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List of works by Daniel Mertens

A novel paradigm to trigger apoptosis in chronic lymphocytic leukemia

scientific article

Ala228 variant of trail receptor 1 affecting the ligand binding site is associated with chronic lymphocytic leukemia, mantle cell lymphoma, prostate cancer, head and neck squamous cell carcinoma and bladder cancer

B-cell neoplasia associated gene with multiple splicing (BCMS): the candidate B-CLL gene on 13q14 comprises more than 560 kb covering all critical regions

scientific article (publication date: June 2001)

BCL10 is not the gene inactivated by mutation in the 1p22 deletion region in mantle cell lymphoma

scientific article published on 01 August 2000

BCMSUN, a candidate gene for B-cell chronic lymphocytic leukemia and mantle-cell lymphoma, has an independently expressed homolog on 1p22-p31, BCMSUN-like.

scientific article

Biological diversity and risk-adapted treatment of chronic lymphocytic leukemia ⬇️

scientific article published on September 1, 2010

Blocking distinct interactions between Glioblastoma cells and their tissue microenvironment: A novel multi-targeted therapeutic approach

scientific article published on 3 April 2018

CLL and deletion 13q14: merely the miRs?

scientific article published on 01 March 2012

Chronic lymphocytic leukemia - genomics lead the way ⬇️

scientific article published on October 1, 2011

Chronic lymphocytic leukemia and 13q14: miRs and more

scientific article

Circulating microRNAs in hematological diseases: principles, challenges, and perspectives

scientific article

Comprehensive microRNA expression profiling in cerebrospinal fluid distinguishes between neurological disease classes

scientific article

DNA damage-induced transcriptional program in CLL: biological and diagnostic implications for functional p53 testing.

scientific article

DNA methylation dynamics during B cell maturation underlie a continuum of disease phenotypes in chronic lymphocytic leukemia

scientific article published on 18 January 2016

DNA methylation of chronic lymphocytic leukemia with differential response to chemotherapy

scientific article published on 01 May 2020

Detailed analysis of p53 pathway defects in fludarabine-refractory chronic lymphocytic leukemia (CLL): dissecting the contribution of 17p deletion, TP53 mutation, p53-p21 dysfunction, and miR34a in a prospective clinical trial.

scientific article published on 30 July 2009

Distinct gene expression patterns in chronic lymphocytic leukemia defined by usage of specific VH genes

scientific article

Epigenetic upregulation of lncRNAs at 13q14.3 in leukemia is linked to the In Cis downregulation of a gene cluster that targets NF-kB.

scientific article

Evidence for distinct pathomechanisms in genetic subgroups of chronic lymphocytic leukemia revealed by quantitative expression analysis of cell cycle, activation, and apoptosis-associated genes

scientific article published on 02 May 2005

Expression analysis of imbalanced genes in prostate carcinoma using tissue microarrays.

scientific article published on 5 December 2006

FBXW7 mutations reduce binding of NOTCH1, leading to cleaved NOTCH1 accumulation and target gene activation in CLL

scientific article published on 03 December 2018

Frequent amplifications and abundant expression of TRIO, NKD2, and IRX2 in soft tissue sarcomas

scientific article

From pathogenesis to treatment of chronic lymphocytic leukaemia

scientific article published on 03 December 2009

Genetics of Chronic Lymphocytic Leukemia ⬇️

scientific article published on November 17, 2011

Germline allele-specific expression of DAPK1 in chronic lymphocytic leukemia

scientific article

High-resolution genomic profiling of chronic lymphocytic leukemia reveals new recurrent genomic alterations

Ibrutinib-resistant CLL: unwanted and unwonted!

scientific article

Immune modulatory agents in hematopoietic malignancies ⬇️

scientific article published on 08 June 2011

Impact of serum storage conditions on microRNA stability

scientific article published on 16 April 2012

Importance of genetics in chronic lymphocytic leukemia ⬇️

scientific article published on March 23, 2011

In vivo processing assay based on a dual-luciferase reporter system to evaluate DROSHA enzymatic activity.

scientific article

In-vivo quantification of primary microRNA processing by Drosha with a luciferase based system

scientific article published on 23 February 2011

Linking aberrant chromatin features in chronic lymphocytic leukemia to transcription factor networks

scientific article published on 22 May 2019

Loss of cooperativity of secreted CD40L and increased dose-response to IL4 on CLL cell viability correlates with enhanced activation of NF-kB and STAT6

scientific article published on 27 May 2014

Missing the notch in NOTCH1

scientific article published on 16 February 2013

Moving from prognostic to predictive factors in chronic lymphocytic leukaemia (CLL).

scientific article published on March 2010

Mutations driving CLL and their evolution in progression and relapse

scientific article published on 14 October 2015

NOTCH1, SF3B1, and TP53 mutations in fludarabine-refractory CLL patients treated with alemtuzumab: results from the CLL2H trial of the GCLLSG.

scientific article published on 2 July 2013

Non-malignant B cells and chronic lymphocytic leukemia cells induce a pro-survival phenotype in CD14+ cells from peripheral blood

scientific article published on 18 January 2011

Nurse-like cells show deregulated expression of genes involved in immunocompetence

scientific article published on 25 May 2011

Off-target effects of siRNA specific for GFP

scientific article

Oxidative stress as candidate therapeutic target to overcome microenvironmental protection of CLL

scientific article published on 12 July 2019

Prognostic and predictive factors in patients with chronic lymphocytic leukemia: relevant in the era of novel treatment approaches?

scientific article published on 10 February 2014

Programmed death-1 and its ligand are novel immunotolerant molecules expressed on leukemic B cells in chronic lymphocytic leukemia

scientific article

Quantitative DNA methylation analysis identifies a single CpG dinucleotide important for ZAP-70 expression and predictive of prognosis in chronic lymphocytic leukemia

scientific article

Rapid detection of ATM/p53 function with p27Kip FACS analysis: a novel diagnostic tool for chronic lympocytic leukemia?

scientific article published on 22 August 2016

Reduced expression of CAMTA1 correlates with adverse outcome in neuroblastoma patients

scientific article

SYK carries no activating point mutations in patients with chronic lymphocytic leukaemia (CLL).

scientific article

TCL1A and ATM are co-expressed in chronic lymphocytic leukemia cells without deletion of 11q ⬇️

scientific article published on August 8, 2012

Targeting inhibitor of apoptosis proteins by Smac mimetic elicits cell death in poor prognostic subgroups of chronic lymphocytic leukemia

scientific article published on 20 June 2015

Telomere length in mantle cell lymphoma

scientific article published on 14 December 2012

The candidate immunotherapeutical target, the receptor for hyaluronic acid-mediated motility, is associated with proliferation and shows prognostic value in B-cell chronic lymphocytic leukemia.

scientific article published on 18 December 2008

Toward chemotherapy-free treatment of CLL

scientific article published on 01 September 2011

miR-34a as part of the resistance network in chronic lymphocytic leukemia

scientific article published on 21 October 2008

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