List of works - Nigel J Walker

A critical comparison of murine pathology and epidemiological data of TCDD, PCB126, and PeCDF

scientific article

A new approach to synergize academic and guideline-compliant research: the CLARITY-BPA research program.

scientific article published on 05 June 2013

Absolute estimation of initial concentrations of amplicon in a real-time RT-PCR process

scientific article

Aloe vera non-decolorized whole leaf extract-induced large intestinal tumors in F344 rats share similar molecular pathways with human sporadic colorectal tumors.

scientific article published on 21 September 2011

Cerium dioxide nanoparticles do not modulate the lipopolysaccharide-induced inflammatory response in human monocytes ⬇️

scientific article published on March 13, 2012

Characterization of bronchiolar metaplasia of the alveolar epithelium in female Sprague-Dawley rats exposed to 3,3',4,4',5-pentachlorobiphenyl (PCB126).

scientific article

Characterization of the Dose–Response of CYP1B1, CYP1A1, and CYP1A2 in the Liver of Female Sprague–Dawley Rats Following Chronic Exposure to 2,3,7,8-Tetrachlorodibenzo-p-dioxin

scientific article published in February 1999

Classification of proliferative hepatocellular lesions in harlan sprague-dawley rats chronically exposed to dioxin-like compounds.

scientific article

Development of a refined database of mammalian relative potency estimates for dioxin-like compounds.

scientific article

Differences in kinetics of induction and reversibility of TCDD-induced changes in cell proliferation and CYP1A1 expression in female Sprague-Dawley rat liver.

scientific article published in August 1998

Dioxin (2,3,7,8-tetrachlorodibenzo-p-dioxin) enhances triggered afterdepolarizations in rat ventricular myocytes

scientific article

Dose-dependent localization of TCDD in isolated centrilobular and periportal hepatocytes

scientific article

Effects of TCDD upon IkappaB and IKK subunits localized in microsomes by proteomics

scientific journal article

Endotoxin (Lipopolysaccharide)-Induced Nitric Oxide Production in 2,3,7,8-Tetrachlorodibenzo-p-dioxin-Treated Fischer Rats: Detection of Nitrosyl Hemoproteins by EPR Spectroscopy

scientific article published in October 2000

Exocrine pancreatic pathology in female Harlan Sprague-Dawley rats after chronic treatment with 2,3,7,8-tetrachlorodibenzo-p-dioxin and dioxin-like compounds

scientific article

Follicular epithelial cell hypertrophy induced by chronic oral administration of 2,3,7,8-tetrachlorodibenzo-p-dioxin in female Harlan Sprague-Dawley rats.

scientific article

Gene expression alterations in immune system pathways in the thymus after exposure to immunosuppressive chemicals.

scientific article

Hepatocarcinogenesis in Female Sprague-Dawley Rats following Discontinuous Treatment with 2,3,7,8-Tetrachlorodibenzo-p-dioxin

scientific article published in April 2000

Incidences of selected lesions in control female Harlan Sprague-Dawley rats from two-year studies performed by the National Toxicology Program.

scientific article

Induction and localization of cytochrome P450 1B1 (CYP1B1) protein in the livers of TCDD-treated rats: detection using polyclonal antibodies raised to histidine-tagged fusion proteins produced and purified from bacteria

scientific article published in March 1998

Isolation and characterization of a novel gene induced by 2,3,7,8-tetrachlorodibenzo-p-dioxin in rat liver.

scientific article

Metabolism of benzo[a]pyrene and benzo[a]pyrene-7,8-diol by human cytochrome P450 1B1

scientific journal article

Migration of intradermally injected quantum dots to sentinel organs in mice

scientific article

Mixtures research at NIEHS: an evolving program.

scientific article

ONE Nano: NIEHS's strategic initiative on the health and safety effects of engineered nanomaterials

scientific article published on 12 February 2013

Olfactory epithelial metaplasia and hyperplasia in female Harlan Sprague-Dawley rats following chronic treatment with polychlorinated biphenyls.

scientific article

Physiological modeling of a proposed mechanism of enzyme induction by TCDD.

scientific article published in May 2001

Prevalence and sociodemographic correlates of antinuclear antibodies in the United States

scientific article published in July 2012

Pulmonary lesions in female Harlan Sprague-Dawley rats following two-year oral treatment with dioxin-like compounds

scientific article published on December 2007

Quantitative determination of skin penetration of PEG-coated CdSe quantum dots in dermabraded but not intact SKH-1 hairless mouse skin

scientific article

Real-time and quantitative PCR: applications to mechanism-based toxicology.

scientific article

Regulation of 2,3,7,8-tetrachlorodibenzo-p-dioxin-induced tumor promotion by 17 beta-estradiol in female Sprague--Dawley rats.

scientific article

Repeated dose toxicity and relative potency of 1,2,3,4,6,7-hexachloronaphthalene (PCN 66) 1,2,3,5,6,7-hexachloronaphthalene (PCN 67) compared to 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) for induction of CYP1A1, CYP1A2 and thymic atrophy in female H

scientific article published on 15 November 2012

Research strategies for safety evaluation of nanomaterials, part II: toxicological and safety evaluation of nanomaterials, current challenges and data needs

scientific article published on 24 August 2005

Safe handling of nanotechnology

scientific article (publication date: 16 November 2006)

Subchronic exposure to TCDD, PeCDF, PCB126, and PCB153: effect on hepatic gene expression

scientific article

Tech.Sight. A technique whose time has come.

scientific article

The 2005 World Health Organization reevaluation of human and Mammalian toxic equivalency factors for dioxins and dioxin-like compounds

scientific article

The putative tumor suppressor Tsc-22 is downregulated early in chemically induced hepatocarcinogenesis and may be a suppressor of Gadd45b.

scientific article published on 28 May 2007

The safety and regulation of natural products used as foods and food ingredients.

scientific article

Toxicity of chronic exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin in diethylnitrosamine-initiated ovariectomized rats implanted with subcutaneous 17 beta-estradiol pellets.

scientific article published in April 2000

Unraveling the Complexities of the Mechanism of Action of Dioxins

scientific article published on 8 November 2006

List of works by Nigel J Walker

A critical comparison of murine pathology and epidemiological data of TCDD, PCB126, and PeCDF

A new approach to synergize academic and guideline-compliant research: the CLARITY-BPA research program.

