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List of works by Sara Lonardi

5-Fluorouracil and Weekly Oxaliplatin Combined with Radiotherapy for Locally Advanced Rectal Cancer: Surgical Complications and Long-term Results

scientific article published on 01 October 2006

A new nomogram for estimating survival in patients with brain metastases secondary to colorectal cancer

scientific article published on 4 September 2015

A phase I-II study of weekly oxaliplatin, 5-fluorouracil continuous infusion and preoperative radiotherapy in locally advanced rectal cancer.

scientific article published on 13 May 2005

Addition of weekly oxaliplatin to standard preoperative chemoradiation for locally advanced rectal cancer

scientific article published on 01 February 2007

Adjuvant chemotherapy in the treatment of high grade gliomas.

scientific article

Adjuvant systemic chemotherapy with 5-fluorouracil and leucovorin in colon cancer: a monoinstitutional institutional experience

scientific article published on 01 January 2008

Advanced age and liability to oxaliplatin-induced peripheral neuropathy: post hoc analysis of a prospective study

scientific article published on 17 December 2012

Advanced gastric cancer (GC) and cancer of the gastro-oesophageal junction (GEJ): focus on targeted therapies.

scientific article published on 20 January 2011

An untreatable dyspnoea: more defendants under investigation

scientific article published on 14 February 2017

Angiogenesis inhibitors and symptomatic anal ulcers in metastatic colorectal cancer patients *.

scientific article published on 15 July 2017

Anti-EGFR monoclonal antibody panitumumab for the treatment of patients with metastatic colorectal cancer: an overview of current practice and future perspectives.

scientific article

Are Dose-Finding Studies Still Necessary When Targeted Therapy Is Associated With Chemotherapy?

scientific article published on 01 October 2006

Assessment of a HER2 scoring system for colorectal cancer: results from a validation study

scientific article published on 09 October 2015

Assessment of intratumor immune-microenvironment in colorectal cancers with extranodal extension of nodal metastases

scientific article published on 06 September 2018

Association of STAT-3 rs1053004 and VDR rs11574077 With FOLFIRI-Related Gastrointestinal Toxicity in Metastatic Colorectal Cancer Patients.

scientific article published on 13 April 2018

Association of theHLA-G3′UTR polymorphisms with colorectal cancer in Italy: a first insight

scientific article (publication date: 21 December 2015)

Autophagy-related polymorphisms predict hypertension in patients with metastatic colorectal cancer treated with FOLFIRI and bevacizumab: Results from TRIBE and FIRE-3 trials.

scientific article published on 24 March 2017

BRAF and RAS mutations as prognostic factors in metastatic colorectal cancer patients undergoing liver resection.

scientific article

BRAF codons 594 and 596 mutations identify a new molecular subtype of metastatic colorectal cancer at favorable prognosis

scientific article published on 7 July 2015

BRAF p.V600E-specific immunohistochemical assessment in colorectal cancer endoscopy biopsies is consistent with the mutational profiling

scientific article

Bone metastases in biliary cancers: A multicenter retrospective survey

scientific article published on 07 April 2018

Cancer in the elderly

Carboplatin and teniposide as third-line chemotherapy in patients with recurrent oligodendroglioma or oligoastrocytoma: a phase II study.

scientific article

Chemotherapy for operable and advanced colorectal cancer.

scientific article published on 29 May 2009

Circulating cell-free DNA: a promising marker of pathologic tumor response in rectal cancer patients receiving preoperative chemoradiotherapy

scientific article published on 17 March 2011

Clinical impact of anti-epidermal growth factor receptor monoclonal antibodies in first-line treatment of metastatic colorectal cancer

scientific article published on 25 August 2011

Clinical validity of a DPYD-based pharmacogenetic test to predict severe toxicity to fluoropyrimidines

scientific article published on 23 June 2015

Colon cancer in elderly patients: what is the best treatment?

Complications, functional outcome and quality of life after intensive preoperative chemoradiotherapy for rectal cancer.

scientific article published on 26 July 2006

Comprehensive Genomic Profiling (CGP)-Informed Personalized Molecular Residual Disease (MRD) Detection: An Exploratory Analysis from the PREDATOR Study of Metastatic Colorectal Cancer (mCRC) Patients Undergoing Surgical Resection

scientific article published in 2022

Correction to: Assessment of intratumor immune-microenvironment in colorectal cancers with extranodal extension of nodal metastases

scientific article published on 24 September 2019

DPYD and UGT1A1 genotyping to predict adverse events during first-line FOLFIRI or FOLFOXIRI plus bevacizumab in metastatic colorectal cancer.

