List of works by Ulf-Håkan Stenman

A Four-kallikrein Panel and β-Microseminoprotein in Predicting High-grade Prostate Cancer on Biopsy: An Independent Replication from the Finnish Section of the European Randomized Study of Screening for Prostate Cancer

scientific article published on 11 November 2017

A comprehensive nomenclature for serine proteases with homology to tissue kallikreins

scientific article

A high-density tissue microarray from patients with clinically localized prostate cancer reveals ERG and TATI exclusivity in tumor cells.

scientific article published on 5 March 2013

A nationwide survey of mortality in acromegaly

scientific article

Absence of TGF-β Receptor Activation by Highly Purified hCG Preparations.

scientific article

Activity and stability of human kallikrein-2-specific linear and cyclic peptide inhibitors

article

Advances in Prostate-Specific Antigen Testing

scientific article

Algorithms based on prostate-specific antigen (PSA), free PSA, digital rectal examination and prostate volume reduce false-positive PSA results in prostate cancer screening

scientific article published on August 2004

An Investigation of the Single and Combined Phthalate Metabolite Effects on Human Chorionic Gonadotropin Expression in Placental Cells

scientific article

An abnormal relation between basal prolactin levels and prolactin response to 12.5 microg TRH i.v. in drug-naïve patients with first-episode schizophrenia

scientific article published in June 2010

An immunocapture-LC-MS-based assay for serum SPINK1 allows simultaneous quantification and detection of SPINK1 variants

scientific article published on 9 January 2018

An optimized isolation of biotinylated cell surface proteins reveals novel players in cancer metastasis

scientific article

Antiangiogenic properties of prostate-specific antigen (PSA).

scientific article published on January 2009

Application of proteomic technology in identifying pancreatic secretory trypsin inhibitor variants in urine of patients with pancreatitis

scientific article published on 27 October 2005

Association of SPINK1 expression and TMPRSS2:ERG fusion with prognosis in endocrine-treated prostate cancer

scientific article published on 04 May 2010

Association of trypsin-2 with activation of gelatinase B and collagenase-2 in human bronchoalveolar lavage fluidin vivo

scientific article published on 01 September 2001

Association of tumor-associated trypsin inhibitor (TATI) expression with molecular markers, pathologic features and clinical outcomes of urothelial carcinoma of the urinary bladder

scientific article published on 08 July 2011

Binding of hepcidin to plasma proteins

scientific article published on 14 May 2012

Biochemistry and clinical role of trypsinogens and pancreatic secretory trypsin inhibitor

scientific article

Biomarker development, from bench to bedside

scientific article published on 19 August 2015

Candidate epitopes for measurement of hCG and related molecules: the second ISOBM TD-7 workshop.

scientific article published on 26 September 2013

Characterization of monoclonal antibodies against prostate specific antigen produced by genetic immunization

scientific article published in June 2004

Characterizing urinary hCGβcf patterns during pregnancy

scientific article published on 14 April 2016

Chlorpromazine and apigenin reduce adenovirus replication and decrease replication associated toxicity

scientific article published in January 2007

Circulating sex hormones in relation to anthropometric, sociodemographic and behavioural factors in an international dataset of 12,300 men.

scientific article published on 27 December 2017

Collagen degradation by tumor-associated trypsins.

scientific article published on 28 March 2013

Combination of serum hCG beta and p53 tissue expression defines distinct subgroups of serous ovarian carcinoma

scientific article published on 01 May 2008

Combining 33 genetic variants with prostate-specific antigen for prediction of prostate cancer: longitudinal study.

scientific article

Comparison of two growth hormone stimulation tests and their cut-off limits in healthy adults at an outpatient clinic

scientific article published on 6 July 2013

Complex formation between human prostate-specific antigen and protease inhibitors in mouse plasma

scientific article

Concentration of free hCGbeta subunit in serum as a prognostic marker for squamous-cell carcinoma of the oral cavity and oropharynx

scientific article published on 01 October 1999

Concentrations of vascular endothelial growth factor C and D in amniotic fluid and maternal plasma.

