List of works - Ludek Blaha

A European Multi Lake Survey dataset of environmental variables, phytoplankton pigments and cyanotoxins

scientific article published on 23 October 2018

A European perspective on alternatives to animal testing for environmental hazard identification and risk assessment

scientific article

A novel approach for monitoring of cyanobacterial toxins: development and evaluation of the passive sampler for microcystins

article

Accumulation of Microcystins in Nile Tilapia, Oreochromis niloticus L., and Effects of a Complex Cyanobacterial Bloom on the Dietetic Quality of Muscles

Activation of Ah receptor by pure humic acids.

scientific article published on August 2006

Activation of the aryl hydrocarbon receptor by berberine in HepG2 and H4IIE cells: Biphasic effect on CYP1A1.

scientific article

Acute, chronic and reproductive toxicity of complex cyanobacterial blooms in Daphnia magna and the role of microcystins

scientific article published on 8 January 2014

Age dependency and mutual relations in T and B lymphocyte abnormalities in common variable immunodeficiency patients

scientific article published in February 2006

AhR-mediated and antiestrogenic activity of humic substances.

scientific article published on 16 January 2007

Altered Transcriptome Response in PBMCs of Czech Adults Linked to Multiple PFAS Exposure: B Cell Development as a Target of PFAS Immunotoxicity

scientific article published in 2023

Are in vitro methods for the detection of endocrine potentials in the aquatic environment predictive for in vivo effects? Outcomes of the Projects SchussenAktiv and SchussenAktivplus in the Lake Constance Area, Germany

scientific article (publication date: 2014)

Aryl hydrocarbon receptor-mediated and estrogenic activities of oxygenated polycyclic aromatic hydrocarbons and azaarenes originally identified in extracts of river sediments.

scientific article published in December 2001

Assessment of non-derivatized β-N-methylamino-l-alanine (BMAA) neurotoxin in free form in urine of patients with nonspecific neurological symptoms

scientific article published on 17 April 2017

Assessment of silver nanoparticle toxicity for common carp (Cyprinus carpio) fish embryos using a novel method controlling the agglomeration in the aquatic media.

scientific article published on 2 August 2015

Association of surface contamination by antineoplastic drugs with different working conditions in hospital pharmacies.

scientific article published in January 2014

Biological plausibility as a tool to associate analytical data for micropollutants and effect potentials in wastewater, surface water, and sediments with effects in fishes

scientific article

Bioluminescent Vibrio fischeri Assays in the Assessment of Seasonal and Spatial Patterns in Toxicity of Contaminated River Sediments

scientific article

Can cyanobacterial biomass applied to soil affect survival and reproduction of springtail Folsomia candida?

scientific article published on 22 December 2010

Can zero-valent iron nanoparticles remove waterborne estrogens?

scientific article published on 4 January 2015

Changes in concentrations of hydrophilic organic contaminants and of endocrine-disrupting potential downstream of small communities located adjacent to headwaters

scientific article

Comparison of 17 biotests for detection of cyanobacterial toxicity

article

Complex evaluation of ecotoxicity and genotoxicity of antimicrobials oxytetracycline and flumequine used in aquaculture.

scientific article published on 14 March 2011

Concentrations of microcystins in tissues of several fish species from freshwater reservoirs and ponds

scientific article published on 12 June 2013

Corrigendum to "Reduction of dioxin-like toxicity in effluents by additional wastewater treatment and related effects in fish" [Ecotoxicol. Environ. Saf. 132 (2016) 47-58].

scientific article

Critical assessment of the research outcomes of European birth cohorts: linking environmental factors with non-communicable diseases

scientific article

Cylindrospermopsin induces cellular stress and activation of ERK1/2 and p38 MAPK pathways in adult human liver stem cells

scientific article published on 22 March 2019

Cytotoxicity and aryl hydrocarbon receptor-mediated activity of n-heterocyclic polycyclic aromatic hydrocarbons: structure-activity relationships.

