List of works - Mark R Wormald

3-Fluoroazetidinecarboxylic Acids and trans,trans-3,4-Difluoroproline as Peptide Scaffolds: Inhibition of Pancreatic Cancer Cell Growth by a Fluoroazetidine Iminosugar

scientific article published on 17 April 2015

6-Deoxyhexoses from l-Rhamnose in the Search for Inducers of the Rhamnose Operon: Synergy of Chemistry and Biotechnology.

scientific article

A nonself sugar mimic of the HIV glycan shield shows enhanced antigenicity

scientific article

Afamin is a novel human vitamin E-binding glycoprotein characterization and in vitro expression

scientific article

Antibody domain exchange is an immunological solution to carbohydrate cluster recognition

scientific article

At least two Fc Neu5Gc residues of monoclonal antibodies are required for binding to anti-Neu5Gc antibody

scientific article published on 29 January 2016

Cancer-associated glycoforms of gelatinase B exhibit a decreased level of binding to galectin-3.

scientific article published on 6 December 2006

Carbohydrates and glycoconjugates: progress in non-mammalian glycosylation, glycosyltransferases, invertebrate lectins and carbohydrate-carbohydrate interactions

scientific article published on 01 October 2004

Challenges of glycosylation analysis and control: an integrated approach to producing optimal and consistent therapeutic drugs

scientific article

Characterisation of oligosaccharides from Drosophila melanogaster glycoproteins

scientific article published in October 1991

Circulating Truncated Alpha-1 Antitrypsin Glycoprotein in Patient Plasma Retains Anti-Inflammatory Capacity

scientific article published on 22 February 2019

Complement regulation at the molecular level: The structure of decay-accelerating factor

scientific article

Comprehensive N-Glycan Profiling of Avian Immunoglobulin Y.

scientific article

Conformational studies of oligosaccharides and glycopeptides: complementarity of NMR, X-ray crystallography, and molecular modelling

scientific article

Crystal structures of two H-2Db/glycopeptide complexes suggest a molecular basis for CTL cross-reactivity

scientific article

Crystallographic, thermodynamic, and molecular modeling studies of the mode of binding of oligosaccharides to the potent antiviral protein griffithsin

scientific article

Design, synthesis, and biological evaluation of enantiomeric beta-N-acetylhexosaminidase inhibitors LABNAc and DABNAc as potential agents against Tay-Sachs and Sandhoff disease.

scientific article

Differential N-glycosylation of a monoclonal antibody expressed in tobacco leaves with and without endoplasmic reticulum retention signal apparently induces similar in vivo stability in mice

scientific article published on 07 August 2011

Eight stereoisomers of homonojirimycin from D-mannose

scientific article published on 03 April 2012

Fast sequencing of oligosaccharides: the reagent-array analysis method ⬇️

scientific article published on July 15, 1992

Fc gamma receptors: glycobiology and therapeutic prospects

scientific article

Glycosylation and Fc receptors

scientific article published on January 2014

Glycosylation and prion protein.

scientific article

Glycosylation changes of IgG associated with rheumatoid arthritis can activate complement via the mannose-binding protein

scientific article published on 01 March 1995

Glycosylation changes on serum glycoproteins in ovarian cancer may contribute to disease pathogenesis.

scientific article published on January 2008

Glycosylation influences the lectin activities of the macrophage mannose receptor

scientific article

Glycosylation of natural human neutrophil gelatinase B and neutrophil gelatinase B-associated lipocalin.

scientific article

High throughput isolation and glycosylation analysis of IgG-variability and heritability of the IgG glycome in three isolated human populations

scientific article

Human follicular lymphoma cells contain oligomannose glycans in the antigen-binding site of the B-cell receptor.

scientific article published on 29 December 2006

Human serum IgM glycosylation: identification of glycoforms that can bind to mannan-binding lectin

scientific article published on 14 June 2005

Identification and description of beta-structure in horse muscle acylphosphatase by nuclear magnetic resonance spectroscopy

scientific article published on 01 May 1989

Inhibition of mammalian glycan biosynthesis produces non-self antigens for a broadly neutralising, HIV-1 specific antibody

scientific article published on 16 June 2007

L-fucose from vitamin C with only acetonide protection

scientific article published on 13 October 2014

Looking glass inhibitors: L-DMDP, a more potent and specific inhibitor of alpha-glucosidases than the enantiomeric natural product DMDP.

scientific article published on 29 July 2004

Mapping space by NMR using susceptibility changes at phase boundaries

scientific article published on 01 October 1986

Matrix remodelling enzymes, the protease cascade and glycosylation ⬇️

scientific article published on October 3, 2001

Modeling of the N-glycosylated transferrin receptor suggests how transferrin binding can occur within the surface coat of Trypanosoma brucei.

