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List of works by Andreas Spittler

A Th17- and Th2-skewed cytokine profile in cystic fibrosis lungs represents a potential risk factor for Pseudomonas aeruginosa infection.

scientific article

A compact and integrated immunoassay with on-chip dispensing and magnetic particle handling.

scientific article published in February 2016

A glutamine deficiency impairs the function of cultured human monocytes

scientific article published on 01 April 1997

Aberrant gut-microbiota-immune-brain axis development in premature neonates with brain damage

publication published on 03 September 2021

Accelerated Tryptophan Degradation Predicts Poor Survival in Trauma and Sepsis Patients ⬇️

scientific article published on June 10, 2010

Administration of a standardized plasma-protein solution (Biseko®) in high-risk patients with systemic inflammatory response syndrome: influence on cytokine levels and survival.

scientific article published on 13 March 2008

Administration of proteolytic enzymes bromelain and trypsin diminish the number of CD4+ cells and the interferon-gamma response in Peyer's patches and spleen in endotoxemic balb/c mice.

scientific article

Alterations in the number of circulating leucocytes, phenotype of monocyte and cytokine production in patients undergoing cardiothoracic surgery

scientific article published in February 1999

Artemisinins Target GABAA Receptor Signaling and Impair α Cell Identity

scientific article

Bedside Immune Monitoring: An Automated Immunoassay Platform for Quantification of Blood Biomarkers in Patient Serum within 20 Minutes.

scientific article published on 6 April 2017

CL097, a TLR7/8 ligand, inhibits TLR-4--dependent activation of IRAK-M and BCL-3 expression.

scientific article published in November 2009

Changes in Circulating Extracellular Vesicles in Patients with ST-Elevation Myocardial Infarction and Potential Effects of Remote Ischemic Conditioning-A Randomized Controlled Trial

scientific article published on 16 July 2020

Characterization of extracellular vesicles in whole blood: Influence of pre-analytical parameters and visualization of vesicle-cell interactions using imaging flow cytometry.

scientific article published on 18 July 2016

Chemotherapy of colorectal liver metastases induces a rapid rise in intermediate blood monocytes which predicts treatment response

scientific article published on 22 March 2016

Clazakizumab in late antibody-mediated rejection: study protocol of a randomized controlled pilot trial

scientific article published on 11 January 2019

Clinical outcome of critically ill patients cannot be defined by cutoff values of monocyte human leukocyte antigen-DR expression

scientific article published on 01 February 2012

Cord blood derived CD4+ CD25(high) T cells become functional regulatory T cells upon antigen encounter

scientific article

Coupling of a Major Allergen to the Surface of Immune Cells for Use in Prophylactic Cell Therapy for the Prevention of IgE-Mediated Allergy

scientific article published in 2024

Decreased phagocytic capacity of cord blood monocytes in second- and third-born multiplets

scientific article published on 01 January 2002

Different Potential of Extracellular Vesicles to Support Thrombin Generation: Contributions of Phosphatidylserine, Tissue Factor, and Cellular Origin

scientific article published on 26 July 2017

Differential Interaction of Platelet-Derived Extracellular Vesicles with Leukocyte Subsets in Human Whole Blood.

scientific article published on 26 April 2018

Diminished secretion and function of IL-29 is associated with impaired IFN-α response of neonatal plasmacytoid dendritic cells

scientific article published on 18 June 2019

EVI1 promotes tumor growth via transcriptional repression of MS4A3.

scientific article published on 21 March 2015

Early increase of plasma homocysteine in sepsis patients with poor outcome

scientific article

Effect of hemoadsorption during cardiopulmonary bypass surgery - a blinded, randomized, controlled pilot study using a novel adsorbent

scientific article published on 9 April 2016

Effect of single and combined supply of glutamine, glycine, N-acetylcysteine, and R,S-alpha-lipoic acid on glutathione content of myelomonocytic cells.

scientific article published in December 2003

Effects of dental amalgam and heavy metal cations on cytokine production by peripheral blood mononuclear cellsin vitro

scientific article published on 01 October 1998

Elevated serum levels of epithelial cell apoptosis-specific cytokeratin 18 neoepitope m30 in critically ill patients

scientific article published on 01 September 2004

Endothelial cells of extremely premature infants display impaired immune response after proinflammatory stimulation.

scientific article

Evidence for a Role of TGF-β-Activated Kinase 1 and MAP3K7 Binding Protein 3 in Peanut-Specific T-Cell Responses

scientific article published on 20 March 2019

Expansion of BCR/ABL1+ cells requires PAK2 but not PAK1.

scientific article published on 14 July 2017

Folate Receptor β Regulates Integrin CD11b/CD18 Adhesion of a Macrophage Subset to Collagen.

scientific article published on 17 August 2016

Functional and Transcriptomic Characterization of Peritoneal Immune-Modulation by Addition of Alanyl-Glutamine to Dialysis Fluid.

