List of works - Didier Attaix

A dedication to Alfred L. Goldberg.

scientific article published in October 2013

A muscle-specific MuRF1-E2 network requires stabilization of MuRF1-E2 complexes by telethonin, a newly identified substrate.

scientific article published on 22 December 2017

A new method of purification of proteasome substrates reveals polyubiquitination of 20 S proteasome subunits.

scientific article published on 21 December 2006

Altered responses in skeletal muscle protein turnover during aging in anabolic and catabolic periods.

scientific article

Apoptosis in capillary endothelial cells in ageing skeletal muscle

scientific article

Assessment of in vivo protein synthesis in lamb tissues with [3H]valine flooding doses

scientific article published on 01 July 1986

Brief fasting decreases protein synthesis in the brain of adult rats ⬇️

scientific article published on August 1, 1991

Calcium and α-tocopherol suppress cured-meat promotion of chemically induced colon carcinogenesis in rats and reduce associated biomarkers in human volunteers.

scientific article published on 11 September 2013

Class III phosphoinositide 3-kinase--Beclin1 complex mediates the amino acid-dependent regulation of autophagy in C2C12 myotubes.

scientific article published on December 2003

Contribution of liver, skin and skeletal muscle to whole-body protein synthesis in the young lamb

scientific article published on 01 July 1988

Coordinate expression of the 19S regulatory complex and evidence for ubiquitin-dependent telethonin degradation in the unloaded soleus muscle

scientific article published on 15 May 2008

Curcumin treatment prevents increased proteasome and apoptosome activities in rat skeletal muscle during reloading and improves subsequent recovery.

scientific article

Deciphering the ubiquitin proteome: Limits and advantages of high throughput global affinity purification-mass spectrometry approaches.

scientific article published on 10 June 2013

Differential regulation of the lysosomal, Ca2+-dependent and ubiquitin/proteasome-dependent proteolytic pathways in fast-twitch and slow-twitch rat muscle following hyperinsulinaemia ⬇️

scientific article published on December 1, 2001

Docosahexaenoic acid-supplementation prior to fasting prevents muscle atrophy in mice

scientific article published on 15 February 2016

Down-regulation of genes in the lysosomal and ubiquitin-proteasome proteolytic pathways in calpain-3-deficient muscle.

scientific article published in May 2003

Effect of energy substrates on protein degradation in isolated small intestinal enterocytes from rats

scientific article published on 01 November 2006

Effects of alimentary whole proteins versus their small peptide hydrolysates on liver and skeletal muscle during the acute inflammation phase in the rat

scientific article published on 01 August 1998

Effects of ornithine alpha-ketoglutarate on protein metabolism in Yoshida sarcoma-bearing rats

scientific article published on 25 June 2007

Fasting does not increase mRNA levels of proteolytic systems in small intestinal mucosa of the rat.

scientific article published in October 2000

FoxO3 controls dangerous proteolytic liaisons

scientific article published on 01 December 2007

Glucocorticoids do not regulate the expression of proteolytic genes in skeletal muscle from Cushing's syndrome patients

scientific article published on 01 September 1997

Glucocorticoids regulate mRNA levels for subunits of the 19 S regulatory complex of the 26 S proteasome in fast-twitch skeletal muscles.

scientific article published on February 2004

Identification of cathepsin L as a differentially expressed message associated with skeletal muscle wasting

scientific article

Increased mRNA levels for components of the lysosomal, Ca2+-activated, and ATP-ubiquitin-dependent proteolytic pathways in skeletal muscle from head trauma patients.

scientific article published on April 1996

Insulin-like growth factor-1 and insulin resistance in skeletal muscles of adult and old rats

scientific article published on 01 March 1994

Lack of muscle recovery after immobilization in old rats does not result from a defect in normalization of the ubiquitin-proteasome and the caspase-dependent apoptotic pathways

scientific article published on 29 November 2010

Lower skeletal muscle capillarization in hypertensive elderly men.

scientific article published on 27 January 2016

Lysosomal and proteasome-dependent proteolysis are differentially regulated by insulin and/or amino acids following feeding in young, mature and old rats.

scientific article published on 11 September 2008

Lysosomal proteolysis in skeletal muscle

scientific article published on 23 March 2005

MAFbx/Atrogin-1 expression is a poor index of muscle proteolysis

article published in 2010

Mechanisms of skeletal muscle atrophy.

scientific article published on November 2006

Muscle wasting

scientific article published on 01 May 2012

Muscle wasting in a rat model of long-lasting sepsis results from the activation of lysosomal, Ca2+ -activated, and ubiquitin-proteasome proteolytic pathways.

scientific article published on April 1996

Muscle wasting: is mitochondrial dysfunction a key target?

