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List of works by Mingyao Liu

(-)-Gossypol suppresses the growth of human prostate cancer xenografts via modulating VEGF signaling-mediated angiogenesis.

scientific article published on 3 March 2011

1'-Acetoxychavicol acetate suppresses angiogenesis-mediated human prostate tumor growth by targeting VEGF-mediated Src-FAK-Rho GTPase-signaling pathway ⬇️

scientific article published on March 22, 2011

5-Fluoruracil blocked giant cell tumor progression by suppressing osteoclastogenesis through NF-kappaB signals and blocking angiogenesis.

scientific article published on 5 May 2015

A B cell-dependent pathway drives chronic lung allograft rejection after ischemia-reperfusion injury in mice

scientific article published on 26 August 2019

A GABAergic system in airway epithelium is essential for mucus overproduction in asthma

scientific article

A Method for Translational Rat Ex vivoLung Perfusion Experimentation

scientific article published on 01 April 2020

A hybrid of thiazolidinone with the hydroxamate scaffold for developing novel histone deacetylase inhibitors with antitumor activities

scientific article published on 6 January 2016

A natural small molecule harmine inhibits angiogenesis and suppresses tumour growth through activation of p53 in endothelial cells.

scientific article

A note on CYP2J2-mediated terfenadine hydroxylation in human liver microsomes

scientific article published on 02 July 2014

A novel combined ex vivo and in vivo lentiviral interleukin-10 gene delivery strategy at the time of transplantation decreases chronic lung allograft rejection in mice

article

A novel human SCAN/(Cys)2(His)2 zinc-finger transcription factor ZNF323 in early human embryonic development.

scientific article

A novel human gene ZNF415 with five isoforms inhibits AP-1- and p53-mediated transcriptional activity

scientific article published on 09 October 2006

A novel human zinc finger protein ZNF540 interacts with MVP and inhibits transcriptional activities of the ERK signal pathway

scientific article

A novel model for post-transplant obliterative airway disease reveals angiogenesis from the pulmonary circulation

scientific article published on 01 February 2005

A novel model to study bacterial adherence to the transplanted airway: inhibition of Burkholderia cepacia adherence to human airway by dextran and xylitol.

scientific article published in December 2004

A novel mutation of TGF beta1 in a Chinese family with Camurati-Engelmann disease

scientific article published on 06 March 2007

A novel mutation of p63 in a Chinese family with inherited syndactyly and adactylism.

scientific article published on 26 August 2007

A novel six-transmembrane protein hhole functions as a suppressor in MAPK signaling pathways.

scientific article

A novel synthetic small molecule YH-306 suppresses colorectal tumour growth and metastasis via FAK pathway

scientific article

A simplified model for en bloc double lung xenotransplantation from hamster to rat

scientific article published on 01 February 2002

ARDS and knowledge translation

scientific article published on 09 February 2008

Accommodation after lung xenografting from hamster to rat.

scientific article published in March 2003

Acetyl-11-keto-beta-boswellic acid inhibits prostate tumor growth by suppressing vascular endothelial growth factor receptor 2-mediated angiogenesis ⬇️

scientific article published on 30 June 2009

Acetyl‐11‐keto‐β‐boswellic acid suppresses invasion of pancreatic cancer cells through the downregulation of CXCR4 chemokine receptor expression ⬇️

scientific article published on March 29, 2011

Actin filament associated protein mediates c-Src related SRE/AP-1 transcriptional activation

scientific article published on 12 January 2011

Activated protein C in ischemia-reperfusion injury after experimental lung transplantation

scientific article published on 26 September 2009

Activating transcription factor 3 confers protection against ventilator-induced lung injury.

scientific article published on 22 April 2010

Activation of Toll-like receptor 5 on breast cancer cells by flagellin suppresses cell proliferation and tumor growth

scientific article

Activation of mitogen-activated protein kinases during human lung transplantation

scientific article published on 08 August 2005

Acute lung injury and cell death: how many ways can cells die?

scientific article published on 18 January 2008

Acute lung injury: a yellow card for engineered nanoparticles?

scientific article

Adaptor protein XB130 is a Rac-controlled component of lamellipodia that regulates cell motility and invasion.

scientific article

Adenovirus-mediated interleukin-10 gene transfer inhibits post-transplant fibrous airway obliteration in an animal model of bronchiolitis obliterans

article

Aerosolised surfactant generated by a novel noninvasive apparatus reduced acute lung injury in rats

scientific article

Af17 deficiency increases sodium excretion and decreases blood pressure

scientific journal article

Allograft airway fibrosis in the pulmonary milieu: a disorder of tissue remodeling

scientific article published on 01 March 2008

Altered Profile of Circulating Endothelial-Derived Microparticles in Ventilator-Induced Lung Injury.

scientific article published on 25 August 2015

Alveolar recruitment prevents rapid-reperfusion-induced injury of lung transplants

scientific article published on 01 November 1999

Amelioration of acute graft-versus-host disease by adoptive transfer of ex vivo expanded human cord blood CD4+CD25+ forkhead box protein 3+ regulatory T cells is associated with the polarization of Treg/Th17 balance in a mouse model

scientific article published on 21 November 2011

Amino Acid Structure Determines the Immune Responses Generated by Peptide-Gold Nanoparticle Hybrids

article

Amino Acid-Dependent Attenuation of Toll-like Receptor Signaling by Peptide-Gold Nanoparticle Hybrids

scientific article

An extracellular oxygen carrier during prolonged pulmonary preservation improves post-transplant lung function

scientific article published on 10 April 2020

Anacardic acid (6-pentadecylsalicylic acid) inhibits tumor angiogenesis by targeting Src/FAK/Rho GTPases signaling pathway.

