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List of works by Qihai Gong

A new hope for neurodegeneration: possible role of hydrogen sulfide.

scientific article published on January 2011

A novel compound derived from danshensu inhibits apoptosis via upregulation of heme oxygenase-1 expression in SH-SY5Y cells.

scientific article published on 14 January 2013

Alkaloids enriched extract from Dendrobium nobile Lindl. attenuates tau protein hyperphosphorylation and apoptosis induced by lipopolysaccharide in rat brain.

scientific article published on 20 November 2013

Antiapoptotic Effect of Novel Compound from Herba leonuri-Leonurine (SCM-198): A Mechanism Through Inhibition of Mitochondria Dysfunction in H9c2 Cells ⬇️

scientific article published on December 1, 2010

Association of serum chemerin and inflammatory factors with type 2 diabetes macroangiopathy and waist-to-stature ratio

scientific article published on 08 November 2019

CZ2HF mitigates β-amyloid 25-35 fragment-induced learning and memory impairment through inhibition of neuroinflammation and apoptosis in rats

scientific article published on 24 October 2018

CZYH Alleviates β-Amyloid-Induced Cognitive Impairment and Inflammation Response via Modulation of JNK and NF-κB Pathway in Rats

scientific article published on 04 November 2019

Can Aidi injection improve overall survival in patients with non-small cell lung cancer? A systematic review and meta-analysis of 25 randomized controlled trials.

scientific article published on 31 January 2018

Clinical Efficacy and Safety of Aidi Injection Plus Docetaxel-Based Chemotherapy in Advanced Nonsmall Cell Lung Cancer: A Meta-Analysis of 36 Randomized Controlled Trials.

scientific article published on 11 June 2018

Clinical efficacy and safety of sodium cantharidinate plus chemotherapy in non-small-cell lung cancer: A systematic review and meta-analysis of 38 randomized controlled trials

scientific article published on 19 September 2018

Dendrobium nobile Lindl alkaloid, a novel autophagy inducer, protects against axonal degeneration induced by Aβ25-35 in hippocampus neurons in vitro.

scientific article

Emulsified isoflurane anesthesia decreases brain-derived neurotrophic factor expression and induces cognitive dysfunction in adult rats

scientific article

Establishment of a cell-based drug screening model for identifying agonists of human peroxisome proliferator-activated receptor gamma (PPARγ).

scientific article

Evodiamine inhibits angiotensin II-induced rat cardiomyocyte hypertrophy.

scientific article

Gastrodin Attenuates Bilateral Common Carotid Artery Occlusion-Induced Cognitive Deficits via Regulating Aβ-Related Proteins and Reducing Autophagy and Apoptosis in Rats.

scientific article

Gastrodin ameliorates subacute phase cerebral ischemia‑reperfusion injury by inhibiting inflammation and apoptosis in rats

scientific article

Ginsenoside Rb₁ inhibits the carotid neointimal hyperplasia induced by balloon injury in rats via suppressing the phenotype modulation of vascular smooth muscle cells.

scientific article published on 21 April 2012

Ginsenoside Rg1 inhibits vascular intimal hyperplasia in balloon-injured rat carotid artery by down-regulation of extracellular signal-regulated kinase 2

scientific article published on 22 September 2011

Gypenosides attenuate cholesterol-induced DNA damage by inhibiting the production of reactive oxygen species in human umbilical vein endothelial cells

scientific article published on 16 December 2014

Has aidi injection the attenuation and synergistic efficacy to gemcitabine and cisplatin in non-small cell lung cancer? A meta-analysis of 36 randomized controlled trials.

scientific article

Hydrogen sulfide ameliorates learning memory impairment in APP/PS1 transgenic mice: A novel mechanism mediated by the activation of Nrf2.

scientific article published on 21 November 2016

Hydrogen sulfide attenuated tumor necrosis factor-α-induced inflammatory signaling and dysfunction in vascular endothelial cells.

