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List of works by Patrik Onnerfjord

A flow immunoassay for studies of human exposure and toxicity in biological samples

scientific article published on 01 January 1998

A missense mutation in the aggrecan C-type lectin domain disrupts extracellular matrix interactions and causes dominant familial osteochondritis dissecans

scientific article

Age-related changes in the proteoglycans of human skin. Specific cleavage of decorin to yield a major catabolic fragment in adult skin

scientific article

Altered osteoclast development and function in osteopontin deficient mice

scientific article

Analysis of "old" proteins unmasks dynamic gradient of cartilage turnover in human limbs

scientific article published on 09 October 2019

Association between changes in molecular biomarkers of cartilage matrix turnover and changes in knee articular cartilage: a longitudinal pilot study

scientific article published on 03 May 2019

Binding mitochondria to cryogel monoliths allows detection of proteins specifically released following permeability transition.

scientific article

Biomarkers and proteomic analysis of osteoarthritis

scientific article published on 30 August 2014

Calbindin D28k Exhibits Properties Characteristic of a Ca2+ Sensor

scientific article published in Journal of Biological Chemistry

Cartilage matrix remodelling differs by disease state and joint type

scientific article published on 24 August 2017

Cartilage oligomeric matrix protein neoepitope in the synovial fluid of horses with acute lameness: A new biomarker for the early stages of osteoarthritis.

scientific article published on 17 January 2017

Changes in proteasome structure and function caused by HAMLET in tumor cells.

scientific article

Chondroadherin fragmentation mediated by the protease HTRA1 distinguishes human intervertebral disc degeneration from normal aging

scientific article published on 14 May 2013

Chondrocytes Derived From Mesenchymal Stromal Cells and Induced Pluripotent Cells of Patients With Familial Osteochondritis Dissecans Exhibit an Endoplasmic Reticulum Stress Response and Defective Matrix Assembly.

scientific article published on 7 July 2016

Cleavage of fibromodulin in cartilage explants involves removal of the N-terminal tyrosine sulfate-rich region by proteolysis at a site that is sensitive to matrix metalloproteinase-13.

scientific article published on 3 December 2003

Connective tissue growth factor contributes to joint homeostasis and osteoarthritis severity by controlling the matrix sequestration and activation of latent TGFβ

scientific article published on 20 June 2018

Correction: The Skeletal Phenotype of Chondroadherin Deficient Mice.

scientific article

Development of a Cartilage Oligomeric Matrix Protein Neo-Epitope Assay for the Detection of Intra-Thecal Tendon Disease

scientific article published on 20 March 2020

Down-regulation of human extracellular cysteine protease inhibitors by the secreted staphylococcal cysteine proteases, staphopain A and B.

scientific article published in April 2007

Elucidating the Molecular Composition of Cartilage by Proteomics. ⬇️

scientific article published on 03 December 2015

Fluorescence polarisation for immunoreagent characterisation

scientific article published in April 1998

Fragmentation of proteins in cartilage treated with interleukin-1: specific cleavage of type IX collagen by matrix metalloproteinase 13 releases the NC4 domain

scientific article published on 19 October 2007

High sample throughput flow immunoassay utilising restricted access columns for the separation of bound and free label

scientific article published on 01 March 1998

Homogeneous sample preparation for automated high throughput analysis with matrix-assisted laser desorption/ionisation time-of-flight mass spectrometry

scientific article

Identification and characterization of asporin. a novel member of the leucine-rich repeat protein family closely related to decorin and biglycan

scientific article (publication date: 13 April 2001)

Identification of tyrosine sulfation in extracellular leucine-rich repeat proteins using mass spectrometry

scientific article published on 8 October 2003

Integrated microanalytical technology enabling rapid and automated protein identification

scientific article

Interactions of histidine-rich glycoprotein with immunoglobulins and proteins of the complement system.

scientific article

Interleukin-1 receptor antagonist (IL-1Ra) is more effective in suppressing cytokine-induced catabolism in cartilage-synovium co-culture than in cartilage monoculture

scientific article published on 13 November 2019

Link N is cleaved by human annulus fibrosus cells generating a fragment with retained biological activity

scientific article published on 23 May 2014

Mining the Proteome Associated with Rheumatic and Autoimmune Diseases

scientific article published on 23 October 2019

Mutant huntingtin interacts with {beta}-tubulin and disrupts vesicular transport and insulin secretion

scientific article

Nanomechanical phenotype of chondroadherin-null murine articular cartilage.