scientific article published on May 2006

Dioxins and dioxin-like compounds in composts and digestates from European countries as determined by the in vitro bioassay and chemical analysis

scientific article published on 15 December 2014

Do predictions from Species Sensitivity Distributions match with field data?

scientific article

Drinking water contaminants from epoxy resin-coated pipes: A field study.

scientific article published on 15 July 2016

EU-wide monitoring survey on emerging polar organic contaminants in wastewater treatment plant effluents

scientific article

EXPLORING THE NATURAL ROLE OF MICROCYSTINS-A REVIEW OF EFFECTS ON PHOTOAUTOTROPHIC ORGANISMS1

article

Ecotoxicity and genotoxicity assessment of cytostatic pharmaceuticals.

scientific article published in October 2007

Ecotoxicity and genotoxicity assessment of cytotoxic antineoplastic drugs and their metabolites

scientific article published on 10 July 2010

Effect of different cyanobacterial biomasses and their fractions with variable microcystin content on embryonal development of carp (Cyprinus carpio L.).

scientific article published on 14 January 2007

Effects of N-heterocyclic polyaromatic hydrocarbons on survival, reproduction, and biochemical parameters in Daphnia magna

scientific article published on 01 August 2006

Effects of cyanobacterial biomass and purified microcystins on malformations in Xenopus laevis: teratogenesis assay (FETAX).

scientific article published in December 2002

Effects of enrofloxacin, ciprofloxacin, and trimethoprim on two generations of Daphnia magna

Effects of microcystin and complex cyanobacterial samples on the growth and oxidative stress parameters in green alga Pseudokirchneriella subcapitata and comparison with the model oxidative stressor--herbicide paraquat

scientific article published in June 2010

Enantioselective effects of alpha-hexachlorocyclohexane (HCH) isomers on androgen receptor activity in vitro.

scientific article published on 2 October 2011

Endocrine effects of contaminated sediments on the freshwater snail Potamopyrgus antipodarum in vivo and in the cell bioassays in vitro.

scientific article

Environmental xenobiotics and nuclear receptors--interactions, effects and in vitro assessment.

scientific article

Estrogenic activity in extracts and exudates of cyanobacteria and green algae

scientific article published on 24 November 2011

Europe-wide survey of estrogenicity in wastewater treatment plant effluents: the need for the effect-based monitoring.

scientific article published on 30 May 2014

European demonstration program on the effect-based and chemical identification and monitoring of organic pollutants in European surface waters

scientific article published on 14 June 2017

Evaluation of extraction approaches linked to ELISA and HPLC for analyses of microcystin-LR, -RR and -YR in freshwater sediments with different organic material contents.

scientific article published on 8 July 2006

Evaluation of the Efficacy of Additional Measures Introduced for the Protection of Healthcare Personnel Handling Antineoplastic Drugs

article

Evaluation of the novel passive sampler for cyanobacterial toxins microcystins under various conditions including field sampling

scientific article published on 13 March 2010

Expert opinion on toxicity profiling--report from a NORMAN expert group meeting

scientific article

Immunomodulatory Potency of Microcystin, an Important Water-Polluting Cyanobacterial Toxin

scientific article published on 18 September 2015

Immunomodulatory effects of cyanobacterial toxin cylindrospermopsin on innate immune cells

scientific article published on 29 March 2019

Impact of PFAS exposure on prevalence of immune-mediated diseases in adults in the Czech Republic

scientific article published in 2023

In vitro assessment of sex steroids and related compounds in water and sediments - a critical review.

scientific article

In vitro modulation of intracellular receptor signaling and cytotoxicity induced by extracts of cyanobacteria, complex water blooms and their fractions ⬇️

scientific article published on August 9, 2011

In vivo effects of microcystins and complex cyanobacterial biomass on rats (Rattus norvegicus var. alba): changes in immunological and haematological parameters

scientific article published on 4 July 2013

Induction of aryl hydrocarbon receptor-mediated and estrogen receptor-mediated activities, and modulation of cell proliferation by dinaphthofurans.

