List of works - Sofia Avnet

A novel biomaterial for osteotropic drug nanocarriers: synthesis and biocompatibility evaluation of a PLGA-ALE conjugate

scientific article

Altered pH gradient at the plasma membrane of osteosarcoma cells is a key mechanism of drug resistance.

scientific article published on 22 August 2016

Annual Meeting of the International Society of Cancer Metabolism (ISCaM): Cancer Metabolism

scientific article published on 03 October 2018

Annual Meeting of the International Society of Cancer Metabolism (ISCaM): Metabolic Networks in Cancer

scientific article

Background and rationale of platelet gel in orthopaedic surgery

scientific article

Biocompatibility of poly(D,L-lactide-co-glycolide) nanoparticles conjugated with alendronate

scientific article

Cancer-associated mesenchymal stroma fosters the stemness of osteosarcoma cells in response to intratumoral acidosis via NF-κB activation

scientific article published on 26 November 2016

Carbonic anhydrase IX inhibition is an effective strategy for osteosarcoma treatment

scientific article published on 10 September 2015

Cause and effect of microenvironmental acidosis on bone metastases

scientific article published on 01 June 2019

Effects of antisense mediated inhibition of cathepsin K on human osteoclasts obtained from peripheral blood

Effects of prelamin A processing inhibitors on the differentiation and activity of human osteoclasts

scientific article published in September 2008

Energy metabolism in osteoclast formation and activity

scientific article published on 30 August 2016

Exosome-like nanovesicles isolated from Citrus limon L. exert antioxidative effect

scientific article published on 01 January 2018

Expression of an IGF-I receptor dominant negative mutant induces apoptosis, inhibits tumorigenesis and enhances chemosensitivity in Ewing's sarcoma cells.

scientific article published on September 2002

Histogenetic characterization of giant cell tumor of bone

scientific article published on 10 June 2008

IGF2 derived from SH-SY5Y neuroblastoma cells induces the osteoclastogenesis of human monocytic precursors

Identification and Validation of Housekeeping Genes for Gene Expression Analysis of Cancer Stem Cells

scientific article published on 19 February 2016

Impairment of lysosomal activity as a therapeutic modality targeting cancer stem cells of embryonal rhabdomyosarcoma cell line RD.

scientific article

In vitro blockade of receptor activator of nuclear factor-kappaB ligand prevents osteoclastogenesis induced by neuroblastoma cells

article published in 2004

Insulin receptor isoform A and insulin-like growth factor II as additional treatment targets in human osteosarcoma.

scientific article

Insulin receptor isoforms are differently expressed during human osteoblastogenesis

scientific article

Intratumoral acidosis fosters cancer-induced bone pain through the activation of the mesenchymal tumor-associated stroma in bone metastasis from breast carcinoma

scientific article published on 13 April 2017

Low toxicity and unprecedented anti-osteoclast activity of a simple sulfur-containing gem-bisphosphonate: a comparative study

scientific article published on 11 May 2013

MDA-MB-231 breast cancer cells fuel osteoclast metabolism and activity: A new rationale for the pathogenesis of osteolytic bone metastases

scientific article published on 30 August 2017

MET overexpression turns human primary osteoblasts into osteosarcomas.

scientific article published on May 2006

Mesenchymal stroma: Role in osteosarcoma progression.

scientific article published on 31 July 2017

Molecular basis of osteoclastogenesis induced by osteoblasts exposed to wear particles

scientific article published in May 2005

New Advances in the Study of Bone Tumors: A Lesson From the 3D Environment

scientific article published on 26 June 2019

Novel histone deacetylase inhibitors induce growth arrest, apoptosis, and differentiation in sarcoma cancer stem cells

scientific article published on 30 April 2015

Oct-1 recruitment to the nuclear envelope in adult-onset autosomal dominant leukodystrophy

scientific article published on 20 December 2012

Osteoblasts from a mandibuloacral dysplasia patient induce human blood precursors to differentiate into active osteoclasts

scientific article published on 16 March 2011

Osteoclast differentiation from human blood precursors on biomimetic calcium-phosphate substrates

scientific article

Pathobiology and therapeutic implications of tumor acidosis

scientific article published on 28 December 2016

Photodynamic Surgery for Feline Injection-Site Sarcoma

scientific article published on 08 July 2019

Platelet-rich plasma impairs osteoclast generation from human precursors of peripheral blood

scientific article published on 01 June 2010

Potential role of tartrate-resistant acid phosphatase 5b (TRACP 5b) as a surrogate marker of late loosening in patients with total hip arthroplasty: a cohort study

scientific article published on 01 July 2010

Pre-clinical Models for Studying the Interaction Between Mesenchymal Stromal Cells and Cancer Cells and the Induction of Stemness

scientific article published on 30 April 2019

Prominent role of RAB39A-RXRB axis in cancer development and stemness.

