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List of works by Raúl Padrón

18O labeling on Ser45 but not on Ser35 supports the cooperative phosphorylation mechanism on tarantula thick filament activation

scientific article published on 23 January 2020

A method for 3D-reconstruction of a muscle thick filament using the tilt series images of a single filament electron tomogram

scientific article

A molecular model of phosphorylation-based activation and potentiation of tarantula muscle thick filaments

scientific article

A new model for the surface arrangement of myosin molecules in tarantula thick filaments

scientific article published on 01 April 2000

An invertebrate smooth muscle with striated muscle myosin filaments

scientific article

Atomic model of a myosin filament in the relaxed state

scientific article published on August 2005

Blebbistatin stabilizes the helical order of myosin filaments by promoting the switch 2 closed state.

scientific article

Conserved Intramolecular Interactions Maintain Myosin Interacting-Heads Motifs Explaining Tarantula Muscle Super-Relaxed State Structural Basis

scientific article published on 2 February 2016

Cryo-EM structure of the inhibited (10S) form of myosin II

scientific article published on 02 December 2020

Different head environments in tarantula thick filaments support a cooperative activation process.

scientific article

Direct visualization of myosin filament symmetry in tarantula striated muscle by electron microscopy

scientific article published on 01 July 1993

Direct visualization of myosin-binding protein C bridging myosin and actin filaments in intact muscle.

scientific article

Effects of myosin variants on interacting-heads motif explain distinct hypertrophic and dilated cardiomyopathy phenotypes.

scientific article published on 13 June 2017

Helical order in tarantula thick filaments requires the "closed" conformation of the myosin head.

scientific article published in September 2004

Heterogeneity of Z-band structure within a single muscle sarcomere: implications for sarcomere assembly

scientific article published on 01 September 2003

Interacting-heads motif has been conserved as a mechanism of myosin II inhibition since before the origin of animals

scientific article published on 14 February 2018

Lessons from a tarantula: new insights into muscle thick filament and myosin interacting-heads motif structure and function.

scientific article published on 4 September 2017

Lessons from a tarantula: new insights into myosin interacting-heads motif evolution and its implications on disease

scientific article

Matching structural densities from different biophysical origins with gain and bias.

scientific article published on 18 September 2010

Mechanism of phosphorylation of the regulatory light chain of myosin from tarantula striated muscle.

scientific article

Myosin Sequestration Regulates Sarcomere Function, Cardiomyocyte Energetics, and Metabolism, Informing the Pathogenesis of Hypertrophic Cardiomyopathy

scientific article published on 27 January 2020

Purification of native myosin filaments from muscle.

scientific article

Sequential myosin phosphorylation activates tarantula thick filament via a disorder-order transition.

scientific article published in July 2015

Structure of the myosin filaments of relaxed and rigor vertebrate striated muscle studied by rapid freezing electron microscopy

scientific article published on 01 November 1992

Tarantula myosin free head regulatory light chain phosphorylation stiffens N-terminal extension, releasing it and blocking its docking back

scientific article published in July 2015

The effect of the ATP analogue AMPPNP on the structure of crossbridges in vertebrate skeletal muscles: X-ray diffraction and mechanical studies

scientific article published on 01 December 1984

The myosin interacting-heads motif is present in the relaxed thick filament of the striated muscle of scorpion ⬇️

scientific article published on September 7, 2012

The myosin interacting-heads motif present in live tarantula muscle explains tetanic and posttetanic phosphorylation mechanisms

scientific article published on 22 May 2020

Three-Dimensional Reconstruction of Tarantula Myosin Filaments Suggests How Phosphorylation May Regulate Myosin Activity

scientific article

Three-dimensional reconstruction of thick filaments from rapidly frozen, freeze-substituted tarantula muscle

scientific article published on 01 November 1995

Understanding the organisation and role of myosin binding protein C in normal striated muscle by comparison with MyBP-C knockout cardiac muscle

scientific article

Visualization of myosin helices in sections of rapidly frozen relaxed tarantula muscle

scientific article published on 01 May 1992

X-ray diffraction study of the structural changes accompanying phosphorylation of tarantula muscle

scientific article published on 01 June 1991

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