scientific article published on September 2004

Inhibition of gap-junctional intercellular communication and activation of mitogen-activated protein kinases by cyanobacterial extracts--indications of novel tumor-promoting cyanotoxins?

scientific article published on 18 July 2009

Inhibitors of arachidonic acid metabolism potentiate tumour necrosis factor-alpha-induced apoptosis in HL-60 cells.

scientific article published in July 2001

Interference of contaminated sediment extracts and environmental pollutants with retinoid signaling.

scientific article published on August 2007

Isolation and endotoxin activities of lipopolysaccharides from cyanobacterial cultures and complex water blooms and comparison with the effects of heterotrophic bacteria and green alga

scientific article published in January 2008

Kinetic bacterial bioluminescence assay for contact sediment toxicity testing: relationships with the matrix composition and contamination.

scientific article published in March 2010

LC-MS analyses of microcystins in fish tissues overestimate toxin levels—critical comparison with LC-MS/MS

scientific article published on 10 June 2010

Metallothionein modulation in relation to cadmium bioaccumulation and age-dependent sensitivity of Chironomus riparius larvae

scientific article published on 9 March 2016

Mixtures of chemical pollutants at European legislation safety concentrations: how safe are they?

scientific article

Modulation of gap-junctional intercellular communication by a series of cyanobacterial samples from nature and laboratory cultures.

scientific article published on 18 May 2011

Multiple stressors for the environment: Present and future challenges and perspectives

Novel metabolites in cyanobacterium Cylindrospermopsis raciborskii with potencies to inhibit gap junctional intercellular communication.

scientific article published on 16 September 2013

Oxidative stress and detoxification biomarker responses in aquatic freshwater vertebrates exposed to microcystins and cyanobacterial biomass ⬇️

scientific article published on 06 July 2012

POCIS sampling in combination with ELISA: Screening of sulfonamide residues in surface and waste waters ⬇️

scientific article published on November 17, 2011

Pan-European survey on the occurrence of selected polar organic persistent pollutants in ground water

scientific article published in June 2010

Phytoestrogens and sterols in waters with cyanobacterial blooms - Analytical methods and estrogenic potencies

scientific article published on 5 December 2016

Phytoestrogens in milk: Overestimations caused by contamination of the hydrolytic enzyme used during sample extraction

scientific article published on 6 July 2016

Rapid in situ toxicity testing with luminescent bacteria Photorhabdus luminescens and Vibrio fischeri adapted to a small portable luminometer.

scientific article published on 26 November 2016

Reduction of dioxin-like toxicity in effluents by additional wastewater treatment and related effects in fish

scientific article published on 2 June 2016

Removal of microcystins by phototrophic biofilms. A microcosm study.

scientific article

SchussenAktivplus: reduction of micropollutants and of potentially pathogenic bacteria for further water quality improvement of the river Schussen, a tributary of Lake Constance, Germany

article

Selected endocrine disrupting compounds (vinclozolin, flutamide, ketoconazole and dicofol): effects on survival, occurrence of males, growth, molting and reproduction of Daphnia magna.

scientific article published in May 2008

Separation of microcystins by capillary electrochromatography in monolithic columns

scientific article published on 16 June 2006

Simultaneous determination of reduced and oxidized glutathione in tissues by a novel liquid chromatography-mass spectrometry method: application in an inhalation study of Cd nanoparticles.

scientific article published on 29 July 2014

TOXIC EFFECTS AND OXIDATIVE STRESS IN HIGHER PLANTS EXPOSED TO POLYCYCLIC AROMATIC HYDROCARBONS AND THEIR N-HETEROCYCLIC DERIVATIVES

article

Temperature Effects Explain Continental Scale Distribution of Cyanobacterial Toxins.