scientific article

Annexin V homodimer protects against ischemia reperfusion-induced acute lung injury in lung transplantation

scientific article published on 11 November 2015

Anti-human tissue factor antibody ameliorated intestinal ischemia reperfusion-induced acute lung injury in human tissue factor knock-in mice

scientific article

Anti-inflammatory therapies: application of molecular biology techniques in intensive care medicine ⬇️

scientific article published on July 1, 1997

Antitumor action of a novel histone deacetylase inhibitor, YF479, in breast cancer

scientific article

Atypical protein kinase C in cell motility.

scientific article published on 25 October 2012

Bench-to-bedside review: Biotrauma and modulation of the innate immune response.

scientific article

Bile acid aspiration and the development of bronchiolitis obliterans after lung transplantation.

scientific article

Bio-stretch, a computerized cell strain apparatus for three-dimensional organotypic cultures

scientific article published on 01 February 1999

Biological effects of Tat cell-penetrating peptide: a multifunctional Trojan horse?

scientific article published in January 2014

Bortezomib Inhibits Giant Cell Tumor of Bone through Induction of Cell Apoptosis and Inhibition of Osteoclast Recruitment, Giant Cell Formation, and Bone Resorption.

scientific article published on 9 February 2016

Brain death and Toll-like receptors in lung transplantation.

scientific article

Butein, a tetrahydroxychalcone, suppresses cancer‐induced osteoclastogenesis through inhibition of receptor activator of nuclear factor‐kappaB ligand signaling ⬇️

scientific article published on March 11, 2011

CRISPR/Cas9-mediated somatic correction of a novel coagulator factor IX gene mutation ameliorates hemophilia in mouse

scientific article published on 10 March 2016

Caffeic acid 3,4-dihydroxy-phenethyl ester induces cancer cell senescence by suppressing twist expression.

scientific article

Caffeic acid 3,4-dihydroxy-phenethyl ester suppresses receptor activator of NF-κB ligand–induced osteoclastogenesis and prevents ovariectomy-induced bone loss through inhibition of mitogen-activated protein kinase/activator protein 1 and Ca2+–nuclea

scientific article

Caspase inhibition improves ischemia-reperfusion injury after lung transplantation

scientific article published on 01 February 2005

Ccndbp1 is a new positive regulator of skeletal myogenesis

scientific article published on 27 May 2016

Celastrol suppresses invasion of colon and pancreatic cancer cells through the downregulation of expression of CXCR4 chemokine receptor.

scientific article

Cell death in human lung transplantation: apoptosis induction in human lungs during ischemia and after transplantation.

scientific article

Cell-based tissue engineering for lung regeneration

scientific article published on 6 October 2006

Characterization of novel cytochrome P450 2E1 knockout rat model generated by CRISPR/Cas9.

scientific article

Chemokine receptors and their therapeutic opportunities in diseased lung: far beyond leukocyte trafficking

scientific article

Chromosome Condensation 1-Like (Chc1L) Is a Novel Tumor Suppressor Involved in Development of Histiocyte-Rich Neoplasms

scientific article published on 20 August 2015

Circulating Cell Death Biomarkers May Predict Survival in Human Lung Transplantation.

scientific article

Claudin 1 mediates TNFα-induced gene expression and cell migration in human lung carcinoma cells

scientific article

Claudin 1 mediates tumor necrosis factor alpha-induced cell migration in human gastric cancer cells

scientific article

Cloning and expression of a novel human gene, Isl-2, encoded a LIM-homeodomain protein

scientific article

Comparative analysis of human protein-coding and noncoding RNAs between brain and 10 mixed cell lines by RNA-Seq.

scientific article

Comparative study of regulatory T cells expanded ex vivo from cord blood and adult peripheral blood

scientific article published on 01 June 2012

Conversion of mechanical force into biochemical signaling

scientific article

Correction to Electrospun Micropatterned Nanocomposites Incorporated with Cu2S Nanoflowers for Skin Tumor Therapy and Wound Healing

scientific article published on 05 March 2019

Crystal structure of LGR4-Rspo1 complex: insights into the divergent mechanisms of ligand recognition by leucine-rich repeat G-protein-coupled receptors (LGRs).

scientific article

Cucurbitacin E inhibits breast tumor metastasis by suppressing cell migration and invasion

scientific article published on July 28, 2012

Cucurbitacin E, a tetracyclic triterpenes compound from Chinese medicine, inhibits tumor angiogenesis through VEGFR2-mediated Jak2-STAT3 signaling pathway.

scientific article

Cudratricusxanthone G inhibits human colorectal carcinoma cell invasion by MMP-2 down-regulation through suppressing activator protein-1 activity ⬇️

scientific article published on March 4, 2011

DNA microarray analysis of gene expression in alveolar epithelial cells in response to TNFalpha, LPS, and cyclic stretch.

scientific article published on 28 September 2004

De novo synthesize of bile acids in pulmonary arterial hypertension lung.

scientific article published on 11 April 2014

Defeat mutant KRAS with synthetic lethality

scientific article published on 27 July 2016

Deletion of G protein-coupled receptor 48 leads to ocular anterior segment dysgenesis (ASD) through down-regulation of Pitx2.

scholarly article

Design and optimization of hybrid of 2,4-diaminopyrimidine and arylthiazole scaffold as anticancer cell proliferation and migration agents.

scientific article published on 13 April 2015

Design, synthesis and anticancer activities of novel otobain derivatives

scientific article published on 23 November 2015

Development of a validated LC-MS/MS method for the determination of ailanthone in rat plasma with application to pharmacokinetic study

scientific article published on 31 October 2014

Differential gene profiling in acute lung injury identifies injury-specific gene expression.

