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List of works by Lieve Moons

A freely available semi-automated method for quantifying retinal ganglion cells in entire retinal flatmounts

scientific article

A genetic Xenopus laevis tadpole model to study lymphangiogenesis

scientific article

A multidisciplinary approach unravels early and persistent effects of X-ray exposure at the onset of prenatal neurogenesis

scientific article

A novel retinal ganglion cell quantification tool based on deep learning

scientific article published on 12 January 2021

A proteomic approach to understand MMP-3-driven developmental processes in the postnatal cerebellum: Chaperonin CCT6A and MAP kinase as contributing factors.

scientific article published on 4 February 2015

AMA0076, a novel, locally acting Rho kinase inhibitor, potently lowers intraocular pressure in New Zealand white rabbits with minimal hyperemia.

scientific article

Aberrant Collagen Composition of the Trabecular Meshwork Results in Reduced Aqueous Humor Drainage and Elevated IOP in MMP-9 Null Mice

scientific article

Abnormal blood vessel development and lethality in embryos lacking a single VEGF allele

scientific article (publication date: 4 April 1996)

Abnormal retinal pigment epithelium melanogenesis as a major determinant for radiation-induced congenital eye defects

scientific article published on 06 November 2019

Abrupt rate accelerations or premature beats cause life-threatening arrhythmias in mice with long-QT3 syndrome.

scientific article

Altered neuronal architecture and plasticity in the visual cortex of adult MMP-3-deficient mice.

scientific article published on 25 June 2014

Amyloid β Oligomers Disrupt Blood-CSF Barrier Integrity by Activating Matrix Metalloproteinases.

scientific article published on September 2015

An Antagonistic Axon-Dendrite Interplay Enables Efficient Neuronal Repair in the Adult Zebrafish Central Nervous System

scientific article published on 13 August 2018

An aberrant cerebellar development in mice lacking matrix metalloproteinase-3.

scientific article published on 23 November 2011

Anatomical distribution of galanin-like immunoreactivity in the brain and pituitary of teleost fishes ⬇️

scientific article published on March 26, 1990

Another angiogenesis-independent role for VEGF: SDF1-dependent cardiac repair via cardiac stem cells

scientific article published on 23 June 2011

Anti-PlGF inhibits growth of VEGF(R)-inhibitor-resistant tumors without affecting healthy vessels

scientific article

Antibiotics may impair hematopoietic recovery after cytotoxic myeloablation

Arteriolar and venular patterning in retinas of mice selectively expressing VEGF isoforms

scientific article

Automated analysis of neurite outgrowth in mouse retinal explants.

scientific article published on 27 December 2012

Autoradiographic localization of binding sites for vasotocin in the brain and pituitary of the sea bass (Dicentrarchus labrax)

scientific article published on 01 May 1989

Bevacizumab revisited: its use in different mouse models of ocular pathologies

scientific article

Characterizing microglia activation: a spatial statistics approach to maximize information extraction

scientific article published on 8 May 2017

Chronic Chemogenetic Activation of the Superior Colliculus in Glaucomatous Mice: Local and Retrograde Molecular Signature

scientific article published on 29 May 2022

Coexistence of corticotropin-releasing factor-like immunoreactivity and vasotocin in perikarya of the preoptic nucleus in the eel.

scientific article published in April 1988

Combination of snapshot hyperspectral retinal imaging and optical coherence tomography to identify Alzheimer's disease patients

scientific article published on 10 November 2020

Comparative distribution of neuropeptide-immunoreactive systems in the brain of the green molly, Poecilia latipinna.

scientific article published in December 1990

Comparative distribution of substance P (SP) and cholecystokinin (CCK) binding sites and immunoreactivity in the brain of the sea bass (Dicentrarchus labrax)

scientific article published on January 1, 1992

Complementary effects of bevacizumab and MMC in the improvement of surgical outcome after glaucoma filtration surgery.

scientific article published on 18 May 2015

Complementary research in mammals and fish indicates MMP-2 as a pleiotropic contributor to optic nerve regeneration.

scientific article published on May 2016

Decreased TNF Levels and Improved Retinal Ganglion Cell Survival in MMP-2 Null Mice Suggest a Role for MMP-2 as TNF Sheddase

scientific article published on 15 September 2015

Decreased thyroid hormone signaling accelerates the reinnervation of the optic tectum following optic nerve crush in adult zebrafish.

