List of works - Sofia Ramström

A cluster of aspartic residues in the extracellular loop II of PAR 4 is important for thrombin interaction and activation of platelets

scientific article published on 13 April 2017

Adrenaline Improves Platelet Reactivity in Ticagrelor-Treated Healthy Volunteers

scientific article published on 19 February 2019

Adrenaline enhances in vitro platelet activation and aggregation in blood samples from ticagrelor-treated patients

scientific article published on 30 September 2018

Annexin V binding to platelets is agonist, time and temperature dependent.

scientific article published in January 2010

Arachidonic acid causes lysis of blood cells and ADP-dependent platelet activation responses in platelet function tests

scientific article published on 24 December 2018

Assays of different aspects of haemostasis - what do they measure?

scientific article

Better platelet function, less fibrinolysis and less hemolysis in re-transfused residual pump blood with the Ringer's chase technique - a randomized pilot study.

scientific article published in September 2017

Caveats in studies of the physiological role of polyphosphates in coagulation

scientific article published on February 2016

Clotting time analysis of citrated blood samples is strongly affected by the tube used for blood sampling

scientific article published on 01 September 2005

Clotting time by free oscillation rheometry and visual inspection and a viscoelastic description of the clotting phenomenon ⬇️

scientific article published on January 1, 2003

Comparative analysis of obesity-related cardiometabolic and renal biomarkers in human plasma and serum

scientific article published on 28 October 2019

Contact activation: important to consider when measuring the contribution of tissue factor-bearing microparticles to thrombin generation using phospholipid-containing reagents.

scientific article

Detection of Lysosomal Exocytosis in Platelets by Flow Cytometry

scientific article published in January 2017

Effects of inhibition of P2Y(1) and P2Y(12) on whole blood clotting, coagulum elasticity and fibrinolysis resistance studied with free oscillation rheometry.

scientific article

Flow cytometry-based platelet function testing is predictive of symptom burden in a cohort of bleeders.

scientific article published on 12 September 2017

Free oscillation rheometry detects changes in clot properties in pregnancy and thrombocytopenia

scientific article

Gradient-dependent inhibition of stimulatory signaling from platelet G protein-coupled receptors

scientific article published on 10 January 2019

Identification of low-density platelet populations with increased reactivity and elevated alpha-granule content.

scientific article

Increased Thrombopoiesis and Platelet Activation in Hantavirus-Infected Patients

scientific article

Lipoxin A₄ inhibits porphyromonas gingivalis-induced aggregation and reactive oxygen species production by modulating neutrophil-platelet interaction and CD11b expression

scientific article

Methods for evaluation of platelet function

scientific article published on 21 August 2009

PO-55 - Individual variation in hemostatic alterations caused by tyrosine kinase inhibitors - a way to improve personalized cancer therapy?

scientific article

Platelet Function Determined by Flow Cytometry: New Perspectives?

scientific article published on 17 February 2016

Platelet PAR1 receptor density--correlation to platelet activation response and changes in exposure after platelet activation

scientific article published on 01 August 2007

Platelet activation via PAR4 is involved in the initiation of thrombin generation and in clot elasticity development

scientific article published on 01 March 2007

Platelet adhesion changes during storage studied with a novel method using flow cytometry and protein-coated beads.

scientific article

Platelet function testing at low platelet counts: When can you trust your analysis?

scientific article published on 19 March 2019

Platelet phosphatidylserine exposure and procoagulant activity in clotting whole blood--different effects of collagen, TRAP and calcium ionophore A23187.

scientific article published in January 2003

Platelet subpopulations remain despite strong dual agonist stimulation and can be characterised using a novel six-colour flow cytometry protocol.

scientific article

Protamine stimulates platelet aggregation in vitro with activation of the fibrinogen receptor and alpha-granule release, but impairs secondary activation via ADP and thrombin receptors

scientific article published on 28 January 2020

Protease-activated receptor 4 is more important than protease-activated receptor 1 for the thrombin-induced procoagulant effect on platelets

scientific article published on 11 July 2016

Response: platelets do not generate activated factor XII--how inappropriate experimental models have led to misleading conclusions.

scientific article published on September 2014

Responsiveness of platelets during storage studied with flow cytometry--formation of platelet subpopulations and LAMP-1 as new markers for the platelet storage lesion

scientific article published on 21 September 2015

The neutrophil serine protease PR3 induces shape change of platelets via the Rho/Rho kinase and Ca(2+) signaling pathways.

scientific article

The relative importance of the ADP receptors, P2Y12 and P2Y1, in thrombin-induced platelet activation.