scientific article published on March 2008

Differential proteomic analysis of bronchoalveolar lavage fluid from lung transplant patients with and without chronic graft dysfunction

article

Discovery and Characterization of 1H-1,2,3-Triazole Derivatives as Novel Prostanoid EP4 Receptor Antagonists for Cancer Immunotherapy

scientific article published on 02 January 2020

Distinct expression patterns of alveolar "alarmins" in subtypes of chronic lung allograft dysfunction

scientific article published on 01 May 2014

Donor bronchial wash bile acid and suitability of donor lungs for transplantation

scientific article published on 12 August 2017

Donor prone positioning protects lungs from injury during warm ischemia

scientific article published on 25 April 2019

Donor-recipient gender mismatch in lung transplantation: Impact on obliterative bronchiolitis and survival

scientific article published on 01 November 2005

Drosophila TCTP is essential for growth and proliferation through regulation of dRheb GTPase

scientific article

Effect of complement inhibition with soluble complement receptor 1 on pig allotransplant lung function

scientific article

Effect of ventilator-induced lung injury on the development of reperfusion injury in a rat lung transplant model

scientific article published in December 2002

Effective delivery of a rationally designed intracellular peptide drug with gold nanoparticle-peptide hybrids

scientific article published on 7 July 2015

Effects of Warm Versus Cold Ischemic Donor Lung Preservation on the Underlying Mechanisms of Injuries During Ischemia and Reperfusion

scientific article published on 01 May 2018

Effects of cucurbitacin e, a tetracyclic triterpene compound from Cucurbitaceae, on the pharmacokinetics and pharmacodynamics of warfarin in rats.

scientific article published on 13 October 2014

Efficient gene delivery to pig airway epithelia and submucosal glands using helper-dependent adenoviral vectors

scientific article published on 08 October 2013

Efficient liver repopulation of transplanted hepatocyte prevents cirrhosis in a rat model of hereditary tyrosinemia type I

scientific article published on 11 August 2016

Efficient photoactivatable Dre recombinase for cell type-specific spatiotemporal control of genome engineering in the mouse

scientific article published on 14 December 2020

Endosomal pH modulation by peptide-gold nanoparticle hybrids enables potent anti-inflammatory activity in phagocytic immune cells

scientific article published on 3 October 2016

Evaluating the pharmacological mechanism of Chinese medicine Si-Wu-Tang through multi-level data integration

scientific article (publication date: 2013)

Evaluation of enzyme inhibition kinetics in drug-drug interactions

scientific article published on 23 October 2014

Evaluation of the inhibition potential of plumbagin against cytochrome P450 using LC-MS/MS and cocktail approach

scientific article published on 22 June 2016

Ex Vivo Perfusion Treatment of Infection in Human Donor Lungs.

scientific article

Ex vivo adenoviral vector gene delivery results in decreased vector-associated inflammation pre- and post-lung transplantation in the pig.

scientific article

Expression of a novel Krüpple-like zinc-finger gene, ZNF382, in human heart.

scientific article

Extension of donor lung preservation with hypothermic storage after normothermic ex vivo lung perfusion

scientific article published on 10 June 2015

Extracellular UDP and P2Y6 function as a danger signal to protect mice from vesicular stomatitis virus infection through an increase in IFN-β production

scientific article published on 26 September 2014

Fe2+-catalyzed non-enzymatic glycosylation alters collagen conformation during AGE-collagen formation in vitro.

scientific article published on 21 September 2007

Formulation of hydrophobic therapeutics with self-assembling peptide and amino acid: A new platform for intravenous drug delivery

scientific article published on 29 August 2016

Fractal circuit sensors enable rapid quantification of biomarkers for donor lung assessment for transplantation

scientific article published on 28 August 2015

From a Designer Drug to the Discovery of Selective Cannabinoid Type 2 Receptor Agonists with Favorable Pharmacokinetic Profiles for the Treatment of Systemic Sclerosis

scientific article published on 31 December 2020

Functional interrelationship between the WASF3 and KISS1 metastasis-associated genes in breast cancer cells.

scientific article

Functional repair of human donor lungs by IL-10 gene therapy.

scientific article published in October 2009

Functions of type II pneumocyte-derived vascular endothelial growth factor in alveolar structure, acute inflammation, and vascular permeability.

scientific article published on 18 February 2010

G-protein-activated phospholipase C-beta, new partners for cell polarity proteins Par3 and Par6.

scientific article

GCIP/CCNDBP1, a helix-loop-helix protein, suppresses tumorigenesis.

scientific article published on April 2007

GGAP2/PIKE-a directly activates both the Akt and nuclear factor-kappaB pathways and promotes prostate cancer progression.

scientific article published on 27 January 2009

GPR116, an adhesion G-protein-coupled receptor, promotes breast cancer metastasis via the Gαq-p63RhoGEF-Rho GTPase pathway.

scientific article published on 5 September 2013

GPR126 protein regulates developmental and pathological angiogenesis through modulation of VEGFR2 receptor signaling

scientific article (publication date: 12 December 2014)

GPR48-Induced keratinocyte proliferation occurs through HB-EGF mediated EGFR transactivation.

scientific article published on 21 August 2010

Gambogic acid inhibits angiogenesis and prostate tumor growth by suppressing vascular endothelial growth factor receptor 2 signaling.

scientific article published on March 2008

Gene expression profiling in the lungs of patients with pulmonary hypertension associated with pulmonary fibrosis.

scientific article published on 11 August 2011

Generation of site-specific mutations in the rat genome via CRISPR/Cas9.

scientific article published in January 2014

Gossypin, a pentahydroxy glucosyl flavone, inhibits the transforming growth factor beta-activated kinase-1-mediated NF-kappaB activation pathway, leading to potentiation of apoptosis, suppression of invasion, and abrogation of osteoclastogenesis.

scientific article published in March 2007

Gpr97 is dispensable for metabolic syndrome but is involved in macrophage inflammation in high-fat diet-induced obesity in mice.

scientific article published on 19 April 2016

Green tea polyphenol blocks h(2)o(2)-induced interleukin-8 production from human alveolar epithelial cells.

