List of works - Jason Li

A pharmacogenomic approach validates AG-221 as an effective and on-target therapy in IDH2 mutant AML

scientific article published on 10 March 2017

A role for pericytes as microenvironmental regulators of human skin tissue regeneration

scientific article published on 03 August 2009

Altered significance of D'Amico risk classification in patients with prostate cancer linked to a familial breast cancer (kConFab) cohort

scientific article published on 6 April 2015

Alternative transcript initiation and splicing as a response to DNA damage

scientific article

Are there any more ovarian tumor suppressor genes? A new perspective using ultra high-resolution copy number and loss of heterozygosity analysis.

scientific article published in October 2009

Assessment of DNA methylation profiling and copy number variation as indications of clonal relationship in ipsilateral and contralateral breast cancers to distinguish recurrent breast cancer from a second primary tumour

scientific article published on 9 October 2015

BET-Bromodomain Inhibitors Engage the Host Immune System and Regulate Expression of the Immune Checkpoint Ligand PD-L1

scientific article

BRAF/NRAS wild-type melanomas have a high mutation load correlating with histologic and molecular signatures of UV damage

scientific article published on 5 July 2013

Bioinformatics pipelines for targeted resequencing and whole-exome sequencing of human and mouse genomes: a virtual appliance approach for instant deployment

scientific article

CONTRA: copy number analysis for targeted resequencing

scientific article

CoNVEX: copy number variation estimation in exome sequencing data using HMM

scientific article

Cooperation of the BTB-Zinc finger protein, Abrupt, with cytoskeletal regulators in Drosophila epithelial tumorigenesis

scientific article

DNA repair genes: alternative transcription and gene expression at the exon level in response to the DNA damaging agent, ionizing radiation

scientific article

Decreased Prostate Cancer-Specific Survival of Men withBRCA2 Mutations from Multiple Breast Cancer Families

scientific article published on 01 July 2011

EIF1AX and NRAS Mutations Co-occur and Cooperate in Low-Grade Serous Ovarian Carcinomas

scientific article published on 23 June 2017

Foxp3 expression in macrophages associated with RENCA tumors in mice.

scientific article

Functional Characterization of Quiescent Keratinocyte Stem Cells and Their Progeny Reveals a Hierarchical Organization in Human Skin Epidermis

scientific article published on 01 August 2011

Functional and molecular characterisation of EO771.LMB tumours, a new C57BL/6-mouse-derived model of spontaneously metastatic mammary cancer

scientific article

Gene function prediction based on genomic context clustering and discriminative learning: an application to bacteriophages

scientific article

Genome classification by gene distribution: an overlapping subspace clustering approach

scientific article

Genome-wide functional analysis reveals central signaling regulators of lymphatic endothelial cell migration and remodeling.

scientific article published on 3 October 2017

Genome-wide transcription responses to synchrotron microbeam radiotherapy

scientific article published on 13 September 2012

Genomic characterisation of Eμ-Myc mouse lymphomas identifies Bcor as a Myc co-operative tumour-suppressor gene

scientific article published on 06 March 2017

HDAC Inhibitor Panobinostat Engages Host Innate Immune Defenses to Promote the Tumoricidal Effects of Trastuzumab in HER2+ Tumors

scientific article

Homologous Recombination DNA Repair Pathway Disruption and Retinoblastoma Protein Loss Are Associated with Exceptional Survival in High-Grade Serous Ovarian Cancer.

scientific article

Id2 and E Proteins Orchestrate the Initiation and Maintenance of MLL-Rearranged Acute Myeloid Leukemia

scientific article published on 30 June 2016

Identification of Pik3ca Mutation as a Genetic Driver of Prostate Cancer That Cooperates with Pten Loss to Accelerate Progression and Castration-Resistant Growth

scientific article published on 26 March 2018

Identification of a radiation sensitivity gene expression profile in primary fibroblasts derived from patients who developed radiotherapy-induced fibrosis

scientific article published on 13 May 2014

Improving Training Speed of Support Vector Machines by Creating Exploitable Trends of Lagrangian Variables: An Application to DNA Splice Site Detection

Inferring copy number and genotype in tumour exome data

scientific article

Integrated mutation, copy number and expression profiling in resectable non-small cell lung cancer.

scientific article

Intraductal carcinoma of the prostate can evade androgen deprivation, with emergence of castrate-tolerant cells

scientific article published on 4 October 2017

Long term, continuous exposure to panobinostat induces terminal differentiation and long term survival in the TH-MYCN neuroblastoma mouse model

scientific article published on 23 February 2016

Loss of heterozygosity: what is it good for?

