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List of works by Dirk J Grünhagen

Abdominal Desmoid Tumors: Hands Off?

scientific article published on 08 March 2016

Activated Signaling Pathways and Targeted Therapies in Desmoid-Type Fibromatosis: A Literature Review.

scientific article published on 17 May 2019

Adjuvant Hepatic Arterial Infusion Pump Chemotherapy After Resection of Colorectal Liver Metastases: Results of a Safety and Feasibility Study in The Netherlands

scientific article published on 22 October 2019

Angiogenic desmoplastic histopathological growth pattern as a prognostic marker of good outcome in patients with colorectal liver metastases

scientific article published on 12 January 2019

B Cells as Prognostic Biomarker After Surgery for Colorectal Liver Metastases

scientific article published on 05 March 2020

Biliary reconstruction when the liver hilum is inaccessible: the anterior approach

scientific article published on 13 January 2012

Blockade of LAG3 enhances responses of tumor-infiltrating T cells in mismatch repair-proficient liver metastases of colorectal cancer.

scientific article published on 25 April 2018

Claudin-2 promotes colorectal cancer liver metastasis and is a biomarker of the replacement type growth pattern

scientific article published on 02 June 2021

Clinical characteristics and treatment outcome in a large multicentre observational cohort of PDGFRA exon 18 mutated gastrointestinal stromal tumour patients

scientific article published on 8 March 2017

Does portal vein embolization prior to liver resection influence the oncological outcomes - A propensity score matched comparison

scientific article published on 20 September 2017

Early Evaluation of Response Using 18F-FDG PET Influences Management in Gastrointestinal Stromal Tumor Patients Treated with Neoadjuvant Imatinib

scientific article published on 28 September 2017

Effects of time interval between primary melanoma excision and sentinel node biopsy on positivity rate and survival.

scientific article published on 23 September 2016

Efficacy of repeat isolated limb perfusions with tumor necrosis factor alpha and melphalan for multiple in-transit metastases in patients with prior isolated limb perfusion failure

scientific article published on 22 June 2005

Elderly patients with gastrointestinal stromal tumour (GIST) receive less treatment irrespective of performance score or comorbidity - A retrospective multicentre study in a large cohort of GIST patients.

scientific article

Erratum to: gamma probe and ultrasound guided fine needle aspiration cytology of the sentinel node (GULF) trial - overview of the literature, pilot and study protocol

scientific article published on 30 May 2017

Favorable overall survival in stage III melanoma patients after adjuvant dendritic cell vaccination.

scientific article published on 5 June 2015

GITR engagement in combination with CTLA-4 blockade completely abrogates immunosuppression mediated by human liver tumor-derived regulatory T cells ex vivo

scientific article

Gamma probe and ultrasound guided fine needle aspiration cytology of the sentinel node (GULF) trial - overview of the literature, pilot and study protocol.

scientific article

Gamma probe and ultrasound-guided fine needle aspiration cytology of the sentinel node (GULF) trial

scientific article published on 26 April 2018

Histopathological growth patterns and positive margins after resection of colorectal liver metastases

scientific article published on 14 November 2019

Histopathological growth patterns as biomarker for adjuvant systemic chemotherapy in patients with resected colorectal liver metastases

scientific article published on 20 July 2020

Identification and assessment of health-related quality of life issues in patients with sporadic desmoid-type fibromatosis: a literature review and focus group study

scientific article published on 16 July 2018

Implementation of the 7th edition AJCC staging system: Effects on staging and survival for pT1 melanoma. A Dutch population based study

scientific article published on 20 January 2017

Increasing Costs of Skin Cancer due to Increasing Incidence and Introduction of Pharmaceuticals, 2007-2017

scientific article published on 19 March 2020

Influence of margins on overall survival after hepatic resection for colorectal metastasis: a meta-analysis

scientific article published on 01 January 2015

International consensus guidelines for scoring the histopathological growth patterns of liver metastasis

scientific article

Isolated (hypoxic) hepatic perfusion with high-dose chemotherapy in patients with unresectable liver metastases of uveal melanoma: results from two experienced centres.

