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List of works by Paul E. Marik

"Vitamin S" (Steroids) and Vitamin C for the Treatment of Severe Sepsis and Septic Shock!

scientific article

A 53-year-old man with fever, clubbing, hemoptysis, and rapid onset of respiratory failure.

scientific article

A 56-year-old man with multiple airway procedures with fever, cough, and dyspnea

scientific article published on December 2008

A 64-year-old male with fever and persistent lung infiltrate.

scientific article published on September 2009

Accelerated hyaluronan concentration as the primary driver of morbidity and mortality in high-risk COVID-19 patients: with therapeutic introduction of an oral hyaluronan inhibitor in the prevention of "Induced Hyaluronan Storm" Syndrome

scientific article published on 24 April 2020

Accuracy of bedside capillary blood glucose measurements in critically ill patients

scientific article published in September 2007

Activation and regulation of systemic inflammation in ARDS: rationale for prolonged glucocorticoid therapy

scientific article published on 03 October 2009

Acupuncture for Asthma

article

Acute ischemic stroke in the ICU: to admit or not to admit?

scientific article published on 8 April 2014

Acute unilateral pneumonitis in a patient with polymyositis: a unique presentation of polymyositis-associated pneumonitis.

scientific article published in December 2007

Adjuvant Vitamin C in critically ill patients undergoing renal replacement therapy: What's the right dose?

Adrenal insufficiency during septic shock

scientific article

Adrenal insufficiency in critically ill patients with human immunodeficiency virus

scientific article

Adrenal insufficiency in the critically ill: a new look at an old problem

scientific article

Adrenal-exhaustion syndrome in patients with liver disease

scientific article

Aliens, anaerobes, and the lung!

scientific article published on 01 July 2003

Aminoglycoside volume of distribution and illness severity in critically ill septic patients

scientific article published on 01 April 1993

An 18-year-old woman with fever, diffuse pulmonary opacities, and rapid onset of respiratory failure: idiopathic acute eosinophilic pneumonia.

scientific article published on December 2006

Anemia, allogenic blood transfusion, and immunomodulation in the critically ill.

scientific article

Arginine: mediator or modulator of sepsis?

scientific article

Association between time of admission to the ICU and mortality: a systematic review and metaanalysis

scientific article published on 23 April 2010

Authors' response

Automatic external defibrillators: lessons from the past, present and future.

scientific article

Bench-to-bedside review: Rhabdomyolysis -- an overview for clinicians

scientific article published in April 2005

Better ventilator settings using a computerized clinical tool

scientific article published on August 2014

Carbon monoxide poisoning and gas powered equipment

scientific article published on 01 October 2001

Carbon monoxide poisoning: a review for clinicians.

scientific article

Cardiopulmonary resuscitation in patients with cancer.

scientific article published on June 2007

Cardiopulmonary resuscitation: a review for clinicians

scientific article published on February 1998

Cardiovascular dysfunction of sepsis: a nitric oxide- and l-arginine-deficient state?

scientific article published in March 2003

Certification and training in critical care ultrasound

scientific article published on 09 November 2007

Characteristics of Patients With the “Malignant Obesity Hypoventilation Syndrome” Admitted to an ICU ⬇️

scientific article published on May 6, 2012

Chronic acetaminophen ingestion resulting in severe anion gap metabolic acidosis secondary to 5-oxoproline accumulation: an under diagnosed phenomenon

scientific article

Clinical and Scientific Rationale for the "MATH+" Hospital Treatment Protocol for COVID-19

scientific article published on 15 December 2020

Clinical information systems and the electronic medical record in the intensive care unit.

scientific article

Clinical review: the management of hypertensive crises

scientific article published on 16 July 2003

Comparing Changes in Carotid Flow Time and Stroke Volume Induced by Passive Leg Raising

scientific article published on 20 September 2017

Complete neurological recovery following delayed initiation of hypothermia in a victim of warm water near-drowning

scientific article published on 2 February 2006

Continuous venovenous hemodiafiltration in severe metabolic acidosis secondary to ethylene glycol ingestion

scientific article published in August 2010

Controversies and Misconceptions in Intensive Care Unit Nutrition

scientific article published on 09 July 2015

Correction to: Guidelines for the diagnosis and management of critical illness-related corticosteroid insufficiency (CIRCI) in critically ill patients (Part I): Society of Critical Care Medicine (SCCM) and European Society of Intensive Care Medicine

scientific article published on 23 February 2018

Corticosteroids in ARDS

scientific article published on 01 July 2006

Corticosteroids in ARDS: a counterpoint

scientific article published on 01 September 2007

Critical Illness-Related Corticosteroid Insufficiency (CIRCI): A Narrative Review from a Multispecialty Task Force of the Society of Critical Care Medicine (SCCM) and the European Society of Intensive Care Medicine (ESICM).