scientific article published on 24 July 2017

GM-CSF Down-Regulates TLR Expression via the Transcription Factor PU.1 in Human Monocytes

scientific article

Glutamine deficiency renders human monocytic cells more susceptible to specific apoptosis triggers.

scientific article published in January 2002

Glutamine starvation of monocytes inhibits the ubiquitin-proteasome proteolytic pathway

scientific article

HIF1α Regulates mTOR Signaling and Viability of Prostate Cancer Stem Cells

scientific article

HO-1 inhibits preadipocyte proliferation and differentiation at the onset of obesity via ROS dependent activation of Akt2.

scientific article published on 19 January 2017

Hematopoietic stem cells in neonates: any differences between very preterm and term neonates?

scientific article

Human NK cells express Fc receptors for IgA which mediate signal transduction and target cell killing.

scientific article published in August 2003

Human lactoferrin attenuates the proinflammatory response of neonatal monocyte-derived macrophages

scientific article

IL-10 augments CD23 expression on U937 cells and down-regulates IL-4-driven CD23 expression on cultured human blood monocytes: effects of IL-10 and other cytokines on cell phenotype and phagocytosis ⬇️

scientific article published on June 1, 1995

IL-33 stimulates the release of procoagulant microvesicles from human monocytes and differentially increases tissue factor in human monocyte subsets

scientific article published on 11 May 2017

Immaturity of infection control in preterm and term newborns is associated with impaired toll-like receptor signaling.

scientific article published in December 2006

Immune monitoring in cardiac transplant recipients

scientific article published on 01 November 1997

Immunomodulation to Prevent or Treat Neonatal Sepsis: Past, Present, and Future

scientific article published on 19 July 2018

Immunomodulatory effects of glycine on LPS-treated monocytes: reduced TNF-alpha production and accelerated IL-10 expression

scientific article published on 01 March 1999

Inadequate production of hematopoietic growth factors in hairy cell leukemia: up-regulation of interleukin 6 by recombinant IFN-alpha in vitro

scientific article published on 01 October 1996

Influence of an immunoglobulin-enriched (IgG, IgA, IgM) solution on activation and immunomodulatory functions of peripheral blood mononuclear cells in a LPS second-hit model

Influence of dental amalgam and heavy metal cations on in vitro interleukin-1beta production by human peripheral blood mononuclear cells

scientific article published on 01 July 2000

Influence of enteral diets supplemented with key nutrients on lymphocyte subpopulations in Peyer's patches of endotoxin-boostered mice

scientific article published on 01 August 2000

Influence of fructooligosaccharides on Peyer's patch lymphocyte numbers in healthy and endotoxemic mice

scientific article published on 01 July 2003

Influence of glutamine on the phenotype and function of human monocytes

scientific article

Influence of heat shock on cell volume regulation: protection from hypertonic challenge in a human monocyte cell line.

scientific article published on May 1998

Influence of short-term protein malnutrition of mice on the phenotype and costimulatory signals of lymphocytes from spleen and Peyer's patches

scientific article published on 01 March 2000

Influence of suramin on the expression of Fc receptors and other markers on human monocytes and U937 cells, and on their phagocytic properties.

scientific article published on April 1994

Influence of tumour necrosis factor-alpha on the expression of Fc IgG and IgA receptors, and other markers by cultured human blood monocytes and U937 cells.

scientific article published on February 1994

Influenza a virus induces an immediate cytotoxic activity in all major subsets of peripheral blood mononuclear cells

scientific article

Is monocyte HLA-DR expression predictive for clinical outcome in sepsis?

scientific article published on 01 August 2003

Isolation, cultivation, and characterization of human mesenchymal stem cells.

scientific article published on 26 October 2017

Lipopolysaccharide causes atrophy of Peyer's patches and an increased expression of CD28 and B7 costimulatory ligands

scientific article published on 01 October 2000

Lipopolysaccharide-induced tumor necrosis factor alpha production and not monocyte human leukocyte antigen-DR expression is correlated with survival in septic trauma patients

article by Martin Ploder et al published 1 February 2006 in Shock

Low Glutamine Concentrations Induce Phenotypical and Functional Differentiation of U937 Myelomonocytic Cells , ⬇️

scientific article published on November 1, 1997

MSH3-deficiency initiates EMAST without oncogenic transformation of human colon epithelial cells

scientific article

Macrophage-derived IL-33 is a critical factor for placental growth

scientific article published on 30 August 2013

Modulation of IgA, IgE, and IgG Fc receptor expression on human mononuclear phagocytes by 1 alpha,25-dihydroxyvitamin D3 and cytokines.

scientific article published on August 1995

Modulation of toll-like receptor 4 expression on human monocytes by tumor necrosis factor and interleukin-6: tumor necrosis factor evokes lipopolysaccharide hyporesponsiveness, whereas interleukin-6 enhances lipopolysaccharide activity.

