List of works - Dorothy M Supp

Abnormal expression of the vitamin D receptor in keloid scars.

scientific article published in August 2017

Analysis of chromatin accessibility in human epidermis identifies putative barrier dysfunction-sensing enhancers.

scientific article published on 27 September 2017

Burn Scar Biomechanics after Pressure Garment Therapy.

scientific article published on 8 May 2015

Collagen VII Expression Is Required in Both Keratinocytes and Fibroblasts for Anchoring Fibril Formation in Bilayer Engineered Skin Substitutes

scientific article published on 04 July 2019

Conserved left-right asymmetry of nodal expression and alterations in murine situs inversus.

scientific article

Correlation of forelimb malformation asymmetries with visceral organ situs in the transgenic mouse insertional mutation, legless

scientific article published on 01 August 1993

Culture medium and cell density impact gene expression in normal skin and abnormal scar-derived fibroblasts.

scientific article published in July 2011

Deep and superficial keloid fibroblasts contribute differentially to tissue phenotype in a novel in vivo model of keloid scar

scientific article published on 01 June 2012

Defining MC1R regulation in human melanocytes by its agonist α-melanocortin and antagonists agouti signaling protein and β-defensin 3.

scientific article published on 10 May 2012

Disease-associated KIF3A variants alter gene methylation and expression impacting skin barrier and atopic dermatitis risk

scientific article published on 14 August 2020

Early cessation of pressure garment therapy results in scar contraction and thickening.

scientific article published on 13 June 2018

Effect of skin graft thickness on scar development in a porcine burn model.

scientific article published on 13 April 2018

Effects of early combinatorial treatment of autologous split-thickness skin grafts in red duroc pig model using pulsed dye laser and fractional CO2 laser.

scientific article

Engineered human skin substitutes undergo large-scale genomic reprogramming and normal skin-like maturation after transplantation to athymic mice

scientific article published on 01 October 2009

Engineered skin substitutes: practices and potentials

scientific article

Enhanced expression of limb malformations and axial skeleton alterations in legless mutants by transplacental exposure to retinoic acid

scientific article published on 01 July 1994

Expression of genes encoding antimicrobial proteins and members of the toll-like receptor/nuclear factor-kappaB pathways in engineered human skin.

scientific article published in July 2008

Expression of human beta defensin 4 in genetically modified keratinocytes enhances antimicrobial activity.

scientific article published in January 2007

Expression of human beta-defensins HBD-1, HBD-2, and HBD-3 in cultured keratinocytes and skin substitutes

scientific article published in November 2004

Gene therapy to fight infection in skin transplants.

scientific article published in May 2007

Genomic Reprogramming and Skin-Like Maturation of Engineered Human Skin Substitutes.

scientific article published on April 2012

Handed asymmetry in the mouse: understanding how things go right (or left) by studying how they go wrong.

scientific article published on February 1998

Human dermal microvascular endothelial cells form vascular analogs in cultured skin substitutes after grafting to athymic mice.

scientific article published on June 2002

Identification of Merkel cells associated with neurons in engineered skin substitutes after grafting to full thickness wounds

scientific article published on 05 March 2019

Inflammatory response and biomechanical properties of coaxial scaffolds for engineered skin in vitro and post-grafting

scientific article published on 12 September 2018

Inflammatory responses, matrix remodeling, and re-epithelialization after fractional CO2 laser treatment of scars.

scientific article

Influence of electrospun collagen on wound contraction of engineered skin substitutes.

scientific article

Inhibition of hyaluronan synthase 2 reduces the abnormal migration rate of keloid keratinocytes.

scientific article published in January 2014

Keloid-derived keratinocytes exhibit an abnormal gene expression profile consistent with a distinct causal role in keloid pathology.

scientific article published in July 2013

Keratin expression in cultured skin substitutes suggests that the hyperproliferative phenotype observed in vitro is normalized after grafting

scientific article published in March 2006

LETTER TO THE EDITOR Abnormal Responses of Keloid Tissue to Wounding Identified Using In Vitro Model System ⬇️

scientific article published on April 12, 2012

Local expression of indoleamine 2,3-dioxygenase suppresses T-cell-mediated rejection of an engineered bilayer skin substitute.