scientific article published on June 2002

Halofuginone treatment reduces interleukin-17A and ameliorates features of chronic lung allograft dysfunction in a mouse orthotopic lung transplant model

scientific article published on 10 December 2015

Haploinsufficiency in the prometastasis Kiss1 receptor Gpr54 delays breast tumor initiation, progression, and lung metastasis

scientific article published on 18 August 2011

Hierarchically micro-patterned nanofibrous scaffolds with a nanosized bio-glass surface for accelerating wound healing.

scientific article published on 27 October 2015

High-volume ventilation induces pentraxin 3 expression in multiple acute lung injury models in rats

scientific article published on 25 August 2006

Higher M30 and high mobility group box 1 protein levels in ex vivo lung perfusate are associated with primary graft dysfunction after human lung transplantation

scientific article published on 21 June 2017

Hispidulin, a small flavonoid molecule, suppresses the angiogenesis and growth of human pancreatic cancer by targeting vascular endothelial growth factor receptor 2-mediated PI3K/Akt/mTOR signaling pathway.

scientific article published on 19 November 2010

History and current status of evidence-based korean medicine

scientific article

Human neutrophil peptides and phagocytic deficiency in bronchiectatic lungs.

scientific article published on 30 April 2009

Human α1-antitrypsin improves early post-transplant lung function: Pre-clinical studies in a pig lung transplant model

scientific article published on 23 March 2016

IXL, a new subunit of the mammalian Mediator complex, functions as a transcriptional suppressor.

scientific article

Identification and characterization of mouse metastasis-suppressor KiSS1 and its G-protein-coupled receptor

scientific journal article

Identification and characterization of two novel zinc finger genes, ZNF359 and ZFP28, in human development.

scientific article

Identification of Genes Involved in Breast Cancer Metastasis by Integrating Protein-Protein Interaction Information with Expression Data

scientific article

Impact of cytokine expression in the pre-implanted donor lung on the development of chronic lung allograft dysfunction subtypes.

scientific article published on 24 October 2013

Impact of human donor lung gene expression profiles on survival after lung transplantation: a case-control study

scientific article published on 22 August 2008

Impact of human interleukin-10 on vector-induced inflammation and early graft function in rat lung transplantation.

scientific article published in May 2003

Importance of left atrial pressure during ex vivo lung perfusion

scientific article

In vitro and in vivo evaluation of cucurbitacin E on rat hepatic CYP2C11 expression and activity using LC-MS/MS.

scientific article

In vivo selection for spine-derived highly metastatic lung cancer cells is associated with increased migration, inflammation and decreased adhesion.

scientific article

In vivo transtracheal adenovirus-mediated transfer of human interleukin-10 gene to donor lungs ameliorates ischemia-reperfusion injury and improves early posttransplant graft function in the rat.

scientific article

Inactivating hepatitis C virus in donor lungs using light therapies during normothermic ex vivo lung perfusion

scientific article published in Nature Communications

Increased Arginase Expression and Decreased Nitric Oxide in Pig Donor Lungs after Normothermic Ex Vivo Lung Perfusion

scientific article published on 14 February 2020

Increased expression of prostate-specific G-protein-coupled receptor in human prostate intraepithelial neoplasia and prostate cancers.

scientific article

Increased levels of interleukin-1β and tumor necrosis factor-α in donor lungs rejected for transplantation.

scientific article published on 15 January 2011

Indirubin inhibits tumor growth by antitumor angiogenesis via blocking VEGFR2-mediated JAK/STAT3 signaling in endothelial cell.

scientific article

Induction of SENP1 in Endothelial Cells Contributes to Hypoxia-driven VEGF Expression and Angiogenesis ⬇️

scientific article published on September 14, 2010

Influence of mechanical stretch on thrombin regulation by fetal mixed lung cells

scientific article published on 01 September 1998

Inhaled carbon monoxide confers antiinflammatory effects against ventilator-induced lung injury.

scientific article

Inhibiting cytoplasmic accumulation of HuR synergizes genotoxic agents in urothelial carcinoma of the bladder.

scientific article published on 09 June 2016

Inhibition of Breast Cancer Metastases by a Novel Inhibitor of TGFβ Receptor 1 ⬇️

scientific article published on November 24, 2012

Inhibition of Osteoclastogenesis and Bone Resorption in vitro and in vivo by a prenylflavonoid xanthohumol from hops

scientific article

Inhibition of STAT3 signaling pathway by nitidine chloride suppressed the angiogenesis and growth of human gastric cancer.

scientific article

Inhibition of angiotensin-converting enzyme by captopril: a novel approach to reduce ischemia-reperfusion injury after lung transplantation

scientific article published on 01 September 2000

Inhibition of breast cancer progression by a novel histone deacetylase inhibitor, LW479, by down-regulating EGFR expression.

scientific article published on 12 June 2015

Inhibition of mechanical strain-induced fetal rat lung cell proliferation by gadolinium, a stretch-activated channel blocker

scientific article published on 01 December 1994

Inhibition of pulmonary surfactant function by meconium

scientific article published on 01 February 1991

Inhibition of regulated necrosis attenuates receptor-interacting protein kinase 1-mediated ischemia-reperfusion injury after lung transplantation

scientific article published on 26 April 2018

Inhibitory effects of celastrol on rat liver cytochrome P450 1A2, 2C11, 2D6, 2E1 and 3A2 activity.

scientific article

Injurious mechanical ventilation and end-organ epithelial cell apoptosis and organ dysfunction in an experimental model of acute respiratory distress syndrome.

scientific article published on April 2003

Innate immunity and organ transplantation: the potential role of toll-like receptors.

scientific article

Instability of cytokines at body temperature

scientific article published on 01 April 2005

Intercellular adhesion molecule-1 mediates cellular cross-talk between parenchymal and immune cells after lipopolysaccharide neutralization.

