List of works by Toshihide Yamashita

A chromosome 16p13.11 microduplication causes hyperactivity through dysregulation of miR-484/protocadherin-19 signaling

scientific article published on 05 July 2016

A pain-mediated neural signal induces relapse in murine autoimmune encephalomyelitis, a multiple sclerosis model

scientific article

A proapoptotic effect of valproic acid on progenitors of embryonic stem cell-derived glutamatergic neurons.

scientific article published on 20 June 2013

A selector orchestrates cortical function

scientific article published in August 2014

Acetylation of NDPK-D Regulates Its Subcellular Localization and Cell Survival

scientific article

Activated microglia inhibit axonal growth through RGMa

scientific article (publication date: 2011)

Adenoviral gene transfer in the peripheral nervous system

article

An Image-Based miRNA screen identifies miRNA-135s as regulators of CNS axon growth and regeneration by targeting Krüppel-like factor 4.

scientific article published in December 2017

Angiogenesis induced by CNS inflammation promotes neuronal remodeling through vessel-derived prostacyclin

scientific article published on 07 October 2012

Anti-repulsive guidance molecule-a antibody treatment and repetitive transcranial magnetic stimulation have synergistic effects on motor recovery after spinal cord injury

scientific article published on 11 June 2019

Axon growth inhibition by RhoA/ROCK in the central nervous system

scientific article

Axonal remodeling for motor recovery after traumatic brain injury requires downregulation of γ-aminobutyric acid signaling.

scientific article

Axotomy induces axonogenesis in hippocampal neurons by a mechanism dependent on importin β

scientific article published on 01 February 2011

Axotomy induces axonogenesis in hippocampal neurons through STAT3.

scientific article published on 23 June 2011

B-1a lymphocytes promote oligodendrogenesis during brain development.

scientific article published on 5 March 2018

BMP inhibition enhances axonal growth and functional recovery after spinal cord injury

scientific article published on 24 January 2008

BMP inhibits neurite growth by a mechanism dependent on LIM-kinase

scientific article published on 10 July 2007

Bidirectional tuning of microglia in the developing brain: from neurogenesis to neural circuit formation

scientific article published on 05 March 2014

Binding of soluble myelin-associated glycoprotein to specific gangliosides induces the association of p75NTR to lipid rafts and signal transduction.

scientific article

Brimonidine promotes axon growth after optic nerve injury through Erk phosphorylation.

scientific article

Cardiomyocyte-released factors stimulate oligodendrocyte precursor cells proliferation.

scientific article published on 2 December 2016

Changes in glutamate/aspartate transporter (GLAST/GluT-1) mRNA expression following facial nerve transection

scientific article published on 01 June 1996

Changes in growth inhibitory factor mRNA expression compared with those in c-jun mRNA expression following facial nerve transection

scientific article published on 01 February 1995

Changes in mRNA for VAMPs following facial nerve transection

scientific article published on 01 July 2002

Changes in mRNA for choline transporter-like protein following facial nerve transection.

scientific article

Changes in mRNA of protein inhibitor of neuronal nitric oxide synthase following facial nerve transection

scientific article published on 01 January 2000

Characterizing the neurite outgrowth inhibitory effect of Mani

scientific article

Chimaerins act downstream from neurotrophins in overcoming the inhibition of neurite outgrowth produced by myelin-associated glycoprotein.

scientific article published in October 2004

Chondroitin sulfate proteoglycans down-regulate spine formation in cortical neurons by targeting tropomyosin-related kinase B (TrkB) protein

scientific article published on 2 March 2012

Chronic inflammatory demyelinating polyneuropathy sera inhibit axonal growth of mouse dorsal root ganglion neurons by activation of Rho-kinase.

scientific article

Class I histone deacetylase (HDAC) inhibitor CI-994 promotes functional recovery following spinal cord injury.

scientific article published on 27 April 2018

Cloning of a bovine orphan transporter and its short splicing variant.

