List of works - Philippe Rochaix

"Sugar" tumor of the pancreas: a rare entity that is diagnosable on preoperative fine-needle biopsies.

scientific article published on 9 April 2005

Adenoid cystic carcinoma of the lung: interest of 18FDG PET/CT in the management of an atypical presentation.

scientific article

An alternative fixative to formalin fixation for molecular applications: the RCL2(®)-CS100 approach.

scientific article published on January 2011

Assessment of epidermal growth factor receptor (EGFR) expression in primary colorectal carcinomas and their related metastases on tissue sections and tissue microarray

scientific article

Blocking Tumor Necrosis Factor α Enhances CD8 T-cell-Dependent Immunity in Experimental Melanoma

scientific article published on 14 May 2015

Breast implant-associated anaplastic large cell lymphoma: two distinct clinicopathological variants with different outcomes.

scientific article

Breslow thickness, clark index and ulceration are associated with sentinel lymph node metastasis in melanoma patients: a cohort analysis of 612 patients.

scientific article published on 26 August 2014

CTNNB1 mutation analysis is a useful tool for the diagnosis of desmoid tumors: a study of 260 desmoid tumors and 191 potential morphologic mimics

scientific article published on 06 July 2012

Cetuximab potentiates oxaliplatin cytotoxic effect through a defect in NER and DNA replication initiation

scientific article published on 8 January 2008

Childhood anaplastic large cell lymphoma Ki-1/CD30: clinicopathologic features of 19 cases.

scientific article published on January 1994

Dual Relief of T-Lymphocyte Proliferation and Effector Function Underlies Response to PD-1 Blockade in Epithelial Malignancies

scientific article published on 15 April 2020

Dual role of sphingosine kinase-1 in promoting the differentiation of dermal fibroblasts and the dissemination of melanoma cells

scientific article

Evaluation of eight melanocytic and neural crest-associated markers in a well-characterised series of 124 malignant peripheral nerve sheath tumours (MPNST): useful to distinguish MPNST from melanoma?

scientific article published on 23 October 2018

Ex Vivo Discrimination between Normal and Pathological Tissues in Human Breast Surgical Biopsies Using Bioimpedance Spectroscopy

scientific article published on 01 April 1999

Gene expression profiling of human melanoma cell lines with distinct metastatic potential identifies new progression markers.

scientific article published on September 2007

Gene expression profiling on pre- and post-erlotinib tumors from patients with head and neck squamous cell carcinoma

scientific article published on 13 July 2012

Gene therapy for pancreatic carcinoma: local and distant antitumor effects after somatostatin receptor sst2 gene transfer

scientific article published on April 1999

High endothelial venule blood vessels for tumor-infiltrating lymphocytes are associated with lymphotoxin β-producing dendritic cells in human breast cancer

scientific article

High endothelial venules (HEVs) in human melanoma lesions: Major gateways for tumor-infiltrating lymphocytes

scientific article

High incidence of Epstein-Barr virus detection in Hodgkin's disease and absence of detection in anaplastic large-cell lymphoma in children.

scientific article published in August 1993

Highly Concordant Results Between Immunohistochemistry and Molecular Testing of Mutated V600E BRAF in Primary and Metastatic Melanoma.

scientific article published in June 2016

Histological regression in primary melanoma: not a predictor of sentinel lymph node metastasis in a cohort of 397 patients

scientific article published on 21 December 2009

Human solid tumors contain high endothelial venules: association with T- and B-lymphocyte infiltration and favorable prognosis in breast cancer.

scientific article published on 16 August 2011

Identification of a new panel of serum autoantibodies associated with the presence of in situ carcinoma of the breast in younger women.

scientific article published on 7 July 2009

Identification of a tumor-promoter cholesterol metabolite in human breast cancers acting through the glucocorticoid receptor

scientific article

Identification of biomarkers of human pancreatic adenocarcinomas by expression profiling and validation with gene expression analysis in endoscopic ultrasound-guided fine needle aspiration samples

scientific article published on June 2006

Immunohistochemistry for Diagnosis of Metastatic Carcinomas of Unknown Primary Site.

scientific article published on 5 April 2018

In practice for the pathologist: practical and technical limitations ⬇️

scientific article published on September 28, 2011

In vivo Effects in Melanoma of ROCK Inhibition-Induced FasL Overexpression.

scientific article published on 14 July 2015

In vivo and in vitro antitumor activity of oxaliplatin in combination with cetuximab in human colorectal tumor cell lines expressing different level of EGFR.