scientific article published in January 2009

Concomitant tumor expression of EGFR and TATI/SPINK1 associates with better prognosis in colorectal cancer

scientific article

Conformational and biochemical analysis of the cyclic peptides which modulate serine protease activity

scientific article

DNA damage recognition via activated ATM and p53 pathway in nonproliferating human prostate tissue

scientific article published on 26 October 2010

Design-corrected variation by centre in mortality reduction in the ERSPC randomised prostate cancer screening trial.

scientific article published on 9 August 2016

Desmosterol accumulation in users of amiodarone.

scientific article published on September 2017

Detection of complexes between prostate-specific antigen and protease inhibitors in plasma

scientific article published on 12 October 2010

Determination of aldosterone in serum by liquid chromatography-tandem mass spectrometry

scientific article published on 17 November 2007

Determination of human chorionic gonadotropin

scientific article published on 26 October 2013

Determination of steroid hormone concentrations

scientific article published on 01 July 2015

Determining the mechanisms of dietary turnip rapeseed oil on cholesterol metabolism in men with metabolic syndrome

scientific article published on 11 August 2017

Development of molecules stimulating the activity of KLK3 - an update.

scientific article

Diagnostic value of free prostate-specific antigen among men with a prostate-specific antigen level of <3.0 microg per liter

scientific article published on 5 November 2007

Differences in recognition of the 1st WHO international reference reagents for hCG-related isoforms by diagnostic immunoassays for human chorionic gonadotropin.

scientific article published on 18 June 2009

Effect of sex and assay method on serum concentrations of growth hormone in patients with acromegaly and in healthy controls

scientific article published on 26 January 2006

Effects of radiation therapy on tissue and serum concentrations of tumour associated trypsin inhibitor and their prognostic significance in rectal cancer patients

scientific article

Elimination of complement interference in immunoassay of hyperglycosylated human chorionic gonadotropin

scientific article published on 28 March 2011

Emerging Roles of SPINK1 in Cancer.

scientific article

Endostatin Inhibits Human Tongue Carcinoma Cell Invasion and Intravasation and Blocks the Activation of Matrix Metalloprotease-2, -9, and -13 ⬇️

scientific article published on April 10, 2003

Enhanced detection of cholangiocarcinoma with serum trypsinogen-2 in patients with severe bile duct strictures

scientific article

Epitope analysis and detection of human chorionic gonadotropin (hCG) variants by monoclonal antibodies and mass spectrometry.

scientific article

Epitope mapping of antibodies against prostate-specific antigen with use of peptide libraries.

scientific article published in December 2002

Erythropoietin is detectable in the ascitic fluid in patients with ovarian tumors

Establishment, value assignment, and characterization of new WHO reference reagents for six molecular forms of human chorionic gonadotropin

scientific article published on 28 October 2004

Estimating the probability of cancer with several tumor markers in patients with colorectal disease

scientific article

Estimation of prostate cancer risk on the basis of total and free prostate-specific antigen, prostate volume and digital rectal examination

scientific article published on June 2002

Evaluation of peptides as protease inhibitors and stimulators.

scientific article published in January 2014

Expression of human chorionic gonadotropin beta-subunit type I genes predicts adverse outcome in renal cell carcinoma

scientific article published on November 2006

Expression of human chorionic gonadotropin in testicular germ cell tumors.

scientific article

Expression of trypsinogen-1, trypsinogen-2, and tumor-associated trypsin inhibitor in ovarian cancer: prognostic study on tissue and serum.

scientific article

Expression of tumor-associated trypsinogens (TAT-1 and TAT-2) in prostate cancer

scientific article published in June 2005

False-negative results from point-of-care qualitative human chorionic gonadotropin (hCG) devices caused by excess hCGbeta core fragment vary with device lot number

scientific article published on 13 August 2009

False-negative results in point-of-care qualitative human chorionic gonadotropin (hCG) devices due to excess hCGbeta core fragment.

scientific article published on 24 April 2009

Family history and prostate cancer screening with prostate-specific antigen

scientific article

Fetal hypoxia is associated with elevated cord serum C-reactive protein levels in diabetic pregnancies

scientific article published on 12 January 2004

First Morning Voided Urinary Gonadotropin Measurements as an Alternative to the GnRH Test

scientific article published on 25 March 2016

First trimester hyperglycosylated human chorionic gonadotrophin in serum - a marker of early-onset preeclampsia.

