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List of works by Hiroyuki Koshino

1H, 13C and 77Se NMR study of tetraselenafulvalene derivatives supported by novel H(Se)C and H(C)Se triple-resonance experiments at natural abundance

scientific article published on 01 February 2008

2,3,5-Trichloro-4-methoxy-6-[2,3,5-trichloro-4-methoxy-6-(2,3,5,6-tetrachloro-4-methoxyphenoxy)phenoxy]phenol

2,3-Dihydrohomofarnesal: female sex attractant pheromone component of Callosobruchus rhodesianus (Pic).

scientific article published on 6 July 2010

4-Hydroxy-17-methylincisterol, an inhibitor of DNA polymerase-alpha activity and the growth of human cancer cells in vitro

scientific article published on 01 September 1998

A Highly Active 4-Siloxyproline Catalyst for Asymmetric Synthesis

A diterpene as an endogenous signal for the activation of defense responses to infection with tobacco mosaic virus and wounding in tobacco.

scientific article published in April 2003

A furanoid labdane diterpene from Potamogeton nodosus

scientific article published on 01 January 1998

A novel inhibitor for Fe-type nitrile hydratase: 2-cyano-2-propyl hydroperoxide.

scientific article published in September 2003

A three-component approach to isoquinoline derivatives by cycloaddition/Heck reaction sequence

AN483, a new anti-MRSA compound from Streptomyces sp. ⬇️

scientific article published on 14 January 2016

Absolute Configuration of Kelsoene and Prespatane

scientific article published on 01 January 1999

Algorithm for advanced canonical coding of planar chemical structures that considers stereochemical and symmetric information

scientific article published on 18 July 2007

Analyses of carbohydrate binding property of lectin-chaperone calreticulin.

scientific article published on 12 October 2007

Anti-inflammatory effects and specificity of L-156,602: comparison of effects on concanavalin A and zymosan-induced footpad edema, and contact sensitivity response

scientific article published on 01 February 1995

Antibacterial diterpenes and their fatty acid conjugates from rice leaves

scientific article

Betulinans A and B, two benzoquinone compounds from Lenzites betulina

scientific article published on 01 November 1996

Biosynthesis of isonitrile lipopeptides by conserved nonribosomal peptide synthetase gene clusters in Actinobacteria.

scientific article published on 20 June 2017

Botcinins A, B, C, and D, Metabolites Produced byBotrytiscinerea, and Their Antifungal Activity againstMagnaporthegrisea, a Pathogen of Rice Blast Disease

scientific article published on 26 December 2005

Botcinins E and F and Botcinolide fromBotrytiscinereaand Structural Revision of Botcinolides

scientific article published on 28 April 2006

Characterization of short-chain poly3-hydroxybutyrate in baker's yeast

scientific article

Chemical structure elucidation from ¹³C NMR chemical shifts: efficient data processing using bipartite matching and maximal clique algorithms.

scientific article

Chemically Locked Bicelles with High Thermal and Kinetic Stability.

scientific article published on 16 September 2015

Cleavage mechanism and anti-tumor activity of 3,6-epidioxy-1,10-bisaboladiene isolated from edible wild plants.

scientific article published on 17 April 2012

Convenient Synthesis of Thiohydantoins, Imidazole-2-thiones and Imidazo[2,1-b]thiazol-4-iums from Polymer-Supported α-Acylamino Ketones.

scientific article published on 23 April 2018

Convergent Synthesis of the ent-ZA'B'C'D'-Ring System of Maitotoxin

scientific article published in June 2017

Convergent synthesis of pyragonicin

scientific article published on 01 August 2006

Correction: The value of universally available raw NMR data for transparency, reproducibility, and integrity in natural product research

scientific article published on 23 November 2018

Coupling reaction of indolepyruvic acid by StaD and its product: implications for biosynthesis of indolocarbazole and violacein

scientific article published on 18 October 2012

Creation of novel reveromycin derivatives by alcohol-added fermentation.

scientific article published on 12 December 2012

Cucumis sativus secretes 4'-ketoriboflavin under iron-deficient conditions.

scientific article published on 2 November 2015

Cytoprotective Effects of Lysophospholipids from Sea Cucumber Holothuria atra.

