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List of works by Alexandre S. Boutorine

A new method for the determination of the relative affinity of a ligand against various DNA sequences by electrospray ionization mass spectrometry. Application to a polyamide minor groove binder.

scientific article

Application of Cu(I)-catalyzed azide-alkyne cycloaddition for the design and synthesis of sequence specific probes targeting double-stranded DNA.

scientific article

Binding Properties of the Conjugates of Oligo(2′‐O‐Methylribonucleotides) with Minor Groove Binders Targeted to Double Stranded DNA

scientific article published on 01 October 2004

Biophysical analysis of triple-helix formation

scientific article

Conjugates of Oligo(2′-O-Methylribonucleotides) with Minor Groove Binders as New Sequence-Specific Agents Recognizing Both Grooves of Double-Stranded DNA ⬇️

scientific article published on May 1, 2003

Design and Optimization of Camptothecin Conjugates of Triple Helix-forming Oligonucleotides for Sequence-specific DNA Cleavage by Topoisomerase I ⬇️

scientific article published on November 27, 2001

Design, synthesis and biological properties of fulleropyrrolidine derivatives as potential DNA photo-probes

Effect of derivatization of ribophosphate backbone and terminal ribophosphate groups in oligoribonucleotides on their stability and interaction with eukaryotic cells

scientific article published on 01 January 1994

Effect of the terminal phosphate derivatization of beta- and alpha-oligodeoxynucleotides on their antisense activity in protein biosynthesis, stability and uptake by eucaryotic cells

scientific article published on 01 May 1992

Fluorescence energy transfer as a probe for nucleic acid structures and sequences.

scientific article

Fluorescent probes for nucleic Acid visualization in fixed and live cells.

scientific article

Functionalized head-to-head hairpin polyamides: synthesis, double-stranded DNA-binding activity and affinity

scientific article published in August 2005

Micelles of lipid-oligonucleotide conjugates: implications for membrane anchoring and base pairing.

scientific article

Monitoring DNA triplex formation using multicolor fluorescence and application to insulin-like growth factor I promoter downregulation.

scientific article published on 27 January 2014

Oligonucleotide-minor groove binder conjugates and their complexes with complementary DNA: effect of conjugate structural factors on the thermal stability of duplexes.

scholarly article

Optimization of the sequence of twisted intercalating nucleic acids (TINA) forming triple helix with the polypurine tract of the proviral HIV DNA.

scientific article

Optimized synthesis and enhanced efficacy of novel triplex-forming camptothecin derivatives based on gimatecan

scientific article

Polyamide fluorescent probes for visualization of repeated DNA sequences in living cells.

scientific article published on 30 January 2015

Reversible covalent attachment of cholesterol to oligodeoxyribonucleotides for studies of the mechanisms of their penetration into eucaryotic cells.

scientific article

Sequence-specific DNA cleavage mediated by bipyridine polyamide conjugates.

scientific article published on May 2008

Sequence-specific conjugates of oligo(2'-O-methylribonucleotides) and hairpin oligocarboxamide minor-groove binders: design, synthesis, and binding studies with double-stranded DNA.

scientific article published on July 2005

Sequence-specific recognition of double-stranded DNA by synthetic minor groove binder conjugates. toward the construction of artificial site-specific deoxyribonucleases

scientific article

Spatial organization of topoisomerase I-mediated DNA cleavage induced by camptothecin-oligonucleotide conjugates.

scientific article

Stabilization of DNA Double and Triple Helices by Conjugation of Minor Groove Binders to Oligonucleotides ⬇️

scientific article published on May 1, 2003

Studies of sequence-specific recognition and interaction of bishairpin polyamide minor groove binders with target DNA duplexes.

scientific article

Synthesis of mouse centromere-targeted polyamides and physico-chemical studies of their interaction with the target double-stranded DNA.

scientific article published on 2 July 2015

Targeting of HIV gp120 by oligonucleotide-photosensitizer conjugates. Light-induced damages.

scientific article

Targeting topoisomerase I cleavage to specific sequences of DNA by triple helix-forming oligonucleotide conjugates. A comparison between a rebeccamycin derivative and camptothecin

scientific article published on 01 September 1999

Triple helix-forming oligonucleotides conjugated to indolocarbazole poisons direct topoisomerase I-mediated DNA cleavage to a specific site.

scientific article published in July 2001

Triplex‐Forming Twisted Intercalating Nucleic Acids (TINAs): Design Rules, Stabilization of Antiparallel DNA Triplexes and Inhibition of G‐Quartet‐Dependent Self‐Association ⬇️

scientific article published on October 17, 2011

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