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List of works by Mark Hampton

A functional NADPH oxidase prevents caspase involvement in the clearance of phagocytic neutrophils

scientific article published on 16 April 2007

A single assay for measuring the rates of phagocytosis and bacterial killing by neutrophils.

scientific article

Accumulation of oxidized peroxiredoxin 2 in red blood cells and its prevention.

scientific article published on 26 February 2015

Activation of NF-kappaB in human neutrophils during phagocytosis of bacteria independently of oxidant generation.

scientific article published on July 1998

Analysis of Neutrophil Bactericidal Activity

scientific article published on 01 January 2020

Analysis of neutrophil bactericidal activity

scientific article

Analysis of neutrophil bactericidal activity

scientific article published on 01 January 2014

Assessment of redox changes to hydrogen peroxide-sensitive proteins during EGF signaling.

scientific article published on 18 April 2011

Bacterial killing by neutrophils in hypertonic environments.

scientific article

Bcl-2 over-expression promotes genomic instability by inhibiting apoptosis of cells exposed to hydrogen peroxide.

scientific article published on 13 April 2007

Biological targets of isothiocyanates ⬇️

scientific article published on June 17, 2011

Caspase involvement in the induction of apoptosis by the environmental toxicants tributyltin and triphenyltin

scientific article published on 01 April 1999

Chlorination of bacterial and neutrophil proteins during phagocytosis and killing of Staphylococcus aureus

scientific article published on 3 December 2001

Cryo-electron microscopy structure of human peroxiredoxin-3 filament reveals the assembly of a putative chaperone.

scientific article published on 23 April 2015

Cytochrome c release and caspase activation in hydrogen peroxide- and tributyltin-induced apoptosis

scientific article published in June 1998

Detection of apoptosis by caspase-3 activation in tracheal aspirate neutrophils from premature infants: relationship with NF-kappaB activation

scientific article published on 16 December 2004

Detection of oxidant sensitive thiol proteins by fluorescence labeling and two-dimensional electrophoresis

scientific article published in September 2002

Diphenyleneiodonium triggers the efflux of glutathione from cultured cells.

scientific article published on 19 March 2002

Direct cardiac actions of erythropoietin (EPO): effects on cardiac contractility, BNP secretion and ischaemia/reperfusion injury

scientific journal article

Direct modification of the proinflammatory cytokine macrophage migration inhibitory factor by dietary isothiocyanates

scientific article published on 23 September 2009

Dual regulation of caspase activity by hydrogen peroxide: implications for apoptosis ⬇️

scientific article published on September 15, 1997

Effect of activated human polymorphonuclear leucocytes on T lymphocyte proliferation and viability

scientific article published in November 2012

Embryonic oxidative stress results in reproductive impairment for adult zebrafish.

scientific article

Evaluating the bactericidal action of hypochlorous acid in culture media

scientific article published on 30 July 2020

Exposure of Pseudomonas aeruginosa to bactericidal hypochlorous acid during neutrophil phagocytosis is compromised in cystic fibrosis

scientific article published on 24 July 2019

Formulation of Broccoli Sprout Powder in Gastro-Resistant Capsules Protects against the Acidic pH of the Stomach In Vitro but Does Not Increase Isothiocyanate Bioavailability In Vivo

scientific article published on 01 September 2019

Frailty in surgical patients

scientific article published on 14 September 2018

Genome-wide impact of hydrogen peroxide on maintenance DNA methylation in replicating cells

scientific article published on 24 March 2021

Helicobacter pylori outer membrane vesicles modulate proliferation and interleukin-8 production by gastric epithelial cells

scientific article

Hyperoxidation of peroxiredoxins 2 and 3: rate constants for the reactions of the sulfenic acid of the peroxidatic cysteine

scientific article published on 29 March 2013

Hyperoxidized peroxiredoxin 2 interacts with the protein disulfide- isomerase ERp46.

scientific article published in August 2013

Hypochlorous acid causes caspase activation and apoptosis or growth arrest in human endothelial cells

scientific article published in December 1999

Importance of the redox state of cytochrome c during caspase activation in cytosolic extracts ⬇️

scientific article published on January 1, 1998

Inactivation of cellular caspases by peptide-derived tryptophan and tyrosine peroxides

scientific article published in September 2002

Individual and combined effects of foods on Helicobacter pylori growth

scientific article published on 01 August 2010

Induction of apoptosis by phenethyl isothiocyanate in cells overexpressing Bcl-XL.

scientific article published on 18 July 2008

Induction of the reactive chlorine-responsive transcription factor RclR in Escherichia coli following ingestion by neutrophils

scientific article published on 22 December 2020

Inhibition of DNA methylation in proliferating human lymphoma cells by immune cell oxidants

scientific article published on 20 April 2020

Inhibition of myeloperoxidase by benzoic acid hydrazides

scientific article

Inhibition of receptor-mediated apoptosis upon Bcl-2 overexpression is not associated with increased antioxidant status.