scientific article published on 28 August 2013

First trimester serum placental growth factor and hyperglycosylated human chorionic gonadotropin are associated with pre-eclampsia: a case control study

scientific article

Free beta-subunit of human chorionic gonadotropin in serum is a diagnostically sensitive marker of seminomatous testicular cancer

scientific article published on 11 September 2008

Frontal electroencephalogram variables are associated with the outcome and stage of hepatic encephalopathy in acute liver failure.

scientific article published on 15 September 2014

Gender has to be taken into account in diagnosing adult growth hormone deficiency by the GHRH plus arginine test

scientific article

Glycodelin reduces breast cancer xenograft growth in vivo.

scientific article

High levels of circulating testosterone are not associated with increased prostate cancer risk: a pooled prospective study

scientific article

Human chorionic gonadotropin and its free β-subunit stimulate trophoblast invasion independent of LH/hCG receptor.

scientific article published on 17 May 2013

Human chorionic gonadotropin in cancer

scientific article published in July 2004

Hyperglycosylated human chorionic gonadotropin in serum of testicular cancer patients.

scientific article published on 23 April 2012

Hypothermia-treated cardiac arrest patients with good neurological outcome differ early in quantitative variables of EEG suppression and epileptiform activity

scientific article

Identification of IGFBP-3 fragments generated by KLK2 and prevention of fragmentation by KLK2-inhibiting peptides

scientific article published in April 2010

Identification of novel peptide inhibitors for human trypsins.

scientific article published in February 2010

Improving immunoassay performance by antibody engineering.

scientific article published in May 2005

Increased Activity of the Hypothalamic-Pituitary-Testicular Axis in Infancy Results in Increased Androgen Action in Premature Boys

scientific article published on 29 September 2010

Increased expression of tumor-associated trypsin inhibitor, TATI, in prostate cancer and in androgen-independent 22Rv1 cells

scientific article published on 5 February 2007

Increased serum levels of tumour-associated trypsin inhibitor independently predict a poor prognosis in colorectal cancer patients

scientific article

Independent prognostic value of preoperative serum markers CA 242, specific tissue polypeptide antigen and human chorionic gonadotrophin beta, but not of carcinoembryonic antigen or tissue polypeptide antigen in colorectal cancer

scientific article

Infectivity-enhanced adenoviruses deliver efficacy in clinical samples and orthotopic models of disseminated gastric cancer

scientific article published in May 2006

Interleukin-6 increases expression of serine protease inhibitor Kazal type 1 through STAT3 in colorectal adenocarcinoma.

scientific article published on 14 December 2015

Intracellular co-localization of trypsin-2 and matrix metalloprotease-9: possible proteolytic cascade of trypsin-2, MMP-9 and enterokinase in carcinoma

scientific article published on 12 November 2007

Is serum-soluble vascular endothelial growth factor receptor-1 of importance in unexplained infertility?

scientific article published on 01 January 2008

KLF6 IVS1 -27G>A Variant and the Risk of Prostate Cancer in Finland

scientific article published on 17 November 2006

Longitudinal biobanks-based study on the joint effects of infections, nutrition and hormones on risk of prostate cancer

scientific article published on 15 February 2016

Loss of PTEN is associated with aggressive behavior in ERG-positive prostate cancer

scientific article

Loss of human chorionic gonadotropin in urine during storage at -20°C.

scientific article published on 4 October 2011

Mass spectrometric detection of tyrosine sulfation in human pancreatic trypsinogens, but not in tumor-associated trypsinogen

scientific article published on 10 December 2007

Maternal serum angiopoietin-1 and -2 and tie-2 in early pregnancy ending in preeclampsia or intrauterine growth retardation

scientific article published on 29 October 2009

Maternal serum endostatin at gestational weeks 16-20 is elevated in subsequent pre-eclampsia but not in intrauterine growth retardation.

scientific article published in January 2009

Maternal serum-soluble vascular endothelial growth factor receptor-1 in early pregnancy ending in preeclampsia or intrauterine growth retardation

scientific article published on 01 November 2005

Mimetics of the disulfide bridge between the N- and C-terminal cysteines of the KLK3-stimulating peptide B-2.

