List of works - Hisakazu Mihara

A New Optical Label-Free Biosensing Platform Based on a Metal−Insulator−Metal Structure

scientific article published on 01 April 2010

A Peptide-Cyclodextrin Hybrid System Capable of Detecting Guest Molecules Utilizing Fluorescence Resonance Energy Transfer

A chromism-based assay (CHROBA) technique for in situ detection of protein kinase activity

scientific article published on 01 March 2005

A monosaccharide-modified peptide phage library for screening of ligands to carbohydrate-binding proteins.

scientific article

A novel array format for monitoring cellular uptake using a photo-cleavable linker for peptide release.

scientific article published in July 2013

A novel β-loop scaffold of phage-displayed peptides for highly specific affinities.

scientific article

Affinity Control of Monosaccharide Conjugated Peptides against Lectins with a Set of Amino Acid Substitutions on α-Helical Structures

scientific article published on 20 October 2020

Affinity-based screening of peptides recognizing assembly states of self-assembling peptide nanomaterials

scientific article published in October 2009

Anomalous reflection of gold applicable for a practical protein-detecting chip platform.

scientific article published on 3 November 2005

Binding modes of the precursor of adenovirus major core protein VII to DNA and template activating factor I: implication for the mechanism of remodeling of the adenovirus chromatin.

scientific article published in January 2006

Cell fingerprint patterns using designed α-helical peptides to screen for cell-specific toxicity.

scientific article

Cell penetration and cell-selective drug delivery using α-helix peptides conjugated with gold nanoparticles.

scientific article published on 29 March 2013

Cell-selective intracellular drug delivery using doxorubicin and α-helical peptides conjugated to gold nanoparticles.

scientific article published on 15 January 2014

Cellular differentiation assessments by measuring the degree of cellular internalization and membrane adsorption using designed peptides.

scientific article published on 25 July 2014

Complementary Nucleobase Interaction Enhances Peptide–Peptide Recognition and Self‐Replicating Catalysis ⬇️

scientific article published on October 6, 2003

Construction of a chemically and conformationally self-replicating system of amyloid-like fibrils

scientific article published on 01 February 2004

Construction of a multi-functional extracellular matrix protein that increases number of N1E-115 neuroblast cells having neurites.

scientific article

Construction of a protein array on amyloid-like fibrils using co-assembly of designed peptides

scientific article published on 25 October 2004

Construction of biotinylated peptide nanotubes for arranging proteins

scientific article published on 24 June 2005

Construction of multi-functional extracellular matrix proteins that promote tube formation of endothelial cells.

scientific article

Construction of peptides with nucleobase amino acids: design and synthesis of the nucleobase-conjugated peptides derived from HIV-1 Rev and their binding properties to HIV-1 RRE RNA.

scientific article

Construction of proteins with molecular recognition capabilities using α3β3 de novo protein scaffolds.

scientific article

Construction of the novel conformationally-restricted peptide library for screening of peptides that control the interaction between nucleobases.

scientific article

Cyclic Peptides. XXII. Synthesis of [2-Amino-2,3-dehydrobutanoic Acid4]AM-Toxin I

scientific article published in June 1986

Cyclodextrin–peptide hybrid as a hydrolytic catalyst having multiple functional groups

scientific article published on 01 April 2000

De Novo Design of Peptides withl-α-Nucleobase Amino Acids and Their Binding Properties to the P22 boxB RNA and Its Mutants

scientific article published on 01 July 2004

Dense surface functionalization using peptides that recognize differences in organized structures of self-assembling nanomaterials.

scientific article

Desiccation-induced structuralization and glass formation of group 3 late embryogenesis abundant protein model peptides.

scientific article published in February 2010

Design and conformational analysis of natively folded β-hairpin peptides stabilized by nucleobase interactions.

