List of works - Elin Lehrmann

A genetically engineered ovarian cancer mouse model based on fallopian tube transformation mimics human high-grade serous carcinoma development.

scientific article

ATM regulates a DNA damage response posttranscriptional RNA operon in lymphocytes

scientific article

Absence of cannabinoid 1 receptor in beta cells protects against high-fat/high-sugar diet-induced beta cell dysfunction and inflammation in murine islets

scientific article published in March 2018

Altered Extracellular Vesicle Concentration, Cargo, and Function in Diabetes

scientific article published on 02 May 2018

Altered gene expression in pulmonary tissue of tryptophan hydroxylase-1 knockout mice: implications for pulmonary arterial hypertension

scientific article

Altered learning, memory, and social behavior in type 1 taste receptor subunit 3 knock-out mice are associated with neuronal dysfunction

scientific article published on 18 May 2017

Amitriptyline-mediated cognitive enhancement in aged 3×Tg Alzheimer's disease mice is associated with neurogenesis and neurotrophic activity

scientific article

Blast traumatic brain injury-induced cognitive deficits are attenuated by preinjury or postinjury treatment with the glucagon-like peptide-1 receptor agonist, exendin-4.

scientific article

CORRIGENDUM: SRT1720 improves survival and healthspan of obese mice.

scientific article published on 16 January 2013

CREB phosphorylation regulates striatal transcriptional responses in the self-administration model of methamphetamine addiction in the rat.

scientific article published on 30 May 2013

Cognitive Impairments Induced by Concussive Mild Traumatic Brain Injury in Mouse Are Ameliorated by Treatment with Phenserine via Multiple Non-Cholinergic and Cholinergic Mechanisms

scientific article

Cytokines in cerebral ischemia: expression of transforming growth factor beta-1 (TGF-beta 1) mRNA in the postischemic adult rat hippocampus

scientific article published on 01 January 1995

Delineation of a conserved arrestin-biased signaling repertoire in vivo.

scientific article

Distinct inhibitory effects on mTOR signaling by ethanol and INK128 in diffuse large B-cell lymphoma.

scientific article

Down-regulation of eIF4GII by miR-520c-3p represses diffuse large B cell lymphoma development.

scientific article published on 30 January 2014

Eda-activated RelB recruits an SWI/SNF (BAF) chromatin-remodeling complex and initiates gene transcription in skin appendage formation

scientific article published on 23 July 2018

Elongator and codon bias regulate protein levels in mammalian peripheral neurons

scientific article published in March 2018

Enhanced upregulation of CRH mRNA expression in the nucleus accumbens of male rats after a second injection of methamphetamine given thirty days later

scientific article

Evidence for miR-181 involvement in neuroinflammatory responses of astrocytes

scientific article

Exendin-4, a glucagon-like peptide-1 receptor agonist prevents mTBI-induced changes in hippocampus gene expression and memory deficits in mice

scientific article

Experience Modulates the Effects of Histone Deacetylase Inhibitors on Gene and Protein Expression in the Hippocampus: Impaired Plasticity in Aging.

scientific article

FACS purification of immunolabeled cell types from adult rat brain.

scientific article published on 3 September 2011

Focal cerebral ischemia induces increased myelin basic protein and growth-associated protein-43 gene transcription in peri-infarct areas in the rat brain

scientific article published on 01 June 2001

GIT2 Acts as a Systems-Level Coordinator of Neurometabolic Activity and Pathophysiological Aging.

scientific article

Gene expression profiling reveals distinct cocaine-responsive genes in human fetal CNS cell types.

scientific article

Genome-wide profiling identifies a subset of methamphetamine (METH)-induced genes associated with METH-induced increased H4K5Ac binding in the rat striatum.

scientific article

Genomic deletion of GIT2 induces a premature age-related thymic dysfunction and systemic immune system disruption

scientific article

Global dissociation of HuR-mRNA complexes promotes cell survival after ionizing radiation

scientific article

Hepatitis C virus upregulates B-cell receptor signaling: a novel mechanism for HCV-associated B-cell lymphoproliferative disorders

scientific article published on 5 October 2015

Hydroxyurea attenuates oxidative, metabolic, and excitotoxic stress in rat hippocampal neurons and improves spatial memory in a mouse model of Alzheimer's disease

scientific article published on 29 August 2018

Immunohistochemical visualization of newly formed quinolinate in the normal and excitotoxically lesioned rat striatum.

scientific article published in December 2001

LncRNA OIP5-AS1/cyrano suppresses GAK expression to control mitosis

scientific article published on 19 April 2017

Loss of miR-451a enhances SPARC production during myogenesis

MNKs act as a regulatory switch for eIF4E1 and eIF4E3 driven mRNA translation in DLBCL.