scientific article

Hydrogen sulfide attenuates lipopolysaccharide-induced cognitive impairment: a pro-inflammatory pathway in rats

scientific article published on 22 April 2010

Hypoxia-Inducible Factor-1.ALPHA. Is Involved in the Pro-angiogenic Effect of Hydrogen Sulfide under Hypoxic Stress ⬇️

scientific article published on January 1, 2010

Icariin Attenuates OGD/R-Induced Autophagy via Bcl-2-Dependent Cross Talk between Apoptosis and Autophagy in PC12 Cells

scientific article published on 16 August 2016

Icariin attenuates cerebral ischemia-reperfusion injury through inhibition of inflammatory response mediated by NF-κB, PPARα and PPARγ in rats.

scientific article published on 8 December 2015

Icariin isolated from Epimedium brevicornum Maxim attenuates learning and memory deficits induced by d-galactose in rats.

scientific article published on June 2010

Icariin, a major constituent from Epimedium brevicornum, attenuates ibotenic acid-induced excitotoxicity in rat hippocampus.

scientific article published on 28 June 2016

Icariin, a major constituent of flavonoids from Epimedium brevicornum, protects against cognitive deficits induced by chronic brain hypoperfusion via its anti-amyloidogenic effect in rats.

scientific article published on 10 September 2015

Icariin, a phosphodiesterase-5 inhibitor, improves learning and memory in APP/PS1 transgenic mice by stimulation of NO/cGMP signalling.

scientific article published on 11 February 2014

Icariside II Ameliorates Cognitive Impairments Induced by Chronic Cerebral Hypoperfusion by Inhibiting the Amyloidogenic Pathway: Involvement of BDNF/TrkB/CREB Signaling and Up-Regulation of PPARα and PPARγ in Rats

scientific article published on 23 October 2018

Icariside II Effectively Reduces Spatial Learning and Memory Impairments in Alzheimer's Disease Model Mice Targeting Beta-Amyloid Production.

scientific article published on 08 March 2017

Icariside II alleviates oxygen-glucose deprivation and reoxygenation-induced PC12 cell oxidative injury by activating Nrf2/SIRT3 signaling pathway

scientific article published on 24 April 2018

Icariside II ameliorates ibotenic acid-induced cognitive impairment and apoptotic response via modulation of MAPK pathway in rats.

scientific article published on 31 January 2018

Icariside II attenuates lipopolysaccharide-induced neuroinflammation through inhibiting TLR4/MyD88/NF-κB pathway in rats

scientific article published on 24 December 2018

Icariside II protects against cerebral ischemia-reperfusion injury in rats via nuclear factor-κB inhibition and peroxisome proliferator-activated receptor up-regulation

scientific article

Icariside II, a Broad-Spectrum Anti-cancer Agent, Reverses Beta-Amyloid-Induced Cognitive Impairment through Reducing Inflammation and Apoptosis in Rats

scientific article published on 2 February 2017

Icariside II, a PDE5 inhibitor from Epimedium brevicornum, promotes neuron-like pheochromocytoma PC12 cell proliferation via activating NO/cGMP/PKG pathway

scientific article

Icariside II, a Phosphodiesterase-5 Inhibitor, Attenuates Beta-Amyloid-Induced Cognitive Deficits via BDNF/TrkB/CREB Signaling

scientific article published on 07 September 2018

Icariside II, a novel phosphodiesterase 5 inhibitor, protects against H2 O2 -induced PC12 cells death by inhibiting mitochondria-mediated autophagy

scientific article published on 19 September 2016

Icariside II, a novel phosphodiesterase-5 inhibitor, attenuates streptozotocin-induced cognitive deficits in rats.