scientific article published in January 2010

Design and synthesis of basic peptides having amphipathic β-structure and their interaction with phospholipid membranes

scientific article published on 01 February 1990

Design of peptides derived from anti-IgE antibody for allergic treatment

scientific article published on 01 August 1999

Design of peptides that form amyloid-like fibrils capturing amyloid beta1-42 peptides

scientific article

Design, synthesis and peroxidase-like activity of 3α-helix proteins covalently bound to heme

article

Design, synthesis, and conformation of a model peptide of endothelin with cystine-stabilized ?-helix motif

article

Designed Short Peptides that Form Amyloid-Like Fibrils in Coassembly with Amyloid β-Peptide (Aβ) Decrease the Toxicity of Aβ to Neuronal PC12 Cells

article

Dihydrofolate reductase inhibitory peptides screened from a structured designed β-loop peptide library displayed on phage

scientific article published on 29 June 2015

Effects of Group 3 LEA protein model peptides on desiccation-induced protein aggregation.

scientific article published on 8 May 2012

Embedding the amyloid beta-peptide sequence in green fluorescent protein inhibits Abeta oligomerization

scientific article published in June 2007

FRET detection of amyloid β-peptide oligomerization using a fluorescent protein probe presenting a pseudo-amyloid structure

scientific article published on 12 September 2011

Fabrication of nanofibers with uniform morphology by self-assembly of designed peptides.

scientific article published in June 2004

Fluorescence resonance energy transfer in a novel cyclodextrin-peptide conjugate for detecting steroid molecules

scientific article

Inhibition of peptide amyloid formation by cationic peptides with homologous sequences

scientific article published on 01 November 2003

Interaction of amphiphilic α-helical cell-penetrating peptides with heparan sulfate.

scientific article

Interactions between peptides containing nucleobase amino acids and T7 phages displaying S. cerevisiae proteins.

scientific article

Intracellular artificial supramolecules based on de novo designed Y15 peptides

scientific article published on 07 June 2021

Modification of a small β-barrel protein, to give pseudo-amyloid structures, inhibits amyloid β-peptide aggregation

scientific article

Mutational analysis of designed peptides that undergo structural transition from α helix to β sheet and amyloid fibril formation

article

Novel peptides bearing pyrene and coumarin units with or without beta-cyclodextrin in their side chains exhibit intramolecular fluorescence resonance energy transfer

scientific article

Optimization of Hydrophobic Domains in Peptides that Undergo Transformation from α-Helix to β-Fibril

scientific article published on 01 January 1999

Peptide and protein mimetics inhibiting amyloid beta-peptide aggregation.

scientific article

Peptide and protein synthesis by segment synthesis-condensation.

scientific article published in January 1989

Peptide arrays with designed alpha-helical structures for characterization of proteins from FRET fingerprint patterns.

scientific article published in January 2004

Peptide nanofibers modified with a protein by using designed anchor molecules bearing hydrophobic and functional moieties.

scientific article published in June 2010

Peptides as new smart bionanomaterials: molecular-recognition and self-assembly capabilities.

scientific article

Phosphate-mediated molecular memory driven by two different protein kinases as information input elements.

scientific article published on 9 June 2007

Poly(amidoamine)-dendrimer-modified gold surfaces for anomalous reflection of gold to detect biomolecular interactions.

scientific article published in April 2009

Protein-detecting microarrays: current accomplishments and requirements.

scientific article

Protein-fingerprint data mining of a designed alpha-helical peptide array

scientific article

Protein-protein interactions and selection: array-based techniques for screening disease-associated biomarkers in predictive/early diagnosis.

scientific article published on May 2010

RNA aptamers selected against amyloid beta-peptide (Abeta) inhibit the aggregation of Abeta

scientific article published on 28 May 2009

Rational design of homogenous protein kinase assay platforms that allow both fluorometric and colorimetric signal readouts

scientific article published on 25 September 2006

Relationship between antimicrobial activity and amphiphilic property of basic model peptides

article

Screening for concanavalin A binders from a mannose-modified α-helix peptide phage library

scientific article

Screening of alpha-helical peptide ligands controlling a calcineurin-phosphatase activity.