scientific article published on January 2004

Interleukin 10 gene transfection of donor lungs ameliorates posttransplant cell death by a switch from cellular necrosis to apoptosis

scientific article published in October 2003

Interleukin-8 release during early reperfusion predicts graft function in human lung transplantation

scientific article published on 01 January 2002

Intestinal ischemia-reperfusion-induced acute lung injury and oncotic cell death in multiple organs

scientific article published on 01 August 2007

Investigation of cytochrome P450 inhibitory properties of maslinic acid, a bioactive compound from Olea europaea L., and its structure-activity relationship

scientific article published on 23 October 2014

Involvement of protein tyrosine kinase in osmoregulation of Na(+) transport and membrane capacitance in renal A6 cells.

scientific article

Ischemia-reperfusion decreases protein tyrosine phosphorylation and p38 mitogen-activated protein kinase phosphorylation in rat lung transplants.

scientific article published in March 2003

Ischemia-reperfusion induces death receptor-independent necroptosis via calpain-STAT3 activation in a lung transplant setting

scientific article published on 19 July 2018

Ischemia-reperfusion-induced lung injury.

scientific article

KiSS1 and its G-protein-coupled receptor GPR54 in cancer development and metastasis ⬇️

scientific article published on December 1, 2012

KiSS1 suppresses TNFalpha-induced breast cancer cell invasion via an inhibition of RhoA-mediated NF-kappaB activation.

scientific article published on August 2009

Kinetics of lactate metabolism during acellular normothermic ex vivo lung perfusion

scientific article published on 17 September 2011

Knowledge translation: airway epithelial cell migration and respiratory diseases ⬇️

scientific article published on June 21, 2012

LGR4 is a receptor for RANKL and negatively regulates osteoclast differentiation and bone resorption.

scientific article

LGR4/GPR48 inactivation leads to aniridia-genitourinary anomalies-mental retardation syndrome defects.

scientific article published on 11 February 2014

Lentiviral interleukin-10 gene therapy: Safety and questions

scientific article published on 01 February 2019

Lentivirus IL-10 gene therapy down-regulates IL-17 and attenuates mouse orthotopic lung allograft rejection.

scientific article

Lgr4 is a key regulator of prostate development and prostate stem cell differentiation.

scientific article

Lgr4 protein deficiency induces ataxia-like phenotype in mice and impairs long term depression at cerebellar parallel fiber-Purkinje cell synapses

scientific article

Lgr4 regulates mammary gland development and stem cell activity through the pluripotency transcription factor Sox2.

scientific article published on September 2013

Lgr4/Gpr48 negatively regulates TLR2/4-associated pattern recognition and innate immunity by targeting CD14 expression

scientific journal article

Linifanib (ABT-869) Potentiates the Efficacy of Chemotherapeutic Agents through the Suppression of Receptor Tyrosine Kinase-Mediated AKT/mTOR Signaling Pathways in Gastric Cancer.

scientific article published on 08 July 2016

Lipid Receptor G2A-Mediated Signal Pathway Plays a Critical Role in Inflammatory Response by Promoting Classical Macrophage Activation

scientific article published in 2021

Local long-term expression of lentivirally delivered IL-10 in the lung attenuates obliteration of intrapulmonary allograft airways.

scientific article

Long pentraxin 3 in pulmonary infection and acute lung injury.

scientific article published on 2 February 2007

Long pentraxin PTX3 deficiency worsens LPS-induced acute lung injury

scientific article published on 12 November 2010

Low invasive in vivo tissue sampling for monitoring biomarkers and drugs during surgery.

scientific article published on 31 March 2014

Low-dose computed tomography volumetry for subtyping chronic lung allograft dysfunction

scientific article published on 13 August 2015

Lung Lavage and Surfactant Replacement During Ex Vivo Lung Perfusion for Treatment of Gastric Acid Aspiration-Induced Donor Lung Injury

scientific article

Lung regeneration: implantation of fetal rat lung fragments into adult rat lung parenchyma

scientific article published on 01 May 2006

Lycorine is a novel inhibitor of the growth and metastasis of hormone-refractory prostate cancer.

scientific article

Lymphocytic airway infiltration as a precursor to fibrous obliteration in a rat model of bronchiolitis obliterans

scientific article published on 01 July 1997

MEK/ERK pathway mediates PKC activation-induced recruitment of PKCζ and MMP-9 to podosomes.

scientific article

Maslinic acid potentiates the anti-tumor activity of tumor necrosis factor alpha by inhibiting NF-kappaB signaling pathway

scientific article

Maslinic acid suppresses osteoclastogenesis and prevents ovariectomy-induced bone loss by regulating RANKL-mediated NF-κB and MAPK signaling pathways.

scientific article published on March 2011

Measurement of Rhodamine 123 in Three-Dimensional Organoids: A Novel Model for P-Glycoprotein Inhibitor Screening

scientific article published on 6 April 2016

Mechanical stress induces lung fibrosis by epithelial-mesenchymal transition.

scientific article published on February 2012

Meet Our Associate Editor

scientific article published on 01 January 2015

Mesenchymal stem cell treatment is associated with decreased perfusate concentration of interleukin-8 during ex vivo perfusion of donor lungs after 18-hour preservation

scientific article published on 6 May 2016

Mesenchymal stromal cell therapy during ex vivo lung perfusion ameliorates ischemia-reperfusion injury in lung transplantation

scientific article published on 26 July 2019

Metabolic Profile of Ex Vivo Lung Perfusate Yields Biomarkers for Lung Transplant Outcomes

scientific article published in January 2018

Metabolomic heterogeneity of pulmonary arterial hypertension

scientific article

Methyl 2-cyano-3,11-dioxo-18-olean-1,12-dien-30-oate (CDODA-Me), a derivative of glycyrrhetinic acid, functions as a potent angiogenesis inhibitor.