scientific article published on December 2005

In vivo patterns of Bcl-2 family protein expression in breast carcinomas in relation to apoptosis

scientific article published on 01 March 1999

Increased expression of a COOH-truncated nucleophosmin resulting from alternative splicing is associated with cellular resistance to ionizing radiation in HeLa cells.

scientific article published in August 2002

Indium-111–Pentetreotide Scintigraphy and Somatostatin Receptor Subtype 2 Expression: New Prognostic Factors for Malignant Well-Differentiated Endocrine Tumors

scientific article published on 01 February 2008

Inhibition of Rho pathways induces radiosensitization and oxygenation in human glioblastoma xenografts.

scientific article published on December 2003

Inhibition of growth and metastatic progression of pancreatic carcinoma in hamster after somatostatin receptor subtype 2 (sst2) gene expression and administration of cytotoxic somatostatin analog AN-238.

scientific article published in August 2000

Intraoperative testosterone assay for virilizing ovarian tumor topographic assessment: report of a Leydig cell tumor of the ovary in a premenopausal woman with an adrenal incidentaloma.

scientific article published in July 2002

Is there an immunohistochemical technique definitively valid in epidermal growth factor receptor assessment?

scientific article published in December 2006

KBA.62: a useful marker for primary and metastatic melanomas.

scientific article published on 20 May 2008

Melanoma cells treated with GGTI and IFN-gamma allow murine vaccination and enhance cytotoxic response against human melanoma cells

scientific article

Melanoma-expressed CD70 is involved in invasion and metastasis.

scientific article

Molecular diagnosis of unknown primary tumors ⬇️

scientific article published on August 21, 2010

Morphological analyses of paraspinal muscles: comparison of progressive lumbar kyphosis (camptocormia) and narrowing of lumbar canal by disc protrusions

scientific article published on 01 September 1993

Novel synergistic mechanism for sst2 somatostatin and TNFalpha receptors to induce apoptosis: crosstalk between NF-kappaB and JNK pathways.

scientific article published on 28 April 2006

Octreotide in insulinoma patients: efficacy on hypoglycemia, relationships with Octreoscan scintigraphy and immunostaining with anti-sst2A and anti-sst5 antibodies.

scientific article published in May 2005

PNL2, a new monoclonal antibody directed against a fixative-resistant melanocyte antigen.

scientific article published on May 2003

Pilot study of neoadjuvant treatment with erlotinib in nonmetastatic head and neck squamous cell carcinoma.

scientific article

Place de la radiothérapie dans le traitement conservateur des sarcomes en territoire irradié

scientific article published on 18 April 2014

Population pharmacokinetics of erlotinib and its pharmacokinetic/pharmacodynamic relationships in head and neck squamous cell carcinoma.

scientific article

Preclinical and clinical evidence that Deoxy-2-[18F]fluoro-D-glucose positron emission tomography with computed tomography is a reliable tool for the detection of early molecular responses to erlotinib in head and neck cancer

scientific article published on 26 July 2010

Preclinical toxicity, toxicokinetics, and antitumoral efficacy studies of DTS-201, a tumor-selective peptidic prodrug of doxorubicin.

scientific article published on February 2008

Preferential cytoplasmic localization of p34cdc2 in recurrent human squamous cell carcinoma after radiotherapy

scientific article published on 01 March 1997

Prenylation inhibitors stimulate both estrogen receptor alpha transcriptional activity through AF-1 and AF-2 and estrogen receptor beta transcriptional activity.

scientific article

Proteomic analysis of RCL2 paraffin-embedded tissues.

scientific article

RCL2, a new fixative, preserves morphology and nucleic acid integrity in paraffin-embedded breast carcinoma and microdissected breast tumor cells.

scientific article

RREB1-MKL2 fusion in biphenotypic "oropharyngeal" sarcoma: New entity or part of the spectrum of biphenotypic sinonasal sarcomas?

scientific article published on 20 December 2017

Reduced expression of retinoic acid receptor beta protein (RAR beta) in human papillary thyroid carcinoma: immunohistochemical and western blot study

scientific article published on 01 October 1998

Relation of follicular dendritic reticulum cells to Reed-Sternberg cells of Hodgkin's disease with emphasis on the expression of CD21 antigen.

