List of works - Thomas Kislinger

A Genome Scale Screen for Mutants with Delayed Exit from Mitosis: Ire1-Independent Induction of Autophagy Integrates ER Homeostasis into Mitotic Lifespan

scientific article

A Proteome Resource of Ovarian Cancer Ascites: Integrated Proteomic and Bioinformatic Analyses To Identify Putative Biomarkers

A combination of H2A.Z and H4 acetylation recruits Brd2 to chromatin during transcriptional activation

scientific article

A live zebrafish-based screening system for human nuclear receptor ligand and cofactor discovery

scientific article

A novel community driven software for functional enrichment analysis of extracellular vesicles data.

scientific article

A proteomic investigation of isogenic radiation resistant prostate cancer cell lines

scientific article published on 30 June 2021

Advanced Glycation End Products Activate Endothelium Through Signal-Transduction Receptor RAGE

scientific article published on 01 February 2002

Advances in ovarian cancer proteomics: the quest for biomarkers and improved therapeutic interventions.

scientific article published on August 2008

An acetylated form of histone H2A.Z regulates chromosome architecture in Schizosaccharomyces pombe

scientific article published on 15 November 2009

Analysis of extracellular vesicles: new avenues for signaling biology and biomarker discovery.

scientific article published in May 2013

Analysis of protein glycation products by MALDI-TOF/MS.

scientific article published in June 2005

Automated 2D peptide separation on a 1D nano-LC-MS system

scientific article published on 01 March 2009

Barbiturate Induced Benzophenanthridine Alkaloid Formation Proceeds by Gene Transcript Accumulation in the California Poppy ⬇️

scientific article published on December 18, 1997

Bioinformatic analysis of membrane and associated proteins in murine cardiomyocytes and human myocardium

scientific article published on 01 December 2020

Blockade of RAGE–amphoterin signalling suppresses tumour growth and metastases

scientific article published in Nature

Blockade of receptor for advanced glycation end-products restores effective wound healing in diabetic mice.

scientific article published on August 2001

CHCHD2 Is Coamplified with EGFR in NSCLC and Regulates Mitochondrial Function and Cell Migration.

scientific article

Cardiovascular proteomics: tools to develop novel biomarkers and potential applications

scientific article published on 17 October 2006

Cell-surface proteomics for the identification of novel therapeutic targets in cancer.

scientific article published on 18 January 2018

Cell-surface proteomics identifies lineage-specific markers of embryo-derived stem cells

scientific article published on 15 March 2012

Characterization of Protein Content Present in Exosomes Isolated from Conditioned Media and Urine

scientific article published on 2 February 2017

Characterization of the proteins released from activated platelets leads to localization of novel platelet proteins in human atherosclerotic lesions

scientific article published on 20 November 2003

Choice of biological source material supersedes oxidative stress in its influence on DJ-1 in vivo interactions with Hsp90.

scientific article published on 26 August 2011

Clinical proteomics: getting to the heart of the matter

scientific article published on 01 June 2012

Comparative proteomics profiling of a phospholamban mutant mouse model of dilated cardiomyopathy reveals progressive intracellular stress responses

scientific article

Comparative systems biology of human and mouse as a tool to guide the modeling of human placental pathology

scientific article published on 16 June 2009

Constitutively active calcineurin induces cardiac endoplasmic reticulum stress and protects against apoptosis that is mediated by α-crystallin-B ⬇️

scientific article published on October 11, 2010

Detecting protein variants by mass spectrometry: a comprehensive study in cancer cell-lines

scientific article

Divergent evolution of temozolomide resistance in glioblastoma stem cells is reflected in extracellular vesicles and coupled with radiosensitization

scientific article published on 28 July 2017

EVpedia: a community web portal for extracellular vesicles research

scientific article

Ectopic miR-125a Expression Induces Long-Term Repopulating Stem Cell Capacity in Mouse and Human Hematopoietic Progenitors

scientific article

Endoplasmic reticulum protein targeting of phospholamban: a common role for an N-terminal di-arginine motif in ER retention?

scientific article

Evolutionarily conserved intercalated disc protein Tmem65 regulates cardiac conduction and connexin 43 function

scientific article

Expansion of stem cells counteracts age-related mammary regression in compound Timp1/Timp3 null mice.