scientific article

Comparison of gene expression profile of the spinal cord of sprouting-capable neonatal and sprouting-incapable adult mice

scientific article published on 30 July 2019

Concept and molecular basis of axonal regeneration after central nervous system injury

scientific article published on 26 July 2013

Corrigendum: Ecto-domain phosphorylation promotes functional recovery from spinal cord injury

scientific article published on July 2015

Corticospinal tract fibers cross the ephrin-B3-negative part of the midline of the spinal cord after brain injury

scientific article published on 13 December 2010

Cytoplasmic p21(Cip1/WAF1) enhances axonal regeneration and functional recovery after spinal cord injury in rats.

scientific article published in January 2004

Decreased cohesin in the brain leads to defective synapse development and anxiety-related behavior

scientific article

Delayed treatment with Rho-kinase inhibitor does not enhance axonal regeneration or functional recovery after spinal cord injury in rats

scientific article published on 19 April 2006

Deletion of JMJD2B in neurons leads to defective spine maturation, hyperactive behavior and memory deficits in mouse

scientific article

Developmental abnormality contributes to cortex-dependent motor impairments and higher intracortical current requirement in the reeler homozygous mutants.

scientific article published on 13 March 2018

Developmental regulation of FERM domain including guanine nucleotide exchange factor gene expression in the mouse brain.

scientific article published in September 2003

Developmental regulation of Na+ / myo-inositol cotransporter gene expression.

scientific article published in November 1997

Dorsal horn interneuron-derived Netrin-4 contributes to spinal sensitization in chronic pain via Unc5B.

scientific article

Down-regulation of KCC2 expression and phosphorylation in motoneurons, and increases the number of in primary afferent projections to motoneurons in mice with post-stroke spasticity

scientific article

Ecto-domain phosphorylation promotes functional recovery from spinal cord injury

scientific article

Endothelin promotes neurite elongation by a mechanism dependent on c-Jun N-terminal kinase.

scientific article published on 23 April 2009

Engulfment of axon debris by microglia requires p38 MAPK activity.

scientific article

EphA receptors direct the differentiation of mammalian neural precursor cells through a mitogen-activated protein kinase-dependent pathway

scientific journal article

Expression of FERM domain including guanine nucleotide exchange factor mRNA in adult rat brain.

scientific article published in June 2003

Expression of galectin-1 in immune cells and glial cells after spinal cord injury

scientific article published on 24 November 2009

Expression of growth inhibitory factor mRNA following cortical injury in rat

scientific article published on 01 June 1995

Expression of mitochondrial tricarboxylate carrier TCC mRNA and protein in the rat brain

scientific journal article

Expression of tPA mRNA in the facial nucleus following facial nerve transection in the rat

scientific article published on 01 January 1997

Extracellular signal-regulated kinase mitogen-activated protein kinase activation in the dorsal root ganglion (DRG) and spinal cord after DRG injury in rats

scientific article published on 01 October 2005

Function of Lymphocytes in Oligodendrocyte Development

scientific article published on 08 March 2019

Functional inhibition of the p75 receptor using a small interfering RNA.

scientific article published in February 2003

Genetic deletion of paired immunoglobulin-like receptor B does not promote axonal plasticity or functional recovery after traumatic brain injury

scientific article published on 01 September 2010

Glucocorticoid suppresses dendritic spine development mediated by down-regulation of caldesmon expression

scientific article published in October 2012

Identification and characterization of a novel mitochondrial tricarboxylate carrier

scientific journal article

Identification of the neogenin-binding site on the repulsive guidance molecule A

scientific article

Improvement in protocol to generate homogeneous glutamatergic neurons from mouse embryonic stem cells reduced apoptosis.

scientific article published on 5 December 2012

Inactivation of Ras by p120GAP via focal adhesion kinase dephosphorylation mediates RGMa-induced growth cone collapse.