scientific article published on June 1993

Resistance of melanoma to immune checkpoint inhibitors is overcome by targeting the sphingosine kinase-1

scientific article published on 23 January 2020

Role of radiation therapy in the conservative management of sarcoma within an irradiated field

scientific article published on 26 September 2013

Selective inhibition of HER2 inhibits AKT signal transduction and prolongs disease-free survival in a micrometastasis model of ovarian carcinoma

scientific article published on 11 October 2005

Signal transduction of somatostatin receptors negatively controlling cell proliferation.

scientific article

Somatostatin receptor subtype 2 sensitizes human pancreatic cancer cells to death ligand-induced apoptosis

scholarly article

Statins Reduce Melanoma Development and Metastasis through MICA Overexpression.

scientific article published on 13 March 2013

Stromal estrogen receptor-α promotes tumor growth by normalizing an increased angiogenesis.

scientific article

Structure of a human intramembrane ceramidase explains enzymatic dysfunction found in leukodystrophy

scientific article published in Nature Communications

TNFα blockade overcomes resistance to anti-PD-1 in experimental melanoma.

scientific article published on 22 December 2017

The AF-1 activation-function of ERalpha may be dispensable to mediate the effect of estradiol on endothelial NO production in mice

scientific article

The AF-1-deficient estrogen receptor ERα46 isoform is frequently expressed in human breast tumors

scientific article published on 07 December 2016

The expression of CD70 and CD80 by gene-modified tumor cells induces an antitumor response depending on the MHC status

scientific article published in December 2000

The farnesyltransferase inhibitor R115777 reduces hypoxia and matrix metalloproteinase 2 expression in human glioma xenograft.

scientific article published in December 2003

The role of a bioresource research impact factor as an incentive to share human bioresources

scientific article published in June 2011

Thrombospondin-1 is a critical effector of oncosuppressive activity of sst2 somatostatin receptor on pancreatic cancer

scientific article published on October 2009

Trastuzumab induced in vivo tissue remodelling associated in vitro with inhibition of the active forms of AKT and PTEN and RhoB induction in an ovarian carcinoma model.

scientific article

Treatment of murine hepatocellular carcinoma using genetically modified cells to express interleukin-12.

scientific article published on April 2004

Tumour lysis syndrome: an unexpected adverse event associated with ipilimumab

scientific article published on 3 June 2016

Two antiestrogens affect differently chromatin remodeling of trefoil factor 1 (pS2) gene and the fate of estrogen receptor in MCF7 cells

scientific article published in October 2002

Use and comparison of different internal ribosomal entry sites (IRES) in tricistronic retroviral vectors

scientific article

Validation of the Complexity INdex in SARComas prognostic signature on formalin-fixed, paraffin-embedded, soft-tissue sarcomas

scientific article published on 01 August 2018

Value of cytokeratin 5/6 immunostaining using D5/16 B4 antibody in the spectrum of proliferative intraepithelial lesions of the breast. A comparative study with 34betaE12 antibody.

scientific article published on 24 April 2003

[A novel fixed paraffin-embedded tissue processing for proteomic analysis]

scientific article published on 01 July 2008

[Carcinoma of unknown primary. Case no. 2]

scientific article published on 19 June 2018

[Carcinoma of unknown primary. Case no. 1]

scientific article published on 19 June 2018

[Carcinoma of unknown primary. Role of the pathologist in 2018: Introduction]

scientific article published on 19 June 2018

[EGFR expression in colorectal cancer and role in tumorigenesis]

scientific article published on 01 August 2005

[Granular cell tumors of the skin of nonneural origin: report of 8 cases]

scientific article published on 01 April 1999

[Malignant granular cell tumor. Report of a clinico-pathologic case]

scientific article published on 01 September 1996

[Of pathologists, tissues and fixatives]

scientific article published on 01 February 2006

List of works by Philippe Rochaix

"Sugar" tumor of the pancreas: a rare entity that is diagnosable on preoperative fine-needle biopsies.

Adenoid cystic carcinoma of the lung: interest of 18FDG PET/CT in the management of an atypical presentation.

An alternative fixative to formalin fixation for molecular applications: the RCL2(®)-CS100 approach.

Assessment of epidermal growth factor receptor (EGFR) expression in primary colorectal carcinomas and their related metastases on tissue sections and tissue microarray

Blocking Tumor Necrosis Factor α Enhances CD8 T-cell-Dependent Immunity in Experimental Melanoma

Breast implant-associated anaplastic large cell lymphoma: two distinct clinicopathological variants with different outcomes.

