List of works - Nathaniel J. Szewczyk

A novel D2O tracer method to quantify RNA turnover as a biomarker of de novo ribosomal biogenesis, in vitro, in animal models, and in human skeletal muscle

scientific article published on 15 August 2017

A validation of the application of D(2)O stable isotope tracer techniques for monitoring day-to-day changes in muscle protein subfraction synthesis in humans

scientific article published on 31 December 2013

Activated EGL-15 FGF receptor promotes protein degradation in muscles of Caenorhabditis elegans

scientific article

Activation of Ras and the mitogen-activated protein kinase pathway promotes protein degradation in muscle cells of Caenorhabditis elegans

scientific article

An overview of technical considerations for Western blotting applications to physiological research.

scientific article

Biochemical and Molecular Biological Analyses of space-flown nematodes in Japan, the First International Caenorhabditis elegans Experiment (ICE-First).

scientific article published on September 2007

C. elegans RNAi space experiment (CERISE) in Japanese Experiment Module KIBO.

scientific article

Caenorhabditis elegans survives atmospheric breakup of STS-107, space shuttle Columbia

scientific article

Calpains mediate integrin attachment complex maintenance of adult muscle in Caenorhabditis elegans

scientific article (publication date: 2012)

Chemically defined medium and Caenorhabditis elegans

scientific article

Commentaries on Viewpoint: A call for research to assess and promote functional resilience in astronaut crews.

scientific article published on February 2016

Comparative analysis of Drosophila melanogaster and Caenorhabditis elegans gene expression experiments in the European Soyuz flights to the International Space Station.

scientific article

Decreased expression of myogenic transcription factors and myosin heavy chains in Caenorhabditis elegans muscles developed during spaceflight

scientific article published on August 2006

Degenerin channel activation causes caspase-mediated protein degradation and mitochondrial dysfunction in adult C. elegans muscle

scientific article

Delayed development and lifespan extension as features of metabolic lifestyle alteration in C. elegans under dietary restriction.

scientific article published in October 2006

Don't 'agonise' over the mechanisms underlying beta-agonist-induced muscle hypertrophy!

scientific article published on 01 January 2011

Effects of leucine and its metabolite β-hydroxy-β-methylbutyrate on human skeletal muscle protein metabolism

scientific article

Evaluation of the Fluids Mixing Enclosure System for Life Science Experiments During a Commercial Caenorhabditis elegans Spaceflight Experiment.

scientific article published on June 2013

Fluid dynamics alter Caenorhabditis elegans body length via TGF-β/DBL-1 neuromuscular signaling

scientific article published on 7 April 2016

Functional phosphatome requirement for protein homeostasis, networked mitochondria, and sarcomere structure in C. elegans muscle

scientific article published on 15 May 2017

Genes down-regulated in spaceflight are involved in the control of longevity in Caenorhabditis elegans

scientific article

Genetic defects in acetylcholine signalling promote protein degradation in muscle cells of Caenorhabditis elegans

scientific article published on 01 June 2000

Genomic response of the nematode Caenorhabditis elegans to spaceflight

scientific article published on January 2008

Glutathione reductase gsr-1 is an essential gene required for Caenorhabditis elegans early embryonic development.

scientific article

Greater loss of mitochondrial function with ageing is associated with earlier onset of sarcopenia in

scientific article published on 01 November 2018

Identification and functional clustering of genes regulating muscle protein degradation from amongst the known C. elegans muscle mutants

scientific article

Impact of the calcium form of β-hydroxy-β-methylbutyrate upon human skeletal muscle protein metabolism.

scientific article published on 6 October 2017

Knockdown of the C. elegans kinome identifies kinases required for normal protein homeostasis, mitochondrial network structure, and sarcomere structure in muscle

scientific article published on 23 September 2013

Methods to assess subcellular compartments of muscle in C. elegans

scientific article

Mice Exposed to Combined Chronic Low-Dose Irradiation and Modeled Microgravity Develop Long-Term Neurological Sequelae ⬇️

scientific article published on 22 August 2019

Microgravity elicits reproducible alterations in cytoskeletal and metabolic gene and protein expression in space-flown Caenorhabditis elegans

scientific article published on 21 January 2016

Mitochondrial dysfunction causes Ca2+ overload and ECM degradation-mediated muscle damage in C. elegans

scientific article published on 04 June 2019

Mitochondrial hydrogen sulfide supplementation improves health in the <i>C. elegans</i> Duchenne muscular dystrophy model