scientific article

Increased Expression of Fibronectin Leucine-Rich Transmembrane Protein 3 in the Dorsal Root Ganglion Induces Neuropathic Pain in Rats

scientific article published on 25 July 2019

Increased transcription of glutamate-aspartate transporter (GLAST/GluT-1) mRNA following kainic acid-induced limbic seizure.

scientific article published in March 1998

Induction of aquaporin-4 water channel mRNA after focal cerebral ischemia in rat.

scientific article published in May 2000

Induction of mRNAs and proteins for Na/K ATPase alpha1 and beta1 subunits following hypoxia/reoxygenation in astrocytes

scientific journal article

Induction of repulsive guidance molecule in neurons following sciatic nerve injury

scientific article published on 24 July 2006

Inhibiting repulsive guidance molecule-a suppresses secondary progression in mouse models of multiple sclerosis

scholarly article by Shogo Tanabe et al published 17 October 2018 in Cell Death and Disease

Inhibition of HDAC increases BDNF expression and promotes neuronal rewiring and functional recovery after brain injury

scientific article published on 18 August 2020

Inhibition of TGF-beta1 promotes functional recovery after spinal cord injury

scientific article published on 08 September 2009

Inhibition of a eukaryotic initiation factor (eIF2Bdelta/F11A3.2) during adulthood extends lifespan in Caenorhabditis elegans

scientific article published on 26 August 2008

Inhibition of branching and spine maturation by repulsive guidance molecule in cultured cortical neurons.

scientific article published on 2 June 2008

Intraspinal rewiring of the corticospinal tract requires target-derived brain-derived neurotrophic factor and compensates lost function after brain injury.

scientific article published on 21 March 2012

Involvement of Wnt/β-catenin signaling in the development of neuropathic pain.

scientific article

Kainic acid-induced seizure upregulates Na(+)/myo-inositol cotransporter mRNA in rat brain.

scientific article

Keratan sulfate restricts neural plasticity after spinal cord injury

scientific article published on 01 November 2011

Kinematic analyses reveal impaired locomotion following injury of the motor cortex in mice

scientific article published on 13 May 2011

Layer V cortical neurons require microglial support for survival during postnatal development.

scientific article published on 24 March 2013

Leptin sustains spontaneous remyelination in the adult central nervous system.

scientific article published on 16 January 2017

Limited functional recovery in rats with complete spinal cord injury after transplantation of whole-layer olfactory mucosa: laboratory investigation.

scientific article published in February 2010

Loss and apoptosis of smooth muscle cells in intracranial aneurysms. Studies with in situ DNA end labeling and antibody against single-stranded DNA

scientific article published on 01 January 1997

Loss of p73 in ependymal cells during the perinatal period leads to aqueductal stenosis.

scientific article published on 20 September 2017

Lrig2 Negatively Regulates Ectodomain Shedding of Axon Guidance Receptors by ADAM Proteases

scientific journal article

Macrophage P2X4 receptors augment bacterial killing and protect against sepsis.

scientific article published on 7 June 2018

Messenger RNA and protein expression of basic fibroblast growth factor receptor after cortical ablation

scientific article published on 01 August 1994

Methylation dependent down-regulation of G0S2 leads to suppression of invasion and improved prognosis of IDH1-mutant glioma

scientific article published in PLoS ONE

Microglia in central nervous system repair after injury.

scientific article published on 08 February 2016

Microglia suppress the secondary progression of autoimmune encephalomyelitis

scientific article published on 20 May 2019

Multiple signals regulate axon regeneration through the Nogo receptor complex.

scientific article

Myosin IIA is required for neurite outgrowth inhibition produced by repulsive guidance molecule

scientific article published on 12 November 2007

N-acetylglucosamine 6-O-sulfotransferase-1-deficient mice show better functional recovery after spinal cord injury.

scientific article published in April 2010

NME2 associates with PTPσ to transduce signals from chondroitin sulfate proteoglycans.

