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List of works by Yoichi Takakusagi

13C-MR Spectroscopic Imaging with Hyperpolarized [1-13C]pyruvate Detects Early Response to Radiotherapy in SCC Tumors and HT-29 Tumors

scientific article published on 11 February 2015

A Strategy to Design Hyperpolarized 13 C Magnetic Resonance Probes Using [1-13 C]α-Amino Acid as a Scaffold Structure.

scientific article published on 22 March 2017

A screening of a library of T7 phage-displayed peptide identifies E2F-4 as an etoposide-binding protein.

scientific article (2011)

A sulfoglycolipid beta-sulfoquinovosyldiacylglycerol (betaSQDG) binds to Met1-Arg95 region of murine DNA polymerase lambda (Mmpol lambda) and inhibits its nuclear transit

scientific article

Camptothecin (CPT) directly binds to human heterogeneous nuclear ribonucleoprotein A1 (hnRNP A1) and inhibits the hnRNP A1/topoisomerase I interaction ⬇️

scientific article published on October 5, 2011

Camptothecin binds to a synthetic peptide identified by a T7 phage display screen

scientific article published in November 2005

Characterization of marine X-family DNA polymerases and comparative analysis of base excision repair proteins

scientific article published on 18 October 2011

Chemical properties of fatty acid derivatives as inhibitors of DNA polymerases.

scientific article published on 5 November 2007

Coenzyme Q10 as a potent compound that inhibits Cdt1-geminin interaction.

scientific article published on 21 September 2007

DNA polymerase mu interacts with a meiosis-specific RecA homolog Lim15 during meiosis in Coprinus cinereus.

scientific article

Design of a 15N Molecular Unit to Achieve Long Retention of Hyperpolarized Spin State

scientific article published on 9 January 2017

Design of a Hyperpolarized Molecular Probe for Detection of Aminopeptidase N Activity

scientific article published on 21 December 2015

Design of a hyperpolarized (15)N NMR probe that induces a large chemical-shift change upon binding of calcium ions.

scientific article published in August 2015

Design strategy for serine hydroxymethyltransferase probes based on retro-aldol-type reaction

scientific article published on 20 February 2019

Direct Monitoring of γ-Glutamyl Transpeptidase Activity In Vivo Using a Hyperpolarized (13) C-Labeled Molecular Probe

scientific article published on 2 August 2016

Effect of ionic interaction between a hyperpolarized magnetic resonance chemical probe and a gadolinium contrast agent for the hyperpolarized lifetime after dissolution.

scientific article published on 27 July 2016

Efficient one-cycle affinity selection of binding proteins or peptides specific for a small-molecule using a T7 phage display pool

scientific article

Foam fractionation of protein: correlation of protein adsorption onto bubbles with a pH-induced conformational transition

scientific article published on 18 August 2011

Heterogeneous nucleation of protein crystals on fluorinated layered silicate

scientific article

Identification and characterization of the direct interaction between methotrexate (MTX) and high-mobility group box 1 (HMGB1) protein.

scientific article

Identification of C10 biotinylated camptothecin (CPT-10-B) binding peptides using T7 phage display screen on a QCM device

scientific article

Identification of a methotrexate-binding peptide from a T7 phage display screen using a QCM device

scientific article

Identification of small molecule binding molecules by affinity purification using a specific ligand immobilized on PEGA resin

scientific article

Identification of trimannoside-recognizing peptide sequences from a T7 phage display screen using a QCM device

scientific article

In vivo imaging of tumor physiological, metabolic, and redox changes in response to the anti-angiogenic agent sunitinib: longitudinal assessment to identify transient vascular renormalization

scientific article

Lariatins, novel anti-mycobacterial peptides with a lasso structure, produced by Rhodococcus jostii K01-B0171

scientific article published on 01 June 2007

Phage display technology for target determination of small-molecule therapeutics: an update

scientific article published on 13 July 2020

Pyruvate induces transient tumor hypoxia by enhancing mitochondrial oxygen consumption and potentiates the anti-tumor effect of a hypoxia-activated prodrug TH-302.

scientific article

Ridaifen B, a tamoxifen derivative, directly binds to Grb10 interacting GYF protein 2.

scientific article published on 29 October 2012

Ridaifen G, tamoxifen analog, is a potent anticancer drug working through a combinatorial association with multiple cellular factors

scientific article

Screening of a library of T7 phage-displayed peptides identifies alphaC helix in 14-3-3 protein as a CBP501-binding site ⬇️

scientific article published on October 7, 2011

Synthesis of a biotinylated camptothecin derivative and determination of the binding sequence by T7 phage display technology

scientific article published in November 2005

The antitumor agent doxorubicin binds to Fanconi anemia group F protein ⬇️

scientific article published on September 16, 2012

Use of layer silicate for protein crystallization: effects of Micromica and chlorite powders in hanging drops

scientific article published on 06 November 2007

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