List of works - Peter Igarashi

A conserved Hox axis in the mouse and human female reproductive system: late establishment and persistent adult expression of the Hoxa cluster genes

scientific article published in December 1997

A minimal Ksp-cadherin promoter linked to a green fluorescent protein reporter gene exhibits tissue-specific expression in the developing kidney and genitourinary tract.

scientific article

A transcriptional network in polycystic kidney disease

scientific article

A unique variant of a homeobox gene related to Drosophila cut is expressed in mouse testis.

scientific article published in October 1996

Acute kidney injury and aberrant planar cell polarity induce cyst formation in mice lacking renal cilia.

scientific article

Advances in the pathogenesis and treatment of polycystic kidney disease

scientific article

Arginine-specific modification of rabbit muscle phosphoglucose isomerase: Differences in the inactivation by phenylglyoxal and butanedione and in the protection by substrate analogs

scientific article published on 01 March 1983

Autophagy plays a critical role in kidney tubule maintenance, aging and ischemia-reperfusion injury.

scientific article

CXCR4/CXCL12 hyperexpression plays a pivotal role in the pathogenesis of lupus.

scientific article

Cloning of cDNAs encoding a rabbit renal brush border membrane protein immunologically related to band 3. Sequence similarity with microsomal dipeptidase ⬇️

scientific article published on November 15, 1991

Cloning, sequence, and tissue distribution of a rabbit renal Na+/H+ exchanger transcript

scientific article

Collecting duct-specific Rh C glycoprotein deletion alters basal and acidosis-stimulated renal ammonia excretion

scientific article published on 25 March 2009

Covalent modification of the renal Na+/H+ exchanger by N,N'-dicyclohexylcarbodiimide.

scientific article

Cyst formation and activation of the extracellular regulated kinase pathway after kidney specific inactivation of Pkd1.

scientific article

Cystic renal neoplasia following conditional inactivation of apc in mouse renal tubular epithelium

scientific journal article

Epithelial-specific Cre/lox recombination in the developing kidney and genitourinary tract.

scientific article

Expression of a cut-related homeobox gene in developing and polycystic mouse kidney.

scientific article published in August 1996

Expression of the basolateral Na-K-Cl cotransporter during mouse nephrogenesis and embryonic development.

scientific article published on 30 June 2006

Filling the holes in cystic kidney disease research

scientific article

Following the expression of a kidney-specific gene from early development to adulthood

scientific article published on 01 January 2003

Generation and characterization of KsprtTA and KsptTA transgenic mice.

scientific article published on 28 March 2013

Genetics and pathogenesis of polycystic kidney disease.

scientific article

HNF-1beta regulates transcription of the PKD modifier gene Kif12

scientific article

Hematopoietic stem cells contribute to the regeneration of renal tubules after renal ischemia-reperfusion injury in mice.

scientific article published in May 2003

Hepatocyte nuclear factor 1β suppresses canonical Wnt signaling through transcriptional repression of lymphoid enhancer-binding factor 1

scientific article published on 13 October 2020

Hepatocyte nuclear factor-1β regulates Wnt signaling through genome-wide competition with β-catenin/lymphoid enhancer binding factor

scientific article published on 11 November 2019

Identification and purification of a renal amiloride-binding protein with properties of the Na+-H+ exchanger

scientific article published in Journal of Biological Chemistry

Immunocytochemical characterization of Na(+)-H+ exchanger isoform NHE-1 in rabbit kidney ⬇️

scientific article published on November 1, 1992

In utero diethylstilbestrol (DES) exposure alters Hox gene expression in the developing müllerian system.

scientific article

Increased hedgehog signaling in postnatal kidney results in aberrant activation of nephron developmental programs

scientific journal article

Inducible expression of kallikrein in renal tubular cells protects mice against spontaneous lupus nephritis

scientific article published in March 2013

Intragenic motifs regulate the transcriptional complexity of Pkhd1/PKHD1.