scientific article published on 10 August 2016

Isolated limb perfusion for melanoma patients--a review of its indications and the role of tumour necrosis factor-alpha.

scientific article

Isolated limb perfusion for unresectable extremity cutaneous squamous cell carcinoma; an effective limb saving strategy

scientific article published on 02 July 2018

Isolated limb perfusion using tumour necrosis factor α and melphalan in patients with advanced aggressive fibromatosis.

scientific article

Isolated limb perfusion with TNF-alpha and melphalan in locally advanced soft tissue sarcomas of the extremities.

scientific article

Isolated limb perfusion with melphalan and TNF-alpha in the treatment of extremity sarcoma

scientific article

Isolated limb perfusion with tumor necrosis factor and melphalan prevents amputation in patients with multiple sarcomas in arm or leg.

scientific article published on 19 April 2005

Isolated limb perfusions with tumor necrosis factor and melphalan for locally recurrent soft tissue sarcoma in previously irradiated limbs.

scientific article published on 31 March 2005

Laparoscopic-monitored colonoscopic polypectomy: a multimodality method to avoid segmental colon resection

scientific article published on 01 November 2011

Local excision of rectal cancer after chemoradiation: feasibility depends on the primary stage.

scientific article published on 9 March 2010

Long-term outcome of isolated limb perfusion with tumour necrosis factor-α for patients with melanoma in-transit metastases.

scientific article

Long-term results of the "liver first" approach in patients with locally advanced rectal cancer and synchronous liver metastases

scientific article

Metal stents: a bridge to surgery in hilar cholangiocarcinoma

scientific article published on 16 October 2012

Molecular characteristics of circulating tumor cells resemble the liver metastasis more closely than the primary tumor in metastatic colorectal cancer

scientific article published on 20 June 2016

Multicenter Observational Study of Adhesion Formation after Open-and Laparoscopic Surgery for Colorectal Cancer.

scientific article published on 15 February 2017

Neo-adjuvant chemotherapy followed by surgery versus surgery alone in high-risk patients with resectable colorectal liver metastases: the CHARISMA randomized multicenter clinical trial

scientific article

One hundred consecutive isolated limb perfusions with TNF-alpha and melphalan in melanoma patients with multiple in-transit metastases

scientific article published in December 2004

Outcome after surgical treatment of dermatofibrosarcoma protuberans: Is clinical follow-up always indicated?

scientific article published on 15 January 2019

Outcome and prognostic factor analysis of 217 consecutive isolated limb perfusions with tumor necrosis factor-alpha and melphalan for limb-threatening soft tissue sarcoma

scientific article published in April 2006

Outcome of Nonsurgical Management of Extra-Abdominal, Trunk, and Abdominal Wall Desmoid-Type Fibromatosis: A Population-Based Study in the Netherlands

scientific article published on 21 June 2018

Pathological features of vessel co-option versus sprouting angiogenesis

scientific article published on 26 October 2019

Perfusion and infusion for melanoma in-transit metastases in the era of effective systemic therapy.

scientific article published on January 2015

Posttreatment Surveillance in Patients with Prolonged Disease-Free Survival After Resection of Colorectal Liver Metastasis

scientific article published on 08 July 2016

Primary tumor location and the prognosis of patients after local treatment of colorectal liver metastases: a systematic review and meta-analysis

scientific article published on 24 October 2019

Prognostic factors after cervical lymph node dissection for cutaneous melanoma metastases

scientific article published in June 2005

Prognostic value of CTNNB1 gene mutation in primary sporadic aggressive fibromatosis

scientific article published on 24 October 2014

Prognostic value of circulating tumour cells for early recurrence after resection of colorectal liver metastases

scientific article published on 6 January 2015

Quality of treatment and surgical approach for rectal gastrointestinal stromal tumour (GIST) in a large European cohort

scientific article published on 06 March 2020

Recurrence Patterns After Resection of Colorectal Liver Metastasis are Modified by Perioperative Systemic Chemotherapy

scientific article published on 01 March 2020

Regional treatment of metastasis: role of regional perfusion. State of the art isolated limb perfusion for limb salvage

scientific article published in January 2004

Repeated isolated limb perfusion in melanoma patients with recurrent in-transit metastases

scientific article published on 23 June 2015

Reshaping the critical role of surgeons in oncology research

scientific article published on 01 May 2019

Risk Factors for Positive Deep Pelvic Nodal Involvement in Patients with Palpable Groin Melanoma Metastases: Can the Extent of Surgery be Safely Minimized? : A Retrospective, Multicenter Cohort Study.