scientific article

Mutations at CriticalN-Glycosylation Sites Reduce Tyrosinase Activity by Altering Folding and Quality Control

scientific article published on 01 March 2000

N-linked glycan structures of the human Fcγ receptors produced in NS0 cells.

scientific article published on 11 July 2013

New methods for measurement of long-range proton-carbon coupling constants in oligosaccharides

Nine of 16 stereoisomeric polyhydroxylated proline amides are potent β-N-acetylhexosaminidase inhibitors

scientific article published on 07 April 2014

O-Glycan Analysis of Natural Human Neutrophil Gelatinase B Using a Combination of Normal Phase- HPLC and Online Tandem Mass Spectrometry: Implications for the Domain Organization of the Enzyme†

article

O-glycan sialylation and the structure of the stalk-like region of the T cell co-receptor CD8.

scientific article

P12-06. A 'non-self' mimic of the natural epitope of anti-HIV antibody 2G12 shows enhanced antigenicity

article

P19-03. Molecular mechanisms for enhancing the antigenicity of the carbohydrate epitope of the broadly neutralizing anti-HIV-1 antibody 2G12.

scientific article published on 22 October 2009

Polyhydroxylated pyrrolidine and pyrrolizidine alkaloids from Hyancinthoides non-scripta and Scilla campanulata

scientific article published on 01 March 1999

Polysaccharide mimicry of the epitope of the broadly neutralizing anti-HIV antibody, 2G12, induces enhanced antibody responses to self oligomannose glycans

scientific article published on 24 February 2010

Remnant epitopes, autoimmunity and glycosylation.

scientific article

Secretory IgA N- and O-glycans provide a link between the innate and adaptive immune systems

scientific article published on 10 March 2003

Short communication: selective placental transport of maternal IgG to the fetus

scientific article published on 01 December 1995

Sialylation of urinary prothrombin fragment 1 is implicated as a contributory factor in the risk of calcium oxalate kidney stone formation

scientific article published on 01 July 2006

Soluble human TLR2 ectodomain binds diacylglycerol from microbial lipopeptides and glycolipids

scientific article published on 03 March 2014

Solution NMR studies of colicin E1 C-terminal thermolytic peptide. Structural comparison with colicin A and the effects of pH changes.

scientific article

Some structural features of the iron-uptake regulation protein ⬇️

scientific article published on April 10, 1991

Statistical analysis of the protein environment of N-glycosylation sites: implications for occupancy, structure, and folding.

scientific article published on 26 September 2003

Structural comparison of differently glycosylated forms of acid-β-glucosidase, the defective enzyme in Gaucher disease

scientific article published on 23 November 2006

Structure and function of X-Pro dipeptide repeats in the TonB proteins of Salmonella typhimurium and Escherichia coli.

scientific article published in December 1990

Sugar-mediated ligand-receptor interactions in the immune system

scientific article published in October 2004

Synthesis and solution-phase conformation of the RG-I fragment of the plant polysaccharide pectin reveals a modification-modulated assembly mechanism.

scientific article published in June 2010

Synthesis from D-altrose of (5R,6R,7R,8S)-5,7-dihydroxy-8-hydroxymethylconidine and 2,4-dideoxy-2,4-imino-D-glucitol, azetidine analogues of swainsonine and 1,4-dideoxy-1,4-imino-D-mannitol

scientific article published on 27 July 2012

Synthesis of fluorescence-labelled disaccharide substrates of glucosidase II.

scientific article published in September 2003

Synthetic Chemical Inducers and Genetic Decoupling Enable Orthogonal Control of the rhaBAD Promoter.

scientific article published on 31 May 2016

The BLT1 Inhibitory Function of α-1 Antitrypsin Augmentation Therapy Disrupts Leukotriene B4 Neutrophil Signaling

scientific article published on 14 September 2015

The Presence of Outer Arm Fucose Residues on theN-Glycans of Tissue Inhibitor of Metalloproteinases-1 Reduces Its Activity ⬇️

scientific article published on August 2, 2013

The Role and Importance of Glycosylation of Acute Phase Proteins with Focus on Alpha-1 Antitrypsin in Acute and Chronic Inflammatory Conditions

scientific article (publication date: 3 July 2014)

The conformational properties of the Glc3Man unit suggest conformational biasing within the chaperone-assisted glycoprotein folding pathway

scientific article

The effects of variable glycosylation on the functional activities of ribonuclease, plasminogen and tissue plasminogen activator.

scientific article published on April 1995

The hemopexin and O-glycosylated domains tune gelatinase B/MMP-9 bioavailability via inhibition and binding to cargo receptors

scientific article

The impact of glycosylation on the biological function and structure of human immunoglobulins.