scientific article

MiR-93 enhances angiogenesis and metastasis by targeting LATS2.

scientific article published on 30 October 2012

Microarray meta-analysis identifies acute lung injury biomarkers in donor lungs that predict development of primary graft failure in recipients

scientific article

Modification and Biological Evaluation of a Series of 1,5-Diaryl-1,2,4-triazole Compounds as Novel Agents against Pancreatic Cancer Metastasis through Targeting Myoferlin

scientific article published on 08 May 2019

Modified In Vivo Lung Perfusion for Local Chemotherapy: A Preclinical Study With Doxorubicin.

scientific article published on 4 March 2016

Modified in vivo lung perfusion allows for prolonged perfusion without acute lung injury.

scientific article published on 27 November 2013

Molecular cloning of actin filament-associated protein: a putative adaptor in stretch-induced Src activation

scientific journal article

Morelloflavone blocks injury-induced neointimal formation by inhibiting vascular smooth muscle cell migration.

scientific article

Neutrophil extracellular traps in ex vivo lung perfusion perfusate predict the clinical outcome of lung transplant recipients

scientific article published on 04 April 2019

New Avenues for Nanoparticle-Related Therapies.

scientific article

New functions and signaling mechanisms for the class of adhesion G protein-coupled receptors.

scientific article

New insights into the androgen biotransformation in prostate cancer: A regulatory network among androgen, androgen receptors and UGTs

scientific article published on 26 February 2016

Norcantharidin facilitates LPS-mediated immune responses by up-regulation of AKT/NF-κB signaling in macrophages

scientific article

Normothermic ex vivo lung perfusion in clinical lung transplantation

scientific article published on 01 April 2011

Normothermic ex vivo perfusion prevents lung injury compared to extended cold preservation for transplantation

scientific article published on 06 August 2009

Optimization of 2-(3-(arylalkyl amino carbonyl) phenyl)-3-(2-methoxyphenyl)-4-thiazolidinone derivatives as potent antitumor growth and metastasis agents.

scientific article published on 24 April 2014

Oridonin inhibits tumor growth and metastasis through anti-angiogenesis by blocking the Notch signaling

scientific article

P2Y(6) agonist uridine 5'-diphosphate promotes host defense against bacterial infection via monocyte chemoattractant protein-1-mediated monocytes/macrophages recruitment.

scientific article

PAK1IP1, a ribosomal stress-induced nucleolar protein, regulates cell proliferation via the p53-MDM2 loop.

scientific article

PKC Activation Induces Inflammatory Response and Cell Death in Human Bronchial Epithelial Cells ⬇️

scientific article published on May 17, 2013

PKCδ-iPLA2-PGE2-PPARγ signaling cascade mediates TNF-α induced Claudin 1 expression in human lung carcinoma cells

scientific article

PTX3 as a potential biomarker of acute lung injury: supporting evidence from animal experimentation.

scientific article

Pentraxin 3 deficiency enhances features of chronic rejection in a mouse orthotopic lung transplantation model

scientific article published on 3 January 2018

Phenotypic diversity within a Pseudomonas aeruginosa population infecting an adult with cystic fibrosis

scientific article published on 5 June 2015

Phorbol ester-induced podosomes in normal human bronchial epithelial cells.

scientific article published on February 2009

Physiologic assessment of the ex vivo donor lung for transplantation.

scientific article published in October 2012

Pig lung transplant survival model

scientific article published on 01 August 2018

Pilot study exploring lung allograft surfactant protein A (SP-A) expression in association with lung transplant outcome.

scientific article published on 5 September 2013

Potential Therapeutic Targets for Lung Repair During Human Ex Vivo Lung Perfusion

scientific article published on 17 March 2020

Pre-implantation multiple cytokine mRNA expression analysis of donor lung grafts predicts survival after lung transplantation in humans.

scientific article published in March 2006

Preparation of copper-containing bioactive glass/eggshell membrane nanocomposites for improving angiogenesis, antibacterial activity and wound healing

scientific article

Programming the cellular uptake of physiologically stable peptide-gold nanoparticle hybrids with single amino acids.

scientific article published on 21 September 2011

Progressive increase of CD4(+)/CD45RC(-) lymphocytes after allograft rat lung transplantation: a marker of acute rejection

scientific article published on 01 October 2002

Protective effects of long pentraxin PTX3 on lung injury in a severe acute respiratory syndrome model in mice.

scientific article published on 25 June 2012

Protein expression profiling predicts graft performance in clinical ex vivo lung perfusion.

scientific article published in March 2015

Protein kinase C mediates enterohemorrhagic Escherichia coli O157:H7-induced attaching and effacing lesions

scientific article published on 3 February 2014

Pulmonary bacterial communities in surgically resected noncystic fibrosis bronchiectasis lungs are similar to those in cystic fibrosis.

scientific article published on 8 February 2012

Raffinose improves the function of rat pulmonary grafts stored for twenty-four hours in low-potassium dextran solution

scientific article published on 01 March 2000

Rapid reperfusion causes stress failure in ischemic rat lungs

scientific article published in December 1998

Recipient T cells mediate reperfusion injury after lung transplantation in the rat

scientific article published on 01 November 2003

Reduction of tyrosine kinase activity and protein tyrosine dephosphorylation by anoxic stimulation in vitro.

scientific article published in January 1998

Regression of allograft airway fibrosis: the role of MMP-dependent tissue remodeling in obliterative bronchiolitis after lung transplantation

scientific article

Regulation of body length and bone mass by Gpr126/Adgrg6

scientific article published on 20 March 2020

Regulation of c-fos expression by static stretch in rat myometrial smooth muscle cells

scientific article published on 01 June 2002

Regulation of embryonic kidney branching morphogenesis and glomerular development by KISS1 receptor (Gpr54) through NFAT2- and Sp1-mediated Bmp7 expression.