scientific article published on 01 March 2021

Muscle and Tendon Contributions to Reduced Rate of Torque Development in Healthy Older Males

scientific article published on 2 August 2017

Muscle strength deficiency and mitochondrial dysfunction in a muscular dystrophy model of and its functional response to drugs

article

NemaFlex: a microfluidics-based technology for standardized measurement of muscular strength of C. elegans

scientific article published on 01 July 2018

Opposed growth factor signals control protein degradation in muscles of Caenorhabditis elegans

scientific article published on 8 February 2007

Pluronic gel-based burrowing assay for rapid assessment of neuromuscular health in C. elegans

scientific article published on 23 October 2019

Protective role of DNJ-27/ERdj5 in Caenorhabditis elegans models of human neurodegenerative diseases

scientific article published on 3 July 2013

Selenium induces cholinergic motor neuron degeneration in Caenorhabditis elegans

scientific article

Signal-transduction networks and the regulation of muscle protein degradation.

scientific article

Skeletal muscle hypertrophy adaptations predominate in the early stages of resistance exercise training, matching deuterium oxide-derived measures of muscle protein synthesis and mechanistic target of rapamycin complex 1 signaling.

scientific article published on 13 July 2015

Spaceflight affects neuronal morphology and alters transcellular degradation of neuronal debris in adult Caenorhabditis elegans

scientific article published in 2021

Spaceflight and ageing: reflecting on Caenorhabditis elegans in space

scientific article published on 5 November 2013

Surviving atmospheric spacecraft breakup.

scientific article published on January 2005

Synchronous deficits in cumulative muscle protein synthesis and ribosomal biogenesis underlie age-related anabolic resistance to exercise in humans

scientific article published on 22 September 2016

The acute transcriptional response to resistance exercise: impact of age and contraction mode

The effectiveness of RNAi in Caenorhabditis elegans is maintained during spaceflight

scientific article (publication date: 2011)

The glutaredoxin GLRX-21 functions to prevent selenium-induced oxidative stress in Caenorhabditis elegans

scientific article (publication date: December 2010)

The integrin-adhesome is required to maintain muscle structure, mitochondrial ATP production, and movement forces in Caenorhabditis elegans

scientific article

The mechanisms of skeletal muscle atrophy in response to transient knockdown of the vitamin D receptor (VDR) in vivo

scientific article published on 01 December 2020

The neurodegenerative effects of selenium are inhibited by FOXO and PINK1/PTEN regulation of insulin/insulin-like growth factor signaling in Caenorhabditis elegans

scientific article published on 06 January 2014

The next phase of life-sciences spaceflight research: Harnessing the power of functional genomics.

scientific article published on November 2011

Using Multiple Phenotype Assays and Epistasis Testing to Enhance the Reliability of RNAi Screening and Identify Regulators of Muscle Protein Degradation.

scientific article published on 2 November 2012

unc-94 encodes a tropomodulin in Caenorhabditis elegans ⬇️

scientific article

List of works by Nathaniel J. Szewczyk

A novel D2O tracer method to quantify RNA turnover as a biomarker of de novo ribosomal biogenesis, in vitro, in animal models, and in human skeletal muscle

A validation of the application of D(2)O stable isotope tracer techniques for monitoring day-to-day changes in muscle protein subfraction synthesis in humans

Activated EGL-15 FGF receptor promotes protein degradation in muscles of Caenorhabditis elegans

Activation of Ras and the mitogen-activated protein kinase pathway promotes protein degradation in muscle cells of Caenorhabditis elegans

An overview of technical considerations for Western blotting applications to physiological research.

Biochemical and Molecular Biological Analyses of space-flown nematodes in Japan, the First International Caenorhabditis elegans Experiment (ICE-First).

C. elegans RNAi space experiment (CERISE) in Japanese Experiment Module KIBO.

Caenorhabditis elegans survives atmospheric breakup of STS-107, space shuttle Columbia

Calpains mediate integrin attachment complex maintenance of adult muscle in Caenorhabditis elegans

Chemically defined medium and Caenorhabditis elegans

Commentaries on Viewpoint: A call for research to assess and promote functional resilience in astronaut crews.

Comparative analysis of Drosophila melanogaster and Caenorhabditis elegans gene expression experiments in the European Soyuz flights to the International Space Station.

Decreased expression of myogenic transcription factors and myosin heavy chains in Caenorhabditis elegans muscles developed during spaceflight

Degenerin channel activation causes caspase-mediated protein degradation and mitochondrial dysfunction in adult C. elegans muscle

Delayed development and lifespan extension as features of metabolic lifestyle alteration in C. elegans under dietary restriction.

