List of works - Patrick Lagüe

Aeromonas salmonicida Ati2 is an effector protein of the type three secretion system

scientific article published on 7 July 2013

Correction: tRNAGlu Increases the Affinity of Glutamyl-tRNA Synthetase for Its Inhibitor Glutamyl-Sulfamoyl-Adenosine, an Analogue of the Aminoacylation Reaction Intermediate Glutamyl-AMP: Mechanistic and Evolutionary Implications

scientific article published on 3 June 2015

Determining the mode of action involved in the antimicrobial activity of synthetic peptides: a solid-state NMR and FTIR study

scientific article published on 2 October 2012

Discovery of a sulfamate-based steroid sulfatase inhibitor with intrinsic selective estrogen receptor modulator properties

scientific article

Effect of Saturated Very Long-Chain Fatty Acids on the Organization of Lipid Membranes: A Study Combining (2)H NMR Spectroscopy and Molecular Dynamics Simulations

scientific article published on 28 June 2016

Efficient Restoration of the Dystrophin Gene Reading Frame and Protein Structure in DMD Myoblasts Using the CinDel Method.

scientific article

Extended linkers improve the detection of PPIs by DHFR PCA in living cells

scientific article published on 4 December 2017

Identification of fused 16β,17β-oxazinone-estradiol derivatives as a new family of non-estrogenic 17β-hydroxysteroid dehydrogenase type 1 inhibitors

scientific article

Impact of structural modifications at positions 13, 16 and 17 of 16β-(m-carbamoylbenzyl)-estradiol on 17β-hydroxysteroid dehydrogenase type 1 inhibition and estrogenic activity

scientific article published on 28 October 2015

Implementing a web-based introductory bioinformatics course for non-bioinformaticians that incorporates practical exercises

scientific article published on 13 September 2017

Insight into the mode of action and selectivity of PBRM, a covalent steroidal inhibitor of 17β-hydroxysteroid dehydrogenase type 1.

scientific article published on 8 August 2017

Ligand binding to truncated hemoglobin N from Mycobacterium tuberculosis is strongly modulated by the interplay between the distal heme pocket residues and internal water

scientific article published on 2 August 2008

Lipid-mediated interactions between intrinsic membrane proteins: dependence on protein size and lipid composition

scientific article

Mechanism of the Nitric Oxide Dioxygenase Reaction of Mycobacterium tuberculosis Hemoglobin N.

scientific article

Membrane Assembly and Ion Transport Ability of a Fluorinated Nanopore

scientific article

Molecular dynamics of class A β-lactamases-effects of substrate binding

scientific article published on 16 October 2012

Molecular dynamics simulations of the influenza hemagglutinin fusion peptide in micelles and bilayers: conformational analysis of peptide and lipids

scientific article

Peculiar inhibition of human mitochondrial aspartyl-tRNA synthetase by adenylate analogs

scientific article published on 28 February 2009

Peroxidase activity and involvement in the oxidative stress response of roseobacter denitrificans truncated hemoglobin

scientific article published on 6 February 2015

Quinazoline-4-piperidine sulfamides are specific inhibitors of human NPP1 and prevent pathological mineralization of valve interstitial cells

scientific article

Revisiting Peptide Amphiphilicity for Membrane Pore Formation ⬇️

scientific article published on 06 October 2011

Structural characterization of the tunnels of Mycobacterium tuberculosis truncated hemoglobin N from molecular dynamics simulations

scientific article

Structure and dynamics of Mycobacterium tuberculosis truncated hemoglobin N: insights from NMR spectroscopy and molecular dynamics simulations

scientific article

Synergistic applications of MD and NMR for the study of biological systems

scientific article

Synthesis and biological evaluation of novel quinazoline-4-piperidinesulfamide derivatives as inhibitors of NPP1.

scientific article published on 2 February 2018

Synthesis of novel substituted pyrimidine derivatives bearing a sulfamide group and their in vitro cancer growth inhibition activity

scientific article published on 19 November 2016

TEM-1 backbone dynamics-insights from combined molecular dynamics and nuclear magnetic resonance

scientific article published on February 2010

The I427T neuraminidase (NA) substitution, located outside the NA active site of an influenza A(H1N1)pdm09 variant with reduced susceptibility to NA inhibitors, alters NA properties and impairs viral fitness.

scientific article published on 9 November 2016

The influenza fusion peptide adopts a flexible flat V conformation in membranes

scientific article

The influenza fusion peptide promotes lipid polar head intrusion through hydrogen bonding with phosphates and N-terminal membrane insertion depth

scientific article published on 16 April 2014

Theoretical investigations of nitric oxide channeling in Mycobacterium tuberculosis truncated hemoglobin N.

