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List of works by Malgorzata Wygrecka

Alveolar oxidative stress is associated with elevated levels of nonenzymatic low-molecular-weight antioxidants in patients with different forms of chronic fibrosing interstitial lung diseases

scientific article

Amplified canonical transforming growth factor-β signalling via heat shock protein 90 in pulmonary fibrosis

scientific article published on 19 December 2016

Antihistone Properties of C1 Esterase Inhibitor Protect against Lung Injury

scientific article published on 22 December 2016

BDNF/TrkB signaling augments smooth muscle cell proliferation in pulmonary hypertension

scientific article published on 8 October 2012

Biglycan evokes autophagy in macrophages via a novel CD44/Toll-like receptor 4 signaling axis in ischemia/reperfusion injury

scientific article published on 31 January 2019

Biglycan is a new high-affinity ligand for CD14 in macrophages

scientific article published on 17 May 2018

Biglycan, a novel trigger of Th1 and Th17 cell recruitment into the kidney

scientific article published on 15 December 2017

Biglycan- and Sphingosine Kinase-1 Signaling Crosstalk Regulates the Synthesis of Macrophage Chemoattractants.

scientific article published on 09 March 2017

Biomarkers in idiopathic pulmonary fibrosis.

scientific article published on 30 January 2018

Breaking down chronic inflammatory diseases: the role of biglycan in promoting a switch between inflammation and autophagy

scientific article published on 27 February 2019

Caspase-11 promotes allergic airway inflammation

scientific article published on 26 February 2020

Cellular origin of pro-coagulant and (anti)-fibrinolytic factors in bleomycin-injured lungs

scientific article published in March 2007

Characterization of dendritic cells in testicular draining lymph nodes in a rat model of experimental autoimmune orchitis

scientific article

Coagulation factor XII regulates inflammatory responses in human lungs.

scientific article published on 17 August 2017

Comparative proteomic analysis of lung tissue from patients with idiopathic pulmonary fibrosis (IPF) and lung transplant donor lungs

scientific article

Current view on alveolar coagulation and fibrinolysis in acute inflammatory and chronic interstitial lung diseases

scientific article published on 01 March 2008

Danger-Associated Molecular Patterns Derived From the Extracellular Matrix Provide Temporal Control of Innate Immunity.

scientific article published in November 2017

Disruption of platelet-derived chemokine heteromers prevents neutrophil extravasation in acute lung injury

scientific article published on 12 January 2012

Docking of Meprin α to Heparan Sulphate Protects the Endothelium from Inflammatory Cell Extravasation

scientific article published on 20 September 2018

Elevated protein arginine methyltransferase 1 expression regulates fibroblast motility in pulmonary fibrosis

scientific article published on 21 September 2015

Enolase-1 promotes plasminogen-mediated recruitment of monocytes to the acutely inflamed lung

scientific article published on 30 January 2009

FXII promotes proteolytic processing of the LRP1 ectodomain.

scientific article published on 25 May 2017

Factor XII in coagulation, inflammation and beyond

scientific article published on 15 August 2018

Fhl-1, a new key protein in pulmonary hypertension.

scientific article

From plasminogen to plasmin: role of plasminogen receptors in human cancer.

scientific article

Genetic Deficiency and Pharmacological Stabilization of Mast Cells Ameliorate Pressure Overload-Induced Maladaptive Right Ventricular Remodeling in Mice

scientific article published on 30 November 2020

Heparan sulfate proteoglycans mediate factor XIIa binding to the cell surface

scientific article

Histological characterization of mast cell chymase in patients with pulmonary hypertension and chronic obstructive pulmonary disease.

scientific article

Host-derived extracellular RNA promotes adhesion of Streptococcus pneumoniae to endothelial and epithelial cells

scientific article published on 28 November 2016

Host-derived extracellular nucleic acids enhance innate immune responses, induce coagulation, and prolong survival upon infection in insects.

scientific article published on August 2008

Hyperoxia modulates TGF-beta/BMP signaling in a mouse model of bronchopulmonary dysplasia

scientific article published on 27 October 2006

Hypoxia- or PDGF-BB-dependent paxillin tyrosine phosphorylation in pulmonary hypertension is reversed by HIF-1α depletion or imatinib treatment.

scientific article published on 18 September 2014

Inactivation of nuclear histone deacetylases by EP300 disrupts the MiCEE complex in idiopathic pulmonary fibrosis

scientific article published on 20 May 2019

Inhibition of PDGF-BB by Factor VII-activating protease (FSAP) is neutralized by protease nexin-1, and the FSAP-inhibitor complexes are internalized via LRP.

scientific article published on June 2007

Inhibition of Urokinase Activity Reduces Primary Tumor Growth and Metastasis Formation in a Murine Lung Carcinoma Model

scientific article published on 07 January 2010

LRP1: A chameleon receptor of lung inflammation and repair.

scientific article published on 17 December 2017

Loss of RAGE in pulmonary fibrosis: molecular relations to functional changes in pulmonary cell types

scientific article

Low density lipoprotein receptor-related protein 1 couples β1 integrin activation to degradation

scientific article published on 7 November 2017

Maggot excretion products from the blowfly Lucilia sericata contain contact phase/intrinsic pathway-like proteases with procoagulant functions.