scientific article published on 18 October 2010

Melanocortin 1 receptor genotype: an important determinant of the damage response of melanocytes to ultraviolet radiation.

scientific article published on 2 June 2010

Microarray analysis of gene expression in cultured skin substitutes compared with native human skin

scientific article published in December 2005

Molecular motors: the driving force behind mammalian left-right development.

scientific article

Morphogenesis of chimeric hair follicles in engineered skin substitutes with human keratinocytes and murine dermal papilla cells.

scientific article published in October 2012

Mutation of an axonemal dynein affects left–right asymmetry in inversus viscerum mice ⬇️

scientific article published on October 30, 1997

Novel burn device for rapid, reproducible burn wound generation

scientific article published on 20 January 2016

Overexpression of vascular endothelial growth factor accelerates early vascularization and improves healing of genetically modified cultured skin substitutes

scientific article published on 01 January 2002

Partial epithelial-mesenchymal transition in keloid scars: regulation of keloid keratinocyte gene expression by transforming growth factor-β1

scientific article published on 23 August 2016

Restoration of cutaneous pigmentation by transplantation to mice of isogeneic human melanocytes in dermal-epidermal engineered skin substitutes.

scientific article published on 22 June 2017

Role of Arginine and Omega-3 Fatty Acids in Wound Healing and Infection

scientific article published on November 2014

Role of Early Application of Pressure Garments following Burn Injury and Autografting

scientific article published on 01 February 2019

Scar formation following excisional and burn injuries in a red Duroc pig model

scientific article published on 20 July 2017

Soluble Epoxide Hydrolase Inhibition and Epoxyeicosatrienoic Acid Treatment Improve Vascularization of Engineered Skin Substitutes

scientific article published on 20 December 2016

Sp4, a member of the Sp1-family of zinc finger transcription factors, is required for normal murine growth, viability, and male fertility

scientific article published in June 1996

Structural, Chemical, and Mechanical Properties of Pressure Garments as a Function of Simulated Use and Repeated Laundering

scientific article published on 01 June 2018

Tumorigenicity Testing in Athymic Mice of Cultured Human Melanocytes for Transplantation in Engineered Skin Substitutes

scientific article published on 23 July 2014

Uniaxial strain regulates morphogenesis, gene expression, and tissue strength in engineered skin

scientific article published on 01 March 2010

Vascular endothelial growth factor overexpression increases vascularization by murine but not human endothelial cells in cultured skin substitutes grafted to athymic mice.

scientific article published on July 2004

beta-Defensin 3: a novel and unexpected key that unlocks the melanocortin 1 receptor.

scientific article published in February 2008

List of works by Dorothy M Supp

Abnormal expression of the vitamin D receptor in keloid scars.

Analysis of chromatin accessibility in human epidermis identifies putative barrier dysfunction-sensing enhancers.

Burn Scar Biomechanics after Pressure Garment Therapy.

Collagen VII Expression Is Required in Both Keratinocytes and Fibroblasts for Anchoring Fibril Formation in Bilayer Engineered Skin Substitutes

Conserved left-right asymmetry of nodal expression and alterations in murine situs inversus.

Correlation of forelimb malformation asymmetries with visceral organ situs in the transgenic mouse insertional mutation, legless

Culture medium and cell density impact gene expression in normal skin and abnormal scar-derived fibroblasts.

Deep and superficial keloid fibroblasts contribute differentially to tissue phenotype in a novel in vivo model of keloid scar

Defining MC1R regulation in human melanocytes by its agonist α-melanocortin and antagonists agouti signaling protein and β-defensin 3.

Disease-associated KIF3A variants alter gene methylation and expression impacting skin barrier and atopic dermatitis risk

Early cessation of pressure garment therapy results in scar contraction and thickening.

Effect of skin graft thickness on scar development in a porcine burn model.