Absolute estimation of initial concentrations of amplicon in a real-time RT-PCR process

Aloe vera non-decolorized whole leaf extract-induced large intestinal tumors in F344 rats share similar molecular pathways with human sporadic colorectal tumors.

Cerium dioxide nanoparticles do not modulate the lipopolysaccharide-induced inflammatory response in human monocytes ⬇️

Characterization of bronchiolar metaplasia of the alveolar epithelium in female Sprague-Dawley rats exposed to 3,3',4,4',5-pentachlorobiphenyl (PCB126).

Characterization of the Dose–Response of CYP1B1, CYP1A1, and CYP1A2 in the Liver of Female Sprague–Dawley Rats Following Chronic Exposure to 2,3,7,8-Tetrachlorodibenzo-p-dioxin

Classification of proliferative hepatocellular lesions in harlan sprague-dawley rats chronically exposed to dioxin-like compounds.

Development of a refined database of mammalian relative potency estimates for dioxin-like compounds.

Differences in kinetics of induction and reversibility of TCDD-induced changes in cell proliferation and CYP1A1 expression in female Sprague-Dawley rat liver.

Dioxin (2,3,7,8-tetrachlorodibenzo-p-dioxin) enhances triggered afterdepolarizations in rat ventricular myocytes

Dose-dependent localization of TCDD in isolated centrilobular and periportal hepatocytes

Effects of TCDD upon IkappaB and IKK subunits localized in microsomes by proteomics

Endotoxin (Lipopolysaccharide)-Induced Nitric Oxide Production in 2,3,7,8-Tetrachlorodibenzo-p-dioxin-Treated Fischer Rats: Detection of Nitrosyl Hemoproteins by EPR Spectroscopy

Exocrine pancreatic pathology in female Harlan Sprague-Dawley rats after chronic treatment with 2,3,7,8-tetrachlorodibenzo-p-dioxin and dioxin-like compounds

Follicular epithelial cell hypertrophy induced by chronic oral administration of 2,3,7,8-tetrachlorodibenzo-p-dioxin in female Harlan Sprague-Dawley rats.

Gene expression alterations in immune system pathways in the thymus after exposure to immunosuppressive chemicals.

Hepatocarcinogenesis in Female Sprague-Dawley Rats following Discontinuous Treatment with 2,3,7,8-Tetrachlorodibenzo-p-dioxin

Incidences of selected lesions in control female Harlan Sprague-Dawley rats from two-year studies performed by the National Toxicology Program.

Induction and localization of cytochrome P450 1B1 (CYP1B1) protein in the livers of TCDD-treated rats: detection using polyclonal antibodies raised to histidine-tagged fusion proteins produced and purified from bacteria

Isolation and characterization of a novel gene induced by 2,3,7,8-tetrachlorodibenzo-p-dioxin in rat liver.

Metabolism of benzo[a]pyrene and benzo[a]pyrene-7,8-diol by human cytochrome P450 1B1

Migration of intradermally injected quantum dots to sentinel organs in mice

Mixtures research at NIEHS: an evolving program.

ONE Nano: NIEHS's strategic initiative on the health and safety effects of engineered nanomaterials

Olfactory epithelial metaplasia and hyperplasia in female Harlan Sprague-Dawley rats following chronic treatment with polychlorinated biphenyls.

Physiological modeling of a proposed mechanism of enzyme induction by TCDD.

Prevalence and sociodemographic correlates of antinuclear antibodies in the United States

Pulmonary lesions in female Harlan Sprague-Dawley rats following two-year oral treatment with dioxin-like compounds

Quantitative determination of skin penetration of PEG-coated CdSe quantum dots in dermabraded but not intact SKH-1 hairless mouse skin

Real-time and quantitative PCR: applications to mechanism-based toxicology.

Regulation of 2,3,7,8-tetrachlorodibenzo-p-dioxin-induced tumor promotion by 17 beta-estradiol in female Sprague--Dawley rats.

Repeated dose toxicity and relative potency of 1,2,3,4,6,7-hexachloronaphthalene (PCN 66) 1,2,3,5,6,7-hexachloronaphthalene (PCN 67) compared to 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) for induction of CYP1A1, CYP1A2 and thymic atrophy in female H

Research strategies for safety evaluation of nanomaterials, part II: toxicological and safety evaluation of nanomaterials, current challenges and data needs

Safe handling of nanotechnology

Subchronic exposure to TCDD, PeCDF, PCB126, and PCB153: effect on hepatic gene expression

Tech.Sight. A technique whose time has come.

The 2005 World Health Organization reevaluation of human and Mammalian toxic equivalency factors for dioxins and dioxin-like compounds

The putative tumor suppressor Tsc-22 is downregulated early in chemically induced hepatocarcinogenesis and may be a suppressor of Gadd45b.

The safety and regulation of natural products used as foods and food ingredients.

Toxicity of chronic exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin in diethylnitrosamine-initiated ovariectomized rats implanted with subcutaneous 17 beta-estradiol pellets.

Unraveling the Complexities of the Mechanism of Action of Dioxins