scientific article published on 13 April 2018

Teratogenic effects of five anticancer drugs on Xenopus laevis embryos

scientific article published on 13 July 2016

Teratogenicity and Embryotoxicity in Aquatic Organisms After Pesticide Exposure and the Role of Oxidative Stress ⬇️

scientific article published on January 1, 2011

The effects of PAHs and N-PAHs on retinoid signaling and Oct-4 expression in vitro ⬇️

scientific article published on November 25, 2010

The first occurrence of the cyanobacterial alkaloid toxin cylindrospermopsin in the Czech Republic as determined by immunochemical and LC/MS methods.

scientific article

The isolation and characterization of lipopolysaccharides from Microcystis aeruginosa, a prominent toxic water bloom forming cyanobacteria

scientific article published on 16 October 2013

Toxic effects of metals on two euryhaline ciliate species adapted to variable salinities

Toxicity and modulations of biomarkers inXenopus laevis embryos exposed to polycyclic aromatic hydrocarbons and theirN-heterocyclic derivatives

article

Toxicity of hydroxylated and quinoid PCB metabolites: inhibition of gap junctional intercellular communication and activation of aryl hydrocarbon and estrogen receptors in hepatic and mammary cells.

scientific article published on March 2004

Toxins produced in cyanobacterial water blooms - toxicity and risks

scientific article

Tumor promoting effects of cyanobacterial extracts are potentiated by anthropogenic contaminants--evidence from in vitro study.

scientific article published on 8 May 2012

Tumor promoting properties of a cigarette smoke prevalent polycyclic aromatic hydrocarbon as indicated by the inhibition of gap junctional intercellular communication via phosphatidylcholine-specific phospholipase C.

scientific article

Utilization of the solid sorbent media in monitoring of airborne cyclophosphamide concentrations and the implications for occupational hygiene

scientific article published on 6 April 2011

Validation of the species sensitivity distribution in retrospective risk assessment of herbicides at the river basin scale-the Scheldt river basin case study

scientific article published on 27 March 2013

Wastewater canal Vojlovica, industrial complex Pančevo, Serbia: Preliminary ecotoxicological assessment of contaminated sediment

article by Ivana Planojevic et al published 2011 in Journal of the Serbian Chemical Society

Web portal for management of bioindication methods and ecotoxicological tests in ecological risk assessment

scientific article published on 17 October 2006

What level of estrogenic activity determined by in vitro assays in municipal waste waters can be considered as safe?

scientific article published on 31 December 2013

Yeast Biosensors for Detection of Environmental Pollutants: Current State and Limitations

scientific article published on 11 February 2016

List of works by Ludek Blaha

A European Multi Lake Survey dataset of environmental variables, phytoplankton pigments and cyanotoxins

A European perspective on alternatives to animal testing for environmental hazard identification and risk assessment

A novel approach for monitoring of cyanobacterial toxins: development and evaluation of the passive sampler for microcystins

Accumulation of Microcystins in Nile Tilapia, Oreochromis niloticus L., and Effects of a Complex Cyanobacterial Bloom on the Dietetic Quality of Muscles

Activation of Ah receptor by pure humic acids.

Activation of the aryl hydrocarbon receptor by berberine in HepG2 and H4IIE cells: Biphasic effect on CYP1A1.

Acute, chronic and reproductive toxicity of complex cyanobacterial blooms in Daphnia magna and the role of microcystins

Age dependency and mutual relations in T and B lymphocyte abnormalities in common variable immunodeficiency patients

AhR-mediated and antiestrogenic activity of humic substances.

Altered Transcriptome Response in PBMCs of Czech Adults Linked to Multiple PFAS Exposure: B Cell Development as a Target of PFAS Immunotoxicity

Are in vitro methods for the detection of endocrine potentials in the aquatic environment predictive for in vivo effects? Outcomes of the Projects SchussenAktiv and SchussenAktivplus in the Lake Constance Area, Germany

Aryl hydrocarbon receptor-mediated and estrogenic activities of oxygenated polycyclic aromatic hydrocarbons and azaarenes originally identified in extracts of river sediments.