scientific article published on 16 February 2016

Neogenin and repulsive guidance molecule signaling in the central nervous system.

scientific article published on 13 December 2006

Neogenin is a Determining Factor for Regenerating Neurons Following Spinal Cord Injury

scientific article published on 21 December 2018

Neogenin regulates neuronal survival through DAP kinase.

scientific article

Nerve growth factor of cultured medium extracted from human degenerative nucleus pulposus promotes sensory nerve growth and induces substance p in vitro

scientific article published in October 2009

Netrin-4 regulates thalamocortical axon branching in an activity-dependent fashion

scientific article

Neurons promote encephalitogenic CD4+ lymphocyte infiltration in experimental autoimmune encephalomyelitis

scientific article published on 30 April 2020

Neuropilin-1-mediated pruning of corticospinal tract fibers is required for motor recovery after spinal cord injury

Neuroprotective role of Na+/myo-inositol cotransporter against veratridine cytotoxicity

scientific article published on 01 May 1999

Neurotrophin binding to the p75 receptor modulates Rho activity and axonal outgrowth

scientific article published on 01 November 1999

Olfactory mucosal transplantation after spinal cord injury improves voiding efficiency by suppressing detrusor-sphincter dyssynergia in rats.

scientific article published on 19 June 2010

PKA phosphorylates the p75 receptor and regulates its localization to lipid rafts

scientific article

Paired immunoglobulin-like receptor B knockout does not enhance axonal regeneration or locomotor recovery after spinal cord injury.

scientific article published on 18 November 2010

Peptides derived from repulsive guidance molecule act as antagonists

scientific journal article

Pericyte function in the physiological central nervous system

scientific article published on 30 January 2014

Peripherally derived FGF21 promotes remyelination in the central nervous system

scientific article published on 21 August 2017

Progressive hearing loss in mice carrying a mutation in the p75 gene.

scientific article

Prolyl hydroxylase regulates axonal rewiring and motor recovery after traumatic brain injury.

scientific article published on 12 February 2015

Promotion of axon regeneration by myelin-associated glycoprotein and Nogo through divergent signals downstream of Gi/G

scientific journal article

Prostacyclin prevents pericyte loss and demyelination induced by lysophosphatidylcholine in the central nervous system

scientific article published on 20 March 2015

Prostacyclin promotes oligodendrocyte precursor recruitment and remyelination after spinal cord demyelination

scientific article published on 12 September 2013

RGMa inhibition promotes axonal growth and recovery after spinal cord injury.

scientific article

RGMa modulates T cell responses and is involved in autoimmune encephalomyelitis

article

RGMs: Structural Insights, Molecular Regulation, and Downstream Signaling

scientific article published on 19 December 2016

Rap1 is involved in the signal transduction of myelin-associated glycoprotein

scientific article published on 30 November 2007

Regulation of Na+/myo-inositol cotransporter gene expression in hyperglycemic rat hippocampus.

scientific article published in June 1998

Regulation of axonal elongation and pathfinding from the entorhinal cortex to the dentate gyrus in the hippocampus by the chemokine stromal cell-derived factor 1 alpha

scientific journal article

Reorganization of corticospinal tract fibers after spinal cord injury in adult macaques.

scientific article published on July 2015

Repulsive Guidance Molecule A Regulates Adult Neurogenesis Via the Neogenin Receptor

scientific article published on 05 August 2020

Repulsive guidance molecule A suppresses angiogenesis

scientific article published on 22 December 2015

Repulsive guidance molecule a regulates hippocampal mossy fiber branching in vitro

scientific journal article

Repulsive guidance molecule-a is involved in Th17-cell-induced neurodegeneration in autoimmune encephalomyelitis.

scientific article published on 13 November 2014

Rho kinase inhibitor improves motor dysfunction and hypoalgesia in a rat model of lumbar spinal canal stenosis

scientific article published on 01 September 2007

Rho-ROCK inhibitors as emerging strategies to promote nerve regeneration.