scientific article published on 21 December 2017

Deleted in colon cancer protein expression in colorectal cancer metastases: a major predictor of survival in patients with unresectable metastatic disease receiving palliative fluorouracil-based chemotherapy

scientific article published on September 2004

Development of an oncological-multidimensional prognostic index (Onco-MPI) for mortality prediction in older cancer patients

scientific article published on 12 January 2016

Differential histopathologic parameters in colorectal cancer liver metastases resected after triplets plus bevacizumab or cetuximab: a pooled analysis of five prospective trials.

scientific article published on 13 March 2018

Dihydropyrimidine dehydrogenase pharmacogenetics for predicting fluoropyrimidine-related toxicity in the randomised, phase III adjuvant TOSCA trial in high-risk colon cancer patients.

scientific article published on 24 August 2017

Dual-targeted therapy with trastuzumab and lapatinib in treatment-refractory, KRAS codon 12/13 wild-type, HER2-positive metastatic colorectal cancer (HERACLES): a proof-of-concept, multicentre, open-label, phase 2 trial

scientific article

Durable Clinical Benefit With Nivolumab Plus Ipilimumab in DNA Mismatch Repair-Deficient/Microsatellite Instability-High Metastatic Colorectal Cancer

scientific article

Early predictors of oxaliplatin-induced cumulative neuropathy in colorectal cancer patients

scientific article published on 29 June 2013

Early tumor shrinkage and depth of response predict long-term outcome in metastatic colorectal cancer patients treated with first-line chemotherapy plus bevacizumab: results from phase III TRIBE trial by the Gruppo Oncologico del Nord Ovest

scientific article published on 23 February 2015

Exposure-response relationship of ramucirumab in patients with advanced second-line colorectal cancer: exploratory analysis of the RAISE trial

scientific article

FOLFOXIRI in combination with panitumumab as first-line treatment in quadruple wild-type (KRAS, NRAS, HRAS, BRAF) metastatic colorectal cancer patients: a phase II trial by the Gruppo Oncologico Nord Ovest (GONO).

scientific article published on 10 May 2013

FOLFOXIRI or FOLFOXIRI plus bevacizumab as first-line treatment of metastatic colorectal cancer: a propensity score-adjusted analysis from two randomized clinical trials.

scientific article published on 9 February 2016

FOLFOXIRI plus bevacizumab as first-line treatment in BRAF mutant metastatic colorectal cancer

scientific article published on 15 October 2013

FOLFOXIRI plus bevacizumab versus FOLFIRI plus bevacizumab as first-line treatment of patients with metastatic colorectal cancer: updated overall survival and molecular subgroup analyses of the open-label, phase 3 TRIBE study.

scientific article

First-line FOLFIRI and bevacizumab in patients with advanced colorectal cancer prospectively stratified according to serum LDH: final results of the GISCAD (Italian Group for the Study of Digestive Tract Cancers) CENTRAL (ColorEctalavastiNTRiAlLdh)

scientific article published on 19 September 2017

From CENTRAL to SENTRAL (SErum aNgiogenesis cenTRAL): Circulating Predictive Biomarkers to Anti-VEGFR Therapy

scientific article published on 22 May 2020

Gefitinib in patients with progressive high-grade gliomas: a multicentre phase II study by Gruppo Italiano Cooperativo di Neuro-Oncologia (GICNO).

scientific article published on 13 March 2007

Gene Polymorphisms in the CCL5/CCR5 Pathway as a Genetic Biomarker for Outcome and Hand-Foot Skin Reaction in Metastatic Colorectal Cancer Patients Treated With Regorafenib.

scientific article published on 27 February 2018

Genetic Variants of the TERT Gene, Telomere Length, and Circulating TERT as Prognostic Markers in Rectal Cancer Patients

scientific article published on 25 October 2020

Genetic determinants of chronic oxaliplatin-induced peripheral neurotoxicity: a genome-wide study replication and meta-analysis.

scientific article published on March 2015

Genetic markers for toxicity of adjuvant oxaliplatin and fluoropyrimidines in the phase III TOSCA trial in high-risk colon cancer patients

scientific article

HER2–CDH1 Interaction via Wnt/B-Catenin Is Associated with Patients’ Survival in HER2-Positive Metastatic Gastric Adenocarcinoma

scientific article published in 2022

HLA-G 3'UTR Polymorphisms Impact the Prognosis of Stage II-III CRC Patients in Fluoropyrimidine-Based Treatment.

scientific article published on 3 December 2015

Health-related quality of life, faecal continence and bowel function in rectal cancer patients after chemoradiotherapy followed by radical surgery.

scientific article published on 23 July 2009

Hepatoid adenocarcinoma of the colon: what should we target?

scientific article published on 12 June 2011

Heterogeneity of Acquired Resistance to Anti-EGFR Monoclonal Antibodies in Patients with Metastatic Colorectal Cancer.