scientific article

The role of platelets in blood coagulation--effects of platelet agonists and GPIIb/IIIa inhibitors studied by free oscillation rheometry

scientific article published on 01 January 2002

The role of thrombin receptors PAR1 and PAR4 for PAI-1 storage, synthesis and secretion by human platelets

scientific article published on 26 January 2012

Thrombin-induced lysosomal exocytosis in human platelets is dependent on secondary activation by ADP and regulated by endothelial-derived substances

scientific article published on 13 May 2015

Thrombin-induced platelet activation via PAR4: pivotal role for exosite II

scientific article published on 03 July 2014

Varying effects of tyrosine kinase inhibitors on platelet function-A need for individualized CML treatment to minimize the risk for hemostatic and thrombotic complications?

scientific article published on 12 November 2019

List of works by Sofia Ramström

A cluster of aspartic residues in the extracellular loop II of PAR 4 is important for thrombin interaction and activation of platelets

Adrenaline Improves Platelet Reactivity in Ticagrelor-Treated Healthy Volunteers

Adrenaline enhances in vitro platelet activation and aggregation in blood samples from ticagrelor-treated patients

Annexin V binding to platelets is agonist, time and temperature dependent.

Arachidonic acid causes lysis of blood cells and ADP-dependent platelet activation responses in platelet function tests

Assays of different aspects of haemostasis - what do they measure?

Better platelet function, less fibrinolysis and less hemolysis in re-transfused residual pump blood with the Ringer's chase technique - a randomized pilot study.

Caveats in studies of the physiological role of polyphosphates in coagulation

Clotting time analysis of citrated blood samples is strongly affected by the tube used for blood sampling

Clotting time by free oscillation rheometry and visual inspection and a viscoelastic description of the clotting phenomenon ⬇️

Comparative analysis of obesity-related cardiometabolic and renal biomarkers in human plasma and serum

Contact activation: important to consider when measuring the contribution of tissue factor-bearing microparticles to thrombin generation using phospholipid-containing reagents.

Detection of Lysosomal Exocytosis in Platelets by Flow Cytometry

Effects of inhibition of P2Y(1) and P2Y(12) on whole blood clotting, coagulum elasticity and fibrinolysis resistance studied with free oscillation rheometry.

Flow cytometry-based platelet function testing is predictive of symptom burden in a cohort of bleeders.

Free oscillation rheometry detects changes in clot properties in pregnancy and thrombocytopenia

Gradient-dependent inhibition of stimulatory signaling from platelet G protein-coupled receptors

Identification of low-density platelet populations with increased reactivity and elevated alpha-granule content.

Increased Thrombopoiesis and Platelet Activation in Hantavirus-Infected Patients

Lipoxin A₄ inhibits porphyromonas gingivalis-induced aggregation and reactive oxygen species production by modulating neutrophil-platelet interaction and CD11b expression

Methods for evaluation of platelet function

PO-55 - Individual variation in hemostatic alterations caused by tyrosine kinase inhibitors - a way to improve personalized cancer therapy?

Platelet Function Determined by Flow Cytometry: New Perspectives?

Platelet PAR1 receptor density--correlation to platelet activation response and changes in exposure after platelet activation

Platelet activation via PAR4 is involved in the initiation of thrombin generation and in clot elasticity development

Platelet adhesion changes during storage studied with a novel method using flow cytometry and protein-coated beads.

Platelet function testing at low platelet counts: When can you trust your analysis?

Platelet phosphatidylserine exposure and procoagulant activity in clotting whole blood--different effects of collagen, TRAP and calcium ionophore A23187.

Platelet subpopulations remain despite strong dual agonist stimulation and can be characterised using a novel six-colour flow cytometry protocol.

Protamine stimulates platelet aggregation in vitro with activation of the fibrinogen receptor and alpha-granule release, but impairs secondary activation via ADP and thrombin receptors

Protease-activated receptor 4 is more important than protease-activated receptor 1 for the thrombin-induced procoagulant effect on platelets

Response: platelets do not generate activated factor XII--how inappropriate experimental models have led to misleading conclusions.

Responsiveness of platelets during storage studied with flow cytometry--formation of platelet subpopulations and LAMP-1 as new markers for the platelet storage lesion

The neutrophil serine protease PR3 induces shape change of platelets via the Rho/Rho kinase and Ca(2+) signaling pathways.

The relative importance of the ADP receptors, P2Y12 and P2Y1, in thrombin-induced platelet activation.

The role of platelets in blood coagulation--effects of platelet agonists and GPIIb/IIIa inhibitors studied by free oscillation rheometry

The role of thrombin receptors PAR1 and PAR4 for PAI-1 storage, synthesis and secretion by human platelets

Thrombin-induced lysosomal exocytosis in human platelets is dependent on secondary activation by ADP and regulated by endothelial-derived substances

Thrombin-induced platelet activation via PAR4: pivotal role for exosite II

Varying effects of tyrosine kinase inhibitors on platelet function-A need for individualized CML treatment to minimize the risk for hemostatic and thrombotic complications?