scientific article published on 01 May 2015

Myostatin gene deletion prevents glucocorticoid-induced muscle atrophy

scientific article published on 12 October 2006

No alteration in gene expression of components of the ubiquitin-proteasome proteolytic pathway in dystrophin-deficient muscles

scientific article published on 01 September 1996

Pressure support ventilation attenuates ventilator-induced protein modifications in the diaphragm.

scientific article published on 11 September 2008

Protein synthesis and growth in the gastrointestinal tract of the young preruminant lamb

scientific article published on 01 July 1987

Proteolysis - A master regulator in health and disease

scientific article published on 2 September 2016

Proteomics of muscle chronological ageing in post-menopausal women

scientific article published on 23 December 2014

Recent progress in elucidating signalling proteolytic pathways in muscle wasting: potential clinical implications.

scientific article

Regulation of proteolysis during reloading of the unweighted soleus muscle

scientific article published on 01 May 2003

Regulation of skeletal muscle proteolysis by amino acids.

scientific article

Role of E2-Ub-conjugating enzymes during skeletal muscle atrophy

scientific article

Sensitivity and protein turnover response to glucocorticoids are different in skeletal muscle from adult and old rats. Lack of regulation of the ubiquitin-proteasome proteolytic pathway in aging ⬇️

scientific article published on November 1, 1995

Skeletal muscle lipid content and oxidative activity in relation to muscle fiber type in aging and metabolic syndrome.

scientific article

Skeletal muscle proteolysis in aging.

scientific article published on January 2009

Survival

scientific article published on 01 May 2012

The Missing Link: Mul1 Signals Mitophagy and Muscle Wasting ⬇️

scientific article published on 01 November 2012

The delayed recovery of the remobilized rat tibialis anterior muscle reflects a defect in proliferative and terminal differentiation that impairs early regenerative processes

scientific article published on 31 March 2015

The nutrition swing

scientific article

The role of adrenal hormones in the response of glutamine synthetase to fasting in adult and old rats ⬇️

scientific article published on December 1, 2003

The role of ubiquitin-proteasome-dependent proteolysis in the remodelling of skeletal muscle.

scientific article published in May 2004

The worsening of tibialis anterior muscle atrophy during recovery post-immobilization correlates with enhanced connective tissue area, proteolysis, and apoptosis.

scientific article

Too little or too much are inadequate

scientific article published on 01 May 2014

UBE2B is implicated in myofibrillar protein loss in catabolic C2C12 myotubes

scientific article published on 19 November 2015

UBE2D2 is not involved in MuRF1-dependent muscle wasting during hindlimb suspension

scientific article

USP19 is a ubiquitin-specific protease regulated in rat skeletal muscle during catabolic states

scientific journal article

Ubiquitin-proteasome-dependent muscle proteolysis responds slowly to insulin release and refeeding in starved rats.

scientific article

Ubiquitin-proteasome-dependent proteolytic activity remains elevated after zymosan-induced sepsis in rats while muscle mass recovers

scientific article published on 01 October 2005

Upregulation of MuRF1 and MAFbx participates to muscle wasting upon gentamicin-induced acute kidney injury.

scientific article

Whole-body and tissue protein synthesis during brief and prolonged fasting in the rat.

scientific article published in November 1991

List of works by Didier Attaix

A dedication to Alfred L. Goldberg.

A muscle-specific MuRF1-E2 network requires stabilization of MuRF1-E2 complexes by telethonin, a newly identified substrate.

A new method of purification of proteasome substrates reveals polyubiquitination of 20 S proteasome subunits.

Altered responses in skeletal muscle protein turnover during aging in anabolic and catabolic periods.

Apoptosis in capillary endothelial cells in ageing skeletal muscle

Assessment of in vivo protein synthesis in lamb tissues with [3H]valine flooding doses

Brief fasting decreases protein synthesis in the brain of adult rats ⬇️

Calcium and α-tocopherol suppress cured-meat promotion of chemically induced colon carcinogenesis in rats and reduce associated biomarkers in human volunteers.

Class III phosphoinositide 3-kinase--Beclin1 complex mediates the amino acid-dependent regulation of autophagy in C2C12 myotubes.

Contribution of liver, skin and skeletal muscle to whole-body protein synthesis in the young lamb

Coordinate expression of the 19S regulatory complex and evidence for ubiquitin-dependent telethonin degradation in the unloaded soleus muscle

Curcumin treatment prevents increased proteasome and apoptosome activities in rat skeletal muscle during reloading and improves subsequent recovery.

Deciphering the ubiquitin proteome: Limits and advantages of high throughput global affinity purification-mass spectrometry approaches.

