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List of works by Malcolm D. McLeod

A high yielding synthesis of anthranilate esters from sterically hindered alcohols

scientific article published in February 2001

A review of designer anabolic steroids in equine sports

scientific article published on 12 October 2016

A simple method for the small scale synthesis and solid-phase extraction purification of steroid sulfates

scientific article

AE Succinimide, an Analogue of Methyllycaconitine, When Bound Generates a Nonconducting Conformation of the α4β2 Nicotinic Acetylcholine Receptor

scientific article published on 14 January 2020

Analysis of anabolic steroids in the horse: development of a generic ELISA for the screening of 17alpha-alkyl anabolic steroid metabolites

scientific article published in August 2005

Application of a Double Mannich Reaction UsingBis(aminol) Ethers in the Synthesis of AE Ring Analogues of Methyl Lycaconitine

scientific article published in 2004

Application of olefin metathesis to the synthesis of ABE ring analogues of methyllycaconitine

scientific article published in August 2002

C-Glycosylation of Oxygenated Naphthols with 3-Dimethylamino-2,3,6-trideoxy-L-arabino-hexopyranose and 3-Azido-2,3,6-trideoxy-D-arabino-hexopyranose

scientific article published in 2003

Constant Ion Loss Method for the Untargeted Detection of Bis-sulfate Metabolites

scientific article

Covalent attachment of antagonists to the α7 nicotinic acetylcholine receptor: synthesis and reactivity of substituted maleimides

scientific article published on 25 May 2012

Covalent trapping of methyllycaconitine at the α4-α4 interface of the α4β2 nicotinic acetylcholine receptor: antagonist binding site and mode of receptor inhibition revealed.

scientific article published on 26 July 2013

Detection and metabolic investigations of a novel designer steroid: 3-chloro-17α-methyl-5α-androstan-17β-ol.

scientific article published on 23 June 2015

Diastereoselective osmium-catalyzed vicinal oxyamination of acyclic allylic alcohol derivatives

scientific article published on 01 November 2014

Double-Mannich annulation of cyclic ketones using N,N-Bis(ethoxymethyl)alkylamine reagents

scientific article published on 01 July 2006

Enantioselective total synthesis of (-)-dactylolide

scientific article published on 01 March 2006

Enhancing the Steroid Sulfatase Activity of the Arylsulfatase from Pseudomonas aeruginosa

Epiandrosterone sulfate prolongs the detectability of testosterone, 4-androstenedione, and dihydrotestosterone misuse by means of carbon isotope ratio mass spectrometry.

scientific article published on 24 August 2017

Escherichia coli glucuronylsynthase: an engineered enzyme for the synthesis of beta-glucuronides.

scientific article

Experimental and kinetic studies of the Escherichia coli glucuronylsynthase: an engineered enzyme for the synthesis of glucuronide conjugates

scientific article published on 24 February 2011

In vivo and in vitro metabolism of the designer anabolic steroid furazadrol in thoroughbred racehorses.

scientific article published on 26 February 2016

In vivo metabolism of the designer anabolic steroid hemapolin in the thoroughbred horse

scientific article published on 16 January 2020

Metabolism of stanozolol: chemical synthesis and identification of a major canine urinary metabolite by liquid chromatography-electrospray ionisation ion trap mass spectrometry.

scientific article published on 11 September 2009

Methyllycaconitine analogues have mixed antagonist effects at nicotinic acetylcholine receptors

scientific article published in July 2005

Osmium-catalyzed vicinal oxyamination of alkenes by N-(4-toluenesulfonyloxy)carbamates

scientific article published on 24 September 2012

Photochemical behavior and Na+,K+-ATPase sensitivity of voltage-sensitive styrylpyridinium fluorescent membrane probes

scientific article published in March 2006

Presence of multiple binding sites on α9α10 nAChR receptors alludes to stoichiometric-dependent action of the α-conotoxin, Vc1.1.

scientific article published on 15 February 2014

Profiling Urinary Sulfate Metabolites With Mass Spectrometry

scientific article published on 23 February 2022

Pseudomonas aeruginosa arylsulfatase: a purified enzyme for the mild hydrolysis of steroid sulfates.

scientific article published on 5 March 2015

Replacing PAPS: In vitro phase II sulfation of steroids with the liver S9 fraction employing ATP and sodium sulfate

scientific article published on 21 June 2017

Selective manipulation of steroid hydroxyl groups with boronate esters: Efficient access to antigenic C-3 linked steroid-protein conjugates and steroid sulfate standards for drug detection

scientific article published on 22 September 2006

Steroid sulfation pathways targeted by disulfates determination. Application to prenatal diagnosis.

scientific article published on 19 February 2018

Structure-activity relationships of synthetic progestins in a yeast-based in vitro androgen bioassay

scientific article

Synthesis and Radiolabelling of Ipratropium and Tiotropium for Use as PET Ligands in the Study of Inhaled Drug Deposition

Synthesis of (±)-Panduratin A and Related Natural Products Using the High Pressure Diels-Alder Reaction

scientific article published in January 2013

Synthesis of 3-azido-2,3,6-trideoxy-beta-D-arabino-hexopyranosyl pyranonaphthoquinone analogues of medermycin

scientific article published in May 2003

Synthesis of 3α,6β‐Dihydroxyandrostan‐17‐one 3‐Glucuronides for the Detection of Testosterone Misuse

Synthesis of simple analogues of methyllycaconitine—an efficient method for the preparation of the N-substituted anthranilate pharmacophore

scientific article published in July 2004

Synthesis of steroid bisglucuronide and sulfate glucuronide reference materials: Unearthing neglected treasures of steroid metabolism

scientific article published on 01 December 2018

Synthesis of the beta-hydroxydopa-gamma-hydroxy-delta-sulfinylnorvaline component of ustiloxins A and B.

scientific article published on 3 February 2005

Synthesis of tricyclic analogues of methyllycaconitine using ring closing metathesis to append a B ring to an AE azabicyclic fragment

scientific article published on 10 May 2004

The Escherichia coli glucuronylsynthase promoted synthesis of steroid glucuronides: improved practicality and broader scope

scientific article

The Sharpless asymmetric aminohydroxylation reaction: optimising ligand/substrate control of regioselectivity for the synthesis of 3- and 4-aminosugars

scientific article published on 07 May 2008

The Total Synthesis of (–)-Tetrahydrolipstatin

The enantioselective synthesis of APTO and AETD: polyhydroxylated beta-amino acid constituents of the microsclerodermin cyclic peptides

scientific article published on 17 August 2007

The metabolism of anabolic-androgenic steroids in the greyhound.

scientific article

The use of tandem yeast and mammalian cell in vitro androgen bioassays to detect androgens in internet-sourced sport supplements.

scientific article published on 27 June 2016

Total Synthesis of (+)-Concanamycin F We thank the EPSRC (GR/K54052), Knoll Pharmaceuticals (CASE Studentship to V.A.D.), the Cambridge Commonwealth Trust (M.D.M.), and Merck for support, and Dr R. Norrie (Knoll Pharmaceuticals) for helpful discussi

scientific article published on 01 April 2000

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