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List of works by Isao Okazaki

A case of subacute hepatitis with reversible liver fibrosis

scientific article published on 01 December 1981

A plan for a new health leader training course at Tokai University

scientific article published on 01 September 1995

Activation of two distinct MAPK pathways governs constitutive expression of matrix metalloproteinase-1 in human pancreatic cancer cell lines.

scientific article

Acute hepatitis in an adult with acquired rubella infection.

scientific article published on August 1995

Additional candidates to conventional genes susceptible for lung cancer and changing trend in Japan.

scientific article published on June 2010

Aldehyde dehydrogenase 2 and beta3-adrenergic receptor gene polymorphisms: their association with elevated liver enzymes and metabolic syndrome.

scientific article published in September 2003

All-trans retinoic acid down-regulates human albumin gene expression through the induction of C/EBPbeta-LIP

scientific article

Anal atresia: effect of smoking and drinking habits during pregnancy

scientific article published on 01 December 1995

Aortitis syndrome associated with ulcerative colitis.

scientific article

Associations between glycated hemoglobin levels and atherosclerotic risk factors in urban communities

scientific article published in August 2002

Bone marrow-derived cells express matrix metalloproteinases and contribute to regression of liver fibrosis in mice

scientific article published in January 2007

Budd-Chiari syndrome: relation of clinical features and angiographical findings (author's transl)

scientific article published on January 1, 1979

Capillarization of hepatic sinusoids in carbon tetrachloride-induced hepatic fibrosis

scientific article published on 01 January 1973

Cell type-specific intervention of transforming growth factor beta/Smad signaling suppresses collagen gene expression and hepatic fibrosis in mice

scientific article published in July 2005

Changes in serum levels of metalloproteinases and their inhibitors by treatment of chronic hepatitis C with interferon

scientific article published on 01 May 1996

Chylous Ascites Formation and a Review of 84 Cases ⬇️

scientific article published on October 1, 1973

Collagen biosynthesis in gastric cancer: immunohistochemical analysis of prolyl 4-hydroxylase

scientific article published on 01 April 1999

Collagenase activity in experimental hepatic fibrosis

scientific article published in Nature

Collagenase production by rabbit liver cells in monolayer culture

scientific article published on 01 October 1983

Detection of individual over-smoking using conventional laboratory tests

scientific article published on April 20, 2006

Difference in gene expression for matrix metalloproteinase-1 between early and advanced hepatocellular carcinomas

scientific article published on 01 March 1997

Different appearance of hepatic collagenase and lysosomal enzymes in recovery of experimental hepatic fibrosis

scientific article published on January 1, 1978

Direct measurement of neutral collagenase activity in homogenates from baboon and human liver

scientific article published on 01 March 1981

Dynamic change of cells expressing MMP-2 mRNA and MT1-MMP mRNA in the recovery from liver fibrosis in the rat

scientific article published on 01 October 2001

Effects of ethyl alcohol administration to THA rat dams during their gestation period on learning behavior and on levels of monoamines and metabolites in the brain of pups after birth.

scientific article

Effects of ethyl alcohol administration to rat dams during the gestation period on learning behavior and on levels of monoamines and metabolites in rat pup brain after birth.

scientific article published in July 1996

Elevation of laminin and beta-subunit of prolyl 4-hydroxylase in the sera of human subjects with Schistosomiasis mansoni

scientific article published on 01 June 1989

Emerging insights into Transforming growth factor beta Smad signal in hepatic fibrogenesis.

scientific article published on February 2007

Endogenous urinary 3-hydroxyproline has 96% specificity and 44% sensitivity for cancer screening

scientific article published on 01 December 1992

Expression of interstitial collagenase (matrix metalloproteinase-1) in gastric cancers.

scientific article

Fibrogenesis and Carcinogenesis in Nonalcoholic Steatohepatitis (NASH): Involvement of Matrix Metalloproteinases (MMPs) and Tissue Inhibitors of Metalloproteinase (TIMPs).

scientific article

Formation and degradation of basement membrane collagen

scientific article published on 01 January 1991

Gene expression of interstitial collagenase (matrix metalloproteinase 1) in gastrointestinal tract cancers

scientific article published on 01 August 1994

Gene expression of interstitial collagenase in both progressive and recovery phase of rat liver fibrosis induced by carbon tetrachloride

scientific article published on 01 August 2000

Genes associated with succeptibility to lung adenocarcinoma among never smokers suggest the mechanism of disease.

scientific article published on October 2014

Hepatic progenitor cell expansion in early-stage nonalcoholic steatohepatitis: evidence from immunohistochemistry and immunoelectron microscopy of matrix metalloproteinase-1

scientific article published on 02 June 2017

Hepatocyte growth factor suppresses profibrogenic signal transduction via nuclear export of Smad3 with galectin-7.

scientific article published on 11 January 2008

Inactive aldehyde dehydrogenase 2 worsens glycemic control in patients with type 2 diabetes mellitus who drink low to moderate amounts of alcohol

scientific article published on 01 April 2000

Interferon alfa down-regulates collagen gene transcription and suppresses experimental hepatic fibrosis in mice ⬇️

scientific article published on October 1, 2003

Introduction: MMPs, ADAMs/ADAMTSs research products to achieve big dream.

scientific article published on September 2012

Iron increases collagenase production by rabbit synovial fibroblasts.

scientific article

Lifestyle and colorectal cancer: A case-control study ⬇️

scientific article published on October 1, 1998

Lung Adenocarcinoma in Never Smokers: Problems of Primary Prevention from Aspects of Susceptible Genes and Carcinogens.