scientific article

Selection and structural analysis of de novo proteins from an alpha3beta3 genetic library

scientific article

Self-assembling peptide nanofibers promoting cell adhesion and differentiation.

scientific article published in November 2013

Sensitive Detection of Small Molecule-Protein Interactions on a Metal-Insulator-Metal Label-Free Biosensing Platform

article

Systematic screening of the cellular uptake of designed alpha-helix peptides.

scientific article

Utilization of L-alpha-nucleobase amino acids (NBAs) as protein engineering tools: construction of NBA-modified HIV-1 protease analogues and enhancement of dimerization induced by nucleobase interaction

scientific article published in May 2006

a high-throughput screening utilizing intramolecular fluorescence resonance energy transfer for the discovery of the molecules that bind hiv-1 tar rna specifically

article

List of works by Hisakazu Mihara

A New Optical Label-Free Biosensing Platform Based on a Metal−Insulator−Metal Structure

A Peptide-Cyclodextrin Hybrid System Capable of Detecting Guest Molecules Utilizing Fluorescence Resonance Energy Transfer

A chromism-based assay (CHROBA) technique for in situ detection of protein kinase activity

A monosaccharide-modified peptide phage library for screening of ligands to carbohydrate-binding proteins.

A novel array format for monitoring cellular uptake using a photo-cleavable linker for peptide release.

A novel β-loop scaffold of phage-displayed peptides for highly specific affinities.

Affinity Control of Monosaccharide Conjugated Peptides against Lectins with a Set of Amino Acid Substitutions on α-Helical Structures

Affinity-based screening of peptides recognizing assembly states of self-assembling peptide nanomaterials

Anomalous reflection of gold applicable for a practical protein-detecting chip platform.

Binding modes of the precursor of adenovirus major core protein VII to DNA and template activating factor I: implication for the mechanism of remodeling of the adenovirus chromatin.

Cell fingerprint patterns using designed α-helical peptides to screen for cell-specific toxicity.

Cell penetration and cell-selective drug delivery using α-helix peptides conjugated with gold nanoparticles.

Cell-selective intracellular drug delivery using doxorubicin and α-helical peptides conjugated to gold nanoparticles.

Cellular differentiation assessments by measuring the degree of cellular internalization and membrane adsorption using designed peptides.

Complementary Nucleobase Interaction Enhances Peptide–Peptide Recognition and Self‐Replicating Catalysis ⬇️

Construction of a chemically and conformationally self-replicating system of amyloid-like fibrils

Construction of a multi-functional extracellular matrix protein that increases number of N1E-115 neuroblast cells having neurites.

Construction of a protein array on amyloid-like fibrils using co-assembly of designed peptides

Construction of biotinylated peptide nanotubes for arranging proteins

Construction of multi-functional extracellular matrix proteins that promote tube formation of endothelial cells.

Construction of peptides with nucleobase amino acids: design and synthesis of the nucleobase-conjugated peptides derived from HIV-1 Rev and their binding properties to HIV-1 RRE RNA.

Construction of proteins with molecular recognition capabilities using α3β3 de novo protein scaffolds.

Construction of the novel conformationally-restricted peptide library for screening of peptides that control the interaction between nucleobases.

Cyclic Peptides. XXII. Synthesis of [2-Amino-2,3-dehydrobutanoic Acid4]AM-Toxin I

Cyclodextrin–peptide hybrid as a hydrolytic catalyst having multiple functional groups

De Novo Design of Peptides withl-α-Nucleobase Amino Acids and Their Binding Properties to the P22 boxB RNA and Its Mutants

Dense surface functionalization using peptides that recognize differences in organized structures of self-assembling nanomaterials.

Desiccation-induced structuralization and glass formation of group 3 late embryogenesis abundant protein model peptides.

Design and conformational analysis of natively folded β-hairpin peptides stabilized by nucleobase interactions.