scientific article published on 22 April 2015

Deficiency or inhibition of oxygen sensor Phd1 induces hypoxia tolerance by reprogramming basal metabolism

scientific article

Deletion of the hypoxia-response element in the vascular endothelial growth factor promoter causes motor neuron degeneration.

scientific article published in June 2001

Dendritic cell subsets differentially regulate angiogenesis in human ovarian cancer

scientific article published on 01 August 2004

Determination of serotonin, catecholamines and their metabolites by direct injection of supernatants from chicken brain tissue homogenate using liquid chromatography with electrochemical detection.

scientific article published in December 1997

Differential visual system organization and susceptibility to experimental models of optic neuropathies in three commonly used mouse strains

scientific article published on 11 January 2016

Distribution of beta-endorphin-like-immunoreactive structures in the chicken and quail brain as demonstrated with a new homologous antibody directed against a synthetic peptide

scientific article published on 01 December 1994

Downregulation of vascular endothelial-cadherin expression is associated with an increase in vascular tumor growth and hemorrhagic complications

scientific article published on 01 June 2005

Early Intervention and Lifelong Treatment with GLP1 Receptor Agonist Liraglutide in a Wolfram Syndrome Rat Model with an Emphasis on Visual Neurodegeneration, Sensorineural Hearing Loss and Diabetic Phenotype

scientific article published in 2021

Effects of Disruption of The Plasminogen Gene on Thrombosis, Growth, and Health in Mice ⬇️

scientific article published on November 1, 1995

Effects of vascular endothelial growth factor (VEGF) on motor neuron degeneration

scientific article published on 01 October 2004

Extensive growth is followed by neurodegenerative pathology in the continuously expanding adult zebrafish retina

scientific article published on 31 October 2018

Factor VII deficiency rescues the intrauterine lethality in mice associated with a tissue factor pathway inhibitor deficit

scientific article

Fibrinolysis-independent role of plasmin and its activators in the haematopoietic recovery after myeloablation

scientific article published on 22 November 2008

Function of the Plasminogen/Plasmin and Matrix Metalloproteinase Systems After Vascular Injury in Mice With Targeted Inactivation of Fibrinolytic System Genes ⬇️

scientific article published on July 1, 1998

Gas6 promotes inflammation by enhancing interactions between endothelial cells, platelets, and leukocytes.

scientific article published on 21 December 2007

Genetic deletion of placenta growth factor in mice alters uterine NK cells

scientific article

Genetic evidence for a tumor suppressor role of HIF-2alpha.

scientific article published in August 2005

Genetic loss of Gas6 induces plaque stability in experimental atherosclerosis

scientific article published on 01 September 2008

Genetic specification of left-right asymmetry in the diaphragm muscles and their motor innervation

scientific article

Identification of MMP-2 as a novel enhancer of cerebellar granule cell proliferation

scientific article published on 17 October 2013

Immunoaffinity purification and partial characterization of sea bass (Dicentrarchus labrax) growth hormone.

scientific article published in August 1991

Immunocytochemical demonstration of close relationships between neuropeptidergic nerve fibers and hormone-producing cell types in the adenohypophysis of the sea bass (Dicentrarchus labrax)

scientific article published on 01 February 1989

Immunolocalization of catecholamine enzymes, serotonin, dopamine and L-dopa in the brain of Dicentrarchus labrax (Teleostei).

scientific article published in January 1993

Impaired myocardial angiogenesis and ischemic cardiomyopathy in mice lacking the vascular endothelial growth factor isoforms VEGF164 and VEGF188

scientific journal article

Improving patient outcomes following glaucoma surgery: state of the art and future perspectives.

scientific article published on 02 May 2014

Inactivation of Smad5 in endothelial cells and smooth muscle cells demonstrates that Smad5 is required for cardiac homeostasis

scientific journal article

Inactivation of the gene for anticoagulant protein C causes lethal perinatal consumptive coagulopathy in mice

scientific article

Inhibition of Rho-Associated Kinase Prevents Pathological Wound Healing and Neovascularization After Corneal Trauma

scientific article published in September 2015

Inhibition of placental growth factor improves surgical outcome of glaucoma surgery.

