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Authors whose works are in public domain in at least one jurisdiction

List of works by Marc G Achen

A Simple Bioassay for the Evaluation of Vascular Endothelial Growth Factors

scientific article published on 15 March 2016

A Simple and Rapid Method for Genetic Transformation of Lactic Streptococci by Electroporation.

scientific article published in March 1988

A Three-Dimensional Lymphatic Endothelial Cell Tube Formation Assay to Identify Novel Kinases Involved in Lymphatic Vessel Remodeling

scientific article

A phase Ib/II translational study of sunitinib with neoadjuvant radiotherapy in soft-tissue sarcoma

scientific article

A role for bone morphogenetic protein-4 in lymph node vascular remodeling and primary tumor growth

scientific article

A system for quantifying the patterning of the lymphatic vasculature

scientific article published on 01 December 2007

Adenoviral catheter-mediated intramyocardial gene transfer using the mature form of vascular endothelial growth factor-D induces transmural angiogenesis in porcine heart

scientific article published on 16 February 2004

Adenovirus encoding vascular endothelial growth factor-D induces tissue-specific vascular patterns in vivo.

scientific article published in June 2002

Angiogenic Responses of Vascular Endothelial Growth Factors in Periadventitial Tissue

article

Arap3 is dysregulated in a mouse model of hypotrichosis-lymphedema-telangiectasia and regulates lymphatic vascular development.

scientific article

Biosynthesis of vascular endothelial growth factor-D involves proteolytic processing which generates non-covalent homodimers

scientific article (publication date: 5 November 1999)

Ccbe1 regulates Vegfc-mediated induction of Vegfr3 signaling during embryonic lymphangiogenesis

scientific article published on 12 February 2014

Cerebral expression of transthyretin: evolution, ontogeny and function

scientific article published on January 1, 1992

Construction of plasmid vectors for the detection of streptococcal promoters

scientific article

Current strategies for modulating lymphangiogenesis signalling pathways in human disease.

scientific article

Deletion of vascular endothelial growth factor C (VEGF-C) and VEGF-D is not equivalent to VEGF receptor 3 deletion in mouse embryos

scientific article published on 2 June 2008

Differential Receptor Binding and Regulatory Mechanisms for the Lymphangiogenic Growth Factors Vascular Endothelial Growth Factor (VEGF)-C and -D.

scientific article

Distinct roles of vascular endothelial growth factor-D in lymphangiogenesis and metastasis

scientific article published on April 2007

Emerging Roles for VEGF-D in Human Disease

scientific article published on 4 January 2018

Exploring the role of endothelium in the tumour response to anti-angiogenic therapy.

scientific article

Expression of the HT7 gene in blood-brain barrier.

scientific article

Expression of vascular endothelial growth factor receptor-3 by lymphatic endothelial cells is associated with lymph node metastasis in prostate cancer

scientific article published on August 2004

Focus on lymphangiogenesis in tumor metastasis.

scientific article

From anti-angiogenesis to anti-lymphangiogenesis: emerging trends in cancer therapy.

scientific article published on January 2008

Genome-wide functional analysis reveals central signaling regulators of lymphatic endothelial cell migration and remodeling.

scientific article published on 3 October 2017

Growth factors regulating lymphatic vessels

scientific article published on 01 January 2000

Hypoxia-induced transcriptional activation and increased mRNA stability of vascular endothelial growth factor in C6 glioma cells

scientific article published in August 1995

Intestinal-specific activatable Myb initiates colon tumorigenesis in mice.

scientific article published on 24 August 2015

Isolation, characterization, cDNA cloning and gene expression of an avian transthyretin. Implications for the evolution of structure and function of transthyretin in vertebrates ⬇️

scientific article published on September 15, 1991

Localization of vascular endothelial growth factor-D in malignant melanoma suggests a role in tumour angiogenesis

scientific article published on 01 February 2001

Lymphangiogenesis and cancer metastasis

scientific article

Lymphangiogenesis and lymphatic vessel remodelling in cancer

scientific article published on March 2014

Lymphangiogenic growth factor responsiveness is modulated by postnatal lymphatic vessel maturation

scientific article published on August 2006

Lymphatic endothelium: an important interactive surface for malignant cells.

scientific article

Lymphatic vessel density in primary melanomas predicts sentinel lymph node status and risk of metastasis

scientific article published on 01 October 2012

Lymphatic vessels in cancer metastasis: bridging the gaps

scientific article

Lymphovascular and neural regulation of metastasis: shared tumour signalling pathways and novel therapeutic approaches

scientific article

Mapping of the gene for vascular endothelial growth factor-D in mouse and man to the X chromosome

scientific article published on 01 November 1997

Molecular control of lymphatic metastasis.

scientific article published on January 2008

Molecular pathways for lymphangiogenesis and their role in human disease.

scientific article published on January 2007

Molecular regulation of the VEGF family -- inducers of angiogenesis and lymphangiogenesis.

scientific article

Molecular targeting of lymphatics for therapy.

scientific article published on January 2004

Multiple forms of mouse vascular endothelial growth factor-D are generated by RNA splicing and proteolysis

scientific article

Pathogenesis of persistent lymphatic vessel hyperplasia in chronic airway inflammation.