Breslow thickness, clark index and ulceration are associated with sentinel lymph node metastasis in melanoma patients: a cohort analysis of 612 patients.

CTNNB1 mutation analysis is a useful tool for the diagnosis of desmoid tumors: a study of 260 desmoid tumors and 191 potential morphologic mimics

Cetuximab potentiates oxaliplatin cytotoxic effect through a defect in NER and DNA replication initiation

Childhood anaplastic large cell lymphoma Ki-1/CD30: clinicopathologic features of 19 cases.

Dual Relief of T-Lymphocyte Proliferation and Effector Function Underlies Response to PD-1 Blockade in Epithelial Malignancies

Dual role of sphingosine kinase-1 in promoting the differentiation of dermal fibroblasts and the dissemination of melanoma cells

Evaluation of eight melanocytic and neural crest-associated markers in a well-characterised series of 124 malignant peripheral nerve sheath tumours (MPNST): useful to distinguish MPNST from melanoma?

Ex Vivo Discrimination between Normal and Pathological Tissues in Human Breast Surgical Biopsies Using Bioimpedance Spectroscopy

Gene expression profiling of human melanoma cell lines with distinct metastatic potential identifies new progression markers.

Gene expression profiling on pre- and post-erlotinib tumors from patients with head and neck squamous cell carcinoma

Gene therapy for pancreatic carcinoma: local and distant antitumor effects after somatostatin receptor sst2 gene transfer

High endothelial venule blood vessels for tumor-infiltrating lymphocytes are associated with lymphotoxin β-producing dendritic cells in human breast cancer

High endothelial venules (HEVs) in human melanoma lesions: Major gateways for tumor-infiltrating lymphocytes

High incidence of Epstein-Barr virus detection in Hodgkin's disease and absence of detection in anaplastic large-cell lymphoma in children.

Highly Concordant Results Between Immunohistochemistry and Molecular Testing of Mutated V600E BRAF in Primary and Metastatic Melanoma.

Histological regression in primary melanoma: not a predictor of sentinel lymph node metastasis in a cohort of 397 patients

Human solid tumors contain high endothelial venules: association with T- and B-lymphocyte infiltration and favorable prognosis in breast cancer.

Identification of a new panel of serum autoantibodies associated with the presence of in situ carcinoma of the breast in younger women.

Identification of a tumor-promoter cholesterol metabolite in human breast cancers acting through the glucocorticoid receptor

Identification of biomarkers of human pancreatic adenocarcinomas by expression profiling and validation with gene expression analysis in endoscopic ultrasound-guided fine needle aspiration samples

Immunohistochemistry for Diagnosis of Metastatic Carcinomas of Unknown Primary Site.

In practice for the pathologist: practical and technical limitations ⬇️

In vivo Effects in Melanoma of ROCK Inhibition-Induced FasL Overexpression.

In vivo and in vitro antitumor activity of oxaliplatin in combination with cetuximab in human colorectal tumor cell lines expressing different level of EGFR.

In vivo patterns of Bcl-2 family protein expression in breast carcinomas in relation to apoptosis

Increased expression of a COOH-truncated nucleophosmin resulting from alternative splicing is associated with cellular resistance to ionizing radiation in HeLa cells.

Indium-111–Pentetreotide Scintigraphy and Somatostatin Receptor Subtype 2 Expression: New Prognostic Factors for Malignant Well-Differentiated Endocrine Tumors

Inhibition of Rho pathways induces radiosensitization and oxygenation in human glioblastoma xenografts.

Inhibition of growth and metastatic progression of pancreatic carcinoma in hamster after somatostatin receptor subtype 2 (sst2) gene expression and administration of cytotoxic somatostatin analog AN-238.

Intraoperative testosterone assay for virilizing ovarian tumor topographic assessment: report of a Leydig cell tumor of the ovary in a premenopausal woman with an adrenal incidentaloma.

Is there an immunohistochemical technique definitively valid in epidermal growth factor receptor assessment?

KBA.62: a useful marker for primary and metastatic melanomas.

Melanoma cells treated with GGTI and IFN-gamma allow murine vaccination and enhance cytotoxic response against human melanoma cells

Melanoma-expressed CD70 is involved in invasion and metastasis.

Molecular diagnosis of unknown primary tumors ⬇️

Morphological analyses of paraspinal muscles: comparison of progressive lumbar kyphosis (camptocormia) and narrowing of lumbar canal by disc protrusions

Novel synergistic mechanism for sst2 somatostatin and TNFalpha receptors to induce apoptosis: crosstalk between NF-kappaB and JNK pathways.

