List of works - Stéphane Zaffran

Direct isolation of satellite cells for skeletal muscle regeneration

scientific article published in September 2005

Building the mammalian heart from two sources of myocardial cells

scientific article (publication date: November 2005)

Pax3 and Pax7 have distinct and overlapping functions in adult muscle progenitor cells.

scientific article

Right ventricular myocardium derives from the anterior heart field

scientific article

Fgf10 expression identifies parabronchial smooth muscle cell progenitors and is required for their entry into the smooth muscle cell lineage

scientific journal article

Early signals in cardiac development.

scientific article

Retinoic acid deficiency alters second heart field formation.

scholarly article

Rotation of the myocardial wall of the outflow tract is implicated in the normal positioning of the great arteries

scientific article published on 5 January 2006

Atrial myocardium derives from the posterior region of the second heart field, which acquires left-right identity as Pitx2c is expressed.

scientific article

Early cardiac development: a view from stem cells to embryos

scientific article

Fibroblast growth factor 10 gene regulation in the second heart field by Tbx1, Nkx2-5, and Islet1 reveals a genetic switch for down-regulation in the myocardium.

scientific article

Hox genes define distinct progenitor sub-domains within the second heart field.

scientific article

Cardioblast-intrinsic Tinman activity controls proper diversification and differentiation of myocardial cells in Drosophila.

scientific article published on 20 September 2006

Endogenous retinoic acid regulates cardiac progenitor differentiation.

scientific article

Tbx1 coordinates addition of posterior second heart field progenitor cells to the arterial and venous poles of the heart.

scientific article published on 4 September 2014

Congenital heart defects in Fgfr2-IIIb and Fgf10 mutant mice

scientific journal article

Decreased levels of embryonic retinoic acid synthesis accelerate recovery from arterial growth delay in a mouse model of DiGeorge syndrome

scientific article

New developments in the second heart field.

scientific article published on 21 April 2012

Myocardium at the base of the aorta and pulmonary trunk is prefigured in the outflow tract of the heart and in subdomains of the second heart field

scientific article published on 22 September 2007

Expression of Slit and Robo genes in the developing mouse heart.

scientific article

ISL1 directly regulates FGF10 transcription during human cardiac outflow formation

scientific article

Mechanisms of retinoic acid signaling during cardiogenesis

scientific article published on 19 December 2016

Value of in vivo T2 measurement for myocardial fibrosis assessment in diabetic mice at 11.75 T.

scientific article published in May 2012

Hoxb1 regulates proliferation and differentiation of second heart field progenitors in pharyngeal mesoderm and genetically interacts with Hoxa1 during cardiac outflow tract development

scientific article

Disruption of CXCR4 signaling in pharyngeal neural crest cells causes DiGeorge syndrome-like malformations.

scientific article published on 11 January 2016

Cellular interactions during heart morphogenesis in the Drosophila embryo

scientific article published in January 1995

Cardiogenesis in the Drosophila model: control mechanisms during early induction and diversification of cardiac progenitors

scientific article published in January 2002

The Drosophila Hand gene is required for remodeling of the developing adult heart and midgut during metamorphosis

scientific article

Krox20 defines a subpopulation of cardiac neural crest cells contributing to arterial valves and bicuspid aortic valve.

scientific article published on 20 November 2017

A retinoic acid responsive Hoxa3 transgene expressed in embryonic pharyngeal endoderm, cardiac neural crest and a subdomain of the second heart field

scientific article

The homeodomain of Tinman mediates homo- and heterodimerization of NK proteins

scientific article published in August 2005

Conotruncal defects associated with anomalous pulmonary venous connections

scientific article published on 25 February 2009

The alternatively spliced LRRFIP1 Isoform-1 is a key regulator of the Wnt/β-catenin transcription pathway

scientific article

Cell history determines the maintenance of transcriptional differences between left and right ventricular cardiomyocytes in the developing mouse heart.

scientific article published in December 2003

Cardiac outflow morphogenesis depends on effects of retinoic acid signaling on multiple cell lineages

scientific article published on 28 October 2015

Hoxa1 and Hoxb1 are required for pharyngeal arch artery development.

scientific article published on 9 December 2016

Loss of Krox20 results in aortic valve regurgitation and impaired transcriptional activation of fibrillar collagen genes.

scientific article published on 24 October 2014

Hox Genes in Cardiovascular Development and Diseases.

scientific article published on 24 March 2016

T-box genes and retinoic acid signaling regulate the segregation of arterial and venous pole progenitor cells in the murine second heart field

article

Actionable Genes, Core Databases, and Locus-Specific Databases.

scientific article

Bmp2 and Notch cooperate to pattern the embryonic endocardium

scientific article published on 02 July 2018

Asb2α-Filamin A Axis Is Essential for Actin Cytoskeleton Remodeling During Heart Development

scientific article published on 26 January 2018

Msx1CreERT2 knock-In allele: A useful tool to target embryonic and adult cardiac valves

scientific article published in May 2015

Reduced aggrecan expression affects cardiac outflow tract development in zebrafish and is associated with bicuspid aortic valve disease in humans

scientific article

Genetic lineage tracing analysis of anterior Hox expressing cells

scientific article published in January 2014

WES/WGS Reporting of Mutations from Cardiovascular "Actionable" Genes in Clinical Practice: A Key Role for UMD Knowledgebases in the Era of Big Databases

scientific article published on 20 September 2016

Human pre-valvular endocardial cells derived from pluripotent stem cells recapitulate cardiac pathophysiological valvulogenesis

scientific article published on 26 April 2019

Giant congenital melanocytic nevus with vascular malformation and epidermal cysts associated with a somatic activating mutation in BRAF.

