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List of works by William Lehman

3-D image reconstruction of reconstituted smooth muscle thin filaments containing calponin: visualization of interactions between F-actin and calponin.

scientific article published on October 1997

35 kDa proteins are not components of vertebrate smooth muscle thin filaments

article

A comparison of muscle thin filament models obtained from electron microscopy reconstructions and low-angle X-ray fibre diagrams from non-overlap muscle

scientific article

A new twist on tropomyosin binding to actin filaments: perspectives on thin filament function, assembly and biomechanics

scientific article published on 15 February 2019

ADP binding to relaxed scallop myofibrils

scientific article published in Nature

Acetylation regulates tropomyosin function in the fission yeast Schizosaccharomyces pombe

scientific article published in May 2007

Altering the stability of the Cdc8 overlap region modulates the ability of this tropomyosin to bind co-operatively to actin and regulate myosin

scientific article published in September 2011

An actin subdomain 2 mutation that impairs thin filament regulation by troponin and tropomyosin.

scientific article published in July 2000

An atomic model for actin binding by the CH domains and spectrin-repeat modules of utrophin and dystrophin

scientific journal article

An atomic model of fimbrin binding to F-actin and its implications for filament crosslinking and regulation

scientific article published on September 1, 1998

An atomic model of the thin filament in the relaxed and Ca2+-activated states.

scientific article published on 13 January 2006

An open or closed case for the conformation of calponin homology domains on F-actin?

scientific article

Ca(2+)-induced tropomyosin movement in Limulus thin filaments revealed by three-dimensional reconstruction.

scientific article published on March 1994

Calcium-dependent myosin from insect flight muscles.

scientific article published on May 1974

Caldesmon and the structure of smooth muscle thin filaments: Immunolocalization of caldesmon on thin filaments

article

Caldesmon and the structure of smooth muscle thin filaments: electron microscopy of isolated thin filaments

article

Caldesmon and the structure of vertebrate smooth muscle thin filaments. A minireview.

scientific article published on January 1990

Caldesmon association with smooth muscle thin filaments isolated in the presence and absence of calcium

article

Cortactin binding to F-actin revealed by electron microscopy and 3D reconstruction

scientific article published on 04 May 2006

Curvature variation along the tropomyosin molecule.

scientific article

Diversity in smooth muscle thin filament composition

article

Drosophila muscle regulation characterized by electron microscopy and three-dimensional reconstruction of thin filament mutants.

scientific article

Effects of a cardiomyopathy-causing troponin t mutation on thin filament function and structure.

scientific article

Effects of basic calponin on the flexural mechanics and stability of F‐actin ⬇️

scientific article published on December 7, 2011

Electron microscopy and 3D reconstruction of F-actin decorated with cardiac myosin-binding protein C (cMyBP-C).

scientific article published on 13 May 2011

Electron microscopy and 3D reconstruction reveals filamin Ig domain binding to F-actin

scientific article

Electron microscopy and persistence length analysis of semi-rigid smooth muscle tropomyosin strands.

scientific article

FlnA binding to PACSIN2 F-BAR domain regulates membrane tubulation in megakaryocytes and platelets

scientific article published on 2 April 2015

Gestalt-binding of tropomyosin to actin filaments.

scientific article published on 31 December 2008

Mini-thin filaments regulated by troponin-tropomyosin

scientific article

Modes of caldesmon binding to actin: sites of caldesmon contact and modulation of interactions by phosphorylation.

scientific article published on 27 September 2004

Modulation of actin mechanics by caldesmon and tropomyosin.

scientific article

Myosin light chain kinase binding to a unique site on F-actin revealed by three-dimensional image reconstruction.

scientific article

Phylogenetic diversity of the proteins regulating muscular contraction

scientific article

Phylogenetic diversity of troponin subunit-C amino acid composition

article

Regulation in molluscan muscles

article

Regulation of muscular contraction. Distribution of actin control and myosin control in the animal kingdom ⬇️

scientific article published on July 1, 1975

Reversal of caldesmon function by anti-caldesmon antibodies confirms its role in the calcium regulation of vascular smooth muscle thin filaments

scientific article published on 01 August 1988

Single particle analysis of relaxed and activated muscle thin filaments.

scientific article published on 11 January 2005

Spontaneous transitions of actin-bound tropomyosin toward blocked and closed states

scientific article published on 15 November 2018

Steric-blocking by Tropomyosin Visualized in Relaxed Vertebrate Muscle Thin Filaments

article

Steric-model for activation of muscle thin filaments 1 1 Edited by P.E. Wright

article

Structural Analysis of Smooth Muscle Tropomyosin   and   Isoforms

scientific article

Structural basis for myopathic defects engendered by alterations in the myosin rod

scientific article published on 20 October 2011

Structural basis for the regulation of muscle contraction by troponin and tropomyosin

scientific article published on 3 May 2008

Structure and dynamics of the actin-based smooth muscle contractile and cytoskeletal apparatus ⬇️

scientific article published on February 7, 2012

The C terminus of cardiac troponin I stabilizes the Ca2+-activated state of tropomyosin on actin filaments

scientific article

The caldesmon content of vertebrate smooth muscle.

scientific article

The characterization of invertebrate troponin C

article

The distribution of troponin-like proteins on thin filaments of the bay scallop,Aequipecten irradians

article

The effect of calcium on the aggregation of chicken gizzard thin filaments

article

The flexibility of two tropomyosin mutants, D175N and E180G, that cause hypertrophic cardiomyopathy

scientific article

The ionic requirements for regulation by molluscan thin filaments

article

The location and periodicity of a troponin-T-like protein in the myofibril of the horseshoe crab Limulus polyphemus

article

The mechanism of thin filament regulation: Models in conflict?

scientific article published on 30 September 2019

The recruitment of acetylated and unacetylated tropomyosin to distinct actin polymers permits the discrete regulation of specific myosins in fission yeast.

scientific article

The relationship between curvature, flexibility and persistence length in the tropomyosin coiled-coil

scientific article

The shape and flexibility of tropomyosin coiled coils: implications for actin filament assembly and regulation.

scientific article

The stoichiometry of the components of arthropod thin filaments.

scientific article published in May 1976

The structural elements responsible for contraction in the ciliate Spirostomum

scientific article

The structure of the vertebrate striated muscle thin filament: a tribute to the contributions of Jean Hanson.

scientific article

The troponin tail domain promotes a conformational state of the thin filament that suppresses myosin activity.

scientific article published on 14 May 2002

The ultrastructural basis of actin filament regulation.

scientific article

Thick-filament-linked calcium regulation in vertebrate striated muscle ⬇️

scientific article published on July 6, 1978

Thin-filament-linked regulation in molluscan muscles

article

Three-dimensional image reconstruction of reconstituted smooth muscle thin filaments: effects of caldesmon

scientific article

Three-dimensional reconstruction of thin filaments containing mutant tropomyosin

scientific article

Tropomyosin and actin isoforms modulate the localization of tropomyosin strands on actin filaments.

scientific article published on September 2000

Tropomyosin position on F-actin revealed by EM reconstruction and computational chemistry.

scientific article

Tropomyosin positions in regulated thin filaments revealed by cryoelectron microscopy

scientific article

Tropomyosin variants describe distinct functional subcellular domains in differentiated vascular smooth muscle cells

scientific article

Troponin C in brain

scientific article published on November 20, 1975

Troponin organization on relaxed and activated thin filaments revealed by electron microscopy and three-dimensional reconstruction11Edited by W. Baumeister

article

Ultra short yeast tropomyosins show novel myosin regulation

scientific article

Visualization of caldesmon on smooth muscle thin filaments

article

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