scientific article published on 09 October 2013

Inhibition of plasminogen activators or matrix metalloproteinases prevents cardiac rupture but impairs therapeutic angiogenesis and causes cardiac failure

scientific article published in October 1999

Inhibition of vascular endothelial growth factor reduces scar formation after glaucoma filtration surgery

scientific article

Inhibitory role of plasminogen activator inhibitor-1 in arterial wound healing and neointima formation: a gene targeting and gene transfer study in mice

scientific article

Insights in vessel development and vascular disorders using targeted inactivation and transfer of vascular endothelial growth factor, the tissue factor receptor, and the plasminogen system.

scientific article published on April 1997

Intracameral bevacizumab as an adjunct to trabeculectomy: a 1-year prospective, randomised study.

scientific article published on 24 October 2013

Involvement of placental growth factor in Wallerian degeneration

scientific article

Lack of endothelial cell survivin causes embryonic defects in angiogenesis, cardiogenesis, and neural tube closure

scientific article published on 13 February 2007

Lack of plasminogen activator inhibitor-1 promotes growth and abnormal matrix remodeling of advanced atherosclerotic plaques in apolipoprotein E-deficient mice.

scientific article published in March 2002

Lentiviral vectors containing the human immunodeficiency virus type-1 central polypurine tract can efficiently transduce nondividing hepatocytes and antigen-presenting cells in vivo

scientific article published in August 2002

Life-threatening thrombosis in mice with targeted Arg48-to-Cys mutation of the heparin-binding domain of antithrombin.

scientific article published on 30 October 2003

Localization of growth hormone releasing factor-like immunoreactivity in the hypothalamo-hypophyseal system of the frog (Rana temporaria) and the sea bass (Dicentrarchus labrax)

scientific article published on 01 October 1988

Loss of HIF-2alpha and inhibition of VEGF impair fetal lung maturation, whereas treatment with VEGF prevents fatal respiratory distress in premature mice

scientific journal article

Loss of matrix metalloproteinase-9 or matrix metalloproteinase-12 protects apolipoprotein E-deficient mice against atherosclerotic media destruction but differentially affects plaque growth

scientific article published in March 2004

Loss of placental growth factor protects mice against vascular permeability in pathological conditions

scientific article

Loss of the VEGF(164) and VEGF(188) isoforms impairs postnatal glomerular angiogenesis and renal arteriogenesis in mice

scientific article published in June 2002

Loss of the cholesterol-binding protein prominin-1/CD133 causes disk dysmorphogenesis and photoreceptor degeneration

scientific journal article

Loss or inhibition of uPA or MMP-9 attenuates LV remodeling and dysfunction after acute pressure overload in mice

scientific article published on January 2005

MMP-2 mediates Purkinje cell morphogenesis and spine development in the mouse cerebellum

scientific article published on 21 March 2014

MMP-3 Deficiency Alleviates Endotoxin-Induced Acute Inflammation in the Posterior Eye Segment

scientific article

MMPs in the neuroretina and optic nerve: modulators of glaucoma pathogenesis and repair?

scientific article published on 28 March 2014

MMPs in the trabecular meshwork: promising targets for future glaucoma therapies?

scientific article

Matrix Metalloproteinases During Axonal Regeneration, a Multifactorial Role from Start to Finish

scientific article published on 29 February 2016

Matrix metalloproteinase 14 in the zebrafish: an eye on retinal and retinotectal development

scientific article

Matrix metalloproteinase 2 and membrane type 1 matrix metalloproteinase co-regulate axonal outgrowth of mouse retinal ganglion cells.

scientific article published on 27 March 2014

Matrix metalloproteinase-2 and -9 as promising benefactors in development, plasticity and repair of the nervous system

scientific article published on 06 April 2013

Matrix metalloproteinase-2 governs lymphatic vessel formation as an interstitial collagenase

scientific article

Matrix metalloproteinase-3 in the central nervous system: a look on the bright side.

scientific article published on 03 September 2012

Matrix metalloproteinases as promising regulators of axonal regrowth in the injured adult zebrafish retinotectal system.

scientific article published on 28 October 2015

Matrix metalloproteinases in the mouse retina: a comparative study of expression patterns and MMP antibodies

scientific article published on 29 December 2015

Matrix-binding vascular endothelial growth factor (VEGF) isoforms guide granule cell migration in the cerebellum via VEGF receptor Flk1

scientific article published on 01 November 2010

Mechanisms of NMDA Receptor- and Voltage-Gated L-Type Calcium Channel-Dependent Hippocampal LTP Critically Rely on Proteolysis That Is Mediated by Distinct Metalloproteinases.