scientific article

Proton channels and exchangers in cancer

scientific article

Proton pump inhibitor chemosensitization in human osteosarcoma: from the bench to the patients' bed

scientific article published on 24 October 2013

RAB39A: a Rab small GTPase with a prominent role in cancer stemness.

scientific article published on 10 April 2018

Role of Pericellular Matrix in the Regulation of Cancer Stemness

scientific article published on 19 May 2016

Sarcoma treatment in the era of molecular medicine

scientific article published on 13 October 2020

Sequence and TLR9 independent increase of TRACP expression by antisense DNA and siRNA molecules.

scientific article published on 6 June 2007

Sphere-forming cell subsets with cancer stem cell properties in human musculoskeletal sarcomas

scientific article published on May 2013

Spheroid-based 3D cell cultures identify salinomycin as a promising drug for the treatment of chondrosarcoma

article

Spontaneous formation of multinucleated giant cells with bone resorbing activity by long culture of human peripheral blood CD14-positive monocytes in vitro

scientific article published on 01 February 2010

Sustained autocrine induction and impaired negative feedback of osteoclastogenesis in CD14(+) cells of giant cell tumor of bone.

scientific article

Synthesis, characterization and biological activity of hydroxyl-bisphosphonic analogs of bile acids.

scientific article

The Effects of Systemic and Local Acidosis on Insulin Resistance and Signaling ⬇️

scientific article published on 30 December 2018

The Microfluidic Trainer: Design, Fabrication and Validation of a Tool for Testing and Improving Manual Skills

scientific article published on 19 September 2020

The Role of Autophagy in the Maintenance of Stemness and Differentiation of Mesenchymal Stem Cells

scientific article

The effect of extracellular acidosis on the behaviour of mesenchymal stem cells in vitro

scientific article

The effect of poly(d,l-lactide-co-glycolide)-alendronate conjugate nanoparticles on human osteoclast precursors.

scientific article published on 20 July 2011

The human tumor microbiome is composed of tumor type-specific intracellular bacteria

scientific article

The influence of alumina and ultra-high molecular weight polyethylene particles on osteoblast-osteoclast cooperation.

scientific article published in August 2004

The natural compound Alizarin as an osteotropic drug for the treatment of bone tumors

scientific article

Therapeutic implications of tumor interstitial acidification.

scientific article published on 7 February 2017

Tumor-Activated Mesenchymal Stromal Cells Promote Osteosarcoma Stemness and Migratory Potential via IL-6 Secretion.

scientific article

V-ATPase as an effective therapeutic target for sarcomas

scientific article published on January 2014

V-ATPase is a candidate therapeutic target for Ewing sarcoma

scientific article published on 8 April 2013

Validation of Suitable Housekeeping Genes for the Normalization of mRNA Expression for Studying Tumor Acidosis

article

List of works by Sofia Avnet

A novel biomaterial for osteotropic drug nanocarriers: synthesis and biocompatibility evaluation of a PLGA-ALE conjugate

Altered pH gradient at the plasma membrane of osteosarcoma cells is a key mechanism of drug resistance.

Annual Meeting of the International Society of Cancer Metabolism (ISCaM): Cancer Metabolism

Annual Meeting of the International Society of Cancer Metabolism (ISCaM): Metabolic Networks in Cancer

Background and rationale of platelet gel in orthopaedic surgery

Biocompatibility of poly(D,L-lactide-co-glycolide) nanoparticles conjugated with alendronate

Cancer-associated mesenchymal stroma fosters the stemness of osteosarcoma cells in response to intratumoral acidosis via NF-κB activation

Carbonic anhydrase IX inhibition is an effective strategy for osteosarcoma treatment

Cause and effect of microenvironmental acidosis on bone metastases

Effects of antisense mediated inhibition of cathepsin K on human osteoclasts obtained from peripheral blood

Effects of prelamin A processing inhibitors on the differentiation and activity of human osteoclasts

Energy metabolism in osteoclast formation and activity

Exosome-like nanovesicles isolated from Citrus limon L. exert antioxidative effect

Expression of an IGF-I receptor dominant negative mutant induces apoptosis, inhibits tumorigenesis and enhances chemosensitivity in Ewing's sarcoma cells.