scientific article published on December 2016

Mammalian collagenase increases in early alcoholic liver disease and decreases with cirrhosis

scientific article published on 01 April 1982

Maternal drinking and smoking and the risk of birth defects

scientific article published in August 1994

Matrix metalloproteinase-13 promotes recovery from experimental liver cirrhosis in rats.

scientific article

Measurement of serum type III procollagen aminopeptide with RIA-gnost PIIIP coated tube: changes in patients with various alcoholic liver diseases after abstinence

scientific article published on February 1, 1992

Molecular mechanism of the reversibility of hepatic fibrosis: with special reference to the role of matrix metalloproteinases.

scientific article

Novel Cancer-targeting Agents/Application Strategies Developed from MMP Science

scientific article published on 31 January 2012

Novel breast cancer screening: combined expression of miR-21 and MMP-1 in urinary exosomes detects 95% of breast cancer without metastasis

scientific article published on 19 September 2019

Novel strategies for hepatocellular carcinoma based on MMPs science.

scientific article published on September 2012

Positive alpha-fetoprotein in a case of metastatic gastric carcinoma, Borrmann type 3

scientific article

Prolylhydroxylase and collagenase activities in the healing of acetic acid-induced gastric ulcers in rats and the effects of cimetidine and elcatonin

scientific article published on 01 January 1989

Radiographic and endoscopic features of colonic ulcers in systemic lupus erythematosus

scientific article published on October 1, 1975

Serum matrix metalloproteinase-1 level represents disease activity as opposed to fibrosis in patients with histologically proven nonalcoholic steatohepatitis.

scientific article published on 20 November 2017

Serum type III procollagen peptide in diagnosis of lung fibrosis due to silicosis and bleomycin toxicity

scientific article published on 01 September 1985

Serum type III procollagen peptide: indicator for pulmonary fibrosis. I. A tool for early detection of pulmonary fibrosis as a complication in cancer therapy

scientific article published on 01 June 1986

Serum type III procollagen peptide: indicator for pulmonary fibrosis: II. Application in 80 asbestos insulation workers

scientific article published on 01 January 1987

Significance of collagenase in digestive system diseases

scientific article published on January 1, 1976

Study on the fixation method of microcirculation system for electron microscopy

scientific article published on January 1, 1979

Ten year survival rate of 131 patients with liver cirrhosis excluded the association of liver carcinoma at the establishment of diagnosis

scientific article published on 01 January 1980

The use of docosahexaenoic acid supplementation to ameliorate the hyperactivity of rat pups induced by in utero ethanol exposure ⬇️

scientific article published on October 1, 2000

Treatment strategy for liver fibrosis through recruitment and differentiation of bone marrow stem/progenitor cells

scientific article published on 01 December 2007

Urinary concentrations of heavy metals in healthy Japanese under 20 years of age: a comparison between concentrations expressed in terms of creatinine and of selenium

scientific article published on 01 May 1995

Wound healing of acetic acid-induced gastric ulcer in rats and the effects of cimetidine and calcitonin, with special reference to prolylhydroxylase and collagenase enzyme activity

scientific article published on 01 June 1995

[A case with gold nephropathy: X-ray energy dispersive analysis of gold deposition in renal tissue (author's transl)]

scientific article published on 01 March 1982

[A survey of subjective symptoms and life-style in junior high school students]

scientific article published on 01 July 2006

[Advances in the treatment of jaundice in the department of internal medicine]

scientific article published on 01 September 1972

[Alteration of drinking pattern after the entrance of university]

scientific article published on 01 December 1995

[An epidemiological study of allergic conjunctivitis]

scientific article published on 01 February 1993

[Analysis of factors affecting breakfast skipping by male students undergoing hard training for sports]

scientific article published on 01 September 2002

[Application of serum type III procollagen peptide level in the diagnosis of lung fibrosis developed during bleomycin treatment in cancer patients]

scientific article published on 01 October 1985

[Clinical significance of procollagen peptide analysis in biochemical tests]

scientific article published on 01 December 1989

[Complication of therapeutic transcatheter hepatic artery embolization for hepatoma--case of developing an extensive acute gastric ulcer]

scientific article published on 01 February 1983

[Effects of aging on urinary secretion of 3-hydroxyproline and its importance for cancer screening in the elderly with ROC analysis]

scientific article published on 01 October 1994

[Epidemiological study on alcohol consumption and physical health in the Kitakyushu area with special reference to industrial structure]

scientific article published on 01 March 1986

[Gene expression of MMPs and TIMPs in the process of hepatic fibrosis]

scientific article published on 01 February 1993

[Hepatic damage in pancreatic diseases]

scientific article published on 01 December 1967

[Increased collagen catabolism in gastric mucosa of rats administered with hydrochloric acid solution, injected with gastrin, and restrained under stress]

scientific article published on 01 March 1984

[Mechanism of fibril of the liver--ultrastructure of acid mucopolysaccharides in collagen fiber formation and resorption]

scientific article published on 01 March 1974

[Recent advance in understanding mechanisms of fibrogenesis and fibrolysis in hepatic fibrosis]

scientific article published on 01 April 2002

[Report of the past 6 years' editing (2000-2005)]

scientific article published on 01 March 2006

[Review of neurobehavioral effects of alcohol-related neurodevelopmental disorder in an animal model]

scientific article published on 01 February 2006

[Serum type III procollagen peptide in diagnosis of lung fibrosis due to silicosis and bleomycin toxicity]

scientific article published on 01 March 1986

[Serum type III procollagen peptide in patients with pneumoconiosis]

scientific article published on 01 December 1983

c-Jun NH2-terminal kinase pathway is involved in constitutive matrix metalloproteinase-1 expression in a hepatocellular carcinoma-derived cell line.

scientific article published on May 2004

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