scientific article

Placenta growth factor and vascular endothelial growth factor are co-expressed during early embryonic development

scientific article published in January 1997

Plasmin activates the lymphangiogenic growth factors VEGF-C and VEGF-D

scientific article

Preparation of human vascular endothelial growth factor-D for structural and preclinical therapeutic studies.

scientific article published on 10 January 2012

Proprotein convertases promote processing of VEGF-D, a critical step for binding the angiogenic receptor VEGFR-2

scientific article published on 22 January 2007

Regenerating lizard tails: a new model for investigating lymphangiogenesis

scientific article published on 02 January 2003

Remodeling of the lymphatic vasculature during mouse mammary gland morphogenesis is mediated via epithelial-derived lymphangiogenic stimuli

scientific article published on 11 October 2012

Sampling the Genomic Pool of Protein Tyrosine Kinase Genes Using the Polymerase Chain Reaction with Genomic DNA ⬇️

scientific article published on August 28, 1998

Signaling for lymphangiogenesis via VEGFR-3 is required for the early events of metastasis.

scientific article published on 17 April 2013

Systematic high-content genome-wide RNAi screens of endothelial cell migration and morphology

scientific article

Targeting lymphangiogenesis to prevent tumour metastasis

scientific article

Targeting tumor stroma

scientific article published on 01 September 2008

The Angiogenic and Lymphangiogenic Factor Vascular Endothelial Growth Factor-D Exhibits a Paracrine Mode of Action in Cancer

scientific article published on 01 June 2002

The Role of the Tumor Vasculature in the Host Immune Response: Implications for Therapeutic Strategies Targeting the Tumor Microenvironment

scientific article published on 20 December 2016

The VD1 neutralizing antibody to vascular endothelial growth factor-D: binding epitope and relationship to receptor binding

scientific article published on 18 February 2011

The connection between lymphangiogenic signalling and prostaglandin biology: a missing link in the metastatic pathway.

scientific article

The fibrinolysis inhibitor α2-antiplasmin restricts lymphatic remodelling and metastasis in a mouse model of cancer

scientific article published on 11 July 2017

The non-receptor tyrosine kinase Lyn is localised in the developing murine blood-brain barrier

scientific article published on 01 July 1995

The propeptides of VEGF-D determine heparin binding, receptor heterodimerization, and effects on tumor biology.

scientific article published on 12 February 2013

The proteolytic activation of angiogenic and lymphangiogenic growth factors in cancer--its potential relevance for therapeutics and diagnostics

scientific article published on 17 December 2013

The role of tumor lymphangiogenesis in metastatic spread.

scientific article

The specificity of receptor binding by vascular endothelial growth factor-d is different in mouse and man

scientific article (publication date: June 2001)

The vascular endothelial growth factor family: signalling for vascular development.

scientific article

Tissues in different anatomical sites can sculpt and vary the tumor microenvironment to affect responses to therapy

scientific article published on 19 September 2013

Tumor location and nature of lymphatic vessels are key determinants of cancer metastasis ⬇️

scientific article published on November 3, 2012

Tumor lymphangiogenesis and metastatic spread-new players begin to emerge.

scientific article

VEGF-C and VEGF-D expression in neuroendocrine cells and their receptor, VEGFR-3, in fenestrated blood vessels in human tissues

scientific article published on 01 October 2000

VEGF-D is an X-linked/AP-1 Regulated Putative Onco-angiogen in Human Glioblastoma Multiforme ⬇️

scientific article published on September 1, 2001

VEGF-D is the strongest angiogenic and lymphangiogenic effector among VEGFs delivered into skeletal muscle via adenoviruses

scientific article (publication date: 30 May 2003)

VEGF-D promotes pulmonary oedema in hyperoxic acute lung injury

scientific article published on 29 February 2016

VEGF-D promotes the metastatic spread of tumor cells via the lymphatics

scientific article (publication date: February 2001)

VEGFD regulates blood vascular development by modulating SOX18 activity.

scientific article published on 22 November 2013

Vascular endothelial growth factor D (VEGF-D) is a ligand for the tyrosine kinases VEGF receptor 2 (Flk1) and VEGF receptor 3 (Flt4)

scientific article

Vascular endothelial growth factor D is dispensable for development of the lymphatic system

scientific article

Vascular endothelial growth factor-D expression in human atherosclerotic lesions

scientific article published on 01 October 2003

Vascular endothelial growth factor-D over-expressing tumor cells induce differential effects on uterine vasculature in a mouse model of endometrial cancer

scientific article

Vascular endothelial growth factor-D: signaling mechanisms, biology, and clinical relevance ⬇️

scientific article published on July 20, 2012

Vascular endothelial growth factor-d modulates caliber and function of initial lymphatics in the dermis

scientific article published on 25 February 2013

Vascular remodeling in cancer.

scientific article published on 05 August 2013

Vegfd modulates both angiogenesis and lymphangiogenesis during zebrafish embryonic development

scientific article published on 13 January 2017

Viral Vascular Endothelial Growth Factors Vary Extensively in Amino Acid Sequence, Receptor-binding Specificities, and the Ability to Induce Vascular Permeability yet Are Uniformly Active Mitogens

scientific article published in Journal of Biological Chemistry

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