Search filters

List of works by Karsten Maeder

A detailed analysis of biodegradable nanospheres by different techniques--a combined approach to detect particle sizes and size distributions

scientific article published on 26 December 2007

A new self-emulsifying drug delivery system (SEDDS) for poorly soluble drugs: characterization, dissolution, in vitro digestion and incorporation into solid pellets.

scientific article

A radical containing injectable in-situ-oleogel and emulgel for prolonged in-vivo oxygen measurements with CW EPR

scientific article published on 27 October 2018

Accumulation of nanocarriers in the ovary: a neglected toxicity risk?

scientific article

Acid-induced degradation of widely used NIR dye DiR causes hypsochromic shift in fluorescence properties

scientific article published on 21 February 2019

An in-depth examination of fatty acid solubility limits in biotherapeutic protein formulations containing polysorbate 20 and polysorbate 80

scientific article published on 12 October 2020

Analysis of the meal-dependent intragastric performance of a gastric-retentive tablet assessed by magnetic resonance imaging.

scientific article published in October 2003

Antioxidant capacity of bilberry extract microencapsulated in whey protein hydrogels

article published in 2012

Application of Benchtop-magnetic resonance imaging in a nude mouse tumor model.

scientific article

Application of atomic force microscopy and ultrasonic resonator technology on nanoscale: distinction of nanoemulsions from nanocapsules

scientific article

Application of electron paramagnetic resonance (EPR) spectroscopy and imaging in drug delivery research - chances and challenges.

scientific article published on 31 August 2009

Assessment of net charge and protein-protein interactions of different monoclonal antibodies

scientific article published on 03 February 2011

Benchtop MRI for pharmacokinetic evaluation of two aqueous-based nano-scaled formulations of oleic acid stabilized magnetite nanocrystals

scientific article

Benchtop-MRI for in vivo imaging using a macromolecular contrast agent based on hydroxyethyl starch (HES).

scientific article

Benchtop-NMR and MRI--a new analytical tool in drug delivery research

scientific article

Benchtop-magnetic resonance imaging (BT-MRI) characterization of push-pull osmotic controlled release systems

scientific article

Bioactivity of immobilized hyaluronic acid derivatives regarding protein adsorption and cell adhesion.

scientific article

Carbohydrate plasma expanders for passive tumor targeting: in vitro and in vivo studies

scientific article published on 15 March 2013

Characterization of PLGA nanospheres stabilized with amphiphilic polymers: hydrophobically modified hydroxyethyl starch vs pluronics

scientific article

Characterization of chitosan and its derivatives using asymmetrical flow field-flow-fractionation: a comparison with traditional methods

scientific article published on 17 August 2007

Characterization of poly(vinyl acetate) based floating matrix tablets

scientific article

Characterization of scaffolds for tissue engineering by benchtop-magnetic resonance imaging.

scientific article

Characterization of superparamagnetic iron oxide nanoparticles by asymmetrical flow-field-flow-fractionation

scientific article

Characterization of thermosensitive chitosan-based hydrogels by rheology and electron paramagnetic resonance spectroscopy

scientific article published on 12 July 2007

Characterizing molar mass distributions and molecule structures of different chitosans using asymmetrical flow field-flow fractionation combined with multi-angle light scattering.

scientific article

Combining R-DOTAP and a particulate antigen delivery platform to trigger dendritic cell activation: Formulation development and in-vitro interaction studies

scientific article published on 30 August 2017

Comparison of malondialdehyde and hydrogen peroxide modified CuZnSOD by EPR spectroscopy

scientific article published on 01 November 1993

Conjugation of Amine-Functionalized Polyesters With Dimethylcasein Using Microbial Transglutaminase

scientific article published on 02 November 2019

Controlled delivery of nanosuspensions from osmotic pumps: zero order and non-zero order kinetics.

scientific article

Controlled drug release to the inner ear: Concepts, materials, mechanisms, and performance

scientific article published on 09 March 2018

Controlled release dexamethasone implants in the round window niche for salvage treatment of idiopathic sudden sensorineural hearing loss

scientific article

Controlled release minocycline-lipid-complex extrudates for the therapy of periodontitis with enhanced flexibility

scientific article published on 29 June 2020

Core-shell structure of Miglyol/poly(D,L-lactide)/Poloxamer nanocapsules studied by small-angle neutron scattering

scientific article

Correlation between drug release kinetics from proteineous matrix and matrix structure: EPR and NMR study

scientific article published on 01 March 2000

Detection of free radicals in living mice after inhalation of DTBN by X-band ESR

scientific article published on 01 March 1993

Do in situ forming PLG/NMP implants behave similar in vitro and in vivo? A non-invasive and quantitative EPR investigation on the mechanisms of the implant formation process.