scientific article published on January 2007

The importance of including local correlation times in the calculation of inter-proton distances from NMR measurements: ignoring local correlation times leads to significant errors in the conformational analysis of the Glcα1–2Glcα linkage by NMR

scientific article published in 2006

The solution NMR structure of glucosylated N-glycans involved in the early stages of glycoprotein biosynthesis and folding.

scientific article published on July 1997

The solution conformation of the Le chi group.

scientific article

The systematic use of negative nuclear Overhauser constraints in the determination of oligosaccharide conformations: application to sialyl-Lewis X

scientific article published on 01 August 1993

Triacetonide of Glucoheptonic Acid in the Scalable Syntheses of d-Gulose, 6-Deoxy-d-gulose, l-Glucose, 6-Deoxy-l-glucose, and Related Sugars.

scientific article published on 3 August 2016

Tyrosinase Folding and Copper Loading in Vivo: A Crucial Role for Calnexin and α-Glucosidase II

scientific article published on 01 August 1999

Variable region heavy chain glycosylation determines the anticoagulant activity of a factor VIII antibody.

scientific article published on May 2006

List of works by Mark R Wormald

3-Fluoroazetidinecarboxylic Acids and trans,trans-3,4-Difluoroproline as Peptide Scaffolds: Inhibition of Pancreatic Cancer Cell Growth by a Fluoroazetidine Iminosugar

6-Deoxyhexoses from l-Rhamnose in the Search for Inducers of the Rhamnose Operon: Synergy of Chemistry and Biotechnology.

A nonself sugar mimic of the HIV glycan shield shows enhanced antigenicity

Afamin is a novel human vitamin E-binding glycoprotein characterization and in vitro expression

Antibody domain exchange is an immunological solution to carbohydrate cluster recognition

At least two Fc Neu5Gc residues of monoclonal antibodies are required for binding to anti-Neu5Gc antibody

Cancer-associated glycoforms of gelatinase B exhibit a decreased level of binding to galectin-3.

Carbohydrates and glycoconjugates: progress in non-mammalian glycosylation, glycosyltransferases, invertebrate lectins and carbohydrate-carbohydrate interactions

Challenges of glycosylation analysis and control: an integrated approach to producing optimal and consistent therapeutic drugs

Characterisation of oligosaccharides from Drosophila melanogaster glycoproteins

Circulating Truncated Alpha-1 Antitrypsin Glycoprotein in Patient Plasma Retains Anti-Inflammatory Capacity

Complement regulation at the molecular level: The structure of decay-accelerating factor

Comprehensive N-Glycan Profiling of Avian Immunoglobulin Y.

Conformational studies of oligosaccharides and glycopeptides: complementarity of NMR, X-ray crystallography, and molecular modelling

Crystal structures of two H-2Db/glycopeptide complexes suggest a molecular basis for CTL cross-reactivity

Crystallographic, thermodynamic, and molecular modeling studies of the mode of binding of oligosaccharides to the potent antiviral protein griffithsin

Design, synthesis, and biological evaluation of enantiomeric beta-N-acetylhexosaminidase inhibitors LABNAc and DABNAc as potential agents against Tay-Sachs and Sandhoff disease.

Differential N-glycosylation of a monoclonal antibody expressed in tobacco leaves with and without endoplasmic reticulum retention signal apparently induces similar in vivo stability in mice

Eight stereoisomers of homonojirimycin from D-mannose

Fast sequencing of oligosaccharides: the reagent-array analysis method ⬇️

Fc gamma receptors: glycobiology and therapeutic prospects

Glycosylation and Fc receptors

Glycosylation and prion protein.

Glycosylation changes of IgG associated with rheumatoid arthritis can activate complement via the mannose-binding protein

Glycosylation changes on serum glycoproteins in ovarian cancer may contribute to disease pathogenesis.

Glycosylation influences the lectin activities of the macrophage mannose receptor

Glycosylation of natural human neutrophil gelatinase B and neutrophil gelatinase B-associated lipocalin.

High throughput isolation and glycosylation analysis of IgG-variability and heritability of the IgG glycome in three isolated human populations

Human follicular lymphoma cells contain oligomannose glycans in the antigen-binding site of the B-cell receptor.

Human serum IgM glycosylation: identification of glycoforms that can bind to mannan-binding lectin

Identification and description of beta-structure in horse muscle acylphosphatase by nuclear magnetic resonance spectroscopy

Inhibition of mammalian glycan biosynthesis produces non-self antigens for a broadly neutralising, HIV-1 specific antibody

L-fucose from vitamin C with only acetonide protection

Looking glass inhibitors: L-DMDP, a more potent and specific inhibitor of alpha-glucosidases than the enantiomeric natural product DMDP.

Mapping space by NMR using susceptibility changes at phase boundaries

Matrix remodelling enzymes, the protease cascade and glycosylation ⬇️

Modeling of the N-glycosylated transferrin receptor suggests how transferrin binding can occur within the surface coat of Trypanosoma brucei.