scientific article

Intrarenal cells, not bone marrow-derived cells, are the major source for regeneration in postischemic kidney

scientific article

Isolation and cDNA cloning of Ksp-cadherin, a novel kidney-specific member of the cadherin multigene family.

scientific article

Isolation of putative voltage-gated epithelial K-channel isoforms from rabbit kidney and LLC-PK1 cells ⬇️

scientific article published on January 1, 1992

Kidney-Specific Gene Targeting

article

Kidney-specific inactivation of Ofd1 leads to renal cystic disease associated with upregulation of the mTOR pathway

scientific article

Kidney-targeted Birt-Hogg-Dube gene inactivation in a mouse model: Erk1/2 and Akt-mTOR activation, cell hyperproliferation, and polycystic kidneys

scientific journal article

Ksp-cadherin gene promoter. II. Kidney-specific activity in transgenic mice.

scientific article published in October 1999

Localization of the renal Na?K?Cl cotransporter gene (Slc 12a1) on mouse Chromosome 2

article

Loss of Glis2/NPHP7 causes kidney epithelial cell senescence and suppresses cyst growth in the Kif3a mouse model of cystic kidney disease.

scientific article published on June 2016

Loss of NFAT5 results in renal atrophy and lack of tonicity-responsive gene expression

scientific article

Loss of cilia suppresses cyst growth in genetic models of autosomal dominant polycystic kidney disease

scientific article published on 28 July 2013

Loss of oriented cell division does not initiate cyst formation

scientific article

Mechanism of Fibrosis in -Related Autosomal Dominant Tubulointerstitial Kidney Disease

MicroRNAs regulate renal tubule maturation through modulation of Pkd1.

scientific article

Molecular biology of renal Na(+)-H+ exchangers.

scientific article

New insights into the role of HNF-1β in kidney (patho)physiology

scientific article published on 01 July 2018

Overview: nonmammalian organisms for studies of kidney development and disease.

scientific article

Planar cell polarity genes Celsr1 and Vangl2 are necessary for kidney growth, differentiation, and rostrocaudal patterning

scientific article published on 02 September 2016

Plasma hippurate in renal failure: high-performance liquid chromatography method and clinical application

scientific article published on 01 January 1987

Pod-1, a mesoderm-specific basic-helix-loop-helix protein expressed in mesenchymal and glomerular epithelial cells in the developing kidney

scientific journal article

Polycystic Kidney Disease

scientific article published on 11 April 2007

Preparation of 6-125I-labeled amiloride derivatives

scientific article published on 01 April 1988

Primary cilia regulate mTORC1 activity and cell size through Lkb1.

scientific article published on 24 October 2010

Proteolytic cleavage and nuclear translocation of fibrocystin is regulated by intracellular Ca2+ and activation of protein kinase C.

scientific article

Regulation of kidney-specific Ksp-cadherin gene promoter by hepatocyte nuclear factor-1beta

article

Renal and Bone Marrow Cells Fuse after Renal Ischemic Injury

scientific article published on 14 November 2007

Role of the hepatocyte nuclear factor-1beta (HNF-1beta) C-terminal domain in Pkhd1 (ARPKD) gene transcription and renal cystogenesis

scientific journal article

Searching for Stem/Progenitor Cells in the Adult Mouse Kidney

scientific article published on 01 December 2003

Smad2 protects against TGF-beta/Smad3-mediated renal fibrosis.

scientific article

Targeted inactivation of fh1 causes proliferative renal cyst development and activation of the hypoxia pathway

scientific journal article

The role for HNF-1beta-targeted collectrin in maintenance of primary cilia and cell polarity in collecting duct cells

scientific article

Tissue-specific regulation of the mouse Pkhd1 (ARPKD) gene promoter

scientific article

Transcription Factor Hepatocyte Nuclear Factor-1β (HNF-1β) Regulates MicroRNA-200 Expression through a Long Noncoding RNA

scientific article

Transcription Factor Hepatocyte Nuclear Factor-1β Regulates Renal Cholesterol Metabolism.

scientific article published on 28 December 2015

Transcription factors and apoptosis in kidney development.