scientific article published on 17 June 2008

Does the commonly used pH-stat method with back titration really quantify the enzymatic digestibility of lipid drug delivery systems? A case study on solid lipid nanoparticles (SLN).

scientific article

Dual asymmetric centrifugation as an alternative preparation method for parenteral fat emulsions in preformulation development

scientific article

Dual dye in-vivo imaging of differentially charged PLGA carriers reveals antigen-depot effect, leading to improved immune responses in preclinical models

scientific article published on 2 February 2018

Dual fluorescent HPMA copolymers for passive tumor targeting with pH-sensitive drug release II: impact of release rate on biodistribution

scientific article published on 19 May 2013

Dual fluorescent HPMA copolymers for passive tumor targeting with pH-sensitive drug release: synthesis and characterization of distribution and tumor accumulation in mice by noninvasive multispectral optical imaging

scientific article published on 10 February 2012

ESR studies on the influence of physiological dissolution and digestion media on the lipid phase characteristics of SEDDS and SEDDS pellets.

scientific article

Electrospun Nimodipine-loaded fibers for nerve regeneration: development and in vitro performance

scientific article published on 10 April 2020

Electrospun nanofibers - A promising solid in-situ gelling alternative for ocular drug delivery

scientific article published on 07 December 2019

Enhanced optical imaging properties of lipid nanocapsules as vehicles for fluorescent conjugated polymers

scientific article published on 21 July 2020

Enzymatically catalyzed HES conjugation using microbial transglutaminase: Proof of feasibility.

scientific article

Enzymatically catalyzed conjugation of a biodegradable polymer to proteins and small molecules using microbial transglutaminase

scientific article published on 01 January 2011

Evaluating the Role of Solubility in Oral Absorption of Poorly Water-Soluble Drugs Using Physiologically-Based Pharmacokinetic Modeling

scientific article published on 21 November 2019

Evaluation of the immuno-stimulatory potential of stopper extractables and leachables by using dendritic cells as readout

scientific article published in October 2009

Extrudates of lipophilic tetracycline complexes: A new option for periodontitis therapy

scientific article published on 31 October 2019

Fabrication and characterization of a biomimetic composite scaffold for bone defect repair

scientific article published on 01 July 2010

Fluorescence optical imaging in anticancer drug delivery

scientific article published on 15 February 2016

Formation of structured polygonal nanoparticles by phase-separated comb-like polymers.

scientific article

Functionality of surface-coupled oxidised glycosaminoglycans towards fibroblast adhesion

Gamma-irradiation stability of saturated and unsaturated aliphatic polyanhydrides--ricinoleic acid based polymers.

scientific article published in January 2001

Gamma-sterilization-induced radicals in biodegradable drug delivery systems.

scientific article

Heavy metal contamination of nanosuspensions produced by high-pressure homogenisation

scientific article published on 01 March 2000

How changes in molecular weight and PDI of a polymer in amorphous solid dispersions impact dissolution performance

scientific article published on 13 December 2018

How do in-vitro release profiles of nanosuspensions from Alzet® pumps correspond to the in-vivo situation? A case study on radiolabeled fenofibrate.

scientific article

How stealthy are PEG-PLA nanoparticles? An NIR in vivo study combined with detailed size measurements.

scientific article

Hydrophobically modified hydroxyethyl starch: synthesis, characterization, and aqueous self-assembly into nano-sized polymeric micelles and vesicles

scientific article

Identification of solubility-limited absorption of oral anticancer drugs using PBPK modeling based on rat PK and its relevance to human

scientific article published on 17 June 2020

Imaging tools for pharmaceutical development

scientific article published on 15 November 2009

Impact of amorphization and GI physiology on supersaturation and precipitation of poorly soluble weakly basic drugs using a small-scale in vitro transfer model

scientific article published on 04 December 2019

Improved Tumor-Specific Drug Accumulation by Polymer Therapeutics with pH-Sensitive Drug Release Overcomes Chemotherapy Resistance

scientific article

Improved stability and cell response by intrinsic cross-linking of multilayers from collagen I and oxidized glycosaminoglycans

scientific article published on 7 October 2014

Improving the drug release of Naproxen Sodium tablets by preparing granules and tablets with a preferred mixing ratio of hydrates

scientific article published on 19 September 2017

In Vitro Evaluation of Antimicrobial Activity of Minocycline Formulations for Topical Application in Periodontal Therapy

scientific article published on 13 April 2020

In situ forming implants - an attractive formulation principle for parenteral depot formulations.