scientific article published on 14 August 2015

Cytoxazone: A Novel Cytokine Modulator Containing a 2-Oxazolidinone Ring Produced by Streptomyces sp

scientific article published in February 1999

Design and synthesis of a vialinin A analog with a potent inhibitory activity of TNF-α production and its transformation into a couple of bioprobes

scientific article

Detection of oxygen addition peaks for terpendole E and related indole-diterpene alkaloids in a positive-mode ESI-MS.

scientific article published on June 2014

Determination of absolute structure of macroviracins by chemical synthesis

scientific article published on 01 May 2003

Disclosure of the "fairy" of fairy-ring-forming fungus Lepista sordida

scientific article

Easy Preparation of Methyl 7-epi-Jasmonate and Four Stereoisomers of Methyl Cucurbate, and Assessment of the Stereogenic Effect of Jasmonate on Phytohormonal Activities

scientific article published on 01 January 1999

Enantiomeric purity and odor characteristics of 2- and 3-acetoxy-1, 8-cineoles in the rhizomes of Alpinia galanga willd

scientific article published on 01 February 1999

Endoplasmic reticulum (ER) stress protecting compounds from the mushroom Mycoleptodonoides aitchisonii

Enzymatic synthesis of an α-chitin-like substance via lysozyme-mediated transglycosylation.

scientific article

Enzymatic synthesis of cellulose II-like substance via cellulolytic enzyme-mediated transglycosylation in an aqueous medium.

scientific article

Epoxyquinol A, a highly functionalized pentaketide dimer with antiangiogenic activity isolated from fungal metabolites.

scientific article

Epoxytwinol A, a novel unique angiogenesis inhibitor with C2 symmetry, produced by a fungus.

scientific article published on 15 March 2005

Evidence for endocyclic cleavage of conformationally restricted glycopyranosides.

scientific article published in July 2009

Expeditious synthesis of vialinin B, an extremely potent inhibitor of TNF-alpha production

scientific article published on 01 November 2009

Experimental evidence of distance-dependent diffusion coefficients of a globular protein observed in polymer aqueous solution forming a network structure on nanometer scale.

scientific article published in December 2004

First total synthesis of vialinin A, a novel and extremely potent inhibitor of TNF-alpha production

scientific article published on 12 September 2007

Flavimycins A and B, dimeric 1,3-dihydroisobenzofurans with peptide deformylase inhibitory activity from Aspergillus flavipes.

scientific article published on 13 February 2012

Fusarium Tri4 encodes a key multifunctional cytochrome P450 monooxygenase for four consecutive oxygenation steps in trichothecene biosynthesis.

scientific article published on 12 December 2006

Gene encoding the hydrolase for the product of the meta-cleavage reaction in testosterone degradation by Comamonas testosteroni.

scientific article

H(C)P and H(P)C triple-resonance experiments at natural abundance employing long-range couplings

scientific article published in September 2007

Hitoyol A and B, Two Norsesquiterpenoids from the Basidiomycete Coprinopsis cinerea

scientific article published on 20 July 2017

Hydroxylations of trichothecene rings in the biosynthesis of Fusarium trichothecenes: evolution of alternative pathways in the nivalenol chemotype.

scientific article published on 27 April 2016

Identification of 9,17-dioxo-1,2,3,4,10,19-hexanorandrostan-5-oic acid, 4-hydroxy-2-oxohexanoic acid, and 2-hydroxyhexa-2,4-dienoic acid and related enzymes involved in testosterone degradation in Comamonas testosteroni TA441.

scientific article

Identification of 9α-hydroxy-17-oxo-1,2,3,4,10,19-hexanorandrost-6-en-5-oic acid and β-oxidation products of the C-17 side chain in cholic acid degradation by Comamonas testosteroni TA441.

scientific article published on 5 May 2014

Identification of 9α-hydroxy-17-oxo-1,2,3,4,10,19-hexanorandrostan-5-oic acid in steroid degradation by Comamonas testosteroni TA441 and its conversion to the corresponding 6-en-5-oyl coenzyme A (CoA) involving open reading frame 28 (ORF28)- and ORF

scientific article

Identification of a new N-nitrosodimethylamine precursor in sewage containing industrial effluents.

