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List of works by Paul La Rosée

A case of Brooke-Spiegler syndrome with a novel mutation in the CYLD gene in a patient with aggressive non-Hodgkin's lymphoma.

scientific article published on 11 December 2015

A consensus review on malignancy-associated hemophagocytic lymphohistiocytosis in adults.

scientific article

Activity of the Bcr-Abl kinase inhibitor PD180970 against clinically relevant Bcr-Abl isoforms that cause resistance to imatinib mesylate (Gleevec, STI571).

scientific article published on December 2002

Alleviating the storm: ruxolitinib in HLH.

scientific article published in March 2016

Antileukemic activity of lysophosphatidic acid acyltransferase-beta inhibitor CT32228 in chronic myelogenous leukemia sensitive and resistant to imatinib

scientific article published on November 2006

BCR-ABL mutations in chronic myeloid leukemia

scientific article published on October 2011

Biomarker candidates for the detection of an infectious etiology of febrile neutropenia

scientific article published on 15 August 2015

Cause and management of therapy resistance

scientific article published on September 2009

Causes of resistance and treatment choices of second- and third-line treatment in chronic myelogenous leukemia patients

scientific article published on 27 March 2015

Choosing the best treatment strategy for chronic myeloid leukemia patients resistant to imatinib: weighing the efficacy and safety of individual drugs with BCR-ABL mutations and patient history.

scientific article published on October 2009

Chronic persistent parvovirus B19 bone marrow infection resulting in transfusion-dependent pure red cell aplasia in multiple myeloma after allogeneic haematopoietic stem cell transplantation and severe graft versus host disease

scientific article published on 16 June 2016

Complete remission after treatment with single-agent ofatumumab in a patient with high-risk leukemic mantle-cell lymphoma

scientific article

Consensus recommendations for the diagnosis and management of hemophagocytic lymphohistiocytosis associated with malignancies

scientific article published on August 2015

Desensitization of the pulmonary adenylyl cyclase system

scientific article published on 01 September 1999

Detection and quantification of residual disease in chronic myelogenous leukemia.

scientific article

Differential regulation of cardiac protein kinase C isozyme expression after aortic banding in rat.

scientific article published in October 2002

Drug-induced lymphadenopathy with eosinophilia and renal failure mimicking lymphoma disease: dramatic onset of DRESS syndrome associated with antibiotic treatment

Dynamics of BCR-ABL mutated clones prior to hematologic or cytogenetic resistance to imatinib

scientific article published on 26 January 2008

Effects of MLN518, a dual FLT3 and KIT inhibitor, on normal and malignant hematopoiesis

scientific article published on 8 July 2004

Efficacy and feasibility of cyclophosphamide combined with intermediate- dose or high-dose cytarabine for relapsed and refractory acute myeloid leukemia (AML).

scientific article published on 12 April 2014

Enhanced ABL-inhibitor-induced MAPK-activation in T315I-BCR-ABL-expressing cells: a potential mechanism of altered leukemogenicity

scientific article

Enhanced Bcr-Abl-specific antileukemic activity of arsenic trioxide (Trisenox) through glutathione-depletion in imatinib-resistant cells

scientific article published on June 2007

Epidemiology of invasive aspergillosis and azole resistance in patients with acute leukaemia: the SEPIA Study.

scientific article

First prospective clinical trial in adult HLH.

scientific article published on November 2015

Frequent polymorphism in BCR exon b2 identified in BCR-ABL positive and negative individuals using fluorescent hybridization probes

article

Fulminant Epstein-Barr virus-associated hemophagocytic lymphohistiocytosis

scientific article published on 30 May 2012

Fulminant gastrointestinal bleeding caused by EBV-triggered hemophagocytic lymphohistiocytosis: report of a case.

scientific article published on 9 April 2014

Hemophagocytic lymphohistiocytosis in adults

scientific article published on 10 August 2016

Imatinib and beyond--targeting activated tyrosine kinases in myeloproliferative disorders.

scientific article published on 20 January 2012

Impact of BCR-ABL mutations on patients with chronic myeloid leukemia.