Assessment of non-derivatized β-N-methylamino-l-alanine (BMAA) neurotoxin in free form in urine of patients with nonspecific neurological symptoms

Assessment of silver nanoparticle toxicity for common carp (Cyprinus carpio) fish embryos using a novel method controlling the agglomeration in the aquatic media.

Association of surface contamination by antineoplastic drugs with different working conditions in hospital pharmacies.

Biological plausibility as a tool to associate analytical data for micropollutants and effect potentials in wastewater, surface water, and sediments with effects in fishes

Bioluminescent Vibrio fischeri Assays in the Assessment of Seasonal and Spatial Patterns in Toxicity of Contaminated River Sediments

Can cyanobacterial biomass applied to soil affect survival and reproduction of springtail Folsomia candida?

Can zero-valent iron nanoparticles remove waterborne estrogens?

Changes in concentrations of hydrophilic organic contaminants and of endocrine-disrupting potential downstream of small communities located adjacent to headwaters

Comparison of 17 biotests for detection of cyanobacterial toxicity

Complex evaluation of ecotoxicity and genotoxicity of antimicrobials oxytetracycline and flumequine used in aquaculture.

Concentrations of microcystins in tissues of several fish species from freshwater reservoirs and ponds

Corrigendum to "Reduction of dioxin-like toxicity in effluents by additional wastewater treatment and related effects in fish" [Ecotoxicol. Environ. Saf. 132 (2016) 47-58].

Critical assessment of the research outcomes of European birth cohorts: linking environmental factors with non-communicable diseases

Cylindrospermopsin induces cellular stress and activation of ERK1/2 and p38 MAPK pathways in adult human liver stem cells

Cytotoxicity and aryl hydrocarbon receptor-mediated activity of n-heterocyclic polycyclic aromatic hydrocarbons: structure-activity relationships.

Dioxins and dioxin-like compounds in composts and digestates from European countries as determined by the in vitro bioassay and chemical analysis

Do predictions from Species Sensitivity Distributions match with field data?

Drinking water contaminants from epoxy resin-coated pipes: A field study.

EU-wide monitoring survey on emerging polar organic contaminants in wastewater treatment plant effluents

EXPLORING THE NATURAL ROLE OF MICROCYSTINS-A REVIEW OF EFFECTS ON PHOTOAUTOTROPHIC ORGANISMS1

Ecotoxicity and genotoxicity assessment of cytostatic pharmaceuticals.

Ecotoxicity and genotoxicity assessment of cytotoxic antineoplastic drugs and their metabolites

Effect of different cyanobacterial biomasses and their fractions with variable microcystin content on embryonal development of carp (Cyprinus carpio L.).

Effects of N-heterocyclic polyaromatic hydrocarbons on survival, reproduction, and biochemical parameters in Daphnia magna

Effects of cyanobacterial biomass and purified microcystins on malformations in Xenopus laevis: teratogenesis assay (FETAX).

Effects of enrofloxacin, ciprofloxacin, and trimethoprim on two generations of Daphnia magna

Effects of microcystin and complex cyanobacterial samples on the growth and oxidative stress parameters in green alga Pseudokirchneriella subcapitata and comparison with the model oxidative stressor--herbicide paraquat

Enantioselective effects of alpha-hexachlorocyclohexane (HCH) isomers on androgen receptor activity in vitro.

Endocrine effects of contaminated sediments on the freshwater snail Potamopyrgus antipodarum in vivo and in the cell bioassays in vitro.

Environmental xenobiotics and nuclear receptors--interactions, effects and in vitro assessment.

Estrogenic activity in extracts and exudates of cyanobacteria and green algae

Europe-wide survey of estrogenicity in wastewater treatment plant effluents: the need for the effect-based monitoring.