scientific article published on 25 October 2016

Immune senescence and cancer in elderly patients: results from an exploratory study

scientific article published on 10 October 2013

Immunotherapy in Gastrointestinal Cancers.

scientific article published on 3 July 2017

Incidence of atypical acute nerve hyperexcitability symptoms in oxaliplatin-treated patients with colorectal cancer

scientific article published on 30 October 2012

Initial therapy with FOLFOXIRI and bevacizumab for metastatic colorectal cancer.

scientific article

Is intra-arterial chemotherapy useful in high-grade gliomas?

scientific article

Liver Resection for Advanced Intrahepatic Cholangiocarcinoma: A Cost-Utility Analysis.

scientific article published on 07 July 2015

Location of Primary Tumor and Benefit From Anti-Epidermal Growth Factor Receptor Monoclonal Antibodies in Patients With RAS and BRAF Wild-Type Metastatic Colorectal Cancer.

scientific article published on 5 July 2016

Long-term oncologic results and complications after preoperative chemoradiotherapy for rectal cancer: a single-institution experience after a median follow-up of 95 months.

scientific article

MTHFR-1298 A>C (rs1801131) is a predictor of survival in two cohorts of stage II/III colorectal cancer patients treated with adjuvant fluoropyrimidine chemotherapy with or without oxaliplatin

scientific article published on 21 October 2014

Male breast cancer: clinical features and multimodal treatment in a retrospective survey analysis at Italian centers

scientific article published in September 2013

Multidisciplinary management is strongly suggested in elderly patients with rectal carcinoma

Multidisciplinary treatment of rectal cancer: medical oncology

scientific article published on 01 November 2007

Multidisciplinary treatment of rectal cancer: medical oncology.

scientific article published on July 2007

Multivariate prognostic factors analysis for second-line chemotherapy in advanced biliary tract cancer.

scientific article

NOS2 polymorphisms in prediction of benefit from first-line chemotherapy in metastatic colorectal cancer patients

scientific article published on 9 March 2018

New perspectives for TAS-102: TASK successful?

scientific article published on 28 July 2017

Nivolumab in patients with metastatic DNA mismatch repair-deficient or microsatellite instability-high colorectal cancer (CheckMate 142): an open-label, multicentre, phase 2 study.

scientific article published on 19 July 2017

Oral anticancer drugs in the elderly: an overview

scientific article published on January 2007

Peripheral neurotoxicity of oxaliplatin in combination with 5-fluorouracil (FOLFOX) or capecitabine (XELOX): a prospective evaluation of 150 colorectal cancer patients

scientific article published on 2 August 2012

Pharmacogenetics Biomarkers and Their Specific Role in Neoadjuvant Chemoradiotherapy Treatments: An Exploratory Study on Rectal Cancer Patients.

scientific article published on 05 September 2016

Pharmacokinetic analysis of metronomic capecitabine in refractory metastatic colorectal cancer patients

scientific article published on 27 February 2018

Phase II Study of Tivantinib and Cetuximab in Patients With KRAS Wild-type Metastatic Colorectal Cancer With Acquired Resistance to EGFR Inhibitors and Emergence of MET Overexpression: Lesson Learned for Future Trials With EGFR/MET Dual Inhibition

scientific article published on 14 February 2019

Phase II study of single-agent cetuximab in KRAS G13D mutant metastatic colorectal cancer.

scientific article

Phase III Trial of Avelumab Maintenance After First-Line Induction Chemotherapy Versus Continuation of Chemotherapy in Patients With Gastric Cancers: Results From JAVELIN Gastric 100

scientific article published on 16 November 2020

Phase III trial comparing 3-6 months of adjuvant FOLFOX4/XELOX in stage II-III colon cancer: safety and compliance in the TOSCA trial

scientific article

Predictive role of microRNA-related genetic polymorphisms in the pathological complete response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer patients

scientific article published on 26 February 2016

Prevalence of pain in patients with cancer aged 70 years or older: A prospective observational study

scientific article published on 25 January 2019

Primary Tumor Response to Preoperative Chemoradiation With or Without Oxaliplatin in Locally Advanced Rectal Cancer: Pathologic Results of the STAR-01 Randomized Phase III Trial ⬇️

scientific article published on May 23, 2011

Prognostic Value of Thyroid Hormone Ratios in Patients With Advanced Metastatic Colorectal Cancer Treated With Regorafenib: The TOREADOR Study

scientific article published on 08 June 2018

Prognostic significance of AMPK activation in advanced stage colorectal cancer treated with chemotherapy plus bevacizumab

scientific article

Prospective validation of candidate SNPs of VEGF/VEGFR pathway in metastatic colorectal cancer patients treated with first-line FOLFIRI plus bevacizumab

scientific article

QoL is a cool tool.