scientific article published on 21 April 2016

Icariside II, a phosphodiesterase 5 inhibitor, attenuates cerebral ischaemia/reperfusion injury by inhibiting glycogen synthase kinase-3β-mediated activation of autophagy

scientific article published on 16 February 2020

Inhibitory effects of Dendrobium alkaloids on memory impairment induced by lipopolysaccharide in rats

scientific journal article

Involvement of stromal cell-derived factor-1α (SDF-1α), stem cell factor (SCF), fractalkine (FKN) and VEGF in TSG protection against intimal hyperplasia in rat balloon injury

scientific article published on 17 December 2018

Leonurine (SCM-198) attenuates myocardial fibrotic response via inhibition of NADPH oxidase 4

scientific article published on 02 November 2012

Leonurine (SCM-198) improves cardiac recovery in rat during chronic infarction.

scientific article published on 17 September 2010

Leonurine attenuates lipopolysaccharide-induced inflammatory responses in human endothelial cells: involvement of reactive oxygen species and NF-κB pathways

scientific article published on 28 January 2012

Leonurine protects against tumor necrosis factor-α-mediated inflammation in human umbilical vein endothelial cells

scientific article

Lithocarpus polystachyus Rehd. leaves aqueous extract protects against hydrogen peroxide‑induced SH-SY5Y cells injury through activation of Sirt3 signaling pathway

scientific article published on 05 October 2018

Neuroprotective effects of sodium hydrosulfide against β-amyloid-induced neurotoxicity.

scientific article published on 09 August 2016

Osthole attenuates focal inflammatory reaction following permanent middle cerebral artery occlusion in rats.

scientific article published on 8 August 2012

Protective effect of Ginkgo biloba leaf extract on learning and memory deficit induced by aluminum in model rats.

scientific article published in March 2006

Protective effect of ecdysterone on PC12 cells cytotoxicity induced by beta-amyloid25-35.

scientific article published in December 2005

Protective effects of Dendrobium nobile Lindl. alkaloids on amyloid beta (25-35)-induced neuronal injury

scientific article published on July 2017

Protective effects of icariin against learning and memory deficits induced by aluminium in rats.

scientific article

Protective effects of icariin on cognitive deficits induced by chronic cerebral hypoperfusion in rats.

scientific article published on 10 February 2009

Resveratrol, a neuroprotective supplement for Alzheimer's disease.

scientific article published on January 2012

Role of cystathionine γ-lyase/hydrogen sulfide pathway in cardiovascular disease: a novel therapeutic strategy?

scientific article

Rutaecarpine inhibits angiotensin II-induced proliferation in rat vascular smooth muscle cells.

scientific article published on 17 June 2013

S-Propargyl-cysteine (SPRC) attenuated lipopolysaccharide-induced inflammatory response in H9c2 cells involved in a hydrogen sulfide-dependent mechanism.

scientific article published on 10 February 2011

S-Propargyl-cysteine, a novel hydrogen sulfide-modulated agent, attenuates lipopolysaccharide-induced spatial learning and memory impairment: Involvement of TNF signaling and NF-κB pathway in rats ⬇️

scientific article published on September 7, 2010

S-propargyl-cysteine, a novel hydrogen sulfide-modulated agent, attenuated tumor necrosis factor-α-induced inflammatory signaling and dysfunction in endothelial cells

scientific article published on 10 January 2012

Sodium Hydrosulfide Attenuates Beta-Amyloid-Induced Cognitive Deficits and Neuroinflammation via Modulation of MAPK/NF-κB Pathway in Rats

scientific article published in January 2015

Sodium ferulate inhibits myocardial hypertrophy induced by abdominal coarctation in rats: Involvement of cardiac PKC and MAPK signaling pathways

scientific article published on 27 February 2019

Total Ginsenosides suppress the neointimal hyperplasia of rat carotid artery induced by balloon injury.

scientific article published on 25 December 2010

Total ginsenosides inhibit the right ventricular hypertrophy induced by monocrotaline in rats.

scientific article published in August 2008

Trilobatin Protects Against Oxidative Injury in Neuronal PC12 Cells Through Regulating Mitochondrial ROS Homeostasis Mediated by AMPK/Nrf2/Sirt3 Signaling Pathway

scientific article published on 30 July 2018

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