scientific article published on 2 June 2014

Novel cartilage oligomeric matrix protein (COMP) neoepitopes identified in synovial fluids from patients with joint diseases using affinity chromatography and mass spectrometry.

scientific article

OARSI Clinical Trials Recommendations: Soluble biomarker assessments in clinical trials in osteoarthritis.

scientific article

Osteopontin Expression in Small Airway Epithelium in Copd is Dependent on Differentiation and Confined to Subsets of Cells

scientific article published on 29 October 2019

Picoliter sample preparation in MALDI-TOF MS using a micromachined silicon flow-through dispenser

scientific article published on November 1998

Prevention of domain swapping inhibits dimerization and amyloid fibril formation of cystatin C: use of engineered disulfide bridges, antibodies, and carboxymethylpapain to stabilize the monomeric form of cystatin C.

scientific article published on 17 March 2004

Protein identification platform utilizing micro dispensing technology interfaced to matrix-assisted laser desorption ionization time-of-flight mass spectrometry

scientific article published in July 2000

Proteomic analysis of tendon extracellular matrix reveals disease stage-specific fragmentation and differential cleavage of COMP (cartilage oligomeric matrix protein).

scientific article published on 07 January 2014

Proteomic analysis of the LPS-induced stress response in rat chondrocytes reveals induction of innate immune response components in articular cartilage

scientific journal article

Proteomic characterization of the normal human medial meniscus body using data-independent acquisition mass spectrometry

scientific article published on 28 January 2020

Proteomics Profiling of Human Synovial Fluid Suggests Increased Protein Interplay in Early-Osteoarthritis (OA) That Is Lost in Late-Stage OA

scientific article published on 21 January 2022

Quantification of cartilage oligomeric matrix protein (COMP) and a COMP neoepitope in synovial fluid of patients with different joint disorders by novel automated assays

scientific article published in May 2017

Quantitative proteomics analysis of cartilage response to mechanical injury and cytokine treatment.

scientific article published on 14 December 2016

Quantitative proteomics at different depths in human articular cartilage reveals unique patterns of protein distribution

scientific article published on 01 September 2014

Signal amplification using "spot-on-a-chip" technology for the identification of proteins via MALDI-TOF MS.

scientific article

Targeted proteomics of hip articular cartilage in OA and fracture patients

scientific article published on 04 January 2019

The C-terminal domain of chondroadherin: a new regulator of osteoclast motility counteracting bone loss

scientific article published in August 2014

The C-terminal peptide of chondroadherin modulates cellular activity by selectively binding to heparan sulfate chains.

scientific article published on 21 November 2012

The Tyrosine Sulfate Domain of Fibromodulin Binds Collagen and Enhances Fibril Formation

scientific article

The extracellular matrix and inflammation: fibromodulin activates the classical pathway of complement by directly binding C1q.

scientific article published on 26 July 2005

The minor collagens in articular cartilage

scientific article published on 17 February 2017

The novel small leucine-rich protein chondroadherin-like (CHADL) is expressed in cartilage and modulates chondrocyte differentiation

scientific article

The role of cartilage glycosaminoglycan structure in gagCEST

scientific article published on 30 January 2020

The tyrosine sulfate-rich domains of the LRR proteins fibromodulin and osteoadherin bind motifs of basic clusters in a variety of heparin-binding proteins, including bioactive factors.

scientific article published on 21 August 2009

The α2β1 binding domain of chondroadherin inhibits breast cancer-induced bone metastases and impairs primary tumour growth: a preclinical study

scientific article published on 18 December 2014

Three-dimensional microstructure of human meniscus posterior horn in health and osteoarthritis

scientific article published on 10 July 2019

Ucma, a novel secreted cartilage-specific protein with implications in osteogenesis

scientific journal article

Ultra-high field magnetic resonance imaging parameter mapping in the posterior horn of ex vivo human menisci

scientific article published on 12 December 2018

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