scientific article published on 21 September 2017

Critical illness-related corticosteroid insufficiency (CIRCI): a narrative review from a Multispecialty Task Force of the Society of Critical Care Medicine (SCCM) and the European Society of Intensive Care Medicine (ESICM).

scientific article

Customization of an Open-Lung Ventilation Strategy to Treat a Case of Life-Threatening Acute Respiratory Distress Syndrome ⬇️

scientific article published on January 21, 2011

Death by parenteral nutrition

scientific article published on 01 June 2003

Delirium in the ICU: an overview ⬇️

scientific article published on December 27, 2012

Developing Research Programs in Clinical and Translational Nutrition ⬇️

scientific article published on November 1, 2010

Do dietary supplements have beneficial health effects in industrialized nations: what is the evidence?

scientific article published on 24 January 2012

Doctor-your septic patients have scurvy!

scientific article published on 29 January 2018

Does central venous pressure predict fluid responsiveness? A systematic review of the literature and the tale of seven mares

scientific article published on July 2008

Does the Central Venous Pressure Predict Fluid Responsiveness? An Updated Meta-Analysis and a Plea for Some Common Sense* ⬇️

scientific article published on July 1, 2013

Don't miss the diagnosis of sepsis!

scientific article

Dopamine increases mortality in pediatric septic shock

scientific article

Dynamic changes in arterial waveform derived variables and fluid responsiveness in mechanically ventilated patients: a systematic review of the literature

scientific article published on September 2009

Early enteral nutrition in acutely ill patients: a systematic review.

scientific article

Early goal-directed therapy: on terminal life support?

scientific article

Early norepinephrine decreases fluid and ventilatory requirements in pediatric vasodilatory septic shock

scientific article published on October 2016

Elevated serum levels of the type I and type II receptors for tumor necrosis factor-alpha as predictive factors for ARF in patients with septic shock

scientific article

Etomidate and propylene glycol toxicity

scientific article published in May 1998

Fatal massive hemoptysis in a patient on low-dose oral prednisone: chronic necrotizing pulmonary aspergillosis.

scientific article published in January 2007

Feeding critically ill patients the right 'whey': thinking outside of the box. A personal view

scientific article published on 28 May 2015

Feeding the Critically Ill: More Questions Than Answers!

scientific article published in March 2017

Feeding the hemodynamically unstable patient: a critical evaluation of the evidence

scientific article published on 01 August 2003

Fluid administration in severe sepsis and septic shock, patterns and outcomes: an analysis of a large national database

scientific article published on 27 January 2017

Fluid management decisions should not be guided by fixed central venous pressure targets

scientific article

Fluid overload, de-resuscitation, and outcomes in critically ill or injured patients: a systematic review with suggestions for clinical practice

scientific article

French Intensive Care Society, International congress - Réanimation 2016

scientific article published in June 2016

Gastric versus post-pyloric feeding: a systematic review

scientific article

Glucocorticoid Treatment in Acute Lung Injury and Acute Respiratory Distress Syndrome ⬇️

scientific article published on July 1, 2011

Glucocorticoids in sepsis: dissecting facts from fiction

scientific article published on 06 May 2011

Guidelines for the Appropriate Use of Bedside General and Cardiac Ultrasonography in the Evaluation of Critically Ill Patients-Part I: General Ultrasonography

scientific article

Guidelines for the Appropriate Use of Bedside General and Cardiac Ultrasonography in the Evaluation of Critically Ill Patients-Part II: Cardiac Ultrasonography

scientific article published on June 2016

Guidelines for the Diagnosis and Management of Critical Illness-Related Corticosteroid Insufficiency (CIRCI) in Critically Ill Patients (Part I): Society of Critical Care Medicine (SCCM) and European Society of Intensive Care Medicine (ESICM) 2017.

scientific article published on 21 September 2017

Guidelines for the diagnosis and management of critical illness-related corticosteroid insufficiency (CIRCI) in critically ill patients (Part I): Society of Critical Care Medicine (SCCM) and European Society of Intensive Care Medicine (ESICM) 2017.

scientific article

Hearts in the Air

article

Hemodynamic parameters to guide fluid therapy ⬇️

scientific article published on March 21, 2011

Hydrocortisone and Ascorbic Acid Synergistically Prevent and Repair Lipopolysaccharide-Induced Pulmonary Endothelial Barrier Dysfunction

scientific article

Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study

scientific article

Hypertensive Crises

scientific article

Hypothalamic-pituitary-adrenal insufficiency

scientific article

Hypothermia and cytokines in septic shock. Norasept II Study Investigators. North American study of the safety and efficacy of murine monoclonal antibody to tumor necrosis factor for the treatment of septic shock

scientific article published on June 2000

IV 2beta or not 2beta, that is the question!