scientific article published on August 2015

Massively-parallel sequencing assists the diagnosis and guided treatment of cancers of unknown primary

scientific article published on December 2013

Molecular profiling of low grade serous ovarian tumours identifies novel candidate driver genes

scientific article published on 19 October 2015

Mutational landscape of mucinous ovarian carcinoma and its neoplastic precursors

scientific article published on 7 August 2015

Mutational profiling of familial male breast cancers reveals similarities with luminal A female breast cancer with rare TP53 mutations

scientific article

Next-generation sequence analysis of cancer xenograft models.

scientific article

PathOS: a decision support system for reporting high throughput sequencing of cancers in clinical diagnostic laboratories

scientific article

Patient-derived xenografts reveal that intraductal carcinoma of the prostate is a prominent pathology in BRCA2 mutation carriers with prostate cancer and correlates with poor prognosis.

scientific article published on 22 August 2014

Pericytes Promote Malignant Ovarian Cancer Progression in Mice and Predict Poor Prognosis in Serous Ovarian Cancer Patients.

scientific article published on 20 November 2015

Polynomial kernel adaptation and extensions to the SVM classifier learning

Prevalence of PALB2 mutations in Australian familial breast cancer cases and controls

scientific article

Reducing Sequence Artifacts in Amplicon-Based Massively Parallel Sequencing of Formalin-Fixed Paraffin-Embedded DNA by Enzymatic Depletion of Uracil-Containing Templates

scientific article published on 06 May 2013

Reevaluation of the BRCA2 truncating allele c.9976A > T (p.Lys3326Ter) in a familial breast cancer context

scientific article

Response of BRAF-mutant melanoma to BRAF inhibition is mediated by a network of transcriptional regulators of glycolysis

scientific article

Searching for candidate genes in familial BRCAX mutation carriers with prostate cancer.

scientific article published on 13 November 2015

Sequence artefacts in a prospective series of formalin-fixed tumours tested for mutations in hotspot regions by massively parallel sequencing

scientific article

Splice site identification using probabilistic parameters and SVM classification.

scientific article

Studying cancer genomics through next-generation DNA sequencing and bioinformatics.

scientific article published on January 2014

Survival Following Chemotherapy in Ovarian Clear Cell Carcinoma Is Not Associated with Pathological Misclassification of Tumor Histotype

scientific article published on 09 April 2019

TERT structural rearrangements in metastatic pheochromocytomas

scientific article published on 3 October 2017

Targeted-capture massively-parallel sequencing enables robust detection of clinically informative mutations from formalin-fixed tumours

scientific article published on 13 December 2013

The architecture and evolution of cancer neochromosomes

scientific article published on 10 November 2014

The genomic landscape of phaeochromocytoma

scientific article published on 2 February 2015

UV-Associated Mutations Underlie the Etiology of MCV-Negative Merkel Cell Carcinomas

scientific article published on 15 December 2015

Whole exome sequencing reveals activating JAK1 and STAT3 mutations in breast implant-associated anaplastic large cell lymphoma anaplastic large cell lymphoma

scientific article published on 19 May 2016

List of works by Jason Li

A pharmacogenomic approach validates AG-221 as an effective and on-target therapy in IDH2 mutant AML

A role for pericytes as microenvironmental regulators of human skin tissue regeneration

Altered significance of D'Amico risk classification in patients with prostate cancer linked to a familial breast cancer (kConFab) cohort

Alternative transcript initiation and splicing as a response to DNA damage

Are there any more ovarian tumor suppressor genes? A new perspective using ultra high-resolution copy number and loss of heterozygosity analysis.

Assessment of DNA methylation profiling and copy number variation as indications of clonal relationship in ipsilateral and contralateral breast cancers to distinguish recurrent breast cancer from a second primary tumour

BET-Bromodomain Inhibitors Engage the Host Immune System and Regulate Expression of the Immune Checkpoint Ligand PD-L1

BRAF/NRAS wild-type melanomas have a high mutation load correlating with histologic and molecular signatures of UV damage

Bioinformatics pipelines for targeted resequencing and whole-exome sequencing of human and mouse genomes: a virtual appliance approach for instant deployment

CONTRA: copy number analysis for targeted resequencing

CoNVEX: copy number variation estimation in exome sequencing data using HMM

Cooperation of the BTB-Zinc finger protein, Abrupt, with cytoskeletal regulators in Drosophila epithelial tumorigenesis

DNA repair genes: alternative transcription and gene expression at the exon level in response to the DNA damaging agent, ionizing radiation

Decreased Prostate Cancer-Specific Survival of Men withBRCA2 Mutations from Multiple Breast Cancer Families

EIF1AX and NRAS Mutations Co-occur and Cooperate in Low-Grade Serous Ovarian Carcinomas

Foxp3 expression in macrophages associated with RENCA tumors in mice.