scientific article published on 5 August 2008

Inside the neutrophil phagosome: oxidants, myeloperoxidase, and bacterial killing.

scientific article

Interaction with substrate sensitises caspase-3 to inactivation by hydrogen peroxide.

scientific article

Interactions between peroxiredoxin 2, hemichrome and the erythrocyte membrane

scientific article published on 28 September 2016

Introduction to Special Issue on Mitochondrial Redox Signaling in Health and Disease

scientific article published on 5 August 2016

Involvement of superoxide and myeloperoxidase in oxygen-dependent killing of Staphylococcus aureus by neutrophils

scientific article

Kinetic analysis of structural influences on the susceptibility of peroxiredoxins 2 and 3 to hyperoxidation

scientific article published on 27 November 2015

Macrophage migration inhibitory factor (MIF) is rendered enzymatically inactive by myeloperoxidase-derived oxidants but retains its immunomodulatory function

scientific article published on 7 October 2015

Macrophage migration inhibitory factor covalently complexed with phenethyl isothiocyanate

scientific article

Macrophage migration inhibitory factor gene polymorphisms in inflammatory bowel disease: an association study in New Zealand Caucasians and meta-analysis

scientific article published on October 2013

Maternal undernutrition significantly impacts ovarian follicle number and increases ovarian oxidative stress in adult rat offspring

scientific article

Measuring mitochondrial protein thiol redox state

scientific article published on 20 June 2010

Measuring the redox state of cellular peroxiredoxins by immunoblotting

scientific article published on 20 June 2010

Methods for quantifying phagocytosis and bacterial killing by human neutrophils

scientific article

Mitochondria as the focus of apoptosis research

scientific article published on 01 August 1997

Mitochondria: unravelling the secrets of life and death

scientific article published on 01 January 1999

Mitochondrial peroxiredoxin 3 is more resilient to hyperoxidation than cytoplasmic peroxiredoxins.

scientific article published on 12 June 2009

Mitochondrial peroxiredoxin 3 is rapidly oxidized in cells treated with isothiocyanates.

scientific article published on 29 April 2008

Mitochondrial peroxiredoxin involvement in antioxidant defence and redox signalling

scientific article published on 23 December 2009

Mitochondrial respiratory chain involvement in peroxiredoxin 3 oxidation by phenethyl isothiocyanate and auranofin.

scientific article published on 19 February 2010

Model for the exceptional reactivity of peroxiredoxins 2 and 3 with hydrogen peroxide: a kinetic and computational study

scientific journal article

Modeling the reactions of superoxide and myeloperoxidase in the neutrophil phagosome: implications for microbial killing

scientific article published on 30 October 2006

Modification of neutrophil oxidant production with diphenyleneiodonium and its effect on bacterial killing

scientific article published on 01 April 1995

Multiple binding modes of isothiocyanates that inhibit macrophage migration inhibitory factor

scientific article

Myeloperoxidase-dependent lipid peroxidation promotes the oxidative modification of cytosolic proteins in phagocytic neutrophils

scientific article

NADPH oxidase involvement in the pathology of Helicobacter pylori infection

scientific article

Neutrophil-mediated oxidation of erythrocyte peroxiredoxin 2 as a potential marker of oxidative stress in inflammation.

scientific article published on 19 April 2013

Neutrophil-vascular interactions drive myeloperoxidase accumulation in the brain in Alzheimer's disease

scientific article published on 24 March 2022

Outer membrane vesicles enhance the carcinogenic potential of Helicobacter pylori

scientific article published on 10 September 2008

OxLDL induced cell death is inhibited by the macrophage synthesised pterin, 7,8-dihydroneopterin, in U937 cells but not THP-1 cells.

scientific article published in September 2005

Oxidant-mediated phosphatidylserine exposure and macrophage uptake of activated neutrophils: possible impairment in chronic granulomatous disease.

scientific article

Oxidation of calprotectin by hypochlorous acid prevents chelation of essential metal ions and allows bacterial growth: Relevance to infections in cystic fibrosis

scientific article

Oxidation of mitochondrial peroxiredoxin 3 during the initiation of receptor-mediated apoptosis

scientific article published on 5 December 2007

Oxidized LDL triggers phosphatidylserine exposure in human monocyte cell lines by both caspase-dependent and -independent mechanisms.

scientific article

Peroxiredoxin 2 and peroxide metabolism in the erythrocyte.

scientific article published on September 2008

Peroxiredoxin 2 functions as a noncatalytic scavenger of low-level hydrogen peroxide in the erythrocyte

scientific article published on 14 November 2006

Peroxiredoxin expression and redox status in neutrophils and HL-60 cells

scientific article published on 09 March 2019

Peroxiredoxin interaction with the cytoskeletal-regulatory protein CRMP2: Investigation of a putative redox relay

scientific article published on 10 October 2018

Peroxiredoxin involvement in the initiation and progression of human cancer.