scientific article published on 23 February 2015

Extracellular vesicles in ovarian cancer: applications to tumor biology, immunotherapy and biomarker discovery

scientific article published on 12 March 2016

Functionally selective activation of the dopamine receptor D<sub>2</sub> is mirrored by the protein expression profiles

scientific article published on 10 February 2021

Genes, proteins and complexes: the multifaceted nature of FHL family proteins in diverse tissues ⬇️

scientific article published on December 1, 2010

Genome-wide analysis of the maternal-to-zygotic transition in Drosophila primordial germ cells

scientific article published on 20 February 2012

Genome-wide germline correlates of the epigenetic landscape of prostate cancer

scientific article published on 07 October 2019

Global proteome analysis identifies active immunoproteasome subunits in human platelets

scientific article published on 21 August 2014

Global survey of organ and organelle protein expression in mouse: combined proteomic and transcriptomic profiling

scientific journal article

Glomulin: a permissivity factor for vaccinia virus infection.

scientific article published on 26 January 2012

Glycoprotein 2 is a specific cell surface marker of human pancreatic progenitors.

scientific article published on 24 August 2017

Glycoproteomics Identifies Plexin-B3 as a Targetable Cell Surface Protein Required for the Growth and Invasion of Triple-Negative Breast Cancer Cells

scientific article published in 2022

HLA-DP84Gly constitutively presents endogenous peptides generated by the class I antigen processing pathway

scientific article published on 10 May 2017

High-throughput approaches for precision medicine in high-grade serous ovarian cancer

scientific article published on 09 October 2020

Hotspot activating PRKD1 somatic mutations in polymorphous low-grade adenocarcinomas of the salivary glands.

scientific article

Identification of a BET family bromodomain/casein kinase II/TAF-containing complex as a regulator of mitotic condensin function

scientific article published on 22 February 2014

Identification of an FHL1 protein complex containing ACTN1, ACTN4, and PDLIM1 using affinity purifications and MS-based protein-protein interaction analysis

scientific article published on 18 January 2011

Identification of differentially expressed proteins in direct expressed prostatic secretions of men with organ-confined versus extracapsular prostate cancer

scientific article

Identification of novel ryanodine receptor 1 (RyR1) protein interaction with calcium homeostasis endoplasmic reticulum protein (CHERP)

scientific article

Identification of pathways associated with invasive behavior by ovarian cancer cells using multidimensional protein identification technology (MudPIT).

scientific article

In-depth proteomic analyses of direct expressed prostatic secretions

scientific article

In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine

scientific article

In-depth proteomic analyses of ovarian cancer cell line exosomes reveals differential enrichment of functional categories compared to the NCI 60 proteome

scientific article published on 14 January 2014

In-depth proteomics of ovarian cancer ascites: combining shotgun proteomics and selected reaction monitoring mass spectrometry.

scientific article

Integrated Omic analysis of lung cancer reveals metabolism proteome signatures with prognostic impact

scientific article published in Nature Communications

Integrated omic analysis of oropharyngeal carcinomas reveals human papillomavirus (HPV)-dependent regulation of the activator protein 1 (AP-1) pathway

scientific article

Integrated proteomic and transcriptomic profiling of mouse lung development and Nmyc target genes

scientific article published on 08 May 2007

Integrating gene and protein expression data: pattern analysis and profile mining

scientific article

Isolation of cell surface proteins for mass spectrometry-based proteomics

scientific article published on 01 February 2010

Loss of the Timp gene family is sufficient for the acquisition of the CAF-like cell state

scientific article published on 24 August 2014

Mammary molecular portraits reveal lineage-specific features and progenitor cell vulnerabilities

scientific article published on 19 June 2018

Mass spectrometry-based proteomics: a useful tool for biomarker discovery?

scientific article published on 19 March 2008

Metalloprotease inhibitor TIMP proteins control FGF-2 bioavailability and regulate skeletal growth

scientific article published on 01 August 2019

MicroRNA networks in mouse lung organogenesis

scientific article

Minimal information for studies of extracellular vesicles 2018 (MISEV2018): a position statement of the International Society for Extracellular Vesicles and update of the MISEV2014 guidelines

scientific article published on 23 November 2018

Molecular heterogeneity of non-small cell lung carcinoma patient-derived xenografts closely reflect their primary tumors

scientific article published on 17 October 2016

Multidimensional protein identification technology analysis highlights mitoxantrone-induced expression modulations in the primary prostate cancer cell proteome

scientific article published on March 2009

N(epsilon)-(carboxymethyl)lysine adducts of proteins are ligands for receptor for advanced glycation end products that activate cell signaling pathways and modulate gene expression

scientific journal article

N-Glycoproteomics of Patient-Derived Xenografts: A Strategy to Discover Tumor-Associated Proteins in High-Grade Serous Ovarian Cancer