scientific article published in October 2002

Iatrogenic salt water drowning and the hazards of a high central venous pressure

scientific article

Immunonutrition in critically ill patients: a systematic review and analysis of the literature

scientific article published on 15 July 2008

Immunonutrition in high-risk surgical patients: a systematic review and analysis of the literature

scientific article published on July 2010

Inferior Vena Cava Variation Compared to Pulse Contour Analysis as Predictors of Fluid Responsiveness: A Prospective Cohort Study ⬇️

scientific article published on March 1, 2011

Inhaled Nitric Oxide as Salvage Therapy in Massive Pulmonary Embolism: A Case Series ⬇️

scientific article published on October 12, 2011

Intensive insulin therapy in the ICU: is it now time to jump off the bandwagon?

scientific article published on 23 March 2007

Is intravenous vitamin C contraindicated in patients with G6PD deficiency?

Is the band count useful in the diagnosis of infection? An accuracy study in critically ill patients

scientific article published on 13 September 2010

Lipid modulation and systemic inflammation

scientific article

Low-dose dopamine does not prevent acute renal failure in patients with septic shock and oliguria. NORASEPT II Study Investigators

scientific article published on 01 October 1999

Management of head trauma.

scientific article

Management of increased intracranial pressure: a review for clinicians.

scientific article

Management of patients with metastatic malignancy in the intensive care unit

scientific article published on December 2006

Management of sepsis during the early "golden hours".

scientific article published on August 2006

Meta-analysis of parenteral nutrition versus enteral nutrition in patients with acute pancreatitis

scientific article

Missing the (Acu) Point ⬇️

scientific article published on 01 April 2003

Monitoring therapeutic interventions in critically ill septic patients

scientific article published on 01 October 2004

Multidisciplinary family meetings in the ICU facilitate end-of-life decision making

scientific article

Narrative review: the management of acute decompensated heart failure

scientific article published on 26 May 2011

Natriuretic peptides in acute pulmonary embolism: a systematic review

scientific article published on 15 July 2008

Noninvasive hemodynamic monitoring in the intensive care unit

scientific article published on July 2007

Norepinephrine or dopamine for septic shock: systematic review of randomized clinical trials

scientific article

Normocaloric versus hypocaloric feeding in ICU patients: response to comments by Bitzani

scientific article

Normocaloric versus hypocaloric feeding on the outcomes of ICU patients: a systematic review and meta-analysis

scientific article

Not all propofol is created equal

scientific article published in February 2001

Obituary: pulmonary artery catheter 1970 to 2013

scientific article

One good turn deserves another!

scientific article published in September 2002

Oral vs Inhaled Corticosteroids Following Emergency Department Discharge of Patients With Acute Asthma

scientific article published on 01 June 2002

Parenteral versus enteral nutrition in the critically ill patient: a re-analysis of a flawed meta-analysis ⬇️

scientific article published on February 14, 2013

Passive leg raising for predicting fluid responsiveness: a systematic review and meta-analysis

scientific article published on 29 January 2016

Perioperative hypertension management

scientific article

Perioperative hypertension: a review of current and emerging therapeutic agents

scientific article published on May 2009

Physicians’ own preferences to the limitation and withdrawal of life-sustaining therapy

article

Prediction of fluid responsiveness: an update

scientific article

Procalcitonin is an essential biomarker for hydrocortisone, ascorbic acid, and thiamine (HAT) therapy in patients with sepsis

Prognostic value of cortisol response in septic shock

scientific article published on 01 July 2000

Prolonged and profound therapeutic hypothermia for the treatment of "brain death" after a suicidal intoxication. Challenging conventional wisdoms

scientific article published in February 2010

Prolonged glucocorticoid treatment is associated with improved ARDS outcomes: analysis of individual patients' data from four randomized trials and trial-level meta-analysis of the updated literature

scientific article published on 27 October 2015

Promoting enteral feeding 101

scientific article published on 01 July 2002

Protocols for the obvious: Where does it start, and stop?

scientific article published on 14 April 2017

Pulmonary complications of novel antineoplastic agents for solid tumors

scientific article

Pulmonary manifestations of peripheral T-cell lymphoma: case report and review of the literature

scientific article published in December 2007

Re-thinking resuscitation goals: an alternative point of view!

scientific article published on 8 October 2013

Recommendations for the diagnosis and management of corticosteroid insufficiency in critically ill adult patients: consensus statements from an international task force by the American College of Critical Care Medicine

scientific article

Refeeding hypophosphatemia in critically ill patients in an intensive care unit. A prospective study

scientific article

Requirement of perioperative stress doses of corticosteroids: a systematic review of the literature

scientific article published on December 2008

Restrictive Diseases

Review of the Emerging Evidence Demonstrating the Efficacy of Ivermectin in the Prophylaxis and Treatment of COVID-19

scholarly article

Sepsis-associated hyperlactatemia

scientific article

Sepsis: Current Definition, Pathophysiology, Diagnosis, and Management

scientific article

Should a cancer patient be resuscitated following an in-hospital cardiac arrest?