scientific article

Identification of a novel factor, vanillyl benzyl ether, which inhibits somatic embryogenesis of Japanese larch (Larix leptolepis Gordon).

scientific article published on 2 February 2005

Identification of genes involved in inversion of stereochemistry of a C-12 hydroxyl group in the catabolism of cholic acid by Comamonas testosteroni TA441.

scientific article published on 6 June 2008

Identification of novel oxidized levuglandin D2 in marine red alga and mouse tissue ⬇️

scientific article published on September 5, 2011

Identification of the kinanthraquinone biosynthetic gene cluster by expression of an atypical response regulator ⬇️

scientific article published on 6 February 2021

Increased metabolite production by deletion of an HDA1-type histone deacetylase in the phytopathogenic fungi, Magnaporthe oryzae (Pyricularia oryzae) and Fusarium asiaticum.

scientific article

Inhibition of glycogen synthase kinase-3β by falcarindiol isolated from Japanese Parsley (Oenanthe javanica).

scientific article published on 29 July 2013

Inhibition of protein SUMOylation by davidiin, an ellagitannin from Davidia involucrata.

scientific article published on 15 January 2014

Inhibitory activity of Brazilian green propolis components and their derivatives on the release of cys-leukotrienes.

scientific article

Inhibitory activity of linoleic acid isolated from proso and Japanese millet toward histone deacetylase

scientific article published on 7 August 2007

Inhibitory effects of vialinin A and its analog on tumor necrosis factor-α release and production from RBL-2H3 cells

scientific article published on 29 October 2012

Isolation and characterization of a humoral factor that stimulates transcription of the acyl-CoA-binding protein in the pheromone gland of the silkmoth, Bombyx mori.

scientific article published on 6 December 2004

Isolation and structure determination of complexed poly(3-hydroxyalkanoate) from beet (Beta vulgaris L.).

scientific article published in September 2005

Isolation of Coralmycins A and B, Potent Anti-Gram Negative Compounds from the Myxobacteria Corallococcus coralloides M23.

scientific article

Isolation of Some Glucosides as Aroma Precursors from Ginger ⬇️

scientific article published on 01 January 1999

Kinetically Controlled One-Pot Formation of DEFGH-Rings of Type B Physalins through Domino-Type Transformations

scientific article published on 15 June 2012

Large nonlinear effect observed in the enantiomeric excess of proline in solution and that in the solid state

scientific article published in July 2006

Lucidenic acid O and lactone, new terpene inhibitors of eukaryotic DNA polymerases from a basidiomycete, Ganoderma lucidum

scientific article published on 01 September 1999

N(1), N(14)-diferuloylspermine as an antioxidative phytochemical contained in leaves of Cardamine fauriei.

scientific article

Nematicidal alkaloids and related compounds produced by the fungus Penicillium cf. simplicissimum ⬇️

scientific article published on 01 December 2000

Neomacrophorin X, a [4.4.3]Propellane-Type Meroterpenoid from Trichoderma sp. 1212-03.

scientific article published on 26 April 2017

New indole derivatives with free radical scavenging activity from Agrocybe cylindracea

scientific article published on 01 July 1997

Novel Distance Dependence of Diffusion Constants in Hyaluronan Aqueous Solution Resulting from Its Characteristic Nano-Microstructure ⬇️

scientific article published on November 21, 2001

Novel antifungal compounds produced by Sterile Dark, an unidentified wheat rhizosphere fungus.

scientific article published in May 2005

Novel canonical coding method for representation of three-dimensional structures

scientific article published on 01 May 2000

Novel catalytic activity of nitrile hydratase from Rhodococcus sp. N771.

scientific article

ORF18-disrupted mutant of Comamonas testosteroni TA441 accumulates significant amounts of 9,17-dioxo-1,2,3,4,10,19-hexanorandrostan-5-oic acid and its derivatives after incubation with steroids

scientific article published on 07 August 2006

One-pot synthesis of (-)-oseltamivir and mechanistic insights into the organocatalyzed Michael reaction.

