List of works - Andriy Khobta

8-Oxo-7,8-dihydroguanine in DNA does not constitute a barrier to transcription, but is converted into transcription-blocking damage by OGG1.

scientific article published on 25 March 2011

8-Oxoguanine DNA glycosylase (Ogg1) causes a transcriptional inactivation of damaged DNA in the absence of functional Cockayne syndrome B (Csb) protein.

scientific article

Cockayne syndrome: varied requirement of transcription-coupled nucleotide excision repair for the removal of three structurally different adducts from transcribed DNA

scientific article (publication date: 2014)

EGFP Reporters for Direct and Sensitive Detection of Mutagenic Bypass of DNA Lesions

scientific article published on 13 June 2020

Early effects of topoisomerase I inhibition on RNA polymerase II along transcribed genes in human cells

scientific article published on 6 January 2006

Enhanced CPT sensitivity of yeast cells and selective relaxation of Ga14 motif-containing DNA by novel Gal4-topoisomerase I fusion proteins

scientific article published in March 2004

Functional impacts of 5-hydroxymethylcytosine, 5-formylcytosine, and 5-carboxycytosine at a single hemi-modified CpG dinucleotide in a gene promoter.

scientific article published on 17 August 2017

G1 cell-cycle arrest and apoptosis by histone deacetylase inhibition in MLL-AF9 acute myeloid leukemia cells is p21 dependent and MLL-AF9 independent

scientific article published on 13 April 2006

Generation of reporter plasmids containing defined base modifications in the DNA strand of choice ⬇️

scientific article published on March 8, 2012

Influences of histone deacetylase inhibitors and resveratrol on DNA repair and chromatin compaction

scientific article published on 29 June 2013

Interactions between DNA damage, repair, and transcription.

scientific article published on 12 August 2011

Modulation of base excision repair of 8-oxoguanine by the nucleotide sequence

scientific article published on 17 July 2013

Mouse CSB protein is important for gene expression in the presence of a single-strand break in the non-transcribed DNA strand

scientific article published on 31 July 2010

Nucleotide excision repair of abasic DNA lesions

scientific article published on 01 September 2019

Repair of oxidatively generated DNA damage in Cockayne syndrome.

scientific article published on 18 March 2013

Specific histone patterns and acetylase/deacetylase activity at the breakpoint-cluster region of the human MLL gene