scientific article published in March 1998

Should age limit admission to the intensive care unit?

scientific article published on February 2007

Should family members be present during cardiopulmonary resuscitation? A review of the literature

scientific article published on August 2007

Steroid treatment in ARDS: a critical appraisal of the ARDS network trial and the recent literature

scientific article

Steroids in Acute Exacerbation of Asthma

scientific article published on 01 August 1999

Steroids in cardiac arrest: not ready for prime time?

scientific article published on 01 March 2007

Stress hyperglycemia: an essential survival response!

scientific article published on 06 March 2013

Stress hyperglycemia: an essential survival response!

scientific article published in June 2013

Stress hyperlactataemia: present understanding and controversy

scientific article

Stress ulcer prophylaxis in the new millennium: a systematic review and meta-analysis

scientific article

Stress-hyperglycemia, insulin and immunomodulation in sepsis

scientific article published on 26 February 2004

Sublingual capnometry versus traditional markers of tissue oxygenation in critically ill patients

scientific article published in March 2003

Sulfite-induced propofol oxidation: a cause for radical concern

scientific article published in March 2003

Surviving Sepsis Guidelines and Scientific Evidence? ⬇️

scientific article published on May 1, 2011

Surviving sepsis

scientific article published in October 2013

Surviving sepsis: going beyond the guidelines ⬇️

scientific article published on June 7, 2011

Techniques for assessment of intravascular volume in critically ill patients

scientific article published on September 2009

The Management of Sepsis: A Practical Review

article

The SEP-1 quality mandate may be harmful: How to drown a patient with 30 mL per kg fluid!

scientific article published on 18 November 2017

The adrenal-vitamin C axis: from fish to guinea pigs and primates

scholarly article

The central nervous system hypothalamic-pituitary-adrenal axis in sepsis

scientific article published in February 2002

The clinical features of severe community-acquired pneumonia presenting as septic shock. Norasept II Study Investigators

scientific article published on 01 September 2000

The definition of septic shock: implications for treatment.

scientific article published on March 2007

The demise of early goal-directed therapy for severe sepsis and septic shock

scientific article published on 06 February 2015

The dose makes the poison

scientific article

The effect of aging on circulating levels of proinflammatory cytokines during septic shock. Norasept II Study Investigators

scientific article published in January 2001

The emergent malignant obesity hypoventilation syndrome: a new critical care syndrome. Author reply

scientific article published in May 2013

The ex vivo antimicrobial activity and colonization rate of two antimicrobial-bonded central venous catheters

article

The hospital-survival and prognostic factors of patients with solid tumors admitted to an ICU.

scientific article published on 06 June 2008

The intensive care medicine research agenda in nutrition and metabolism

scientific article published on 03 April 2017

The management of acute severe asthma.

scientific article

The management of status epilepticus

scientific article

The optimal endpoint of resuscitation in trauma patients

scientific article

The risk of catheter-related bloodstream infection with femoral venous catheters as compared to subclavian and internal jugular venous catheters: a systematic review of the literature and meta-analysis

scientific article published on August 2012

The role of anaerobes in patients with ventilator-associated pneumonia and aspiration pneumonia: a prospective study

scientific article published on 01 January 1999

The role of head computer tomographic scans on the management of MICU patients with neurological dysfunction

scientific article published on 29 October 2009

The systolic blood pressure variation as an indicator of pulmonary capillary wedge pressure in ventilated patients

scientific article published on 01 August 1993

The time to offer treatments for COVID-19

scientific article

Therapeutic hypothermia: a state-of-the-art emergency medicine perspective

scientific article published on 12 May 2011

Therapeutic sedation: has its time come?

scientific article

Therapy of intracranial hypertension in patients with fulminant hepatic failure

scientific article

Thrombolytic therapy in a patient with suspected pulmonary embolism despite a negative computed tomography pulmonary angiogram ⬇️

scientific article published on January 21, 2011

Tight glycemic control in acutely ill patients: low evidence of benefit, high evidence of harm!

scientific article

Toward understanding tight glycemic control in the ICU: a systematic review and metaanalysis

scientific article published on 16 December 2009

Treatment of cardiac arrest with automatic external defibrillators: impact on outcome

scientific article published on January 2003

Treatment thresholds for hyperglycemia in critically ill patients with and without diabetes

scientific article

Using corticosteroids in intensive care

scientific article published in September 2006

Ventilator-Associated Pneumonia

scientific article published on 01 September 2001

What intensivists need to know about hemophagocytic syndrome: an underrecognized cause of death in adult intensive care units

scientific article published on 21 January 2011

What's new with hypertensive crises?

scientific article published on 19 November 2014

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