Design and synthesis of basic peptides having amphipathic β-structure and their interaction with phospholipid membranes

Design of peptides derived from anti-IgE antibody for allergic treatment

Design of peptides that form amyloid-like fibrils capturing amyloid beta1-42 peptides

Design, synthesis and peroxidase-like activity of 3α-helix proteins covalently bound to heme

Design, synthesis, and conformation of a model peptide of endothelin with cystine-stabilized ?-helix motif

Designed Short Peptides that Form Amyloid-Like Fibrils in Coassembly with Amyloid β-Peptide (Aβ) Decrease the Toxicity of Aβ to Neuronal PC12 Cells

Dihydrofolate reductase inhibitory peptides screened from a structured designed β-loop peptide library displayed on phage

Effects of Group 3 LEA protein model peptides on desiccation-induced protein aggregation.

Embedding the amyloid beta-peptide sequence in green fluorescent protein inhibits Abeta oligomerization

FRET detection of amyloid β-peptide oligomerization using a fluorescent protein probe presenting a pseudo-amyloid structure

Fabrication of nanofibers with uniform morphology by self-assembly of designed peptides.

Fluorescence resonance energy transfer in a novel cyclodextrin-peptide conjugate for detecting steroid molecules

Inhibition of peptide amyloid formation by cationic peptides with homologous sequences

Interaction of amphiphilic α-helical cell-penetrating peptides with heparan sulfate.

Interactions between peptides containing nucleobase amino acids and T7 phages displaying S. cerevisiae proteins.

Intracellular artificial supramolecules based on de novo designed Y15 peptides

Modification of a small β-barrel protein, to give pseudo-amyloid structures, inhibits amyloid β-peptide aggregation

Mutational analysis of designed peptides that undergo structural transition from α helix to β sheet and amyloid fibril formation

Novel peptides bearing pyrene and coumarin units with or without beta-cyclodextrin in their side chains exhibit intramolecular fluorescence resonance energy transfer

Optimization of Hydrophobic Domains in Peptides that Undergo Transformation from α-Helix to β-Fibril

Peptide and protein mimetics inhibiting amyloid beta-peptide aggregation.

Peptide and protein synthesis by segment synthesis-condensation.

Peptide arrays with designed alpha-helical structures for characterization of proteins from FRET fingerprint patterns.

Peptide nanofibers modified with a protein by using designed anchor molecules bearing hydrophobic and functional moieties.

Peptides as new smart bionanomaterials: molecular-recognition and self-assembly capabilities.

Phosphate-mediated molecular memory driven by two different protein kinases as information input elements.

Poly(amidoamine)-dendrimer-modified gold surfaces for anomalous reflection of gold to detect biomolecular interactions.

Protein-detecting microarrays: current accomplishments and requirements.

Protein-fingerprint data mining of a designed alpha-helical peptide array

Protein-protein interactions and selection: array-based techniques for screening disease-associated biomarkers in predictive/early diagnosis.

RNA aptamers selected against amyloid beta-peptide (Abeta) inhibit the aggregation of Abeta

Rational design of homogenous protein kinase assay platforms that allow both fluorometric and colorimetric signal readouts

Relationship between antimicrobial activity and amphiphilic property of basic model peptides

Screening for concanavalin A binders from a mannose-modified α-helix peptide phage library

Screening of alpha-helical peptide ligands controlling a calcineurin-phosphatase activity.

Selection and structural analysis of de novo proteins from an alpha3beta3 genetic library

Self-assembling peptide nanofibers promoting cell adhesion and differentiation.

Sensitive Detection of Small Molecule-Protein Interactions on a Metal-Insulator-Metal Label-Free Biosensing Platform

Systematic screening of the cellular uptake of designed alpha-helix peptides.

Utilization of L-alpha-nucleobase amino acids (NBAs) as protein engineering tools: construction of NBA-modified HIV-1 protease analogues and enhancement of dimerization induced by nucleobase interaction

a high-throughput screening utilizing intramolecular fluorescence resonance energy transfer for the discovery of the molecules that bind hiv-1 tar rna specifically