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List of works by Gabri van der Pluijm

ALK1Fc Suppresses the Human Prostate Cancer Growth in in Vitro and in Vivo Preclinical Models

scientific article published on 5 December 2017

Advances in optical imaging and novel model systems for cancer metastasis research.

scientific article published on 31 October 2007

BMP-7 inhibits TGF-β-induced invasion of breast cancer cells through inhibition of integrin β(3) expression.

scientific article

BMP7 activates brown adipose tissue and reduces diet-induced obesity only at subthermoneutrality

scientific article

BMP7, a putative regulator of epithelial homeostasis in the human prostate, is a potent inhibitor of prostate cancer bone metastasis in vivo

scientific article

Bisphosphonates inhibit stromelysin-1 (MMP-3), matrix metalloelastase (MMP-12), collagenase-3 (MMP-13) and enamelysin (MMP-20), but not urokinase-type plasminogen activator, and diminish invasion and migration of human malignant and endothelial cell

scientific article published in March 2002

Bone morphogenetic protein 7 in the development and treatment of bone metastases from breast cancer

scientific article

Bone morphogenetic protein 7 inhibits tumor growth of human uveal melanoma in vivo.

scientific article published on November 2007

Bone morphogenetic protein 7: a broad-spectrum growth factor with multiple target therapeutic potency

scientific article published on August 2011

Bone morphogenetic proteins and its receptors; therapeutic targets in cancer progression and bone metastasis?

scientific article published on January 2010

Breast cancer bone metastases: denosumab or zoledronic acid?

scientific article published on 01 March 2011

Celecoxib enhances doxorubicin-induced cytotoxicity in MDA-MB231 cells by NF-kappaB-mediated increase of intracellular doxorubicin accumulation.

scientific article published on 9 November 2006

Cell-based and molecular imaging tools for validating new therapies in the treatment of bone metabolic disorders and metastases

scientific article published on 01 December 2006

Combination of anti-angiogenic therapies reduces osteolysis and tumor burden in experimental breast cancer bone metastasis

scientific article published on 03 March 2014

Development of a Patient-Derived Xenograft (PDX) of Breast Cancer Bone Metastasis in a Zebrafish Model

scientific article published on 22 August 2016

Differential expression of TGFbeta-stimulated clone 22 in normal prostate and prostate cancer

scientific article published in February 2006

Dissociation of angiogenesis and osteoclastogenesis during endochondral bone formation in neonatal mice.

scientific article

Endothelial network formed with human dermal microvascular endothelial cells in autologous multicellular skin substitutes

scientific article

Epithelial Plasticity in Cancer: Unmasking a MicroRNA Network for TGF-β-, Notch-, and Wnt-Mediated EMT.

scientific article published on 25 March 2015

Epithelial plasticity, cancer stem cells and bone metastasis formation

scientific article published on 27 July 2010

Epithelial plasticity, cancer stem cells, and the tumor-supportive stroma in bladder carcinoma

scientific article published on 19 June 2012

Evaluation of the frequency of putative prostate cancer stem cells in primary and metastatic prostate cancer

scholarly article by Colby L. Eaton et al published 2010 in The Prostate

Functional imaging of multidrug resistance in an orthotopic model of osteosarcoma using 99mTc-sestamibi

scientific article published on June 2007

Glucocorticoid receptor antagonism reverts docetaxel resistance in human prostate cancer

scientific article published on 19 October 2015

Glycogen synthase kinase-3β inhibition depletes the population of prostate cancer stem/progenitor-like cells and attenuates metastatic growth.

scientific article

High aldehyde dehydrogenase activity identifies tumor-initiating and metastasis-initiating cells in human prostate cancer

scientific article

Improving Taxane-Based Chemotherapy in Castration-Resistant Prostate Cancer

scientific article published on 8 April 2016

In vitro and in vivo endochondral bone formation models allow identification of anti-angiogenic compounds

scientific article published on July 2003

Increased expression of putative cancer stem cell markers in primary prostate cancer is associated with progression of bone metastases.