Don't 'agonise' over the mechanisms underlying beta-agonist-induced muscle hypertrophy!

Effects of leucine and its metabolite β-hydroxy-β-methylbutyrate on human skeletal muscle protein metabolism

Evaluation of the Fluids Mixing Enclosure System for Life Science Experiments During a Commercial Caenorhabditis elegans Spaceflight Experiment.

Fluid dynamics alter Caenorhabditis elegans body length via TGF-β/DBL-1 neuromuscular signaling

Functional phosphatome requirement for protein homeostasis, networked mitochondria, and sarcomere structure in C. elegans muscle

Genes down-regulated in spaceflight are involved in the control of longevity in Caenorhabditis elegans

Genetic defects in acetylcholine signalling promote protein degradation in muscle cells of Caenorhabditis elegans

Genomic response of the nematode Caenorhabditis elegans to spaceflight

Glutathione reductase gsr-1 is an essential gene required for Caenorhabditis elegans early embryonic development.

Greater loss of mitochondrial function with ageing is associated with earlier onset of sarcopenia in

Identification and functional clustering of genes regulating muscle protein degradation from amongst the known C. elegans muscle mutants

Impact of the calcium form of β-hydroxy-β-methylbutyrate upon human skeletal muscle protein metabolism.

Knockdown of the C. elegans kinome identifies kinases required for normal protein homeostasis, mitochondrial network structure, and sarcomere structure in muscle

Methods to assess subcellular compartments of muscle in C. elegans

Mice Exposed to Combined Chronic Low-Dose Irradiation and Modeled Microgravity Develop Long-Term Neurological Sequelae ⬇️

Microgravity elicits reproducible alterations in cytoskeletal and metabolic gene and protein expression in space-flown Caenorhabditis elegans

Mitochondrial dysfunction causes Ca2+ overload and ECM degradation-mediated muscle damage in C. elegans

Mitochondrial hydrogen sulfide supplementation improves health in the <i>C. elegans</i> Duchenne muscular dystrophy model

Muscle and Tendon Contributions to Reduced Rate of Torque Development in Healthy Older Males

Muscle strength deficiency and mitochondrial dysfunction in a muscular dystrophy model of and its functional response to drugs

NemaFlex: a microfluidics-based technology for standardized measurement of muscular strength of C. elegans

Opposed growth factor signals control protein degradation in muscles of Caenorhabditis elegans

Pluronic gel-based burrowing assay for rapid assessment of neuromuscular health in C. elegans

Protective role of DNJ-27/ERdj5 in Caenorhabditis elegans models of human neurodegenerative diseases

Selenium induces cholinergic motor neuron degeneration in Caenorhabditis elegans

Signal-transduction networks and the regulation of muscle protein degradation.

Skeletal muscle hypertrophy adaptations predominate in the early stages of resistance exercise training, matching deuterium oxide-derived measures of muscle protein synthesis and mechanistic target of rapamycin complex 1 signaling.

Spaceflight affects neuronal morphology and alters transcellular degradation of neuronal debris in adult Caenorhabditis elegans

Spaceflight and ageing: reflecting on Caenorhabditis elegans in space

Surviving atmospheric spacecraft breakup.

Synchronous deficits in cumulative muscle protein synthesis and ribosomal biogenesis underlie age-related anabolic resistance to exercise in humans

The acute transcriptional response to resistance exercise: impact of age and contraction mode

The effectiveness of RNAi in Caenorhabditis elegans is maintained during spaceflight

The glutaredoxin GLRX-21 functions to prevent selenium-induced oxidative stress in Caenorhabditis elegans

The integrin-adhesome is required to maintain muscle structure, mitochondrial ATP production, and movement forces in Caenorhabditis elegans

The mechanisms of skeletal muscle atrophy in response to transient knockdown of the vitamin D receptor (VDR) in vivo

The neurodegenerative effects of selenium are inhibited by FOXO and PINK1/PTEN regulation of insulin/insulin-like growth factor signaling in Caenorhabditis elegans

The next phase of life-sciences spaceflight research: Harnessing the power of functional genomics.

Using Multiple Phenotype Assays and Epistasis Testing to Enhance the Reliability of RNAi Screening and Identify Regulators of Muscle Protein Degradation.

unc-94 encodes a tropomodulin in Caenorhabditis elegans ⬇️