scientific article

Risk stratification of sentinel node-positive melanoma patients defines surgical management and adjuvant therapy treatment considerations.

scientific article published on 13 April 2018

Safety and Feasibility of Additional Tumor Debulking to First-Line Palliative Combination Chemotherapy for Patients with Multiorgan Metastatic Colorectal Cancer

scientific article published on 03 June 2020

Salvage treatment for recurrences after first resection of colorectal liver metastases: the impact of histopathological growth patterns

Short term and long term results of patients with colorectal liver metastases undergoing surgery with or without radiofrequency ablation

scientific article published on 23 January 2016

Stereotactic body radiotherapy for oligometastatic soft tissue sarcoma

scientific article published on 19 June 2018

Surveillance after curative treatment for colorectal cancer

scientific article published on 20 December 2016

TNF dose reduction in isolated limb perfusion.

scientific article published on 15 August 2005

TNF-based isolated limb perfusion in unresectable extremity desmoid tumours

scientific article published in October 2005

TNF-based isolated limb perfusion: a decade of experience with antivascular therapy in the management of locally advanced extremity soft tissue sarcomas.

scientific article published in January 2004

Technology insight: Utility of TNF-alpha-based isolated limb perfusion to avoid amputation of irresectable tumors of the extremities

scientific article published in February 2006

The Disease-Free Interval Between Resection of Primary Colorectal Malignancy and the Detection of Hepatic Metastases Predicts Disease Recurrence But Not Overall Survival

scientific article published on 30 May 2019

The Prognostic Value of Post-operative Serum C-reactive Protein Level for -Survival after Surgery for Colorectal Liver Metastases.

scientific article published on September 2015

The history of adoption of hepatic resection for metastatic colorectal cancer: 1984-95.

scientific article

The impact of hepatic arterial infusion pump chemotherapy on hepatic recurrences and survival in patients with resected colorectal liver metastases

scientific article published on 27 December 2019

The palliative value of tumor necrosis factor alpha-based isolated limb perfusion in patients with metastatic sarcoma and melanoma

scientific article published in January 2006

The prognostic value of the primary tumor’s nodal status after surgery for colorectal liver metastases in the era of effective systemic therapy

scientific article

The use of neo-adjuvant chemotherapy in patients with resectable colorectal liver metastases: Clinical risk score as possible discriminator.

scientific article published on 2 May 2015

Time trends in the incidence and treatment of extra-abdominal and abdominal aggressive fibromatosis: a population-based study.

scientific article published on 5 June 2015

Transepidermal Water Loss During Halogen Spotlight Phototherapy in Preterm Infants

scientific article published on 01 March 2002

Treatment modifications in tumour necrosis factor-α (TNF)-based isolated limb perfusion in patients with advanced extremity soft tissue sarcomas.

scientific article published on 16 December 2014

Tumor-infiltrating plasmacytoid dendritic cells promote immunosuppression by Tr1 cells in human liver tumors.

scientific article published on 19 March 2015

Upregulation of intratumoral HLA class I and peritumoral Mx1 in ulcerated melanomas

scientific article published on 06 September 2019

Vismodegib for giant, locally advanced, basal cell carcinoma and its complex position in clinical practice

article published in 2019

Wnt targets genes are not differentially expressed in desmoid tumors bearing different activating β-catenin mutations

scientific article published on 18 October 2018

mRNA expression profiles of colorectal liver metastases as a novel biomarker for early recurrence after partial hepatectomy.

scientific article published on 20 September 2016

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