Effects of early combinatorial treatment of autologous split-thickness skin grafts in red duroc pig model using pulsed dye laser and fractional CO2 laser.

Engineered human skin substitutes undergo large-scale genomic reprogramming and normal skin-like maturation after transplantation to athymic mice

Engineered skin substitutes: practices and potentials

Enhanced expression of limb malformations and axial skeleton alterations in legless mutants by transplacental exposure to retinoic acid

Expression of genes encoding antimicrobial proteins and members of the toll-like receptor/nuclear factor-kappaB pathways in engineered human skin.

Expression of human beta defensin 4 in genetically modified keratinocytes enhances antimicrobial activity.

Expression of human beta-defensins HBD-1, HBD-2, and HBD-3 in cultured keratinocytes and skin substitutes

Gene therapy to fight infection in skin transplants.

Genomic Reprogramming and Skin-Like Maturation of Engineered Human Skin Substitutes.

Handed asymmetry in the mouse: understanding how things go right (or left) by studying how they go wrong.

Human dermal microvascular endothelial cells form vascular analogs in cultured skin substitutes after grafting to athymic mice.

Identification of Merkel cells associated with neurons in engineered skin substitutes after grafting to full thickness wounds

Inflammatory response and biomechanical properties of coaxial scaffolds for engineered skin in vitro and post-grafting

Inflammatory responses, matrix remodeling, and re-epithelialization after fractional CO2 laser treatment of scars.

Influence of electrospun collagen on wound contraction of engineered skin substitutes.

Inhibition of hyaluronan synthase 2 reduces the abnormal migration rate of keloid keratinocytes.

Keloid-derived keratinocytes exhibit an abnormal gene expression profile consistent with a distinct causal role in keloid pathology.

Keratin expression in cultured skin substitutes suggests that the hyperproliferative phenotype observed in vitro is normalized after grafting

LETTER TO THE EDITOR Abnormal Responses of Keloid Tissue to Wounding Identified Using In Vitro Model System ⬇️

Local expression of indoleamine 2,3-dioxygenase suppresses T-cell-mediated rejection of an engineered bilayer skin substitute.

Melanocortin 1 receptor genotype: an important determinant of the damage response of melanocytes to ultraviolet radiation.

Microarray analysis of gene expression in cultured skin substitutes compared with native human skin

Molecular motors: the driving force behind mammalian left-right development.

Morphogenesis of chimeric hair follicles in engineered skin substitutes with human keratinocytes and murine dermal papilla cells.

Mutation of an axonemal dynein affects left–right asymmetry in inversus viscerum mice ⬇️

Novel burn device for rapid, reproducible burn wound generation

Overexpression of vascular endothelial growth factor accelerates early vascularization and improves healing of genetically modified cultured skin substitutes

Partial epithelial-mesenchymal transition in keloid scars: regulation of keloid keratinocyte gene expression by transforming growth factor-β1

Restoration of cutaneous pigmentation by transplantation to mice of isogeneic human melanocytes in dermal-epidermal engineered skin substitutes.

Role of Arginine and Omega-3 Fatty Acids in Wound Healing and Infection

Role of Early Application of Pressure Garments following Burn Injury and Autografting

Scar formation following excisional and burn injuries in a red Duroc pig model

Soluble Epoxide Hydrolase Inhibition and Epoxyeicosatrienoic Acid Treatment Improve Vascularization of Engineered Skin Substitutes

Sp4, a member of the Sp1-family of zinc finger transcription factors, is required for normal murine growth, viability, and male fertility

Structural, Chemical, and Mechanical Properties of Pressure Garments as a Function of Simulated Use and Repeated Laundering

Tumorigenicity Testing in Athymic Mice of Cultured Human Melanocytes for Transplantation in Engineered Skin Substitutes

Uniaxial strain regulates morphogenesis, gene expression, and tissue strength in engineered skin

Vascular endothelial growth factor overexpression increases vascularization by murine but not human endothelial cells in cultured skin substitutes grafted to athymic mice.

beta-Defensin 3: a novel and unexpected key that unlocks the melanocortin 1 receptor.