scientific article

In vitro toxicity of Stearoyl-poly(glycerol adipate) nanoparticles.

scientific article

In vitro-in vivo evaluation of nanosuspension release from subcutaneously implantable osmotic pumps.

scientific article

In vitro/in vivo comparison of drug release and polymer erosion from biodegradable P(FAD-SA) polyanhydrides--a noninvasive approach by the combined use of electron paramagnetic resonance spectroscopy and nuclear magnetic resonance imaging.

scientific article published on June 1997

In vivo EPR: an effective new tool for studying pathophysiology, physiology and pharmacology.

scientific article published on November 1996

In-situ forming composite implants for periodontitis treatment: How the formulation determines system performance

scientific article published on 16 March 2015

In-vivo monitoring of acute DSS-Colitis using Colonoscopy, high resolution Ultrasound and bench-top Magnetic Resonance Imaging in Mice.

scientific article

In-vivo studies on intraperitoneally administrated poly(vinyl alcohol).

scientific article

Indomethacin functionalised poly(glycerol adipate) nanospheres as promising candidates for modified drug release

scientific article published on 29 July 2018

Influence of different parameters on reconstitution of lyophilized SLN

scientific article published on 01 March 2000

Influence of drug treatment on the microacidity in rat and human skin--an in vitro electron spin resonance imaging study.

scientific article published in April 2001

Influence of high pressure homogenisation equipment on nanodispersions characteristics

scientific article published on 01 March 2000

Injectable LiNc-BuO loaded microspheres as in vivo EPR oxygen sensors after co-implantation with tumor cells

scientific article

Intended and Unintended Targeting of Polymeric Nanocarriers: The Case of Modified Poly(glycerol adipate) Nanoparticles.

scientific article

Interactions of nanoparticles with body proteins--improvement of 2D-PAGE-analysis by internal standard

scientific article published on 01 March 2000

Intracochlear PLGA based implants for dexamethasone release: Challenges and solutions

scientific article published on 21 May 2019

Intratumoral Distribution and pH-Dependent Drug Release of High Molecular Weight HPMA Copolymer Drug Conjugates Strongly Depend on Specific Tumor Substructure and Microenvironment

scientific article published on 21 August 2020

Investigation of the stabilizer elimination during the washing step of charged PLGA microparticles utilizing a novel HPLC-UV-ELSD method

scientific article published on 2 July 2015

Investigation on the viscoelastic properties of lipid based colloidal drug carriers

scientific article published on 01 March 2000

Investigations on the structure of solid lipid nanoparticles (SLN) and oil-loaded solid lipid nanoparticles by photon correlation spectroscopy, field-flow fractionation and transmission electron microscopy

scientific article published in March 2004

Isostatic ultra-high-pressure effects on supercooled melts in colloidal triglyceride dispersions

scientific article published on 22 September 2005

Liposomes as vehicles for water insoluble platinum-based potential drug: 2-(4-(tetrahydro-2H-pyran-2-yloxy)-undecyl)-propane-1,3-diamminedichloroplatinum(II).

scientific article

Loading and mobility of spin-labeled insulin in physiologically responsive complexation hydrogels intended for oral administration

scientific article

Magnetic resonance imaging for the in vivo evaluation of gastric-retentive tablets.

scientific article published in December 2003

Mechanistic analysis of PLGA/HPMC-based in-situ forming implants for periodontitis treatment

scientific article published on 03 June 2015

Mechanistic analysis of drug release from tablets with membrane controlled drug delivery

scientific article published on 28 September 2006

Melanoma-Derived Exosomal miR-125b-5p Educates Tumor Associated Macrophages (TAMs) by Targeting Lysosomal Acid Lipase A (LIPA)

scientific article published on 17 February 2020

Melt-based screening method with improved predictability regarding polymer selection for amorphous solid dispersions

scientific article published on 30 August 2018

Miniaturized Measurement of Drug-Polymer Interactions via Viscosity Increase for Polymer Selection in Amorphous Solid Dispersions

scientific article published on 12 April 2019

Moderate inappropriately high aldosterone/NaCl constellation in mice: cardiovascular effects and the role of cardiovascular epidermal growth factor receptor

scientific article

Modulating pH-independent release from coated pellets: effect of coating composition on solubilization processes and drug release

scientific article

Monitoring drug delivery processes by EPR and related techniques--principles and applications

scientific article

Monitoring microviscosity and microacidity of the albumin microenvironment inside degrading microparticles from poly(lactide-co-glycolide) (PLG) or ABA-triblock polymers containing hydrophobic poly(lactide-co-glycolide) A blocks and hydrophilic poly

scientific article published on May 1998

Monitoring of dissolution induced changes in film coat composition by 1H NMR spectroscopy and SEM.