scientific article published on December 2009

tRNAGlu increases the affinity of glutamyl-tRNA synthetase for its inhibitor glutamyl-sulfamoyl-adenosine, an analogue of the aminoacylation reaction intermediate glutamyl-AMP: mechanistic and evolutionary implications

scientific article published on 10 April 2015

List of works by Patrick Lagüe

Aeromonas salmonicida Ati2 is an effector protein of the type three secretion system

Correction: tRNAGlu Increases the Affinity of Glutamyl-tRNA Synthetase for Its Inhibitor Glutamyl-Sulfamoyl-Adenosine, an Analogue of the Aminoacylation Reaction Intermediate Glutamyl-AMP: Mechanistic and Evolutionary Implications

Determining the mode of action involved in the antimicrobial activity of synthetic peptides: a solid-state NMR and FTIR study

Discovery of a sulfamate-based steroid sulfatase inhibitor with intrinsic selective estrogen receptor modulator properties

Effect of Saturated Very Long-Chain Fatty Acids on the Organization of Lipid Membranes: A Study Combining (2)H NMR Spectroscopy and Molecular Dynamics Simulations

Efficient Restoration of the Dystrophin Gene Reading Frame and Protein Structure in DMD Myoblasts Using the CinDel Method.

Extended linkers improve the detection of PPIs by DHFR PCA in living cells

Identification of fused 16β,17β-oxazinone-estradiol derivatives as a new family of non-estrogenic 17β-hydroxysteroid dehydrogenase type 1 inhibitors

Impact of structural modifications at positions 13, 16 and 17 of 16β-(m-carbamoylbenzyl)-estradiol on 17β-hydroxysteroid dehydrogenase type 1 inhibition and estrogenic activity

Implementing a web-based introductory bioinformatics course for non-bioinformaticians that incorporates practical exercises

Insight into the mode of action and selectivity of PBRM, a covalent steroidal inhibitor of 17β-hydroxysteroid dehydrogenase type 1.

Ligand binding to truncated hemoglobin N from Mycobacterium tuberculosis is strongly modulated by the interplay between the distal heme pocket residues and internal water

Lipid-mediated interactions between intrinsic membrane proteins: dependence on protein size and lipid composition

Mechanism of the Nitric Oxide Dioxygenase Reaction of Mycobacterium tuberculosis Hemoglobin N.

Membrane Assembly and Ion Transport Ability of a Fluorinated Nanopore

Molecular dynamics of class A β-lactamases-effects of substrate binding

Molecular dynamics simulations of the influenza hemagglutinin fusion peptide in micelles and bilayers: conformational analysis of peptide and lipids

Peculiar inhibition of human mitochondrial aspartyl-tRNA synthetase by adenylate analogs

Peroxidase activity and involvement in the oxidative stress response of roseobacter denitrificans truncated hemoglobin

Quinazoline-4-piperidine sulfamides are specific inhibitors of human NPP1 and prevent pathological mineralization of valve interstitial cells

Revisiting Peptide Amphiphilicity for Membrane Pore Formation ⬇️

Structural characterization of the tunnels of Mycobacterium tuberculosis truncated hemoglobin N from molecular dynamics simulations

Structure and dynamics of Mycobacterium tuberculosis truncated hemoglobin N: insights from NMR spectroscopy and molecular dynamics simulations

Synergistic applications of MD and NMR for the study of biological systems

Synthesis and biological evaluation of novel quinazoline-4-piperidinesulfamide derivatives as inhibitors of NPP1.

Synthesis of novel substituted pyrimidine derivatives bearing a sulfamide group and their in vitro cancer growth inhibition activity

TEM-1 backbone dynamics-insights from combined molecular dynamics and nuclear magnetic resonance

The I427T neuraminidase (NA) substitution, located outside the NA active site of an influenza A(H1N1)pdm09 variant with reduced susceptibility to NA inhibitors, alters NA properties and impairs viral fitness.

The influenza fusion peptide adopts a flexible flat V conformation in membranes

The influenza fusion peptide promotes lipid polar head intrusion through hydrogen bonding with phosphates and N-terminal membrane insertion depth

Theoretical investigations of nitric oxide channeling in Mycobacterium tuberculosis truncated hemoglobin N.

tRNAGlu increases the affinity of glutamyl-tRNA synthetase for its inhibitor glutamyl-sulfamoyl-adenosine, an analogue of the aminoacylation reaction intermediate glutamyl-AMP: mechanistic and evolutionary implications