scientific article published on 9 January 2017

Membrane-anchored uPAR regulates the proliferation, marrow pool size, engraftment, and mobilization of mouse hematopoietic stem/progenitor cells.

scientific article

Mice lacking factor VII develop normally but suffer fatal perinatal bleeding

scientific journal article

Microplasmin as an antiscarring agent for glaucoma surgery: translation into clinical application

scientific article published on 01 January 2011

Mitochondrial dysfunction underlying outer retinal diseases.

scientific article published on 29 March 2017

Mitochondrial function in Müller cells - Does it matter?

scientific article published on 5 February 2017

Modulation of wound healing in glaucoma surgery

scientific article

Mouse models of angiogenesis, arterial stenosis, atherosclerosis and hemostasis ⬇️

scientific article published on July 1, 1998

Myocardial hypertrophy in the absence of external stimuli is induced by angiogenesis in mice

scientific article

Neuroinflammation as Fuel for Axonal Regeneration in the Injured Vertebrate Central Nervous System.

scientific article published on 19 January 2017

Noradrenergic system in the chicken brain: immunocytochemical study with antibodies to noradrenaline and dopamine-beta-hydroxylase

scientific article published on 01 September 1995

Notch3 Arg170Cys knock-in mice display pathologic and clinical features of the neurovascular disorder cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy.

scientific article

Novel transgenic rabbit model sheds light on the puzzling role of matrix metalloproteinase-12 in atherosclerosis

scientific article published on 01 April 2006

Ocular hypertension results in retinotopic alterations in the visual cortex of adult mice.

scientific article published on 23 January 2015

Oxygen-induced retinopathy in mice: amplification by neonatal IGF-I deficit and attenuation by IGF-I administration

scientific article

Peroxisomal Multifunctional Protein 2 Deficiency Perturbs Lipid Homeostasis in the Retina and Causes Visual Dysfunction in Mice

scientific article published on 02 February 2021

Persistent Impact of In utero Irradiation on Mouse Brain Structure and Function Characterized by MR Imaging and Behavioral Analysis.

scientific article

Placental growth factor promotes atherosclerotic intimal thickening and macrophage accumulation

scientific article

Platelet-Associated Matrix Metalloproteinases Regulate Thrombus Formation and Exert Local Collagenolytic Activity.

scientific article published on 15 October 2015

Pleiotropic role of growth arrest-specific gene 6 in atherosclerosis.

scientific article published on October 2009

Prior Exposure to Immunosuppressors Sensitizes Retinal Microglia and Accelerates Optic Nerve Regeneration in Zebrafish

scientific article published on 10 February 2019

Protective Role of Reactive Astrocytes in Brain Ischemia

scientific article published on 29 August 2007

Quantitative Assessment of Neurite Outgrowth in Mouse Retinal Explants

scientific article published on 01 January 2014

ROCK inhibition as a novel potential strategy for axonal regeneration in optic neuropathies

scientific article published on December 2015

Receptor-independent Role of Urokinase-Type Plasminogen Activator in Pericellular Plasmin and Matrix Metalloproteinase Proteolysis during Vascular Wound Healing in Mice ⬇️

scientific article published on January 12, 1998

Receptors for Cor ticotropin-Releasing Hormone in Human Pituitary: Binding Characteristics and Autoradiographic Localization to Immunocytochemically Defined Proopiomelanocortin Cells ⬇️

scientific article published on August 1, 1991

Reevaluation of the role of VEGF-B suggests a restricted role in the revascularization of the ischemic myocardium

scientific article published on 29 May 2008

Resistance to retinopathy development in obese, diabetic and hypertensive ZSF1 rats: an exciting model to identify protective genes

scientific article published in Scientific Reports

Revascularization of ischemic tissues by PDGF-CC via effects on endothelial cells and their progenitors

scientific article published on January 2005

Revascularization of ischemic tissues by PlGF treatment, and inhibition of tumor angiogenesis, arthritis and atherosclerosis by anti-Flt1.

scientific article

Rho kinase inhibitor AMA0526 improves surgical outcome in a rabbit model of glaucoma filtration surgery.

scientific article

Role of HIF-1alpha in hypoxia-mediated apoptosis, cell proliferation and tumour angiogenesis

scientific article

Role of PlGF in the intra- and intermolecular cross talk between the VEGF receptors Flt1 and Flk1

scientific article

Role of VEGF-D and VEGFR-3 in developmental lymphangiogenesis, a chemicogenetic study in Xenopus tadpoles.