scientific article published on 5 December 2009

Monitoring of seminoma patients with serum markers

scientific article published on 12 April 2013

Monoclonal antibodies, immunofluorometric assay, and detection of human semenogelin in male reproductive tract: no association with in vitro fertilizing capacity of sperm

scientific article published on 01 March 2002

Mre11 inhibition by oncolytic adenovirus associates with autophagy and underlies synergy with ionizing radiation

scientific article

Mutations N34S and P55S of the SPINK1 gene in patients with chronic pancreatitis or pancreatic cancer and in healthy subjects: a report from Finland

scientific article

National Academy of Clinical Biochemistry laboratory medicine practice guidelines for use of tumor markers in testicular, prostate, colorectal, breast, and ovarian cancers

scientific article

Novel peptide inhibitors of human kallikrein 2.

scientific article

Novel small molecule inhibitors for prostate-specific antigen

scientific article

Number of screens for overdetection as an indicator of absolute risk of overdiagnosis in prostate cancer screening

scientific article published on 11 January 2012

On the use of prostate-specific antigen for screening of prostate cancer in European Randomised Study for Screening of Prostate Cancer

scientific article published on 01 November 2010

Outcomes of Prostate Cancer Screening by 5α-Reductase Inhibitor Use.

scientific article published on 16 February 2017

Outcomes of Prostate-specific Antigen-based Prostate Cancer Screening Among Men Using Nonsteroidal Anti-inflammatory Drugs.

scientific article published on 24 March 2017

Overexpression of human chorionic gonadotropin beta genes 3, 5 and 8 in tumor tissue and urinary cells of bladder cancer patients.

scientific article published in December 2006

PSA forms complexes with α1-antichymotrypsin in prostate.

scientific article

Pancreatic secretory trypsin inhibitor from human amniotic fluid and fetal and neonatal urine: concentrations and physicochemical characterization

scientific article published on 01 April 1986

Peptides binding to prostate-specific antigen enhance its antiangiogenic activity

scientific article published on 16 March 2012

Pitfalls in hormone determinations

scientific article published on 27 August 2013

Pitfalls in hormone determinations

scientific article

Placental 11 beta-hydroxysteroid dehydrogenase-2 and fetal cortisol/cortisone shuttle in small preterm infants

scientific article

Placental 11beta-HSD2 activity, early postnatal clinical course, and adrenal function in extremely low birth weight infants

scientific article published in April 2006

Platelet serotonin 5-HT2A receptor binding in patients with carcinoid tumor

scientific article published in January 2004

Polymorphisms of Genes Involved in Glucose and Energy Metabolic Pathways and Prostate Cancer: Interplay with Metformin.

scientific article published on 26 March 2015

Postoperative CEA is a better prognostic marker than CA19-9, hCGβ or TATI after resection of colorectal liver metastases

scientific article published in January 2018

Preanalytical factors and reference intervals for serum hepcidin LC-MS/MS method

scientific article

Prediction of pre-eclampsia and its subtypes in high-risk cohort: hyperglycosylated human chorionic gonadotropin in multivariate models.

scientific article published on 3 July 2018

Preoperative hCGbeta and CA 72-4 are prognostic factors in gastric cancer

scientific article

Preoperative serum hCGbeta as a prognostic marker in primary fallopian tube carcinoma

scientific article published on 08 December 2005

Prognostic significance of tumor-associated trypsin inhibitor (TATI) and human chorionic gonadotropin-β (hCGβ) in patients with hepatocellular carcinoma

scientific article published on 29 July 2013

Prognostic value of serum markers for prostate cancer

scientific article

Prostate cancer and PSA among statin users in the Finnish prostate cancer screening trial.