Differential regulation of the lysosomal, Ca2+-dependent and ubiquitin/proteasome-dependent proteolytic pathways in fast-twitch and slow-twitch rat muscle following hyperinsulinaemia ⬇️

Docosahexaenoic acid-supplementation prior to fasting prevents muscle atrophy in mice

Down-regulation of genes in the lysosomal and ubiquitin-proteasome proteolytic pathways in calpain-3-deficient muscle.

Effect of energy substrates on protein degradation in isolated small intestinal enterocytes from rats

Effects of alimentary whole proteins versus their small peptide hydrolysates on liver and skeletal muscle during the acute inflammation phase in the rat

Effects of ornithine alpha-ketoglutarate on protein metabolism in Yoshida sarcoma-bearing rats

Fasting does not increase mRNA levels of proteolytic systems in small intestinal mucosa of the rat.

FoxO3 controls dangerous proteolytic liaisons

Glucocorticoids do not regulate the expression of proteolytic genes in skeletal muscle from Cushing's syndrome patients

Glucocorticoids regulate mRNA levels for subunits of the 19 S regulatory complex of the 26 S proteasome in fast-twitch skeletal muscles.

Identification of cathepsin L as a differentially expressed message associated with skeletal muscle wasting

Increased mRNA levels for components of the lysosomal, Ca2+-activated, and ATP-ubiquitin-dependent proteolytic pathways in skeletal muscle from head trauma patients.

Insulin-like growth factor-1 and insulin resistance in skeletal muscles of adult and old rats

Lack of muscle recovery after immobilization in old rats does not result from a defect in normalization of the ubiquitin-proteasome and the caspase-dependent apoptotic pathways

Lower skeletal muscle capillarization in hypertensive elderly men.

Lysosomal and proteasome-dependent proteolysis are differentially regulated by insulin and/or amino acids following feeding in young, mature and old rats.

Lysosomal proteolysis in skeletal muscle

MAFbx/Atrogin-1 expression is a poor index of muscle proteolysis

Mechanisms of skeletal muscle atrophy.

Muscle wasting

Muscle wasting in a rat model of long-lasting sepsis results from the activation of lysosomal, Ca2+ -activated, and ubiquitin-proteasome proteolytic pathways.

Muscle wasting: is mitochondrial dysfunction a key target?

Myostatin gene deletion prevents glucocorticoid-induced muscle atrophy

No alteration in gene expression of components of the ubiquitin-proteasome proteolytic pathway in dystrophin-deficient muscles

Pressure support ventilation attenuates ventilator-induced protein modifications in the diaphragm.

Protein synthesis and growth in the gastrointestinal tract of the young preruminant lamb

Proteolysis - A master regulator in health and disease

Proteomics of muscle chronological ageing in post-menopausal women

Recent progress in elucidating signalling proteolytic pathways in muscle wasting: potential clinical implications.

Regulation of proteolysis during reloading of the unweighted soleus muscle

Regulation of skeletal muscle proteolysis by amino acids.

Role of E2-Ub-conjugating enzymes during skeletal muscle atrophy

Sensitivity and protein turnover response to glucocorticoids are different in skeletal muscle from adult and old rats. Lack of regulation of the ubiquitin-proteasome proteolytic pathway in aging ⬇️

Skeletal muscle lipid content and oxidative activity in relation to muscle fiber type in aging and metabolic syndrome.

Skeletal muscle proteolysis in aging.

Survival

The Missing Link: Mul1 Signals Mitophagy and Muscle Wasting ⬇️

The delayed recovery of the remobilized rat tibialis anterior muscle reflects a defect in proliferative and terminal differentiation that impairs early regenerative processes

The nutrition swing

The role of adrenal hormones in the response of glutamine synthetase to fasting in adult and old rats ⬇️

The role of ubiquitin-proteasome-dependent proteolysis in the remodelling of skeletal muscle.

The worsening of tibialis anterior muscle atrophy during recovery post-immobilization correlates with enhanced connective tissue area, proteolysis, and apoptosis.

Too little or too much are inadequate

UBE2B is implicated in myofibrillar protein loss in catabolic C2C12 myotubes

UBE2D2 is not involved in MuRF1-dependent muscle wasting during hindlimb suspension

USP19 is a ubiquitin-specific protease regulated in rat skeletal muscle during catabolic states

Ubiquitin-proteasome-dependent muscle proteolysis responds slowly to insulin release and refeeding in starved rats.

Ubiquitin-proteasome-dependent proteolytic activity remains elevated after zymosan-induced sepsis in rats while muscle mass recovers

Upregulation of MuRF1 and MAFbx participates to muscle wasting upon gentamicin-induced acute kidney injury.

Whole-body and tissue protein synthesis during brief and prolonged fasting in the rat.

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