scientific article published on May 1994

Uncompensated polyuria in a mouse model of Bartter's syndrome

scientific article

Wnt9b signaling regulates planar cell polarity and kidney tubule morphogenesis

scientific journal article

Zyxin regulates migration of renal epithelial cells through activation of hepatocyte nuclear factor-1β

scientific article published on 08 May 2013

cDNA cloning and chromosomal localization of the human and mouse isoforms of Ksp-cadherin

scientific article

cDNA cloning and immunolocalization of a Na(+)-H+ exchanger in LLC-PK1 renal epithelial cells ⬇️

scientific article published on December 1, 1991

cDNA cloning and localization of a band 3-related protein from ileum

scientific article published on September 1, 1992

microRNA-17 family promotes polycystic kidney disease progression through modulation of mitochondrial metabolism

scientific article published on 16 February 2017

List of works by Peter Igarashi

A conserved Hox axis in the mouse and human female reproductive system: late establishment and persistent adult expression of the Hoxa cluster genes

A minimal Ksp-cadherin promoter linked to a green fluorescent protein reporter gene exhibits tissue-specific expression in the developing kidney and genitourinary tract.

A transcriptional network in polycystic kidney disease

A unique variant of a homeobox gene related to Drosophila cut is expressed in mouse testis.

Acute kidney injury and aberrant planar cell polarity induce cyst formation in mice lacking renal cilia.

Advances in the pathogenesis and treatment of polycystic kidney disease

Arginine-specific modification of rabbit muscle phosphoglucose isomerase: Differences in the inactivation by phenylglyoxal and butanedione and in the protection by substrate analogs

Autophagy plays a critical role in kidney tubule maintenance, aging and ischemia-reperfusion injury.

CXCR4/CXCL12 hyperexpression plays a pivotal role in the pathogenesis of lupus.

Cloning of cDNAs encoding a rabbit renal brush border membrane protein immunologically related to band 3. Sequence similarity with microsomal dipeptidase ⬇️

Cloning, sequence, and tissue distribution of a rabbit renal Na+/H+ exchanger transcript

Collecting duct-specific Rh C glycoprotein deletion alters basal and acidosis-stimulated renal ammonia excretion

Covalent modification of the renal Na+/H+ exchanger by N,N'-dicyclohexylcarbodiimide.

Cyst formation and activation of the extracellular regulated kinase pathway after kidney specific inactivation of Pkd1.

Cystic renal neoplasia following conditional inactivation of apc in mouse renal tubular epithelium

Epithelial-specific Cre/lox recombination in the developing kidney and genitourinary tract.

Expression of a cut-related homeobox gene in developing and polycystic mouse kidney.

Expression of the basolateral Na-K-Cl cotransporter during mouse nephrogenesis and embryonic development.

Filling the holes in cystic kidney disease research

Following the expression of a kidney-specific gene from early development to adulthood

Generation and characterization of KsprtTA and KsptTA transgenic mice.

Genetics and pathogenesis of polycystic kidney disease.

HNF-1beta regulates transcription of the PKD modifier gene Kif12

Hematopoietic stem cells contribute to the regeneration of renal tubules after renal ischemia-reperfusion injury in mice.

Hepatocyte nuclear factor 1β suppresses canonical Wnt signaling through transcriptional repression of lymphoid enhancer-binding factor 1

Hepatocyte nuclear factor-1β regulates Wnt signaling through genome-wide competition with β-catenin/lymphoid enhancer binding factor

Identification and purification of a renal amiloride-binding protein with properties of the Na+-H+ exchanger

Immunocytochemical characterization of Na(+)-H+ exchanger isoform NHE-1 in rabbit kidney ⬇️

In utero diethylstilbestrol (DES) exposure alters Hox gene expression in the developing müllerian system.

Increased hedgehog signaling in postnatal kidney results in aberrant activation of nephron developmental programs

Inducible expression of kallikrein in renal tubular cells protects mice against spontaneous lupus nephritis

Intragenic motifs regulate the transcriptional complexity of Pkhd1/PKHD1.