scientific article published on 14 December 2017

Peroxiredoxins and the Regulation of Cell Death

scientific article

Peroxiredoxins as biomarkers of oxidative stress.

scientific article published on 09 August 2013

Peroxiredoxins in Colorectal Cancer: Predictive Biomarkers of Radiation Response and Therapeutic Targets to Increase Radiation Sensitivity?

scientific article published on 5 October 2018

Phenethyl isothiocyanate triggers apoptosis in Jurkat cells made resistant by the overexpression of Bcl-2.

scientific article published on July 2006

Post-translational regulation of macrophage migration inhibitory factor: Basis for functional fine-tuning.

scientific article published on 6 December 2017

Potent inhibition of macrophage migration inhibitory factor (MIF) by myeloperoxidase-dependent oxidation of epicatechins

scientific article published on 01 September 2014

Prolonged exposure to hypoxia induces an autophagy-like cell survival program in human neutrophils

scientific article published on 14 August 2019

Protein thiol oxidation and formation of S-glutathionylated cyclophilin A in cells exposed to chloramines and hypochlorous acid.

scientific article

Proteomic detection of hydrogen peroxide-sensitive thiol proteins in Jurkat cells

scientific article published in August 2005

Proteomic detection of oxidized and reduced thiol proteins in cultured cells

scientific article published in January 2009

Quantifying mitochondrial respiration in human lymphocytes and monocytes challenged with hydrogen peroxide

scientific article published on 24 April 2020

Quaternary structure influences the peroxidase activity of peroxiredoxin 3.

scientific article published on 10 February 2018

Reactions of superoxide with myeloperoxidase

scientific article published on 24 March 2007

Reactive Oxygen Species and Neutrophil Function

scientific article published on 6 April 2016

Redox biology: signaling via a peroxiredoxin sensor

scientific article published on 17 December 2014

Redox potential and peroxide reactivity of human peroxiredoxin 3.

scientific article

Redox proteomics of thiol proteins in mouse heart during ischemia/reperfusion using ICAT reagents and mass spectrometry

scientific article published on 29 January 2013

Redox regulation of apoptotic cell death ⬇️

scientific article published on January 1, 1998

Redox regulation of neutrophil function

scientific article published in February 2002

Redox regulation of the caspases during apoptosis

scientific article published on 01 November 1998

Regulation of apoptosis by vitamin C. Specific protection of the apoptotic machinery against exposure to chlorinated oxidants.

scientific article

Removal of amino acid, peptide and protein hydroperoxides by reaction with peroxiredoxins 2 and 3.

scientific article published on December 2010

Requirements for NADPH oxidase and myeloperoxidase in neutrophil extracellular trap formation differ depending on the stimulus

scientific article published on 16 July 2012

Research on shaky ground

scientific article published on 01 January 2012

Reversible oxidation of mitochondrial peroxiredoxin 3 in mouse heart subjected to ischemia and reperfusion.

scientific article published on 21 February 2009

Structure-function analyses of alkylhydroperoxidase D from Streptococcus pneumoniae reveal an unusual three-cysteine active site architecture

scientific article published on 23 January 2020

Structures of Human Peroxiredoxin 3 Suggest Self-Chaperoning Assembly that Maintains Catalytic State

scientific article published on 6 July 2016

Telomere length measurement on the Roche LightCycler 480 Platform

scientific article published on 23 December 2014

The chemopreventive agent phenethyl isothiocyanate sensitizes cells to Fas-mediated apoptosis.

scientific article published on 16 January 2004

The high reactivity of peroxiredoxin 2 with H(2)O(2) is not reflected in its reaction with other oxidants and thiol reagents

scientific article published on 27 February 2007

The marine cytotoxin portimine is a potent and selective inducer of apoptosis

scientific article published on 13 October 2016

The role of oxidants and vitamin C on neutrophil apoptosis and clearance

scientific article published on June 2004

The thioredoxin reductase inhibitor auranofin triggers apoptosis through a Bax/Bak-dependent process that involves peroxiredoxin 3 oxidation

scientific article published on 26 August 2008

Thiol chemistry and specificity in redox signaling

scientific article (publication date: September 2008)

Thioredoxin reductase 1 and NADPH directly protect protein tyrosine phosphatase 1B from inactivation during H2O2 exposure

scientific article published on 6 July 2017

Uptake of Helicobacter pylori outer membrane vesicles by gastric epithelial cells.

scientific article published on 27 September 2010

Using food to reduce H. pylori-associated inflammation.

scientific article

Valproic acid exposure leads to upregulation and increased promoter histone acetylation of sepiapterin reductase in a serotonergic cell line

scientific article published on 4 July 2015

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