Octreotide in insulinoma patients: efficacy on hypoglycemia, relationships with Octreoscan scintigraphy and immunostaining with anti-sst2A and anti-sst5 antibodies.

PNL2, a new monoclonal antibody directed against a fixative-resistant melanocyte antigen.

Pilot study of neoadjuvant treatment with erlotinib in nonmetastatic head and neck squamous cell carcinoma.

Place de la radiothérapie dans le traitement conservateur des sarcomes en territoire irradié

Population pharmacokinetics of erlotinib and its pharmacokinetic/pharmacodynamic relationships in head and neck squamous cell carcinoma.

Preclinical and clinical evidence that Deoxy-2-[18F]fluoro-D-glucose positron emission tomography with computed tomography is a reliable tool for the detection of early molecular responses to erlotinib in head and neck cancer

Preclinical toxicity, toxicokinetics, and antitumoral efficacy studies of DTS-201, a tumor-selective peptidic prodrug of doxorubicin.

Preferential cytoplasmic localization of p34cdc2 in recurrent human squamous cell carcinoma after radiotherapy

Prenylation inhibitors stimulate both estrogen receptor alpha transcriptional activity through AF-1 and AF-2 and estrogen receptor beta transcriptional activity.

Proteomic analysis of RCL2 paraffin-embedded tissues.

RCL2, a new fixative, preserves morphology and nucleic acid integrity in paraffin-embedded breast carcinoma and microdissected breast tumor cells.

RREB1-MKL2 fusion in biphenotypic "oropharyngeal" sarcoma: New entity or part of the spectrum of biphenotypic sinonasal sarcomas?

Reduced expression of retinoic acid receptor beta protein (RAR beta) in human papillary thyroid carcinoma: immunohistochemical and western blot study

Relation of follicular dendritic reticulum cells to Reed-Sternberg cells of Hodgkin's disease with emphasis on the expression of CD21 antigen.

Resistance of melanoma to immune checkpoint inhibitors is overcome by targeting the sphingosine kinase-1

Role of radiation therapy in the conservative management of sarcoma within an irradiated field

Selective inhibition of HER2 inhibits AKT signal transduction and prolongs disease-free survival in a micrometastasis model of ovarian carcinoma

Signal transduction of somatostatin receptors negatively controlling cell proliferation.

Somatostatin receptor subtype 2 sensitizes human pancreatic cancer cells to death ligand-induced apoptosis

Statins Reduce Melanoma Development and Metastasis through MICA Overexpression.

Stromal estrogen receptor-α promotes tumor growth by normalizing an increased angiogenesis.

Structure of a human intramembrane ceramidase explains enzymatic dysfunction found in leukodystrophy

TNFα blockade overcomes resistance to anti-PD-1 in experimental melanoma.

The AF-1 activation-function of ERalpha may be dispensable to mediate the effect of estradiol on endothelial NO production in mice

The AF-1-deficient estrogen receptor ERα46 isoform is frequently expressed in human breast tumors

The expression of CD70 and CD80 by gene-modified tumor cells induces an antitumor response depending on the MHC status

The farnesyltransferase inhibitor R115777 reduces hypoxia and matrix metalloproteinase 2 expression in human glioma xenograft.

The role of a bioresource research impact factor as an incentive to share human bioresources

Thrombospondin-1 is a critical effector of oncosuppressive activity of sst2 somatostatin receptor on pancreatic cancer

Trastuzumab induced in vivo tissue remodelling associated in vitro with inhibition of the active forms of AKT and PTEN and RhoB induction in an ovarian carcinoma model.

Treatment of murine hepatocellular carcinoma using genetically modified cells to express interleukin-12.

Tumour lysis syndrome: an unexpected adverse event associated with ipilimumab

Two antiestrogens affect differently chromatin remodeling of trefoil factor 1 (pS2) gene and the fate of estrogen receptor in MCF7 cells

Use and comparison of different internal ribosomal entry sites (IRES) in tricistronic retroviral vectors

Validation of the Complexity INdex in SARComas prognostic signature on formalin-fixed, paraffin-embedded, soft-tissue sarcomas

Value of cytokeratin 5/6 immunostaining using D5/16 B4 antibody in the spectrum of proliferative intraepithelial lesions of the breast. A comparative study with 34betaE12 antibody.