scientific article published on 10 April 2019

Novel approaches for the identification of biomarkers of aggressive prostate cancer

scientific article published on 28 June 2013

Novel insights into head and neck cancer using next-generation "omic" technologies

scientific article

Onco-proteogenomics: cancer proteomics joins forces with genomics

scientific article

Optimization of small extracellular vesicle isolation from expressed prostatic secretions in urine for in-depth proteomic analysis

scientific article published on 01 February 2022

Organelle resolved proteomics uncovers PLA2R1 as a novel cell surface marker required for chordoma growth

scientific article published in 2024

PRISM, a generic large scale proteomic investigation strategy for mammals

scientific article published on 10 February 2003

PTP1B controls non-mitochondrial oxygen consumption by regulating RNF213 to promote tumour survival during hypoxia

scientific article published on 20 June 2016

Peptide separations by on-line MudPIT compared to isoelectric focusing in an off-gel format: application to a membrane-enriched fraction from C2C12 mouse skeletal muscle cells.

scientific article published on October 2009

Potentially novel candidate biomarkers for head and neck squamous cell carcinoma identified using an integrated cell line-based discovery strategy

scientific article

Primary tumor xenografts of human lung adeno and squamous cell carcinoma express distinct proteomic signatures.

scientific article

Proteogenomics: Opportunities and Caveats

scientific article published on 27 January 2016

Proteome analysis of mouse model systems: A tool to model human disease and for the investigation of tissue-specific biology.

scientific article published on 15 May 2010

Proteomic Analysis of Cancer Associated Fibroblasts Reveal a Paracrine Role for MFAP5 in Human Oral Tongue Squamous Cell Carcinoma

scientific article published on 22 April 2018

Proteomic Profiling of Secreted Proteins, Exosomes, and Microvesicles in Cell Culture Conditioned Media.

scientific article published in January 2018

Proteomic Response of Human Umbilical Vein Endothelial Cells to Histamine Stimulation.

scientific article published on 18 September 2017

Proteomic analysis of human fetal atria and ventricle

scientific article published on 31 October 2014

Proteomic profiles of human lung adeno and squamous cell carcinoma using super-SILAC and label-free quantification approaches

scientific article published on March 2014

Proteomic profiling of the planarian Schmidtea mediterranea and its mucous reveals similarities with human secretions and those predicted for parasitic flatworms

scientific article

Proteomics‐based investigations of animal models of disease ⬇️

scientific article published on May 1, 2008

Proteotranscriptomic Analysis Reveals Stage Specific Changes in the Molecular Landscape of Clear-Cell Renal Cell Carcinoma

scientific article

Qualitative changes in the proteome of extracellular vesicles accompanying cancer cell transition to mesenchymal state.

scientific article published on 13 August 2013

Quantitative Proteomics of Intestinal Mucosa From Male Mice Lacking Intestinal Epithelial Insulin Receptors

scientific article published on 7 June 2017

Quantitative peptide and protein profiling by mass spectrometry

scientific article published in January 2009

RAGE blockade stabilizes established atherosclerosis in diabetic apolipoprotein E-null mice.

scientific article

REEP5 depletion causes sarco-endoplasmic reticulum vacuolization and cardiac functional defects

scientific article published on 19 February 2020

Recent advances in mass spectrometry based clinical proteomics: applications to cancer research

scientific article published on 24 May 2020

Receptor for advanced glycation end products mediates inflammation and enhanced expression of tissue factor in vasculature of diabetic apolipoprotein E-null mice.

scientific article published in June 2001

Relative quantification of N(epsilon)-(Carboxymethyl)lysine, imidazolone A, and the Amadori product in glycated lysozyme by MALDI-TOF mass spectrometry.

scientific article published in January 2003

Reporters to mark and eliminate basal or luminal epithelial cells in culture and in vivo

scientific article published on 20 June 2018

Semi-supervised Learning Predicts Approximately One Third of the Alternative Splicing Isoforms as Functional Proteins

scientific article

Serum proteomic analysis of a pre-symptomatic multiple sclerosis cohort

scientific article published on 7 August 2014

Standardization and harmonization of distributed multi-center proteotype analysis supporting precision medicine studies

scientific article published on 16 October 2020

System-level analysis of neuroblastoma tumor-initiating cells implicates AURKB as a novel drug target for neuroblastoma.

scientific article

Targeted proteomics by selected reaction monitoring mass spectrometry: applications to systems biology and biomarker discovery ⬇️

scientific article published on October 25, 2010

Targeted proteomics identifies liquid-biopsy signatures for extracapsular prostate cancer

scientific article published on 28 June 2016

The E3 ligase PIRH2 polyubiquitylates CHK2 and regulates its turnover

scientific article

The Glc7 phosphatase subunit of the cleavage and polyadenylation factor is essential for transcription termination on snoRNA genes.