scientific article

Metabolic and molecular framework for the enhancement of endurance by intermittent food deprivation.

scientific article published on 27 February 2018

Methamphetamine preconditioning causes differential changes in striatal transcriptional responses to large doses of the drug.

scientific article

MicroRNAs Modulate Oxidative Stress in Hypertension through PARP-1 Regulation

scientific article

Microarray analysis of oxidative stress regulated genes in mesencephalic dopaminergic neuronal cells: relevance to oxidative damage in Parkinson's disease

scientific journal article

Microglia and macrophages are major sources of locally produced transforming growth factor-beta1 after transient middle cerebral artery occlusion in rats.

scientific article published in December 1998

Microglial and macrophage reactions mark progressive changes and define the penumbra in the rat neocortex and striatum after transient middle cerebral artery occlusion

scientific article published on September 29, 1997

Mild traumatic brain injury-induced hippocampal gene expressions: The identification of target cellular processes for drug development.

scientific article published on 08 February 2016

Muscle cannabinoid 1 receptor regulates Il-6 and myostatin expression, governing physical performance and whole-body metabolism

scientific article published on 06 February 2019

Novel RNA-binding activity of MYF5 enhances Ccnd1/Cyclin D1 mRNA translation during myogenesis

scientific article published on 26 January 2016

Novel RNA-binding activity of NQO1 promotes SERPINA1 mRNA translation

scientific article published on 8 August 2016

Platelets contribute to the pathogenesis of experimental autoimmune encephalomyelitis

scientific article

Regulation of HuR structure and function by dihydrotanshinone-I.

scientific article

SRT1720 improves survival and healthspan of obese mice

scientific article

Serum extracellular vesicle depletion processes affect release and infectivity of HIV-1 in culture

scientific article

Skeletal muscle ex vivo mitochondrial respiration parallels decline in vivo oxidative capacity, cardiorespiratory fitness, and muscle strength: The Baltimore Longitudinal Study of Aging.

scientific article published on 21 January 2018

The association between poverty and gene expression within peripheral blood mononuclear cells in a diverse Baltimore City cohort

scientific article published on 24 September 2020

Tomatidine enhances lifespan and healthspan in C. elegans through mitophagy induction via the SKN-1/Nrf2 pathway

scientific article

Topoisomerase 3β interacts with RNAi machinery to promote heterochromatin formation and transcriptional silencing in Drosophila

scientific article published in Nature Communications

Transcriptional changes common to human cocaine, cannabis and phencyclidine abuse

scientific article

Transcriptional correlates of human substance use.

scientific article published on October 2008

Transcriptome States Reflect Imaging of Aging States

scientific article published on 5 December 2017

Wnt5A promotes an adaptive, senescent-like stress response, while continuing to drive invasion in melanoma cells

scientific article

sFRP2 in the aged microenvironment drives melanoma metastasis and therapy resistance

scientific article published on 4 April 2016

List of works by Elin Lehrmann

A genetically engineered ovarian cancer mouse model based on fallopian tube transformation mimics human high-grade serous carcinoma development.

ATM regulates a DNA damage response posttranscriptional RNA operon in lymphocytes

Absence of cannabinoid 1 receptor in beta cells protects against high-fat/high-sugar diet-induced beta cell dysfunction and inflammation in murine islets

Altered Extracellular Vesicle Concentration, Cargo, and Function in Diabetes

Altered gene expression in pulmonary tissue of tryptophan hydroxylase-1 knockout mice: implications for pulmonary arterial hypertension

Altered learning, memory, and social behavior in type 1 taste receptor subunit 3 knock-out mice are associated with neuronal dysfunction

Amitriptyline-mediated cognitive enhancement in aged 3×Tg Alzheimer's disease mice is associated with neurogenesis and neurotrophic activity

Blast traumatic brain injury-induced cognitive deficits are attenuated by preinjury or postinjury treatment with the glucagon-like peptide-1 receptor agonist, exendin-4.

CORRIGENDUM: SRT1720 improves survival and healthspan of obese mice.

CREB phosphorylation regulates striatal transcriptional responses in the self-administration model of methamphetamine addiction in the rat.

Cognitive Impairments Induced by Concussive Mild Traumatic Brain Injury in Mouse Are Ameliorated by Treatment with Phenserine via Multiple Non-Cholinergic and Cholinergic Mechanisms

Cytokines in cerebral ischemia: expression of transforming growth factor beta-1 (TGF-beta 1) mRNA in the postischemic adult rat hippocampus

Delineation of a conserved arrestin-biased signaling repertoire in vivo.