scientific article published in October 2010

Prostate cancer mortality in the Finnish randomized screening trial

scientific article published on 11 March 2013

Prostate cancer risk and nonsteroidal antiinflammatory drug use in the Finnish prostate cancer screening trial

scientific article

Prostate specific antigen for early detection of prostate cancer: longitudinal study

scientific article published on 24 September 2009

Proteins of the human endometrium. Basic and clinical studies toward a blood test for endometrial function

scientific article published on 01 January 1988

Proteolytic activity of prostate-specific antigen (PSA) towards protein substrates and effect of peptides stimulating PSA activity

scientific article

Proximity ligation measurement of the complex between prostate specific antigen and alpha1-protease inhibitor

scientific article published on 30 July 2009

Pseudopeptides with a centrally positioned alkene-based disulphide bridge mimetic stimulate kallikrein-related peptidase 3 activity

scholarly article by Kristian Meinander et al published 2013 in MedChemComm

Pulmonary trypsin-2 in the development of bronchopulmonary dysplasia in preterm infants.

scientific article published in September 2003

Quality of life in treated patients with acromegaly

scientific article published on 18 July 2006

Reference intervals for and validation of recalibrated immunoassays for trypsinogen-1 and trypsinogen-2

scientific article published on 20 August 2012

Relative concentrations of hK2/PSA mRNA in benign and malignant prostatic tissue.

scientific article

Replacement of the Disulfide Bridge in a KLK3-Stimulating Peptide Using Orthogonally Protected Building Blocks.

scientific article published on 16 December 2013

Results of the three rounds of the Finnish Prostate Cancer Screening Trial--the incidence of advanced cancer is decreased by screening

scientific article published in October 2010

Role of the tumor-associated trypsin inhibitor SPINK1 in cancer development

scientific article published on 23 May 2011

Rye whole grain and bran intake compared with refined wheat decreases urinary C-peptide, plasma insulin, and prostate specific antigen in men with prostate cancer

scientific article published on 27 October 2010

SELDI-TOF MS versus prostate specific antigen analysis of prospective plasma samples in a nested case-control study of prostate cancer

scientific article

SPINK1: a new therapeutic target in cancer?

scientific article published on 30 August 2011

Screening and prostate cancer mortality: results of the European Randomised Study of Screening for Prostate Cancer (ERSPC) at 13 years of follow-up.

scientific article

Second round results of the Finnish population-based prostate cancer screening trial

scientific article

Sensitive protein detection via triple-binder proximity ligation assays.

scientific article

Separation of enzymatically active and inactive prostate-specific antigen (PSA) by peptide affinity chromatography

scientific article published in March 2004

Serum HCG beta and CA 72-4 are stronger prognostic factors than CEA, CA 19-9 and CA 242 in pancreatic cancer

scientific article

Serum HCG beta, CA 72-4 and CEA are independent prognostic factors in colorectal cancer

scientific article (publication date: 20 October 2002)

Serum MMP-8 and TIMP-1 predict prognosis in colorectal cancer.

scientific article published on 22 June 2018

Serum concentrations of human chorionic gonadotropin beta and its association with survival in patients with colorectal cancer

scientific article published on 01 January 2012

Serum estradiol, testosterone, and sex hormone-binding globulin as regulators of peak bone mass and bone turnover rate in young Finnish men.

scientific article

Serum hyperglycosylated human chorionic gonadotrophin at 14-17 weeks of gestation does not predict preeclampsia

Serum proprotein convertase subtilisin/kexin type 9 concentration is not increased by plant stanol ester consumption in normo- to moderately hypercholesterolaemic non-obese subjects. The BLOOD FLOW intervention study

scientific article published on 10 April 2015

Serum testosterone levels during early pregnancy in patients developing preeclampsia

scientific article published on 16 May 2011

Site-specific glycan analysis of human chorionic gonadotropin beta-subunit from malignancies and pregnancy by liquid chromatography--electrospray mass spectrometry

scientific article published on 31 July 2006

Smoking and sVEGFR-1: circulating maternal concentrations and placental expression.

scientific article

Specific immunoassay reveals increased serum trypsinogen 3 in acute pancreatitis

scientific article published on 15 September 2011

Stability of first trimester placental growth factor in serum and whole blood

scientific article published on 26 October 2011

Standardization of assays for human chorionic gonadotropin

scientific article published in May 2004

Standardization of hormone determinations

scientific article published on 25 October 2013

Systemic Inflammatory Response and Elevated Tumour Markers Predict Worse Survival in Resectable Pancreatic Ductal Adenocarcinoma

scientific article

TATI as a biomarker

scientific article published on 26 February 2014

Targeted gene-expression analysis by genome-controlled reverse transcription-PCR.