scientific article published on 15 January 2011

Improved tolerability by a modified intermittent treatment schedule of dasatinib for patients with chronic myeloid leukemia resistant or intolerant to imatinib

article published in 2013

In vitro efficacy of combined treatment depends on the underlying mechanism of resistance in imatinib-resistant Bcr-Abl-positive cell lines

scientific article published on 21 August 2003

In vitro studies of the combination of imatinib mesylate (Gleevec) and arsenic trioxide (Trisenox) in chronic myelogenous leukemia

scientific article published on July 2002

Insights from pre-clinical studies for new combination treatment regimens with the Bcr-Abl kinase inhibitor imatinib mesylate (Gleevec/Glivec) in chronic myelogenous leukemia: a translational perspective.

scientific article

LASP1 is a novel BCR-ABL substrate and a phosphorylation-dependent binding partner of CRKL in chronic myeloid leukemia

scientific article published in July 2014

Lack of clinical efficacy of imatinib in metastatic melanoma

scientific article published on April 2005

Leriche’s syndrome and Löffler endocarditis in a 30-year-old patient presenting with hypereosinophilic syndrome

Modelling cost effectiveness of horse antithymocyte globulin for treating severe aplastic anaemia in Germany.

scientific article published on 13 February 2013

Molecular pathogenesis of tyrosine kinase resistance in chronic myeloid leukemia

scientific article published on March 2010

No correlation between the proliferative status of Bcr-Abl positive cell lines and the proapoptotic activity of imatinib mesylate (Gleevec/Glivec).

scientific article published in January 2003

Omacetaxine mepesuccinate prevents cytokine-dependent resistance to nilotinib in vitro: potential role of the common β-subunit c of cytokine receptors.

scientific article published on 13 January 2012

Optimizing therapy for patients with chronic myelogenous leukemia in chronic phase

scientific article published on March 2010

Ornithine transcarbamylase (OTC) deficiency based on a hemizygous p.R277W mutation causing life-threatening hyperammonemic crisis during treatment for Hodgkin’s lymphoma

Paradoxical MAPK-activation in response to treatment with tyrosine kinase inhibitors in CML: flow cytometry loses track

scientific article

Paraneoplastic inflammation in myelodysplastic syndrome or bone marrow failure: case series with focus on 5-azacytidine and literature review

scientific article published on 09 April 2014

Phospho-CRKL monitoring for the assessment of BCR-ABL activity in imatinib-resistant chronic myeloid leukemia or Ph+ acute lymphoblastic leukemia patients treated with nilotinib

scientific article published on 26 March 2008

Rapid treatment of leukostasis in leukemic mantle cell lymphoma using therapeutic leukapheresis: a case report.

scientific article

Recommendations for the management of hemophagocytic lymphohistiocytosis in adults

scientific article published on 16 April 2019

Regulation of protein kinase C isozymes in volume overload cardiac hypertrophy

scientific article published on 01 July 2004

Rescue of Cytokine Storm Due to HLH by Hemoadsorption in a CTLA4-Deficient Patient

scientific article

Resistance to imatinib in chronic myelogenous leukemia: mechanisms and clinical implications

scientific article published in April 2008

Resistance to imatinib: mutations and beyond.

scientific article published on October 2010

Sensitivity of oncogenic KIT mutants to the kinase inhibitors MLN518 and PD180970.

scientific article published on 10 August 2004

Several Bcr-Abl kinase domain mutants associated with imatinib mesylate resistance remain sensitive to imatinib

scientific article published on 6 February 2003

Standardization of preanalytical factors for minimal residual disease analysis in chronic myelogenous leukemia

scientific article published on January 2004

Successful treatment of neutropenic MRSA bacteremia with septic superior vena cava thrombus and cerebral embolism using high-dose daptomycin

scientific article

Systemic mastocytosis simulating osseous metastatic disease

scientific article published on 01 January 2007

Tailored management of chronic myeloid leukemia ⬇️

scientific article published on February 1, 2013

The Janus kinase 1/2 inhibitor ruxolitinib in COVID-19 with severe systemic hyperinflammation

scientific article published on 09 June 2020

The soluble transferrin receptor reflects tumor load in chronic lymphocytic leukemia

scientific article published on 01 January 2007

Treatment of hemophagocytic lymphohistiocytosis in adults

scientific article published in December 2015

Tyrosinekinase inhibition facilitates cooperation of transcription factor SALL4 and ABC transporter A3 towards intrinsic CML cell drug resistance.

scientific article published on 21 February 2013

Very severe thrombotic thrombocytopenic purpura (TTP) after H1N1 vaccination

scientific article

[Chronic myelogenous leukemia].

scientific article published in April 2015

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