scientific article

Monitoring of in vitro fat digestion by electron paramagnetic resonance spectroscopy.

scientific article

Monitoring of internal pH gradients within multi-layer tablets by optical methods and EPR imaging.

scientific article

Monitoring of xenograft tumor growth and response to chemotherapy by non-invasive in vivo multispectral fluorescence imaging.

scientific article

Multiple grafting to enzymatically synthesized polyesters

scientific article published on 29 May 2019

Nanoparticles with decreasing surface hydrophobicities: influence on plasma protein adsorption

scientific article published on 01 March 2000

Nanoscopic Characterization of Stearic Acid Release from Bovine Serum Albumin Hydrogels

scientific article published on 22 June 2020

New insight into modified release pellets - Internal structure and drug release mechanism.

scientific article

New insights on poly(vinyl acetate)-based coated floating tablets: characterisation of hydration and CO2 generation by benchtop MRI and its relation to drug release and floating strength.

scientific article

Nicardipine Loaded Solid Phospholipid Extrudates for the Prevention of Cerebral Vasospasms: In Vitro Characterization

scientific article published on 28 August 2020

Non-destructive and localized assessment of acidic microenvironments inside biodegradable polyanhydrides by spectral spatial electron paramagnetic resonance imaging

scholarly article by Karsten Maeder et al published January 1997 in Polymer

Non-invasive MRI detection of individual pellets in the human stomach.

scientific article published on 12 October 2009

Non-invasive in vivo characterization of microclimate pH inside in situ forming PLGA implants using multispectral fluorescence imaging

scientific article

Non-invasive in vivo evaluation of in situ forming PLGA implants by benchtop magnetic resonance imaging (BT-MRI) and EPR spectroscopy

scientific article published on 21 June 2009

Noninvasive characterization (EPR, μCT, NMR) of 3D PLA electrospun fiber sponges for controlled drug delivery

scientific article published on 27 August 2020

Noninvasive in vivo monitoring of the biofate of 195 kDa poly(vinyl alcohol) by multispectral fluorescence imaging

scientific article

Noninvasive measurement of the pH inside the gut by using pH-sensitive nitroxides. An in vivo EPR study

scientific article published on 01 November 1996

Novel aqueous nano-scaled formulations of oleic acid stabilized hydrophobic superparamagnetic iron oxide nanocrystals ⬇️

scientific article published on March 14, 2012

Novel mineralized heparin-gelatin nanoparticles for potential application in tissue engineering of bone

scientific article

Novel semisolid SNEDDS based on PEG-30-di-(polyhydroxystearate): Progesterone incorporation and in vitro digestion.

scientific article

Novel semisolid SNEDDS based on PEG-30-dipolyhydroxystearate: development and characterization.

scientific article

Oral Administration of Artemisone for the Treatment of Schistosomiasis: Formulation Challenges and In Vivo Efficacy

scientific article published on 03 June 2020

Ovarian Accumulation of Nanoemulsions: Impact of Mice Age and Particle Size ⬇️

journal article from 'International Journal of Molecular Sciences' published in 2021

PLGA nanoparticles for peroral delivery: How important is pancreatic digestion and can we control it?

scientific article

Passive Tumor Targeting of Polymer Therapeutics: In Vivo Imaging of Both the Polymer Carrier and the Enzymatically Cleavable Drug Model

scientific article published on 22 September 2016

Pharmaceutical applications of in vivo EPR.

scientific article published on July 1998

Pharmaceutical applications of magnetic resonance imaging (MRI).

scientific article

Phase inversion-based nanoemulsions of medium chain triglyceride as potential drug delivery system for parenteral applications

scientific article published on 17 January 2020

Phosphatidylserine (PS) and phosphatidylglycerol (PG) nanodispersions as potential anti-inflammatory therapeutics: Comparison of in vitro activity and impact of pegylation

scientific article published on 25 October 2019

Phosphatidylserine (PS)- and phosphatidylglycerol-(PG)-enriched mixed micelles (MM): a new nano-drug delivery system with anti-inflammatory potential?