scientific article published on 7 May 2015

Mast cell chymase: an indispensable instrument in the pathological symphony of idiopathic pulmonary fibrosis?

scientific article published on 25 February 2013

Mast cells and fibroblasts work in concert to aggravate pulmonary fibrosis: role of transmembrane SCF and the PAR-2/PKC-α/Raf-1/p44/42 signaling pathway

scientific article published on 4 April 2013

Meprin β contributes to collagen deposition in lung fibrosis

scientific article published on 6 January 2017

Meprinβ, a novel mediator of vascular remodelling underlying pulmonary hypertension

scientific article published on 31 January 2014

Neurotrophic tyrosine kinase receptor B/neurotrophin 4 signaling axis is perturbed in clinical and experimental pulmonary fibrosis.

scientific article

Osteopontin protects against lung injury caused by extracellular histones

scientific article published on 16 August 2018

PAR-2 inhibition reverses experimental pulmonary hypertension

scientific article

Patients with ARDS show improvement but not normalisation of alveolar surface activity with surfactant treatment: putative role of neutral lipids

scientific article

Pirfenidone exerts antifibrotic effects through inhibition of GLI transcription factors

scientific article published in February 2017

Plasminogen activator inhibitor-1 is an inhibitor of factor VII-activating protease in patients with acute respiratory distress syndrome

scientific article published on 31 May 2007

Positioning of nucleosomes containing γ-H2AX precedes active DNA demethylation and transcription initiation

scientific article published on 16 February 2021

Pro- and antifibrinolytic properties of human pulmonary microvascular versus artery endothelial cells: impact of endotoxin and tumor necrosis factor-alpha.

scientific article published in January 2004

Protease-activated receptors (PAR)-1 and -3 drive epithelial-mesenchymal transition of alveolar epithelial cells - potential role in lung fibrosis.

scientific article published on 6 June 2013

Protein Arginine Methyltransferases (PRMTs): promising targets for the treatment of pulmonary disorders.

scientific article published on 27 September 2012

Protein arginine methyltransferase 5 mediates enolase-1 cell surface trafficking in human lung adenocarcinoma cells.

scientific article published in March 2018

Raised protein levels and altered cellular expression of factor VII activating protease (FSAP) in the lungs of patients with acute respiratory distress syndrome (ARDS).

scientific article published on 4 May 2007

Recombinant production of a hybrid plasminogen activator composed of surfactant protein B and low-molecular-weight urokinase

scientific article published in December 2008

Reduced expression of arrestin beta 2 by graft monocytes during acute rejection of rat kidneys.

scientific article published on 3 December 2010

Role of coagulation and fibrinolysis in lung and renal fibrosis.

scientific article published on February 2008

Role of protease-activated receptor-2 in idiopathic pulmonary fibrosis

scientific article published on 11 March 2011

STIM1/ORAI1-mediated Ca2+ Influx Regulates Enolase-1 Exteriorization.

scientific article published on 24 March 2015

Safety and tolerability of inhaled heparin in idiopathic pulmonary fibrosis

scientific article

Shedding of low-density lipoprotein receptor–related protein-1 in acute respiratory distress syndrome

scientific article published in August 2011

Signaling at the Crossroads: Matrix-Derived Proteoglycan and Reactive Oxygen Species Signaling.

scientific article published on 16 May 2017

Small Leucine-Rich Proteoglycans in Renal Inflammation: Two Sides of the Coin

scientific article published in October 2017

Src tyrosine kinase is crucial for potassium channel function in human pulmonary arteries.

scientific article

Surfactant protein C mutations in sporadic forms of idiopathic interstitial pneumonias

scientific article published on 27 September 2006

TGF-β directs trafficking of the epithelial sodium channel ENaC which has implications for ion and fluid transport in acute lung injury

scientific article published on 09 December 2013

TGF-β1 induces tissue factor expression in human lung fibroblasts in a PI3K/JNK/Akt-dependent and AP-1-dependent manner

scientific article published on 05 July 2012

Targeting renal fibrosis: Mechanisms and drug delivery systems.

scientific article published on 26 December 2017

Testosterone Replacement Effectively Inhibits the Development of Experimental Autoimmune Orchitis in Rats: Evidence for a Direct Role of Testosterone on Regulatory T Cell Expansion ⬇️

scientific article published on March 25, 2011

The interaction of enolase-1 with caveolae-associated proteins regulates its subcellular localization.

scientific article published on June 2014

The low density lipoprotein receptor-related protein (LRP) 1 and its function in lung diseases

scientific article published on March 2016

Time-dependent changes in pulmonary surfactant function and composition in acute respiratory distress syndrome due to pneumonia or aspiration

scientific article

Transcriptome profiling reveals the complexity of pirfenidone effects in idiopathic pulmonary fibrosis

scientific article published on 22 November 2018

Transforming growth factor-β1 induces expression of human coagulation factor XII via Smad3 and JNK signaling pathways in human lung fibroblasts

scientific article

Transgenic mice expressing a surfactant protein B–urokinase fusion protein in the distal respiratory epithelium are protected against acute lung injury and postinflammatory fibrosis.

scientific article published on 22 March 2007

Yarsagumba is a Promising Therapeutic Option for Treatment of Pulmonary Hypertension due to the Potent Anti-Proliferative and Vasorelaxant Properties

scientific article published on 16 March 2020

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