List of works - Michael W. Traxlmayr

A conformation-specific ON-switch for controlling CAR T cells with an orally available drug

scientific article published on 17 June 2020

An engineered protein antagonist of K-Ras/B-Raf interaction

scientific article

Construction of a stability landscape of the CH3 domain of human IgG1 by combining directed evolution with high throughput sequencing

scientific article

Construction of pH-sensitive Her2-binding IgG1-Fc by directed evolution

scientific article

Creating stable stem regions for loop elongation in Fcabs - insights from combining yeast surface display, in silico loop reconstruction and molecular dynamics simulations.

scientific article

Cytosolic delivery of siRNA by ultra-high affinity dsRNA binding proteins.

scientific article published on 21 June 2017

Design Principles for SuCESsFul Biosensors: Specific Fluorophore/Analyte Binding and Minimization of Fluorophore/Scaffold Interactions

scientific article

Directed Evolution of Protein Thermal Stability Using Yeast Surface Display.

scientific article

Directed evolution of Her2/neu-binding IgG1-Fc for improved stability and resistance to aggregation by using yeast surface display ⬇️

scientific article published on December 23, 2012

Directed evolution of proteins for increased stability and expression using yeast display ⬇️

scientific article published on May 3, 2012

Directed evolution of stabilized IgG1-Fc scaffolds by application of strong heat shock to libraries displayed on yeast

scientific article

Driving CARs with alternative navigation tools - the potential of engineered binding scaffolds

scientific article published on 13 August 2020

Engineered IgG1-Fc--one fragment to bind them all

scientific article

Engineering AvidCARs for combinatorial antigen recognition and reversible control of CAR function

scientific article published on 20 August 2020

Fcab-HER2 Interaction: a Ménage à Trois. Lessons from X-Ray and Solution Studies

scientific article published on 18 May 2017

Immune suppression by gammadelta T-cells as a potential regulatory mechanism after cancer vaccination with IL-12 secreting dendritic cells

scientific article published in January 2010

Integrin binding human antibody constant domains--probing the C-terminal structural loops for grafting the RGD motif.

scientific article

Protein Engineering and Selection Using Yeast Surface Display.

scientific article published on January 2015

Stability assessment on a library scale: a rapid method for the evaluation of the commutability and insertion of residues in C-terminal loops of the CH3 domains of IgG1-Fc

scientific article

Strong Enrichment of Aromatic Residues in Binding Sites from a Charge-neutralized Hyperthermostable Sso7d Scaffold Library.

scientific article

Two-faced Fcab prevents polymerization with VEGF and reveals thermodynamics and the 2.15 Å crystal structure of the complex.

scientific article

List of works by Michael W. Traxlmayr

A conformation-specific ON-switch for controlling CAR T cells with an orally available drug

An engineered protein antagonist of K-Ras/B-Raf interaction

Construction of a stability landscape of the CH3 domain of human IgG1 by combining directed evolution with high throughput sequencing

Construction of pH-sensitive Her2-binding IgG1-Fc by directed evolution

Creating stable stem regions for loop elongation in Fcabs - insights from combining yeast surface display, in silico loop reconstruction and molecular dynamics simulations.

Cytosolic delivery of siRNA by ultra-high affinity dsRNA binding proteins.

Design Principles for SuCESsFul Biosensors: Specific Fluorophore/Analyte Binding and Minimization of Fluorophore/Scaffold Interactions

Directed Evolution of Protein Thermal Stability Using Yeast Surface Display.

Directed evolution of Her2/neu-binding IgG1-Fc for improved stability and resistance to aggregation by using yeast surface display ⬇️

Directed evolution of proteins for increased stability and expression using yeast display ⬇️

Directed evolution of stabilized IgG1-Fc scaffolds by application of strong heat shock to libraries displayed on yeast

Driving CARs with alternative navigation tools - the potential of engineered binding scaffolds

Engineered IgG1-Fc--one fragment to bind them all

Engineering AvidCARs for combinatorial antigen recognition and reversible control of CAR function

Fcab-HER2 Interaction: a Ménage à Trois. Lessons from X-Ray and Solution Studies

Immune suppression by gammadelta T-cells as a potential regulatory mechanism after cancer vaccination with IL-12 secreting dendritic cells

Integrin binding human antibody constant domains--probing the C-terminal structural loops for grafting the RGD motif.

Protein Engineering and Selection Using Yeast Surface Display.

Stability assessment on a library scale: a rapid method for the evaluation of the commutability and insertion of residues in C-terminal loops of the CH3 domains of IgG1-Fc

Strong Enrichment of Aromatic Residues in Binding Sites from a Charge-neutralized Hyperthermostable Sso7d Scaffold Library.

Two-faced Fcab prevents polymerization with VEGF and reveals thermodynamics and the 2.15 Å crystal structure of the complex.