scientific article published on 01 July 2020

Physico-chemical characterization of polysaccharide-coated nanoparticles

scientific article published on 19 September 2005

Physicochemical characterization of curcuminoid-loaded solid lipid nanoparticles

scientific article

Physicochemical investigations on solid lipid nanoparticles and on oil-loaded solid lipid nanoparticles: a nuclear magnetic resonance and electron spin resonance study.

scientific article

Physiological relevant in vitro evaluation of polymer coats for gastroretentive floating tablets.

scientific article

Poly (methyl vinyl ether-co-maleic acid) - Pectin Based Hydrogel-Forming Systems: Gel, Film, and Microneedles

scientific article

Poly(glycerol adipate) - indomethacin drug conjugates - synthesis and in vitro characterization

scientific article published on 23 August 2017

Poly(glycerol adipate)-fatty acid esters as versatile nanocarriers: From nanocubes over ellipsoids to nanospheres.

scientific article

Polymer degradation induced drug precipitation in PLGA implants - Why less is sometimes more

scientific article published on 19 March 2019

Preparation and Comparative Release Characteristics of Three Anthocyanin Encapsulation Systems

scientific article published on 13 January 2012

Preparation and characterization of a self-emulsifying pellet formulation

scientific article published on 29 November 2006

Preparation and characterization of biocompatible oil-loaded polyelectrolyte nanocapsules

article

Reduction of carcinogenic chromium(vi) on the skin of living rats ⬇️

scientific article published on October 1, 1997

Risperidone-Loaded PLGA-Lipid Particles with Improved Release Kinetics: Manufacturing and Detailed Characterization by Electron Microscopy and Nano-CT

scientific article published on 09 December 2019

Safety and robustness of coated pellets: self-healing film properties and storage stability.

scientific article published on 12 March 2009

Simultaneous controlled vitamin release from multiparticulates: Theory and experiment

scientific article published on 14 April 2011

Solid lipid nanoparticles (SLN) and oil-loaded SLN studied by spectrofluorometry and Raman spectroscopy.

scientific article published in November 2005

Solid lipid nanoparticles (SLN) based on binary mixtures of liquid and solid lipids: a (1)H-NMR study.

scientific article published in September 2000

Solid lipid nanoparticles (SLN) for controlled drug delivery - a review of the state of the art.

scientific article

Squalene containing solid lipid nanoparticles, a promising adjuvant system for yeast vaccines.

scientific article

Stabilization of indocyanine green by encapsulation within micellar systems.

scientific article

Structure and hydration properties of hydroxypropyl methylcellulose matrices containing naproxen and naproxen sodium.

scientific article

Sucrose ester nanodispersions: microviscosity and viscoelastic properties.

scientific article

Surface activity of a monoclonal antibody

scientific article published on 01 December 2009

Synthesis and EPR-spectroscopic characterization of the perchlorotriarylmethyl tricarboxylic acid radical (PTMTC) and its 13C labelled analogue (13C-PTMTC).

scientific article published on 17 February 2017

Synthesis of thiolated glycosaminoglycans and grafting to solid surfaces.

scientific article

Synthesis, Characterization, and Nanoencapsulation of Tetrathiatriarylmethyl and Tetrachlorotriarylmethyl (Trityl) Radical Derivatives—A Study To Advance Their Applicability as in Vivo EPR Oxygen Sensors.

scientific article

Tabotamp®, Respectively, Surgicel®, Increases the Cell Death of Neuronal and Glial Cells In Vitro

scientific article published on 28 May 2020

Tetracycline-HCl-loaded poly(DL-lactide-co-glycolide) microspheres prepared by a spray drying technique: influence of gamma-irradiation on radical formation and polymer degradation.

scientific article published in May 1999

The degradation, swelling and erosion properties of biodegradable implants prepared by extrusion or compression moulding of poly(lactide-co-glycolide) and ABA triblock copolymers

scientific article published on 01 May 2000

The influence of covalently linked and free polyethylene glycol on the structural and release properties of rhBMP-2 loaded microspheres.

scientific article

The motional dynamics in bolaamphiphilic nanofibers and micellar aggregates: an ESR spin probe study.

scientific article

Toward a detailed characterization of oil adsorbates as "solid liquids".

scientific article

Tracking the urinary excretion of high molar mass poly(vinyl alcohol).

scientific article

Tumor accumulation of NIR fluorescent PEG-PLA nanoparticles: impact of particle size and human xenograft tumor model

scientific article

Water dynamics in bolaamphiphile hydrogels investigated by 1H NMR relaxometry and diffusometry

scientific article

pH-sensitive imaging by low-frequency EPR: a model study for biological applications

scientific article published on 01 July 1998

Paulina is supported by:

About Paulina

Help