scientific article published on January 2007

Rho-ROCK inhibitors for the treatment of CNS injury.

scientific article

Rho-kinase inhibition enhances axonal regeneration after peripheral nerve injury

RhoA activation and effect of Rho-kinase inhibitor in the development of retinal neovascularization in a mouse model of oxygen-induced retinopathy

scientific article published on 01 November 2011

Role of Clast1 in development of cerebellar granule cells.

scientific article published on 30 June 2006

Role of DAPK in neuronal cell death

scientific article published on February 2014

Role of RhoA in activity-dependent cortical axon branching.

scientific article

Sigma-1 receptor enhances neurite elongation of cerebellar granule neurons via TrkB signaling

scientific article

Signaling mechanisms of axon growth inhibition.

scientific article published on November 2006

Soluble β-amyloid Precursor Protein Alpha binds to p75 neurotrophin receptor to promote neurite outgrowth

scientific article

Spatial organization of genome architecture in neuronal development and disease.

scientific article

Suppression of the p75 receptor signal attenuates the effect of ephrin-B3 and promotes axonal regeneration of the injured optic nerve.

scientific article published on 21 March 2013

TACE cleaves neogenin to desensitize cortical neurons to the repulsive guidance molecule.

scientific article published on 27 May 2011

TNF-alpha contributes to axonal sprouting and functional recovery following traumatic brain injury.

scientific article published on 16 July 2009

Temperature dependence of the flexural rigidity of single microtubules

scientific article published on 07 December 2007

Th1 cells promote neurite outgrowth from cortical neurons via a mechanism dependent on semaphorins

scientific article published on 12 October 2010

The First Nationwide Survey and Genetic Analyses of Bardet-Biedl Syndrome in Japan

scientific article published on September 2015

The P2X4 receptor is required for neuroprotection via ischemic preconditioning

scientific article published on 13 May 2016

The RNA-binding protein MARF1 promotes cortical neurogenesis through its RNase activity domain

scientific article

The newly identified migration inhibitory protein regulates the radial migration in the developing neocortex

scientific journal article

The p75 receptor is associated with inflammatory thermal hypersensitivity

scientific article published on 01 December 2008

The role of repulsive guidance molecules in the embryonic and adult vertebrate central nervous system.

scientific article

The soluble form of LOTUS inhibits Nogo receptor-mediated signaling by interfering with the interaction between Nogo receptor type 1 and p75 neurotrophin receptor.

scientific article published on 9 February 2018

Thromboxane A2 stimulates neurite outgrowth in cerebral cortical neurons via mitogen activated protein kinase signaling

scientific article published on 7 August 2014

Transfection of rat cells with proopiomeranocortin gene, precursor of endogenous endorphin, using radial shock waves suppresses inflammatory pain

scientific article published in October 2009

Unconventional role of voltage-gated proton channels (VSOP/Hv1) in regulation of microglial ROS production.

scientific article published on 19 June 2017

Vascular endothelial cells promote cortical neurite outgrowth via an integrin β3-dependent mechanism

scientific article published on 10 June 2014

Wallerian degeneration involves Rho/Rho-kinase signaling

scientific article published on 29 March 2005

Weakened rate-dependent depression of Hoffmann's reflex and increased motoneuron hyperactivity after motor cortical infarction in mice

scientific article

Zyxin is a novel interacting partner for SIRT1

scientific article

c-Jun N-terminal kinase activation in dorsal root ganglion contributes to pain hypersensitivity.

scientific article published in September 2005

c-Jun N-terminal kinase induces axonal degeneration and limits motor recovery after spinal cord injury in mice

scientific article published on 28 July 2011

ifn-γ-dependent secretion of IL-10 from Th1 cells and microglia/macrophages contributes to functional recovery after spinal cord injury

scientific article published on 04 July 2013

p75 neurotrophin receptor signaling in the nervous system.

scientific article published in January 2004

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