Histogenetic characterization of giant cell tumor of bone

IGF2 derived from SH-SY5Y neuroblastoma cells induces the osteoclastogenesis of human monocytic precursors

Identification and Validation of Housekeeping Genes for Gene Expression Analysis of Cancer Stem Cells

Impairment of lysosomal activity as a therapeutic modality targeting cancer stem cells of embryonal rhabdomyosarcoma cell line RD.

In vitro blockade of receptor activator of nuclear factor-kappaB ligand prevents osteoclastogenesis induced by neuroblastoma cells

Insulin receptor isoform A and insulin-like growth factor II as additional treatment targets in human osteosarcoma.

Insulin receptor isoforms are differently expressed during human osteoblastogenesis

Intratumoral acidosis fosters cancer-induced bone pain through the activation of the mesenchymal tumor-associated stroma in bone metastasis from breast carcinoma

Low toxicity and unprecedented anti-osteoclast activity of a simple sulfur-containing gem-bisphosphonate: a comparative study

MDA-MB-231 breast cancer cells fuel osteoclast metabolism and activity: A new rationale for the pathogenesis of osteolytic bone metastases

MET overexpression turns human primary osteoblasts into osteosarcomas.

Mesenchymal stroma: Role in osteosarcoma progression.

Molecular basis of osteoclastogenesis induced by osteoblasts exposed to wear particles

New Advances in the Study of Bone Tumors: A Lesson From the 3D Environment

Novel histone deacetylase inhibitors induce growth arrest, apoptosis, and differentiation in sarcoma cancer stem cells

Oct-1 recruitment to the nuclear envelope in adult-onset autosomal dominant leukodystrophy

Osteoblasts from a mandibuloacral dysplasia patient induce human blood precursors to differentiate into active osteoclasts

Osteoclast differentiation from human blood precursors on biomimetic calcium-phosphate substrates

Pathobiology and therapeutic implications of tumor acidosis

Photodynamic Surgery for Feline Injection-Site Sarcoma

Platelet-rich plasma impairs osteoclast generation from human precursors of peripheral blood

Potential role of tartrate-resistant acid phosphatase 5b (TRACP 5b) as a surrogate marker of late loosening in patients with total hip arthroplasty: a cohort study

Pre-clinical Models for Studying the Interaction Between Mesenchymal Stromal Cells and Cancer Cells and the Induction of Stemness

Prominent role of RAB39A-RXRB axis in cancer development and stemness.

Proton channels and exchangers in cancer

Proton pump inhibitor chemosensitization in human osteosarcoma: from the bench to the patients' bed

RAB39A: a Rab small GTPase with a prominent role in cancer stemness.

Role of Pericellular Matrix in the Regulation of Cancer Stemness

Sarcoma treatment in the era of molecular medicine

Sequence and TLR9 independent increase of TRACP expression by antisense DNA and siRNA molecules.

Sphere-forming cell subsets with cancer stem cell properties in human musculoskeletal sarcomas

Spheroid-based 3D cell cultures identify salinomycin as a promising drug for the treatment of chondrosarcoma

Spontaneous formation of multinucleated giant cells with bone resorbing activity by long culture of human peripheral blood CD14-positive monocytes in vitro

Sustained autocrine induction and impaired negative feedback of osteoclastogenesis in CD14(+) cells of giant cell tumor of bone.

Synthesis, characterization and biological activity of hydroxyl-bisphosphonic analogs of bile acids.

The Effects of Systemic and Local Acidosis on Insulin Resistance and Signaling ⬇️

The Microfluidic Trainer: Design, Fabrication and Validation of a Tool for Testing and Improving Manual Skills

The Role of Autophagy in the Maintenance of Stemness and Differentiation of Mesenchymal Stem Cells

The effect of extracellular acidosis on the behaviour of mesenchymal stem cells in vitro

The effect of poly(d,l-lactide-co-glycolide)-alendronate conjugate nanoparticles on human osteoclast precursors.

The human tumor microbiome is composed of tumor type-specific intracellular bacteria

The influence of alumina and ultra-high molecular weight polyethylene particles on osteoblast-osteoclast cooperation.

The natural compound Alizarin as an osteotropic drug for the treatment of bone tumors

Therapeutic implications of tumor interstitial acidification.

Tumor-Activated Mesenchymal Stromal Cells Promote Osteosarcoma Stemness and Migratory Potential via IL-6 Secretion.

V-ATPase as an effective therapeutic target for sarcomas

V-ATPase is a candidate therapeutic target for Ewing sarcoma

Validation of Suitable Housekeeping Genes for the Normalization of mRNA Expression for Studying Tumor Acidosis