Functional Characterization of Quiescent Keratinocyte Stem Cells and Their Progeny Reveals a Hierarchical Organization in Human Skin Epidermis

Functional and molecular characterisation of EO771.LMB tumours, a new C57BL/6-mouse-derived model of spontaneously metastatic mammary cancer

Gene function prediction based on genomic context clustering and discriminative learning: an application to bacteriophages

Genome classification by gene distribution: an overlapping subspace clustering approach

Genome-wide functional analysis reveals central signaling regulators of lymphatic endothelial cell migration and remodeling.

Genome-wide transcription responses to synchrotron microbeam radiotherapy

Genomic characterisation of Eμ-Myc mouse lymphomas identifies Bcor as a Myc co-operative tumour-suppressor gene

HDAC Inhibitor Panobinostat Engages Host Innate Immune Defenses to Promote the Tumoricidal Effects of Trastuzumab in HER2+ Tumors

Homologous Recombination DNA Repair Pathway Disruption and Retinoblastoma Protein Loss Are Associated with Exceptional Survival in High-Grade Serous Ovarian Cancer.

Id2 and E Proteins Orchestrate the Initiation and Maintenance of MLL-Rearranged Acute Myeloid Leukemia

Identification of Pik3ca Mutation as a Genetic Driver of Prostate Cancer That Cooperates with Pten Loss to Accelerate Progression and Castration-Resistant Growth

Identification of a radiation sensitivity gene expression profile in primary fibroblasts derived from patients who developed radiotherapy-induced fibrosis

Improving Training Speed of Support Vector Machines by Creating Exploitable Trends of Lagrangian Variables: An Application to DNA Splice Site Detection

Inferring copy number and genotype in tumour exome data

Integrated mutation, copy number and expression profiling in resectable non-small cell lung cancer.

Intraductal carcinoma of the prostate can evade androgen deprivation, with emergence of castrate-tolerant cells

Long term, continuous exposure to panobinostat induces terminal differentiation and long term survival in the TH-MYCN neuroblastoma mouse model

Loss of heterozygosity: what is it good for?

Massively-parallel sequencing assists the diagnosis and guided treatment of cancers of unknown primary

Molecular profiling of low grade serous ovarian tumours identifies novel candidate driver genes

Mutational landscape of mucinous ovarian carcinoma and its neoplastic precursors

Mutational profiling of familial male breast cancers reveals similarities with luminal A female breast cancer with rare TP53 mutations

Next-generation sequence analysis of cancer xenograft models.

PathOS: a decision support system for reporting high throughput sequencing of cancers in clinical diagnostic laboratories

Patient-derived xenografts reveal that intraductal carcinoma of the prostate is a prominent pathology in BRCA2 mutation carriers with prostate cancer and correlates with poor prognosis.

Pericytes Promote Malignant Ovarian Cancer Progression in Mice and Predict Poor Prognosis in Serous Ovarian Cancer Patients.

Polynomial kernel adaptation and extensions to the SVM classifier learning

Prevalence of PALB2 mutations in Australian familial breast cancer cases and controls

Reducing Sequence Artifacts in Amplicon-Based Massively Parallel Sequencing of Formalin-Fixed Paraffin-Embedded DNA by Enzymatic Depletion of Uracil-Containing Templates

Reevaluation of the BRCA2 truncating allele c.9976A > T (p.Lys3326Ter) in a familial breast cancer context

Response of BRAF-mutant melanoma to BRAF inhibition is mediated by a network of transcriptional regulators of glycolysis

Searching for candidate genes in familial BRCAX mutation carriers with prostate cancer.

Sequence artefacts in a prospective series of formalin-fixed tumours tested for mutations in hotspot regions by massively parallel sequencing

Splice site identification using probabilistic parameters and SVM classification.

Studying cancer genomics through next-generation DNA sequencing and bioinformatics.

Survival Following Chemotherapy in Ovarian Clear Cell Carcinoma Is Not Associated with Pathological Misclassification of Tumor Histotype

TERT structural rearrangements in metastatic pheochromocytomas

Targeted-capture massively-parallel sequencing enables robust detection of clinically informative mutations from formalin-fixed tumours

The architecture and evolution of cancer neochromosomes

The genomic landscape of phaeochromocytoma

UV-Associated Mutations Underlie the Etiology of MCV-Negative Merkel Cell Carcinomas

Whole exome sequencing reveals activating JAK1 and STAT3 mutations in breast implant-associated anaplastic large cell lymphoma anaplastic large cell lymphoma