Intrarenal cells, not bone marrow-derived cells, are the major source for regeneration in postischemic kidney

Isolation and cDNA cloning of Ksp-cadherin, a novel kidney-specific member of the cadherin multigene family.

Isolation of putative voltage-gated epithelial K-channel isoforms from rabbit kidney and LLC-PK1 cells ⬇️

Kidney-Specific Gene Targeting

Kidney-specific inactivation of Ofd1 leads to renal cystic disease associated with upregulation of the mTOR pathway

Kidney-targeted Birt-Hogg-Dube gene inactivation in a mouse model: Erk1/2 and Akt-mTOR activation, cell hyperproliferation, and polycystic kidneys

Ksp-cadherin gene promoter. II. Kidney-specific activity in transgenic mice.

Localization of the renal Na?K?Cl cotransporter gene (Slc 12a1) on mouse Chromosome 2

Loss of Glis2/NPHP7 causes kidney epithelial cell senescence and suppresses cyst growth in the Kif3a mouse model of cystic kidney disease.

Loss of NFAT5 results in renal atrophy and lack of tonicity-responsive gene expression

Loss of cilia suppresses cyst growth in genetic models of autosomal dominant polycystic kidney disease

Loss of oriented cell division does not initiate cyst formation

Mechanism of Fibrosis in -Related Autosomal Dominant Tubulointerstitial Kidney Disease

MicroRNAs regulate renal tubule maturation through modulation of Pkd1.

Molecular biology of renal Na(+)-H+ exchangers.

New insights into the role of HNF-1β in kidney (patho)physiology

Overview: nonmammalian organisms for studies of kidney development and disease.

Planar cell polarity genes Celsr1 and Vangl2 are necessary for kidney growth, differentiation, and rostrocaudal patterning

Plasma hippurate in renal failure: high-performance liquid chromatography method and clinical application

Pod-1, a mesoderm-specific basic-helix-loop-helix protein expressed in mesenchymal and glomerular epithelial cells in the developing kidney

Polycystic Kidney Disease

Preparation of 6-125I-labeled amiloride derivatives

Primary cilia regulate mTORC1 activity and cell size through Lkb1.

Proteolytic cleavage and nuclear translocation of fibrocystin is regulated by intracellular Ca2+ and activation of protein kinase C.

Regulation of kidney-specific Ksp-cadherin gene promoter by hepatocyte nuclear factor-1beta

Renal and Bone Marrow Cells Fuse after Renal Ischemic Injury

Role of the hepatocyte nuclear factor-1beta (HNF-1beta) C-terminal domain in Pkhd1 (ARPKD) gene transcription and renal cystogenesis

Searching for Stem/Progenitor Cells in the Adult Mouse Kidney

Smad2 protects against TGF-beta/Smad3-mediated renal fibrosis.

Targeted inactivation of fh1 causes proliferative renal cyst development and activation of the hypoxia pathway

The role for HNF-1beta-targeted collectrin in maintenance of primary cilia and cell polarity in collecting duct cells

Tissue-specific regulation of the mouse Pkhd1 (ARPKD) gene promoter

Transcription Factor Hepatocyte Nuclear Factor-1β (HNF-1β) Regulates MicroRNA-200 Expression through a Long Noncoding RNA

Transcription Factor Hepatocyte Nuclear Factor-1β Regulates Renal Cholesterol Metabolism.

Transcription factors and apoptosis in kidney development.

Uncompensated polyuria in a mouse model of Bartter's syndrome

Wnt9b signaling regulates planar cell polarity and kidney tubule morphogenesis

Zyxin regulates migration of renal epithelial cells through activation of hepatocyte nuclear factor-1β

cDNA cloning and chromosomal localization of the human and mouse isoforms of Ksp-cadherin

cDNA cloning and immunolocalization of a Na(+)-H+ exchanger in LLC-PK1 renal epithelial cells ⬇️

cDNA cloning and localization of a band 3-related protein from ileum

microRNA-17 family promotes polycystic kidney disease progression through modulation of mitochondrial metabolism