scientific article published in March 2008

The Proteogenomic Landscape of Curable Prostate Cancer

scientific article published on 01 March 2019

The emerging role of extracellular vesicles as biomarkers for urogenital cancers.

scientific article

The proteomics of prostate cancer exosomes

scientific article published on 25 February 2014

Translational analysis of mouse and human placental protein and mRNA reveals distinct molecular pathologies in human preeclampsia

scientific article published on 10 October 2011

Tumor-derived exosomes and microvesicles in head and neck cancer: implications for tumor biology and biomarker discovery

scientific article published on May 2013

Use of colloidal silica-beads for the isolation of cell-surface proteins for mass spectrometry-based proteomics

scientific article

Using proteomics to probe neurons.

scientific article published on 2 July 2015

VennDIS: a JavaFX-based Venn and Euler diagram software to generate publication quality figures

scientific article published on 23 January 2015

List of works by Thomas Kislinger

A Genome Scale Screen for Mutants with Delayed Exit from Mitosis: Ire1-Independent Induction of Autophagy Integrates ER Homeostasis into Mitotic Lifespan

A Proteome Resource of Ovarian Cancer Ascites: Integrated Proteomic and Bioinformatic Analyses To Identify Putative Biomarkers

A combination of H2A.Z and H4 acetylation recruits Brd2 to chromatin during transcriptional activation

A live zebrafish-based screening system for human nuclear receptor ligand and cofactor discovery

A novel community driven software for functional enrichment analysis of extracellular vesicles data.

A proteomic investigation of isogenic radiation resistant prostate cancer cell lines

Advanced Glycation End Products Activate Endothelium Through Signal-Transduction Receptor RAGE

Advances in ovarian cancer proteomics: the quest for biomarkers and improved therapeutic interventions.

An acetylated form of histone H2A.Z regulates chromosome architecture in Schizosaccharomyces pombe

Analysis of extracellular vesicles: new avenues for signaling biology and biomarker discovery.

Analysis of protein glycation products by MALDI-TOF/MS.

Automated 2D peptide separation on a 1D nano-LC-MS system

Barbiturate Induced Benzophenanthridine Alkaloid Formation Proceeds by Gene Transcript Accumulation in the California Poppy ⬇️

Bioinformatic analysis of membrane and associated proteins in murine cardiomyocytes and human myocardium

Blockade of RAGE–amphoterin signalling suppresses tumour growth and metastases

Blockade of receptor for advanced glycation end-products restores effective wound healing in diabetic mice.

CHCHD2 Is Coamplified with EGFR in NSCLC and Regulates Mitochondrial Function and Cell Migration.

Cardiovascular proteomics: tools to develop novel biomarkers and potential applications

Cell-surface proteomics for the identification of novel therapeutic targets in cancer.

Cell-surface proteomics identifies lineage-specific markers of embryo-derived stem cells

Characterization of Protein Content Present in Exosomes Isolated from Conditioned Media and Urine

Characterization of the proteins released from activated platelets leads to localization of novel platelet proteins in human atherosclerotic lesions

Choice of biological source material supersedes oxidative stress in its influence on DJ-1 in vivo interactions with Hsp90.

Clinical proteomics: getting to the heart of the matter

Comparative proteomics profiling of a phospholamban mutant mouse model of dilated cardiomyopathy reveals progressive intracellular stress responses

Comparative systems biology of human and mouse as a tool to guide the modeling of human placental pathology

Constitutively active calcineurin induces cardiac endoplasmic reticulum stress and protects against apoptosis that is mediated by α-crystallin-B ⬇️

Detecting protein variants by mass spectrometry: a comprehensive study in cancer cell-lines

Divergent evolution of temozolomide resistance in glioblastoma stem cells is reflected in extracellular vesicles and coupled with radiosensitization

EVpedia: a community web portal for extracellular vesicles research

Ectopic miR-125a Expression Induces Long-Term Repopulating Stem Cell Capacity in Mouse and Human Hematopoietic Progenitors

Endoplasmic reticulum protein targeting of phospholamban: a common role for an N-terminal di-arginine motif in ER retention?

Evolutionarily conserved intercalated disc protein Tmem65 regulates cardiac conduction and connexin 43 function

Expansion of stem cells counteracts age-related mammary regression in compound Timp1/Timp3 null mice.