scientific article

Inhibition of bone resorption and growth of breast cancer in the bone microenvironment

scientific article

Integrin αv expression is required for the acquisition of a metastatic stem/progenitor cell phenotype in human prostate cancer

scientific article

Interference with the microenvironmental support impairs the de novo formation of bone metastases in vivo

scientific article published on September 2005

Lack of noggin expression by cancer cells is a determinant of the osteoblast response in bone metastases

scientific article published on January 2007

Liposomal delivery of dexamethasone attenuates prostate cancer bone metastatic tumor growth in vivo.

scientific article published on 8 February 2015

Liposomal nanomedicines in the treatment of prostate cancer

scientific article published on 25 October 2013

Metastasis of prostate cancer and melanoma cells in a preclinical in vivo mouse model is enhanced by L-plastin expression and phosphorylation.

scientific article published on 18 January 2014

Multimodal imaging and treatment of bone metastasis.

scientific article published on 22 October 2008

Nuclear Eg5 (kinesin spindle protein) expression predicts docetaxel response and prostate cancer aggressiveness.

scientific article published on September 2014

Optical imaging of cancer metastasis to bone marrow: a mouse model of minimal residual disease

scientific article published on March 2002

Osteotropic cancers: from primary tumor to bone

scientific article published on 15 July 2008

Patient-derived tumour models for personalized therapeutics in urological cancers

scientific article published on 10 November 2020

Preclinical imaging of the cellular and molecular events in the multistep process of bone metastasis

scientific article published on April 2012

Preclinical models that illuminate the bone metastasis cascade

scientific article published on January 2012

Prostate cancer cells home to bone using a novel in vivo model: modulation by the integrin antagonist GLPG0187.

scientific article published on 4 September 2014

Radium-223 chloride: Extending life in prostate cancer patients by treating bone metastases.

scientific article

Real-time cancer cell tracking by bioluminescence in a preclinical model of human bladder cancer growth and metastasis

scientific article published on 19 May 2011

SYK is a candidate kinase target for the treatment of advanced prostate cancer.

scientific article

Spontaneous bone metastases in a preclinical orthotopic model of invasive lobular carcinoma; the effect of pharmacological targeting TGFβ receptor I kinase.

scientific article published on 23 January 2015

Spontaneous development of Epstein-Barr Virus associated human lymphomas in a prostate cancer xenograft program

scientific article published on 16 November 2017

Stem-like cells with luminal progenitor phenotype survive castration in human prostate cancer

scientific article

TGF-beta and BMP7 interactions in tumour progression and bone metastasis

scientific article

Targeting of alpha-v integrins reduces malignancy of bladder carcinoma

scientific article

Targeting of α(v)-integrins in stem/progenitor cells and supportive microenvironment impairs bone metastasis in human prostate cancer

scientific article

The TGF-β/Smad pathway induces breast cancer cell invasion through the up-regulation of matrix metalloproteinase 2 and 9 in a spheroid invasion model system

scientific article published on 5 September 2010

The aldehyde dehydrogenase enzyme 7A1 is functionally involved in prostate cancer bone metastasis.

scientific article published on 07 June 2011

The molecular signature of the stroma response in prostate cancer-induced osteoblastic bone metastasis highlights expansion of hematopoietic and prostate epithelial stem cell niches

scientific article

The role of microRNAs in bone metastasis

scientific article published on 8 July 2016

The tumor suppressor Smad4 is required for transforming growth factor beta-induced epithelial to mesenchymal transition and bone metastasis of breast cancer cells

scientific article published on February 2006

Transition of healthy to diseased synovial tissue in rheumatoid arthritis is associated with gain of mesenchymal/fibrotic characteristics

scientific article published on January 2006

Whole-body bioluminescent imaging of human uveal melanoma in a new mouse model of local tumor growth and metastasis

scientific article

Whole-body optical imaging in animal models to assess cancer development and progression

scientific article published on June 2007

XRP44X, an Inhibitor of Ras/Erk Activation of the Transcription Factor Elk3, Inhibits Tumour Growth and Metastasis in Mice

scientific article

miR-25 Modulates Invasiveness and Dissemination of Human Prostate Cancer Cells via Regulation of αv- and α6-Integrin Expression.

scientific article

miR-25, integrin and cancer invasiveness

scientific article published on 24 August 2015

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