European demonstration program on the effect-based and chemical identification and monitoring of organic pollutants in European surface waters

Evaluation of extraction approaches linked to ELISA and HPLC for analyses of microcystin-LR, -RR and -YR in freshwater sediments with different organic material contents.

Evaluation of the Efficacy of Additional Measures Introduced for the Protection of Healthcare Personnel Handling Antineoplastic Drugs

Evaluation of the novel passive sampler for cyanobacterial toxins microcystins under various conditions including field sampling

Expert opinion on toxicity profiling--report from a NORMAN expert group meeting

Immunomodulatory Potency of Microcystin, an Important Water-Polluting Cyanobacterial Toxin

Immunomodulatory effects of cyanobacterial toxin cylindrospermopsin on innate immune cells

Impact of PFAS exposure on prevalence of immune-mediated diseases in adults in the Czech Republic

In vitro assessment of sex steroids and related compounds in water and sediments - a critical review.

In vitro modulation of intracellular receptor signaling and cytotoxicity induced by extracts of cyanobacteria, complex water blooms and their fractions ⬇️

In vivo effects of microcystins and complex cyanobacterial biomass on rats (Rattus norvegicus var. alba): changes in immunological and haematological parameters

Induction of aryl hydrocarbon receptor-mediated and estrogen receptor-mediated activities, and modulation of cell proliferation by dinaphthofurans.

Inhibition of gap-junctional intercellular communication and activation of mitogen-activated protein kinases by cyanobacterial extracts--indications of novel tumor-promoting cyanotoxins?

Inhibitors of arachidonic acid metabolism potentiate tumour necrosis factor-alpha-induced apoptosis in HL-60 cells.

Interference of contaminated sediment extracts and environmental pollutants with retinoid signaling.

Isolation and endotoxin activities of lipopolysaccharides from cyanobacterial cultures and complex water blooms and comparison with the effects of heterotrophic bacteria and green alga

Kinetic bacterial bioluminescence assay for contact sediment toxicity testing: relationships with the matrix composition and contamination.

LC-MS analyses of microcystins in fish tissues overestimate toxin levels—critical comparison with LC-MS/MS

Metallothionein modulation in relation to cadmium bioaccumulation and age-dependent sensitivity of Chironomus riparius larvae

Mixtures of chemical pollutants at European legislation safety concentrations: how safe are they?

Modulation of gap-junctional intercellular communication by a series of cyanobacterial samples from nature and laboratory cultures.

Multiple stressors for the environment: Present and future challenges and perspectives

Multiple stressors for the environment: Present and future challenges and perspectives

Novel metabolites in cyanobacterium Cylindrospermopsis raciborskii with potencies to inhibit gap junctional intercellular communication.

Oxidative stress and detoxification biomarker responses in aquatic freshwater vertebrates exposed to microcystins and cyanobacterial biomass ⬇️

POCIS sampling in combination with ELISA: Screening of sulfonamide residues in surface and waste waters ⬇️

Pan-European survey on the occurrence of selected polar organic persistent pollutants in ground water

Phytoestrogens and sterols in waters with cyanobacterial blooms - Analytical methods and estrogenic potencies

Phytoestrogens in milk: Overestimations caused by contamination of the hydrolytic enzyme used during sample extraction

Rapid in situ toxicity testing with luminescent bacteria Photorhabdus luminescens and Vibrio fischeri adapted to a small portable luminometer.

Reduction of dioxin-like toxicity in effluents by additional wastewater treatment and related effects in fish

Removal of microcystins by phototrophic biofilms. A microcosm study.

SchussenAktivplus: reduction of micropollutants and of potentially pathogenic bacteria for further water quality improvement of the river Schussen, a tributary of Lake Constance, Germany

Selected endocrine disrupting compounds (vinclozolin, flutamide, ketoconazole and dicofol): effects on survival, occurrence of males, growth, molting and reproduction of Daphnia magna.

Separation of microcystins by capillary electrochromatography in monolithic columns