scientific article

Regulation of hematopoietic-specific G-protein Galpha15 and Galpha16 by protein kinase C.

scientific article published in April 2003

Regulation of human prostate-specific G-protein coupled receptor, PSGR, by two distinct promoters and growth factors.

scientific article published in December 2005

Rejection of tracheal allograft by intrapulmonary lymphoid neogenesis in the absence of secondary lymphoid organs

scientific article published on 01 June 2012

Reperfusion-induced gene expression profiles in rat lung transplantation.

scientific article

Reprogramming immunosuppressive myeloid cells facilitates immunotherapy for colorectal cancer

scientific article published on 07 December 2020

Revealing the missing expressed genes beyond the human reference genome by RNA-Seq ⬇️

scientific article published on December 2, 2011

Roles of XB130, a novel adaptor protein, in cancer ⬇️

scientific article published on March 17, 2011

Safety and Efficacy of Ex Vivo Donor Lung Adenoviral IL-10 Gene Therapy in a Large Animal Lung Transplant Survival Model

scientific article published on 4 January 2017

Searching for acute respiratory distress syndrome genes: aren't we there yet?

scientific article published in February 2005

Self-assembling peptide-based nanoparticles enhance cellular delivery of the hydrophobic anticancer drug ellipticine through caveolae-dependent endocytosis

scientific article

Sevoflurane Attenuates Ischemia-Reperfusion Injury in a Rat Lung Transplantation Model.

scientific article published on 9 February 2017

Small molecule 1'-acetoxychavicol acetate suppresses breast tumor metastasis by regulating the SHP-1/STAT3/MMPs signaling pathway

scientific article published on 10 October 2014

Solid phase microextraction fills the gap in tissue sampling protocols.

scientific article

Solubility of Hydrophobic Compounds in Aqueous Solution Using Combinations of Self-assembling Peptide and Amino Acid

scientific article published on 20 September 2017

Soluble Adhesion Molecules During Ex Vivo Lung Perfusion Are Associated With Posttransplant Primary Graft Dysfunction

scientific article

Soluble platelet-endothelial cell adhesion molecule-1, a biomarker of ventilator-induced lung injury

scientific article

Spectrum of chronic lung allograft pathology in a mouse minor-mismatched orthotopic lung transplant model

scientific article published on 29 November 2018

Spleen Tyrosine Kinase Modulates Fibrous Airway Obliteration and Associated Lymphoid Neogenesis After Transplantation

scientific article published on 26 August 2015

Src protein tyrosine kinase family and acute inflammatory responses.

scientific article

Src tyrosine kinase inhibition prevents pulmonary ischemia-reperfusion-induced acute lung injury.

scientific article published on 17 February 2012

Stimulus-dependent dissociation between XB130 and Tks5 scaffold proteins promotes airway epithelial cell migration.

scientific article

Stretch-induced growth-promoting activities stimulate fetal rat lung epithelial cell proliferation

scientific article published on 01 July 1993

Stromal activation and formation of lymphoid-like stroma in chronic lung allograft dysfunction

scientific article published on 01 June 2011

Structure of the human P2Y₁₂ receptor in complex with an antithrombotic drug

scientific article published on 06 May 2014

Surfactant dysfunction develops when the immunized guinea-pig is challenged with ovalbumin aerosol

scientific article published on 01 November 1995

Synchronized changing of transinterface pressure, bubble radius and surface tension: a unique feature of lung surfactant ⬇️

scientific article published on September 24, 1997

Synthesis and Biological Evaluation of B-Cell Lymphoma 6 Inhibitors of N-Phenyl-4-pyrimidinamine Derivatives Bearing Potent Activities against Tumor Growth

scientific article published on 13 January 2020

Synthesis and biological evaluation of novel tetrahydro-β-carboline derivatives as antitumor growth and metastasis agents through inhibiting the transforming growth factor-β signaling pathway.

scientific article published on 27 January 2014

Systematical detection of significant genes in microarray data by incorporating gene interaction relationship in biological systems.

scientific article

TAT cell-penetrating peptide modulates inflammatory response and apoptosis in human lung epithelial cells.

scientific article published on June 2015

TLR-Activated Gap Junction Channels Protect Mice against Bacterial Infection through Extracellular UDP Release.

scientific article

TNFalpha-induced long pentraxin PTX3 expression in human lung epithelial cells via JNK.

scientific article

Targeted cell replacement with bone marrow cells for airway epithelial regeneration.

scientific article

Targeted deletion of the murine Lgr4 gene decreases lens epithelial cell resistance to oxidative stress and induces age-related cataract formation

scientific article published on 26 March 2015

Targeting the angiotensin system in posttransplant airway obliteration: the antifibrotic effect of angiotensin converting enzyme inhibition

scientific article published on 01 July 2000

Technique for prolonged normothermic ex vivo lung perfusion.

scientific article published in December 2008

The Blimp-1 gene regulatory region directs EGFP expression in multiple hematopoietic lineages and testis in mice

scientific article published on 19 September 2007

The actin-binding domain of actin filament-associated protein (AFAP) is involved in the regulation of cytoskeletal structure

scientific article published on 8 October 2011

The antiparasitic drug, potassium antimony tartrate, inhibits tumor angiogenesis and tumor growth in nonsmall-cell lung cancer

scientific article

The early responses of VEGF and its receptors during acute lung injury: implication of VEGF in alveolar epithelial cell survival.

scientific article published on January 2006

The effect of gender combinations on outcome in human lung transplantation: the International Society of Heart and Lung Transplantation Registry experience

scientific article published on 11 April 2006

The effect of mechanical strain on fetal rat lung cell proliferation: comparison of two- and three-dimensional culture systems

scientific article published on 01 December 1995

The effect of reflux and bile acid aspiration on the lung allograft and its surfactant and innate immunity molecules SP-A and SP-D

scientific article published on 01 August 2006

The greedy nature of mutant RAS: a boon for drug discovery targeting cancer metabolism?