Mutations at CriticalN-Glycosylation Sites Reduce Tyrosinase Activity by Altering Folding and Quality Control

N-linked glycan structures of the human Fcγ receptors produced in NS0 cells.

New methods for measurement of long-range proton-carbon coupling constants in oligosaccharides

Nine of 16 stereoisomeric polyhydroxylated proline amides are potent β-N-acetylhexosaminidase inhibitors

O-Glycan Analysis of Natural Human Neutrophil Gelatinase B Using a Combination of Normal Phase- HPLC and Online Tandem Mass Spectrometry: Implications for the Domain Organization of the Enzyme†

O-glycan sialylation and the structure of the stalk-like region of the T cell co-receptor CD8.

P12-06. A 'non-self' mimic of the natural epitope of anti-HIV antibody 2G12 shows enhanced antigenicity

P19-03. Molecular mechanisms for enhancing the antigenicity of the carbohydrate epitope of the broadly neutralizing anti-HIV-1 antibody 2G12.

Polyhydroxylated pyrrolidine and pyrrolizidine alkaloids from Hyancinthoides non-scripta and Scilla campanulata

Polysaccharide mimicry of the epitope of the broadly neutralizing anti-HIV antibody, 2G12, induces enhanced antibody responses to self oligomannose glycans

Remnant epitopes, autoimmunity and glycosylation.

Secretory IgA N- and O-glycans provide a link between the innate and adaptive immune systems

Short communication: selective placental transport of maternal IgG to the fetus

Sialylation of urinary prothrombin fragment 1 is implicated as a contributory factor in the risk of calcium oxalate kidney stone formation

Soluble human TLR2 ectodomain binds diacylglycerol from microbial lipopeptides and glycolipids

Solution NMR studies of colicin E1 C-terminal thermolytic peptide. Structural comparison with colicin A and the effects of pH changes.

Some structural features of the iron-uptake regulation protein ⬇️

Statistical analysis of the protein environment of N-glycosylation sites: implications for occupancy, structure, and folding.

Structural comparison of differently glycosylated forms of acid-β-glucosidase, the defective enzyme in Gaucher disease

Structure and function of X-Pro dipeptide repeats in the TonB proteins of Salmonella typhimurium and Escherichia coli.

Sugar-mediated ligand-receptor interactions in the immune system

Synthesis and solution-phase conformation of the RG-I fragment of the plant polysaccharide pectin reveals a modification-modulated assembly mechanism.

Synthesis from D-altrose of (5R,6R,7R,8S)-5,7-dihydroxy-8-hydroxymethylconidine and 2,4-dideoxy-2,4-imino-D-glucitol, azetidine analogues of swainsonine and 1,4-dideoxy-1,4-imino-D-mannitol

Synthesis of fluorescence-labelled disaccharide substrates of glucosidase II.

Synthetic Chemical Inducers and Genetic Decoupling Enable Orthogonal Control of the rhaBAD Promoter.

The BLT1 Inhibitory Function of α-1 Antitrypsin Augmentation Therapy Disrupts Leukotriene B4 Neutrophil Signaling

The Presence of Outer Arm Fucose Residues on theN-Glycans of Tissue Inhibitor of Metalloproteinases-1 Reduces Its Activity ⬇️

The Role and Importance of Glycosylation of Acute Phase Proteins with Focus on Alpha-1 Antitrypsin in Acute and Chronic Inflammatory Conditions

The conformational properties of the Glc3Man unit suggest conformational biasing within the chaperone-assisted glycoprotein folding pathway

The effects of variable glycosylation on the functional activities of ribonuclease, plasminogen and tissue plasminogen activator.

The hemopexin and O-glycosylated domains tune gelatinase B/MMP-9 bioavailability via inhibition and binding to cargo receptors

The impact of glycosylation on the biological function and structure of human immunoglobulins.

The importance of including local correlation times in the calculation of inter-proton distances from NMR measurements: ignoring local correlation times leads to significant errors in the conformational analysis of the Glcα1–2Glcα linkage by NMR

The solution NMR structure of glucosylated N-glycans involved in the early stages of glycoprotein biosynthesis and folding.

The solution conformation of the Le chi group.

The systematic use of negative nuclear Overhauser constraints in the determination of oligosaccharide conformations: application to sialyl-Lewis X

Triacetonide of Glucoheptonic Acid in the Scalable Syntheses of d-Gulose, 6-Deoxy-d-gulose, l-Glucose, 6-Deoxy-l-glucose, and Related Sugars.

Tyrosinase Folding and Copper Loading in Vivo: A Crucial Role for Calnexin and α-Glucosidase II

Variable region heavy chain glycosylation determines the anticoagulant activity of a factor VIII antibody.