scientific article

Molecular and cellular effects of in vitro shockwave treatment on lymphatic endothelial cells

scientific article published on 11 December 2014

Monitoring temporary immunodepression by flow cytometric measurement of monocytic HLA-DR expression: a multicenter standardized study

scientific article published on 7 October 2005

Monocyte phagocytosis as a reliable parameter for predicting early-onset sepsis in very low birthweight infants

scientific article published on 01 April 2002

Monocytes do not make mast cells when cultured in the presence of SCF. Characterization of the circulating mast cell progenitor as a c-kit+, CD34+, Ly-, CD14-, CD17-, colony-forming cell

scientific article published on 01 October 1993

Oral feeding with glutamine prevents lymphocyte and glutathione depletion of Peyer's patches in endotoxemic mice

scientific article

Pentoxifylline modulates LPS-induced hyperinflammation in monocytes of preterm infants in vitro.

scientific article published on 13 March 2017

Perioperative GLY-GLN infusion diminishes the surgery-induced period of immunosuppression: accelerated restoration of the lipopolysaccharide-stimulated tumor necrosis factor-alpha response.

scientific article

Peripheral blood microvesicles secretion is influenced by storage time, temperature, and anticoagulants.

scientific article published on July 2016

Polytrauma induces increased expression of pyruvate kinase in neutrophils

scientific article published on 01 February 2000

Postoperative glycyl-glutamine infusion reduces immunosuppression: partial prevention of the surgery induced decrease in HLA-DR expression on monocytes.

scientific article

Potential role of platelet-leukocyte aggregation in trauma-induced coagulopathy: Ex vivo findings.

scientific article published on 2 March 2017

Preterm neonates display altered plasmacytoid dendritic cell function and morphology.

scientific article

Procoagulant extracellular vesicles in amniotic fluid

scientific article

Purification of human basophils and mast cells by multistep separation technique and mAb to CDw17 and CD117/c-kit

scientific article published on 01 May 1995

Receptor and non-receptor mediated formation of superoxide anion and hydrogen peroxide in neutrophils of intensive care patients

scientific article published on 01 November 1998

Reduced TNF-α response in preterm neonates is associated with impaired nonclassic monocyte function.

scientific article published on 10 March 2016

Regulation of cytokine production in human peripheral blood mononuclear cells and allergen-specific th cell clones by 1alpha,25-dihydroxyvitamin D3.

scientific article published in May 2002

Regulative potential of glutamine--relation to glutathione metabolism.

scientific article

Relationship between interleukin-6 plasma concentration in patients with sepsis, monocyte phenotype, monocyte phagocytic properties, and cytokine production

scientific article published on 22 November 2000

Release and cellular origin of extracellular vesicles during circulation of whole blood over adsorbent polymers for lipid apheresis.

scientific article published on 16 December 2015

Serum phenylalanine in patients post trauma and with sepsis correlate to neopterin concentrations.

scientific article published on 28 December 2007

Serum-dependent processing of late apoptotic cells for enhanced efferocytosis.

scientific article

Severe acute pancreatitis causes alterations in HLA-DR and CD14 expression on peripheral blood monocytes independently of surgical treatment

scientific article published on 01 August 2000

Single-cell transcriptomes reveal characteristic features of human pancreatic islet cell types

scientific article published on 21 December 2015

The Proteome of Extracellular Vesicles Released from Pulmonary Microvascular Endothelium Reveals Impact of Oxygen Conditions on Biotrauma

scientific article published in 2024

The TLR-specific adjuvants R-848 and CpG-B endorse the immunological reaction of neonatal antigen-presenting cells

scientific article published on 8 April 2016

The combined use of known antiviral reverse transcriptase inhibitors AZT and DDI induce anticancer effects at low concentrations.

scientific article

The cyclooxygenase-2 inhibitor nimesulide, a nonsteroidal analgesic, decreases the effect of radiation therapy in head-and-neck cancer cells

scientific article

The novel polyclonal Ab preparation trimodulin attenuates ex vivo endotoxin-induced immune reactions in early hyperinflammation

scientific article published on 04 June 2019

The oncogene EVI1 enhances transcriptional and biological responses of human myeloid cells to all-trans retinoic acid

scientific article published on January 2014

The role of Foxp3+ T cells in long-term efficacy of prophylactic and therapeutic mucosal tolerance induction in mice.

scientific article published on February 2006

Thrombocyte Adhesion and Release of Extracellular Microvesicles Correlate with Surface Morphology of Adsorbent Polymers for Lipid Apheresis

scientific article published on 30 May 2014

Tumor necrosis factor-alpha induction of major histocompatibility complex class II antigen expression is inhibited by interferon-gamma in a monocytic cell line.

scientific article published on November 1995

Vitamin D3 down-regulates monocyte TLR expression and triggers hyporesponsiveness to pathogen-associated molecular patterns.

scientific article published in February 2006

[Glutamine: effects on the immune system, protein balance and intestinal functions]

scientific article published on 01 January 1996

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