Extracellular vesicles in ovarian cancer: applications to tumor biology, immunotherapy and biomarker discovery

Functionally selective activation of the dopamine receptor D<sub>2</sub> is mirrored by the protein expression profiles

Genes, proteins and complexes: the multifaceted nature of FHL family proteins in diverse tissues ⬇️

Genome-wide analysis of the maternal-to-zygotic transition in Drosophila primordial germ cells

Genome-wide germline correlates of the epigenetic landscape of prostate cancer

Global proteome analysis identifies active immunoproteasome subunits in human platelets

Global survey of organ and organelle protein expression in mouse: combined proteomic and transcriptomic profiling

Glomulin: a permissivity factor for vaccinia virus infection.

Glycoprotein 2 is a specific cell surface marker of human pancreatic progenitors.

Glycoproteomics Identifies Plexin-B3 as a Targetable Cell Surface Protein Required for the Growth and Invasion of Triple-Negative Breast Cancer Cells

HLA-DP84Gly constitutively presents endogenous peptides generated by the class I antigen processing pathway

High-throughput approaches for precision medicine in high-grade serous ovarian cancer

Hotspot activating PRKD1 somatic mutations in polymorphous low-grade adenocarcinomas of the salivary glands.

Identification of a BET family bromodomain/casein kinase II/TAF-containing complex as a regulator of mitotic condensin function

Identification of an FHL1 protein complex containing ACTN1, ACTN4, and PDLIM1 using affinity purifications and MS-based protein-protein interaction analysis

Identification of differentially expressed proteins in direct expressed prostatic secretions of men with organ-confined versus extracapsular prostate cancer

Identification of novel ryanodine receptor 1 (RyR1) protein interaction with calcium homeostasis endoplasmic reticulum protein (CHERP)

Identification of pathways associated with invasive behavior by ovarian cancer cells using multidimensional protein identification technology (MudPIT).

In-depth proteomic analyses of direct expressed prostatic secretions

In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine

In-depth proteomic analyses of ovarian cancer cell line exosomes reveals differential enrichment of functional categories compared to the NCI 60 proteome

In-depth proteomics of ovarian cancer ascites: combining shotgun proteomics and selected reaction monitoring mass spectrometry.

Integrated Omic analysis of lung cancer reveals metabolism proteome signatures with prognostic impact

Integrated omic analysis of oropharyngeal carcinomas reveals human papillomavirus (HPV)-dependent regulation of the activator protein 1 (AP-1) pathway

Integrated proteomic and transcriptomic profiling of mouse lung development and Nmyc target genes

Integrating gene and protein expression data: pattern analysis and profile mining

Isolation of cell surface proteins for mass spectrometry-based proteomics

Loss of the Timp gene family is sufficient for the acquisition of the CAF-like cell state

Mammary molecular portraits reveal lineage-specific features and progenitor cell vulnerabilities

Mass spectrometry-based proteomics: a useful tool for biomarker discovery?

Metalloprotease inhibitor TIMP proteins control FGF-2 bioavailability and regulate skeletal growth

MicroRNA networks in mouse lung organogenesis

Minimal information for studies of extracellular vesicles 2018 (MISEV2018): a position statement of the International Society for Extracellular Vesicles and update of the MISEV2014 guidelines

Molecular heterogeneity of non-small cell lung carcinoma patient-derived xenografts closely reflect their primary tumors

Multidimensional protein identification technology analysis highlights mitoxantrone-induced expression modulations in the primary prostate cancer cell proteome

N(epsilon)-(carboxymethyl)lysine adducts of proteins are ligands for receptor for advanced glycation end products that activate cell signaling pathways and modulate gene expression

N-Glycoproteomics of Patient-Derived Xenografts: A Strategy to Discover Tumor-Associated Proteins in High-Grade Serous Ovarian Cancer

Novel approaches for the identification of biomarkers of aggressive prostate cancer

Novel insights into head and neck cancer using next-generation "omic" technologies

Onco-proteogenomics: cancer proteomics joins forces with genomics

Optimization of small extracellular vesicle isolation from expressed prostatic secretions in urine for in-depth proteomic analysis

Organelle resolved proteomics uncovers PLA2R1 as a novel cell surface marker required for chordoma growth

PRISM, a generic large scale proteomic investigation strategy for mammals

PTP1B controls non-mitochondrial oxygen consumption by regulating RNF213 to promote tumour survival during hypoxia

Peptide separations by on-line MudPIT compared to isoelectric focusing in an off-gel format: application to a membrane-enriched fraction from C2C12 mouse skeletal muscle cells.