responses ⬇️

scientific article published on January 3, 2013

The Metabolic Signature of Macrophage Responses

scientific article published on 03 July 2019

The critical role of agrin in the hematopoietic stem cell niche.

scientific article

The pros and cons of chemokines in tumor immunology.

scientific article published on 20 June 2012

The raft marker GM1 identifies functional subsets of granular lymphocytes in patients with CD3+ lymphoproliferative disease of granular lymphocytes

scientific article published on 01 April 2004

Tunable chemokine production by antigen presenting dendritic cells in response to changes in regulatory T cell frequency in mouse reactive lymph nodes.

scientific article

Tuning cancer fate: the unremitting role of host immunity.

scientific article published on April 2017

List of works by Antonella Viola

A T cell receptor (TCR) antagonist competitively inhibits serial TCR triggering by low-affinity ligands, but does not affect triggering by high-affinity anti-CD3 antibodies

A novel KIR-associated function: evidence that CpG DNA uptake and shuttling to early endosomes is mediated by KIR3DL2.

Adenosine triphosphate acts as a paracrine signaling molecule to reduce the motility of T cells.

Adhesion shapes T cells for prompt and sustained T-cell receptor signalling.

Administration of Human MSC-Derived Extracellular Vesicles for the Treatment of Primary Sclerosing Cholangitis: Preclinical Data in MDR2 Knockout Mice

Analysis of T Cell Activation by Confocal Microscopy.

Boosting antitumor responses of T lymphocytes infiltrating human prostate cancers.

CD4+CD25+ regulatory T cells suppress mast cell degranulation and allergic responses through OX40-OX40L interaction.

CXCL12 Mediates Aberrant Costimulation of B Lymphocytes in Warts, Hypogammaglobulinemia, Infections, Myelokathexis Immunodeficiency.

CXCR4 signaling in health and disease

Cbl-b mediates TGFβ sensitivity by downregulating inhibitory SMAD7 in primary T cells.

Chemokine nitration prevents intratumoral infiltration of antigen-specific T cells.

Constitutively active Lck kinase in T cells drives antigen receptor signal transduction

Differential involvement of α4β2, α7 and α9α10 nicotinic acetylcholine receptors in B lymphocyte activation in vitro

Extracellular Vesicles Secreted by Mesenchymal Stromal Cells Exert Opposite Effects to Their Cells of Origin in Murine Sodium Dextran Sulfate-Induced Colitis

From TCR Engagement to T Cell Activation

From tango to quadrilla: current views of the immunological synapse.

GM-CSF Nitration Is a New Driver of Myeloid Suppressor Cell Activity in Tumors

Human Immunodeficiencies Related to Defective APC/T Cell Interaction

Hypoxia-mediated regulation of macrophage functions in pathophysiology

IL1β Promotes TMPRSS2 Expression and SARS-CoV-2 Cell Entry Through the p38 MAPK-GATA2 Axis

Identification of a novel agrin-dependent pathway in cell signaling and adhesion within the erythroid niche

Innate immunity ascertained from blood and tracheal aspirates of preterm newborn provides new clues for assessing bronchopulmonary dysplasia

Intercellular Calcium Signaling Induced by ATP Potentiates Macrophage Phagocytosis

Lipid rafts in lymphocyte activation.

Membrane Rafts in T Cell Activation: A Spotlight on CD28 Costimulation

Mesenchymal stem cells: myths and reality

Metabolic mechanisms of cancer-induced inhibition of immune responses.

Modulation of human T-cell functions by reactive nitrogen species

Mouse mesenchymal stem cells inhibit high endothelial cell activation and lymphocyte homing to lymph nodes by releasing TIMP-1.

Orchestration of lymphocyte chemotaxis by mitochondrial dynamics

Phosphatidylinositol 4-Phosphate 5-Kinase β Controls Recruitment of Lipid Rafts into the Immunological Synapse

Phosphatidylinositol 4-Phosphate 5-Kinases in the Regulation of T Cell Activation

Phosphatidylinositol 4-phosphate 5-kinase α and Vav1 mutual cooperation in CD28-mediated actin remodeling and signaling functions

Physiological T cell activation starts and propagates in lipid rafts.

Prostate cancer-induced immunodysfunction: a lesson from organ cultures

Proteomic analysis of the secretome of human bone marrow-derived mesenchymal stem cells primed by pro-inflammatory cytokines

Regulatory T cells target chemokine secretion by dendritic cells independently of their capacity to regulate T cell proliferation

Self-antigen presentation by mouse B cells results in regulatory T-cell induction rather than anergy or clonal deletion

Smoothing T cell roads to the tumor: Chemokine post-translational regulation.

T Cells and Cancer: How Metabolism Shapes Immunity

T cell activation determined by T cell receptor number and tunable thresholds.

T cell costimulation by chemokine receptors

T cells and their partners: The chemokine dating agency.

T lymphocyte costimulation mediated by reorganization of membrane microdomains

T-cell activation and the dynamic world of rafts

Tether and trap: regulation of membrane-raft dynamics by actin-binding proteins.

The Kinase PKCα Selectively Upregulates Interleukin-17A during Th17 Cell Immune Responses ⬇️

The Metabolic Signature of Macrophage Responses

The critical role of agrin in the hematopoietic stem cell niche.

The pros and cons of chemokines in tumor immunology.

The raft marker GM1 identifies functional subsets of granular lymphocytes in patients with CD3+ lymphoproliferative disease of granular lymphocytes

Tunable chemokine production by antigen presenting dendritic cells in response to changes in regulatory T cell frequency in mouse reactive lymph nodes.

Tuning cancer fate: the unremitting role of host immunity.