scientific article published on 5 January 2018

Ectopic expression of Hoxb1 induces cardiac and craniofacial malformations

scientific article published on 01 June 2018

Hox and Tale transcription factors in heart development and disease

scientific article published on 01 January 2018

List of works by Stéphane Zaffran

Direct isolation of satellite cells for skeletal muscle regeneration

Building the mammalian heart from two sources of myocardial cells

Pax3 and Pax7 have distinct and overlapping functions in adult muscle progenitor cells.

Right ventricular myocardium derives from the anterior heart field

Fgf10 expression identifies parabronchial smooth muscle cell progenitors and is required for their entry into the smooth muscle cell lineage

Early signals in cardiac development.

Retinoic acid deficiency alters second heart field formation.

Rotation of the myocardial wall of the outflow tract is implicated in the normal positioning of the great arteries

Atrial myocardium derives from the posterior region of the second heart field, which acquires left-right identity as Pitx2c is expressed.

Early cardiac development: a view from stem cells to embryos

Fibroblast growth factor 10 gene regulation in the second heart field by Tbx1, Nkx2-5, and Islet1 reveals a genetic switch for down-regulation in the myocardium.

Hox genes define distinct progenitor sub-domains within the second heart field.

Cardioblast-intrinsic Tinman activity controls proper diversification and differentiation of myocardial cells in Drosophila.

Endogenous retinoic acid regulates cardiac progenitor differentiation.

Tbx1 coordinates addition of posterior second heart field progenitor cells to the arterial and venous poles of the heart.

Congenital heart defects in Fgfr2-IIIb and Fgf10 mutant mice

Decreased levels of embryonic retinoic acid synthesis accelerate recovery from arterial growth delay in a mouse model of DiGeorge syndrome

New developments in the second heart field.

Myocardium at the base of the aorta and pulmonary trunk is prefigured in the outflow tract of the heart and in subdomains of the second heart field

Expression of Slit and Robo genes in the developing mouse heart.

ISL1 directly regulates FGF10 transcription during human cardiac outflow formation

Mechanisms of retinoic acid signaling during cardiogenesis

Value of in vivo T2 measurement for myocardial fibrosis assessment in diabetic mice at 11.75 T.

Hoxb1 regulates proliferation and differentiation of second heart field progenitors in pharyngeal mesoderm and genetically interacts with Hoxa1 during cardiac outflow tract development

Disruption of CXCR4 signaling in pharyngeal neural crest cells causes DiGeorge syndrome-like malformations.

Cellular interactions during heart morphogenesis in the Drosophila embryo

Cardiogenesis in the Drosophila model: control mechanisms during early induction and diversification of cardiac progenitors

The Drosophila Hand gene is required for remodeling of the developing adult heart and midgut during metamorphosis

Krox20 defines a subpopulation of cardiac neural crest cells contributing to arterial valves and bicuspid aortic valve.

A retinoic acid responsive Hoxa3 transgene expressed in embryonic pharyngeal endoderm, cardiac neural crest and a subdomain of the second heart field

The homeodomain of Tinman mediates homo- and heterodimerization of NK proteins

Conotruncal defects associated with anomalous pulmonary venous connections

The alternatively spliced LRRFIP1 Isoform-1 is a key regulator of the Wnt/β-catenin transcription pathway

Cell history determines the maintenance of transcriptional differences between left and right ventricular cardiomyocytes in the developing mouse heart.

Cardiac outflow morphogenesis depends on effects of retinoic acid signaling on multiple cell lineages

Hoxa1 and Hoxb1 are required for pharyngeal arch artery development.

Loss of Krox20 results in aortic valve regurgitation and impaired transcriptional activation of fibrillar collagen genes.

Hox Genes in Cardiovascular Development and Diseases.

T-box genes and retinoic acid signaling regulate the segregation of arterial and venous pole progenitor cells in the murine second heart field

Actionable Genes, Core Databases, and Locus-Specific Databases.

Bmp2 and Notch cooperate to pattern the embryonic endocardium

Asb2α-Filamin A Axis Is Essential for Actin Cytoskeleton Remodeling During Heart Development

Msx1CreERT2 knock-In allele: A useful tool to target embryonic and adult cardiac valves

Reduced aggrecan expression affects cardiac outflow tract development in zebrafish and is associated with bicuspid aortic valve disease in humans

Genetic lineage tracing analysis of anterior Hox expressing cells

WES/WGS Reporting of Mutations from Cardiovascular "Actionable" Genes in Clinical Practice: A Key Role for UMD Knowledgebases in the Era of Big Databases

Human pre-valvular endocardial cells derived from pluripotent stem cells recapitulate cardiac pathophysiological valvulogenesis

Giant congenital melanocytic nevus with vascular malformation and epidermal cysts associated with a somatic activating mutation in BRAF.

Ectopic expression of Hoxb1 induces cardiac and craniofacial malformations

Hox and Tale transcription factors in heart development and disease