Distinct inhibitory effects on mTOR signaling by ethanol and INK128 in diffuse large B-cell lymphoma.

Down-regulation of eIF4GII by miR-520c-3p represses diffuse large B cell lymphoma development.

Eda-activated RelB recruits an SWI/SNF (BAF) chromatin-remodeling complex and initiates gene transcription in skin appendage formation

Elongator and codon bias regulate protein levels in mammalian peripheral neurons

Enhanced upregulation of CRH mRNA expression in the nucleus accumbens of male rats after a second injection of methamphetamine given thirty days later

Evidence for miR-181 involvement in neuroinflammatory responses of astrocytes

Exendin-4, a glucagon-like peptide-1 receptor agonist prevents mTBI-induced changes in hippocampus gene expression and memory deficits in mice

Experience Modulates the Effects of Histone Deacetylase Inhibitors on Gene and Protein Expression in the Hippocampus: Impaired Plasticity in Aging.

FACS purification of immunolabeled cell types from adult rat brain.

Focal cerebral ischemia induces increased myelin basic protein and growth-associated protein-43 gene transcription in peri-infarct areas in the rat brain

GIT2 Acts as a Systems-Level Coordinator of Neurometabolic Activity and Pathophysiological Aging.

Gene expression profiling reveals distinct cocaine-responsive genes in human fetal CNS cell types.

Genome-wide profiling identifies a subset of methamphetamine (METH)-induced genes associated with METH-induced increased H4K5Ac binding in the rat striatum.

Genomic deletion of GIT2 induces a premature age-related thymic dysfunction and systemic immune system disruption

Global dissociation of HuR-mRNA complexes promotes cell survival after ionizing radiation

Hepatitis C virus upregulates B-cell receptor signaling: a novel mechanism for HCV-associated B-cell lymphoproliferative disorders

Hydroxyurea attenuates oxidative, metabolic, and excitotoxic stress in rat hippocampal neurons and improves spatial memory in a mouse model of Alzheimer's disease

Immunohistochemical visualization of newly formed quinolinate in the normal and excitotoxically lesioned rat striatum.

LncRNA OIP5-AS1/cyrano suppresses GAK expression to control mitosis

Loss of miR-451a enhances SPARC production during myogenesis

MNKs act as a regulatory switch for eIF4E1 and eIF4E3 driven mRNA translation in DLBCL.

Metabolic and molecular framework for the enhancement of endurance by intermittent food deprivation.

Methamphetamine preconditioning causes differential changes in striatal transcriptional responses to large doses of the drug.

MicroRNAs Modulate Oxidative Stress in Hypertension through PARP-1 Regulation

Microarray analysis of oxidative stress regulated genes in mesencephalic dopaminergic neuronal cells: relevance to oxidative damage in Parkinson's disease

Microglia and macrophages are major sources of locally produced transforming growth factor-beta1 after transient middle cerebral artery occlusion in rats.

Microglial and macrophage reactions mark progressive changes and define the penumbra in the rat neocortex and striatum after transient middle cerebral artery occlusion

Mild traumatic brain injury-induced hippocampal gene expressions: The identification of target cellular processes for drug development.

Muscle cannabinoid 1 receptor regulates Il-6 and myostatin expression, governing physical performance and whole-body metabolism

Novel RNA-binding activity of MYF5 enhances Ccnd1/Cyclin D1 mRNA translation during myogenesis

Novel RNA-binding activity of NQO1 promotes SERPINA1 mRNA translation

Platelets contribute to the pathogenesis of experimental autoimmune encephalomyelitis

Regulation of HuR structure and function by dihydrotanshinone-I.

SRT1720 improves survival and healthspan of obese mice

Serum extracellular vesicle depletion processes affect release and infectivity of HIV-1 in culture

Skeletal muscle ex vivo mitochondrial respiration parallels decline in vivo oxidative capacity, cardiorespiratory fitness, and muscle strength: The Baltimore Longitudinal Study of Aging.

The association between poverty and gene expression within peripheral blood mononuclear cells in a diverse Baltimore City cohort

Tomatidine enhances lifespan and healthspan in C. elegans through mitophagy induction via the SKN-1/Nrf2 pathway

Topoisomerase 3β interacts with RNAi machinery to promote heterochromatin formation and transcriptional silencing in Drosophila

Transcriptional changes common to human cocaine, cannabis and phencyclidine abuse

Transcriptional correlates of human substance use.

Transcriptome States Reflect Imaging of Aging States

Wnt5A promotes an adaptive, senescent-like stress response, while continuing to drive invasion in melanoma cells

sFRP2 in the aged microenvironment drives melanoma metastasis and therapy resistance