scientific article published on 18 November 2013

Parvitexins A-E, clerodane-type diterpenes isolated from the in vitro-cultured liverwort, Scapania parvitexta

scientific article published on 07 November 2007

Peanut-skin polyphenols, procyanidin A1 and epicatechin-(4 β → 6)-epicatechin-(2 β → O → 7, 4 β → 8)-catechin, exert cholesterol micelle-degrading activity in vitro

scientific article published on 7 June 2013

Pesthetoxin, a New Phytotoxin Produced by the Gray Blight Fungus, Pestalotiopsis theae ⬇️

scientific article published on 25 March 2005

Phosphatidylglucoside exists as a single molecular species with saturated fatty acyl chains in developing astroglial membranes.

scientific article published in July 2006

Plant-growth regulator, imidazole-4-carboxamide, produced by the fairy ring forming fungus Lepista sordida

scientific article published on September 2010

Proline-Mediated Enantioselective Construction of Tetrahydropyrans via a Domino Aldol/Acetalization Reaction

scientific article published on 01 March 2008

Pyrrolizilactone, a new pyrrolizidinone metabolite produced by a fungus.

scientific article published on 29 May 2013

RK-1355A and B, novel quinomycin derivatives isolated from a microbial metabolites fraction library based on NPPlot screening

scientific article published on 5 February 2014

Remarkable Effects of Terminal Groups and Solvents on Helical Folding of o-Phenylene Oligomers

scientific article published in 2012

Representation of molecular configurations by CAST coding method

scientific article published on 01 September 2001

Reveromycin A biosynthesis uses RevG and RevJ for stereospecific spiroacetal formation.

scientific article published on 5 June 2011

Reveromycin A, a new antibiotic which inhibits the mitogenic activity of epidermal growth factor ⬇️

scientific article published on 01 February 1991

Rubralactone, Rubralides A, B and C, and Rubramin Produced byPenicillium rubrum ⬇️

article published in 2007

Sesquiterpene O-naphthoquinones from the root bark of Ulmus davidiana

scientific article published on 01 September 1996

Structural and immunochemical characterization of a Neisseria gonorrhoeae epitope defined by a monoclonal antibody 2C7; the antibody recognizes a conserved epitope on specific lipo-oligosaccharides in spite of the presence of human carbohydrate epit

scientific article

Structural determination of montanacin D by total synthesis

scientific article published on 03 September 2008

Structural elucidation and synthesis of vialinin C, a new inhibitor of TNF-α production

scientific article published on 08 March 2014

Structural revision of kynapcin-12 by total synthesis, and inhibitory activities against prolyl oligopeptidase and cancer cells.

scientific article

Structural revision of terpenoids with a (3Z)-2-methyl-3-penten-2-ol moiety by the synthesis of (23E)- and (23Z)-cycloart-23-ene-3beta,25-diols

scientific article published on 17 May 2007

Structural revision of thelephantin G by total synthesis and the inhibitory activity against TNF-alpha production

scientific article

Structure of fomitellan A, a mannofucogalactan from the fruiting bodies of Fomitella fraxinea.

scientific article published on 12 November 2010

Study of 2-aminoquinolin-4(1H)-one under Mannich and retro-Mannich reaction

scientific article

Synthesis and biological activities of analogs of D-glucosyl-l-tyrosine, a humoral factor that stimulates transcription of the acyl-CoA binding protein in the pheromone gland of the Silkmoth, Bombyx mori.

scientific article published on 10 October 2006

Synthesis and biological activity of both enantiomers of kujigamberol isolated from 85-million-years-old Kuji amber

scientific article published on 15 May 2012

Synthesis and biological activity of ester and ether analogues of alpha-galactosylceramide (KRN7000).

scientific article published on 12 May 2010

Synthesis and biological activity of hydroxylated analogues of KRN7000 (α-galactosylceramide).

scientific article

Synthesis and structural revision of a brominated sesquiterpenoid, aldingenin C

scientific article published on 12 September 2014

Synthesis and structural revision of phomopsin B, a novel polyketide carrying a 10-membered cyclic-ether ring

scientific article published on 26 May 2011

Synthesis of 1alpha,25-dihydroxyvitamin D3-26,23-lactams (DLAMs), a novel series of 1 alpha,25-dihydroxyvitamin D3 antagonist.