scientific article

Role of placental growth factor (PLGF) in wound healing after glaucoma filtration surgery

scientific article published on 01 January 2011

Role of tissue factor in embryonic blood vessel development.

scientific article

Serotype-dependent transduction efficiencies of recombinant adeno-associated viral vectors in monkey neocortex

scientific article published on July 2015

Short-term delivery of anti-PlGF antibody delays progression of atherosclerotic plaques to vulnerable lesions

scientific article published on 01 December 2009

Synergism between vascular endothelial growth factor and placental growth factor contributes to angiogenesis and plasma extravasation in pathological conditions.

scientific article published in May 2001

Synthesis and Validation of a Hydroxypyrone-Based, Potent, and Specific Matrix Metalloproteinase-12 Inhibitor with Anti-Inflammatory Activity In Vitro and In Vivo.

scientific article

Tackling Glaucoma from within the Brain: An Unfortunate Interplay of BDNF and TrkB

scientific article published on 11 November 2015

Target-Derived Neurotrophic Factor Deprivation Puts Retinal Ganglion Cells on Death Row: Cold Hard Evidence and Caveats ⬇️

scientific article published on 03 September 2019

Targeted deficiency or cytosolic truncation of the VE-cadherin gene in mice impairs VEGF-mediated endothelial survival and angiogenesis

scientific article (publication date: 23 July 1999)

Targeted deletion of the cytosolic domain of tissue factor in mice does not affect development

scientific journal article

The Combination of PlGF Inhibition and MMC as a Novel Anti-Scarring Strategy for Glaucoma Filtration Surgery

scientific article published on August 2016

The Role of LOX and LOXL2 in the Pathogenesis of an Experimental Model of Choroidal Neovascularization.

scientific article published on August 2015

The effect of AMA0428, a novel and potent ROCK inhibitor, in a model of neovascular age-related macular degeneration.

scientific article published on 27 January 2015

The nuclear scaffold protein NIPP1 is essential for early embryonic development and cell proliferation

scientific journal article

The role of LOX and LOXL2 in scar formation after glaucoma surgery.

scientific article published on 27 August 2013

The role of different VEGF isoforms in scar formation after glaucoma filtration surgery.

scientific article published in September 2011

The role of fatty acid β-oxidation in lymphangiogenesis

scientific article published on 26 December 2016

The role of placental growth factor (PlGF) and its receptor system in retinal vascular diseases

scientific article published on 30 October 2018

The role of the VEGF-isoforms in pathological choroidal/retinal angiogenesis

scientific article published on 01 January 2011

The zebrafish as a gerontology model in nervous system aging, disease, and repair

scientific article published on 29 October 2015

Thrombophilia in mice expressing a tissue factor variant lacking its transmembrane and cytosolic domain

scientific article

Tightening the retinal glia limitans attenuates neuroinflammation after optic nerve injury

scientific article published on 09 July 2020

Towards axonal regeneration and neuroprotection in glaucoma: Rho kinase inhibitors as promising therapeutics.

scientific article published on 17 June 2015

Toxicology studies with recombinant staphylokinase and with SY 161-P5, a polyethylene glycol-derivatized cysteine-substitution mutant.

scientific article published in May 2001

Treatment of motoneuron degeneration by intracerebroventricular delivery of VEGF in a rat model of ALS.

scientific article

Urokinase but Not Tissue Plasminogen Activator Mediates Arterial Neointima Formation in Mice ⬇️

scientific article published on November 1, 1997

Urokinase-generated plasmin activates matrix metalloproteinases during aneurysm formation ⬇️

scientific article published on December 1, 1997

VEGF is a modifier of amyotrophic lateral sclerosis in mice and humans and protects motoneurons against ischemic death

scientific article published in August 2003

VEGF-D deficiency in mice does not affect embryonic or postnatal lymphangiogenesis but reduces lymphatic metastasis.

scientific article published in November 2009

VEGF: a modifier of the del22q11 (DiGeorge) syndrome?

scientific article published on 21 January 2003

gamma-Secretase heterogeneity in the Aph1 subunit: relevance for Alzheimer's disease

scientific article

αB-Crystallin regulates expansion of CD11b⁺Gr-1⁺ immature myeloid cells during tumor progression.

scientific article

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