scientific article

The potential of nanoscale combinations of self-assembling peptides and amino acids of the Src tyrosine kinase inhibitor in acute lung injury therapy

scientific article published on 3 March 2011

The prostate-specific G-protein coupled receptors PSGR and PSGR2 are prostate cancer biomarkers that are complementary to alpha-methylacyl-CoA racemase.

scientific article

The protein kinase C cascade regulates recruitment of matrix metalloprotease 9 to podosomes and its release and activation.

scientific article published on 11 October 2010

The role of intrapulmonary de novo lymphoid tissue in obliterative bronchiolitis after lung transplantation

scientific article

The role of the endothelin-1 pathway as a biomarker for donor lung assessment in clinical ex vivo lung perfusion.

scientific article published on 16 January 2015

The ubiquitination of rag A GTPase by RNF152 negatively regulates mTORC1 activation

scientific article

Therapeutic effects of inhaling aerosolized surfactant alone or with dexamethasone generated by a novel noninvasive apparatus on acute lung injury in rats

scientific article published on 01 November 2012

Toll-like receptor and cytokine gene expression in the early phase of human lung transplantation.

scientific article

Toll-like receptor-triggered calcium mobilization protects mice against bacterial infection through extracellular ATP release

scientific article

Total synthesis and biological studies of cryptocin and derivatives of equisetin and fusarisetin A.

scientific article published on October 2014

Towards Donor Lung Recovery - Gene Expression Changes During Ex Vivo Lung Perfusion of Human Lungs

scientific article published on 15 February 2018

Transbronchial administration of adenoviral-mediated interleukin-10 gene to the donor improves function in a pig lung transplant model.

scientific article

Transcriptional regulation of Tlr11 gene expression in epithelial cells.

scientific article published on 02 October 2009

Transcriptional signatures in donor lungs from donation after cardiac death vs after brain death: a functional pathway analysis.

scientific article published on 18 November 2010

Translational research: animal models of obliterative bronchiolitis after lung transplantation.

scientific article published on 06 August 2009

Transplant immunosuppression enhances efficiency of adenoviral-mediated gene retransfection: inhibition of interferon-gamma and immunoglobin G.

scientific article

Transplant immunosuppression increases and prolongs transgene expression following adenoviral-mediated transfection of rat lungs

scientific article published in October 2000

Transtracheal gene transfection of donor lungs prior to organ procurement increases transgene levels at reperfusion and following transplantation

article

Upregulation of T-helper 1 cytokines and chemokine expression in post-transplant airway obliteration

scientific article published on 01 June 1999

Upregulation of alveolar neutrophil enzymes and long pentraxin-3 in human chronic lung allograft dysfunction subtypes

scientific article published on 23 February 2018

Using the inherent chemistry of the endothelin-1 peptide to develop a rapid assay for pre-transplant donor lung assessment

scientific article published in December 2015

Usnic acid inhibits breast tumor angiogenesis and growth by suppressing VEGFR2-mediated AKT and ERK1/2 signaling pathways.

scientific article

Vascular endothelial growth factor and related molecules in acute lung injury.

scientific article published in November 2004

Ventilator-induced lung injury and mechanotransduction: why should we care?

scientific article published on January 2007

Ventilator-induced lung injury: role of protein-protein interaction in mechanosensation.

scientific article

XB130 Deficiency Causes Congenital Hypothyroidism in Mice due to Disorganized Apical Membrane Structure and Function of Thyrocytes

scientific article published in 2021

XB130 as an Independent Prognostic Factor in Human Esophageal Squamous Cell Carcinoma ⬇️

scientific article published on July 18, 2012

XB130 deficiency affects tracheal epithelial differentiation during airway repair

scientific article

XB130 deficiency enhances lipopolysaccharide-induced septic response and acute lung injury

scientific article published on 23 March 2016

XB130 mediates cancer cell proliferation and survival through multiple signaling events downstream of Akt.

scientific article

XB130 promotes bronchioalveolar stem cell and Club cell proliferation in airway epithelial repair and regeneration

scientific article published on 3 September 2015

XB130 translocation to microfilamentous structures mediates NNK-induced migration of human bronchial epithelial cells

scientific article published on 20 April 2015

XB130, a new adaptor protein, regulates expression of tumor suppressive microRNAs in cancer cells.

scientific article

XB130, a novel adaptor protein for signal transduction

scientific article

XB130, a novel adaptor protein, promotes thyroid tumor growth

scientific article

XB130, a tissue-specific adaptor protein that couples the RET/PTC oncogenic kinase to PI 3-kinase pathway.

scientific article

XB130-A Novel Adaptor Protein: Gene, Function, and Roles in Tumorigenesis

scientific article

XB130/Tks5 scaffold protein interaction regulates Src-mediated cell proliferation and survival

scientific article

ZNF383, a novel KRAB-containing zinc finger protein, suppresses MAPK signaling pathway.

scientific article published in August 2005

Zebrafish cancer and metastasis models for in vivo drug discovery

scientific article

α1-Anti-trypsin improves function of porcine donor lungs during ex-vivo lung perfusion.

scientific article published on 2 October 2017

α1-Antitrypsin inhibits ischemia reperfusion-induced lung injury by reducing inflammatory response and cell death.

scientific article published on 25 October 2013

β-Lapachone Induces NAD(P)H:Quinone Oxidoreductase-1- and Oxidative Stress-Dependent Heat Shock Protein 90 Cleavage and Inhibits Tumor Growth and Angiogenesis

scientific article published on 05 April 2016

δV1-1 Reduces Pulmonary Ischemia Reperfusion-Induced Lung Injury by Inhibiting Necrosis and Mitochondrial Localization of PKCδ and p53.

scientific article published on 14 September 2015

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