scientific article published on 21 September 2006

Test sensitivity of prostate-specific antigen in the Finnish randomised prostate cancer screening trial

scientific article published on October 2004

The Finnish prostate cancer screening trial: Analyses on the screening failures

scientific article published on 10 November 2014

The Number of Screening Cycles Needed to Reduce Prostate Cancer Mortality in the Finnish Section of the European Randomized Study of Prostate Cancer (ERSPC)

scholarly article by Tomi Pakarainen et al published 15 October 2018 in Clinical Cancer Research

The classification, functions and clinical use of different isoforms of HCG.

scientific article published on 28 July 2006

The discovery of compounds that stimulate the activity of kallikrein-related peptidase 3 (KLK3).

scientific article published on 27 September 2011

The impact of interscreening interval and age on prostate cancer screening with prostate-specific antigen

scientific article published on 14 January 2012

The proportion of free PSA and upgrading of biopsy Gleason score after radical prostatectomy

scientific article published on 17 March 2010

The role of SPINK1 in ETS rearrangement-negative prostate cancers

scientific article

The role of glycodelin in cell differentiation and tumor growth.

scientific article published on January 2009

Tissue AP-2gamma and Oct-3/4, and serum CA 125 as diagnostic and prognostic markers of malignant ovarian germ cell tumors

scientific article

Treatment of prostate cancer with Ad5/3Delta24hCG allows non-invasive detection of the magnitude and persistence of virus replication in vivo

scientific article published in February 2007

Trypsin-2 degrades human type II collagen and is expressed and activated in mesenchymally transformed rheumatoid arthritis synovitis tissue

scientific article

Trypsin-2 enhances carcinoma invasion by processing tight junctions and activating ProMT1-MMP.

scientific article

Tumor characteristics in a population-based prostate cancer screening trial with prostate-specific antigen.

scientific article published in July 2003

Tumor-Associated Trypsinogen-2 (Trypsinogen-2) Activates Procollagenases (MMP-1, -8, -13) and Stromelysin-1 (MMP-3) and Degrades Type I Collagen ⬇️

scientific article published on May 13, 2003

Tumor-associated trypsin inhibitor.

scientific article

Tumour-associated trypsin inhibitor TATI is a prognostic marker in colorectal cancer

scientific article published on 12 April 2012

Up-regulation of trypsin and mesenchymal MMP-8 during development of hyperoxic lung injury in the rat

scientific journal article

Urinary levels of tumor-associated trypsin inhibitor (TATI) in the detection of transitional cell carcinoma of the urinary bladder

scientific article published in September 2005

Urinary matrix metalloproteinase -8, -9, -14 and their regulators (TRY-1, TRY-2, TATI) in patients with diabetic nephropathy

scientific article published on January 2008

Use of non-steroidal anti-inflammatory drugs and prostate cancer survival in the Finnish prostate cancer screening trial

scientific article published on 12 June 2015

Validating serum markers for monitoring of cancer

scientific article published on 31 October 2012

Validation and comparison of tumor-associated trypsin inhibitor (TATI) immunoassays

scientific article published on 06 April 2012

Virtual Screening of Small Drug-Like Compounds Stimulating the Enzymatic Activity of Kallikrein-Related Peptidase 3 (KLK3).

scientific article

Vitamin D status as a determinant of peak bone mass in young Finnish men.

scientific article

What explains the differences between centres in the European screening trial? A simulation study.

scientific article published on 24 November 2016

Why do men opt out of prostate-cancer screening? Attitudes and perception among participants and non-participants of a screening trial

scientific article

Will emerging prostate cancer markers redeem themselves?

scientific article published on 22 June 2010

Words of wisdom. Re: Periprostatic adipose tissue as a modulator of prostate cancer aggressiveness

scientific article published on 01 March 2010

Words of wisdom. Re: Therapeutic targeting of SPINK1-positive prostate cancer

scientific article published on 01 October 2012

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