scientific article published in May 2004

Synthesis of 6-oxy functionalized campest-4-en-3-ones: efficient hydroperoxidation at C-6 of campest-5-en-3-one with molecular oxygen and silica gel.

scientific article

Synthesis of All Stereoisomers of Monomeric Spectomycin A1/A2 and Evaluation of Their Protein SUMOylation-Inhibitory Activity

scientific article published on 20 May 2019

Synthesis of RCAI-172 (C6 epimer of RCAI-147) and its biological activity

scientific article published on 11 December 2013

Synthesis of atromentin and its O-alkylated natural products

scientific article

Synthesis of ovalicin starting from D-mannose.

scientific article

Synthesis of the Right-Side Structure of Type B Physalins

scientific article published on 9 November 2016

Synthetic studies on maitotoxin. 1. Stereoselective synthesis of the C'D'E'F'-ring system having a side chain

scientific article published on 08 April 2008

Synthetic studies on maitotoxin. 2. Stereoselective synthesis of the WXYZA'-ring system

scientific article published on 08 April 2008

Synthetic studies on maitotoxin. 3. Stereoselective synthesis of the BCDE-ring system

scientific article published on 08 April 2008

Synthetic substrates for an endoplasmic reticulum protein-folding sensor, UDP-glucose: glycoprotein glucosyltransferase

scientific article published on 01 December 2005

The bisabolane sesquiterpenoid endoperoxide, 3,6-epidioxy-1,10-bisaboladiene, isolated from Cacalia delphiniifolia inhibits the growth of human cancer cells and induces apoptosis.

scientific article published on 7 September 2008

The industrial anaerobe Clostridium acetobutylicum uses polyketides to regulate cellular differentiation.

scientific article

Total Synthesis of (−)-Decarbamoyloxysaxitoxin

Total Synthesis of Kehokorins A-E, Cytotoxic p-Terphenyls

scientific article

Total Synthesis of the Proposed Structure for Aromin and Its Structural Revision

scientific article

Total synthesis of (+)-batzelladine A and (-)-batzelladine D, and identification of their target protein.

scientific article

Total synthesis of batzelladine D

scientific article published on 01 August 2002

Total synthesis of crambescidin 359

scientific article published on 01 January 2002

Total synthesis of the proposed structure for pyragonicin

scientific article published on 01 June 2005

Transformation of a 1‐Zirconacyclopent‐3‐yne, a Five‐Membered Cycloalkyne, into a 1‐Zirconacyclopent‐3‐ene and Formal “1‐Zirconacyclopenta‐2,3‐dienes”

scientific article published on 01 January 2008

Trichothecene 3-O-acetyltransferase protects both the producing organism and transformed yeast from related mycotoxins. Cloning and characterization of Tri101.

scientific article published in January 1998

Ubiquitin-specific peptidase 5, a target molecule of vialinin A, is a key molecule of TNF-α production in RBL-2H3 cells.

scientific article

Ustalic acid as a toxin and related compounds from the mushroom Tricholoma ustale.

scientific article

Verrulactone C with an unprecedented dispiro skeleton, a new inhibitor of Staphylococcus aureus enoyl-ACP reductase, from Penicillium verruculosum F375.

scientific article published on 4 December 2013

Verrulactones D and E with unprecedented skeletons, new inhibitors of Staphylococcus aureus enoyl-ACP reductase, from Penicillium verruculosum F375

scientific article published on 26 August 2015

Vialinin A, a novel 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical scavenger from an edible mushroom in China. ⬇️

scientific article published in December 2005

Vialinin A, a novel potent inhibitor of TNF-alpha production from RBL-2H3 cells

scientific article

Vialinin B, a novel potent inhibitor of TNF-alpha production, isolated from an edible mushroom, Thelephora vialis.

scientific article published on 9 August 2006

Yeast Ca(2+)-signal transduction inhibitors isolated from Dominican amber prevent the degranulation of RBL-2H3 cells through the inhibition of Ca(2+)-influx

scientific article published on August 2016

[18]/[20]π Hemiporphyrazine: A Redox-Switchable Near-Infrared Dye

scientific article published on 21 December 2011

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