scientific article published on 18 April 2017

RNF43 mutations predict response to anti-BRAF/EGFR combinatory therapies in BRAFV600E metastatic colorectal cancer

scientific article published in 2022

Ramucirumab as Second-Line Therapy in Metastatic Gastric Cancer: Real-World Data from the RAMoss Study

scientific article published on 27 March 2018

Ramucirumab for the treatment of gastric cancers, colorectal adenocarcinomas, and other gastrointestinal malignancies.

scientific article published on 5 May 2016

Rectal sparing approach after preoperative radio- and/or chemotherapy (RESARCH) in patients with rectal cancer: a multicentre observational study

scientific article published on 28 July 2017

Second-line chemotherapy in advanced biliary cancer progressed to first-line platinum-gemcitabine combination: a multicenter survey and pooled analysis with published data

scientific article

Second-line chemotherapy in advanced biliary cancer: the present now will later be past

scientific article published on 13 August 2014

Significance of pulmonary nodules in patients with colorectal cancer ⬇️

scientific article published on April 1, 2012

Single Nucleotide Polymorphisms in MiRNA Binding Sites of Nucleotide Excision Repair-Related Genes Predict Clinical Benefit of Oxaliplatin in FOLFOXIRI Plus Bevacizumab: Analysis of the TRIBE Trial

scientific article published on 30 June 2020

Single-Agent Panitumumab in Frail Elderly Patients With Advanced RAS and BRAF Wild-Type Colorectal Cancer: Challenging Drug Label to Light Up New Hope

scientific article

Subgroup analysis in RAISE: a randomized, double-blind phase III study of irinotecan, folinic acid, and 5-fluorouracil (FOLFIRI) plus ramucirumab or placebo in patients with metastatic colorectal carcinoma progression

scientific article published on 29 August 2016

TP53 Mutation Analysis in Gastric Cancer and Clinical Outcomes of Patients with Metastatic Disease Treated with Ramucirumab/Paclitaxel or Standard Chemotherapy

scientific article published on 24 July 2020

TRIBE-2: a phase III, randomized, open-label, strategy trial in unresectable metastatic colorectal cancer patients by the GONO group.

scientific article

Telomerase is an independent prognostic marker of overall survival in patients with colorectal cancer

scientific article published on 15 January 2013

Telomere-Specific Reverse Transcriptase (hTERT) and Cell-free RNA in Plasma as Predictors of Pathologic Tumor Response in Rectal Cancer Patients Receiving Neoadjuvant Chemoradiotherapy

article

The PANDA study: a randomized phase II study of first-line FOLFOX plus panitumumab versus 5FU plus panitumumab in RAS and BRAF wild-type elderly metastatic colorectal cancer patients.

scientific article published on 25 January 2018

The role of pharmacogenetics in the new ESMO colorectal cancer guidelines.

scientific article published on 23 January 2017

The role of tumor angiogenesis as a therapeutic target in colorectal cancer

scientific article published on 17 January 2018

Thymidylate Synthase expression as a predictor of clinical response to fluoropyrimidine-based chemotherapy in advanced colorectal cancer.

scientific article

Thymidylate synthase protein expression in colorectal cancer metastases predicts for clinical outcome to leucovorin-modulated bolus or infusional 5-fluorouracil but not methotrexate-modulated bolus 5-fluorouracil

scientific article published on December 2002

Transarterial Chemoembolization with Small Drug-Eluting Beads in Patients with Hepatocellular Carcinoma: Experience from a Cohort of 421 Patients at an Italian Center.

scientific article published on 16 September 2017

Treatment of advanced breast cancer in elderly women: medical approach

Treatment sequence with either irinotecan/cetuximab followed by FOLFOX-4 or the reverse strategy in metastatic colorectal cancer patients progressing after first-line FOLFIRI/bevacizumab: An Italian Group for the Study of Gastrointestinal Cancer pha

scientific article published on 20 July 2017

Ultrasound assessment of oxaliplatin-induced neuropathy and correlations with neurophysiologic findings

scientific article published on 04 September 2012

Use of sorafenib in patients with hepatocellular carcinoma before liver transplantation: a cost-benefit analysis while awaiting data on sorafenib safety

scientific article

Vinorelbine in BRAF V600E mutated metastatic colorectal cancer: a prospective multicentre phase II clinical study.

scientific article published on 10 August 2017

Voltage-gated sodium channel polymorphisms play a pivotal role in the development of oxaliplatin-induced peripheral neurotoxicity: results from a prospective multicenter study

scientific article

Which benefit from adding gemcitabine to vinorelbine in elderly (>or=70 years) women with metastatic breast cancer? Early interruption of a phase II study

scientific article published on 6 October 2006

miR-224 Is Significantly Upregulated and Targets Caspase-3 and Caspase-7 During Colorectal Carcinogenesis

scientific article published on 16 November 2018

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