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List of works by Ayikoe G Mensah-Nyagan

A proposed preventive role for Gamma-hydroxybutyrate (Xyrem(R)) in Alzheimer's disease.

scientific article published on 06 September 2016

Allopregnanolone and Progesterone in Experimental Neuropathic Pain: Former and New Insights with a Translational Perspective

scientific article published on 05 September 2018

Allopregnanolone and its analog BR 297 rescue neuronal cells from oxidative stress-induced death through bioenergetic improvement.

scientific article

Allopregnanolone prevents and suppresses oxaliplatin-evoked painful neuropathy: multi-parametric assessment and direct evidence.

scientific article

Alzheimer's disease, oestrogen and mitochondria: an ambiguous relationship

scientific article

Alzheimer, mitochondria and gender

scientific article published on 29 April 2016

Anatomical and biochemical evidence for the synthesis of unconjugated and sulfated neurosteroids in amphibians

article

Anatomical and cellular localization of neuroactive 5 alpha/3 alpha-reduced steroid-synthesizing enzymes in the spinal cord

scientific journal article

Behavioral and electromyographic assessment of oxaliplatin-induced motor dysfunctions: Evidence for a therapeutic effect of allopregnanolone.

scientific article published on 24 October 2016

Behavioral, Electrophysiological, and Histological Characterization of a New Rat Model for Neoadjuvant Chemotherapy-Induced Neuropathic Pain: Therapeutic Potential of Duloxetine and Allopregnanolone Concomitant Treatment

scientific article published on 27 February 2020

Beneficial effects of Gelsemium-based treatment against paclitaxel-induced painful symptoms

scientific article published on 24 September 2018

Biochemical and functional evidence for the control of pain mechanisms by dehydroepiandrosterone endogenously synthesized in the spinal cord.

scientific article

Calcium and cAMP signaling induced by gamma-hydroxybutyrate receptor(s) stimulation in NCB-20 neurons.

scientific article

Cellular and functional evidence for a protective action of neurosteroids against vincristine chemotherapy-induced painful neuropathy.

scientific article

Characterization of a new rat model for chronic inflammatory demyelinating polyneuropathies

scientific article published on 27 November 2014

Detecting spatial memory deficits beyond blindness in tg2576 Alzheimer mice

scientific article published on 20 July 2012

Dose-dependent and sequence-sensitive effects of amyloid-beta peptide on neurosteroidogenesis in human neuroblastoma cells

scientific article

Endogenous steroid production in the spinal cord and potential involvement in neuropathic pain modulation.

scientific article published on 06 March 2008

Evidence for a key role of steroids in the modulation of pain.

scientific article published on December 2009

Evidence for effective structure-based neuromodulatory effects of new analogs of neurosteroid allopregnanolone

scientific article published on 19 December 2017

Gamma-hydroxybutyrate, acting through an anti-apoptotic mechanism, protects native and amyloid-precursor-protein-transfected neuroblastoma cells against oxidative stress-induced death.

scientific article published on 20 January 2014

HS3ST2 expression is critical for the abnormal phosphorylation of tau in Alzheimer's disease-related tau pathology.

scientific article published on 4 April 2015

Immunohistochemical localization of 3 beta-hydroxysteroid dehydrogenase and 5 alpha-reductase in the brain of the African lungfish Protopterus annectens.

scientific article

Impact of neuropathic pain on the gene expression and activity of cytochrome P450side-chain-cleavage in sensory neural networks.

scientific article published in September 2004

Improvement of neuronal bioenergetics by neurosteroids: implications for age-related neurodegenerative disorders

scientific article published on 2 October 2014

In vivo evidence for the production of sulfated steroids in the frog brain

scientific article published on 01 June 2000

Inflammatory Pain Upregulates Spinal Inhibition via Endogenous Neurosteroid Production

article

Inhibition of the mitochondrial enzyme ABAD restores the amyloid-β-mediated deregulation of estradiol

scientific article

Local modulation of steroid action: rapid control of enzymatic activity.

scientific article

Localization of 17beta-hydroxysteroid dehydrogenase and characterization of testosterone in the brain of the male frog

scientific article published on February 1996

Mechanisms for the Specific Properties of γ-Hydroxybutyrate in Brain

scientific article

Milestones on Steroids and the Nervous System: 10 years of basic and translational research.

scientific article

Modulation of neurosteroid production in human neuroblastoma cells by Alzheimer's disease key proteins

scientific article

Neonatal ventral hippocampal lesions modify pain perception and evoked potentials in rats

scientific article published on July 3, 2012

Neuroactive steroids: state of the art and new perspectives.

scientific article published on March 2008

Neurophysiological responses to unpleasant stimuli (acute electrical stimulations and emotional pictures) are increased in patients with schizophrenia

scientific article published on 3 March 2016

Neuroprotective Effects of Neuroactive Steroids in the Spinal Cord and Peripheral Nerves

scientific article published on 01 January 2006

Neurosteroid 3α-androstanediol efficiently counteracts paclitaxel-induced peripheral neuropathy and painful symptoms

scientific article

Neurosteroids and neuropathic pain management: Basic evidence and therapeutic perspectives

scientific article published on 25 September 2019

Neurosteroids: measurement and pathophysiologic relevance.

scientific article published on 26 September 2007

Novel analogs of allopregnanolone show improved efficiency and specificity in neuroprotection and stimulation of proliferation

scientific article published on 3 June 2016

Regulation of neurosteroid allopregnanolone biosynthesis in the rat spinal cord by glycine and the alkaloidal analogs strychnine and gelsemine.

scientific article

Regulation of neurosteroid biosynthesis in the frog diencephalon by GABA and endozepines.

scientific article

Sciatic nerve injury induces apoptosis of dorsal root ganglion satellite glial cells and selectively modifies neurosteroidogenesis in sensory neurons

scientific journal article

Selective regulation of 3 alpha-hydroxysteroid oxido-reductase expression in dorsal root ganglion neurons: a possible mechanism to cope with peripheral nerve injury-induced chronic pain

scientific article

Serum-based differentiation between multiple sclerosis and amyotrophic lateral sclerosis by Random Forest classification of FTIR spectra

scientific article published on 01 July 2019

Sex hormone-related neurosteroids differentially rescue bioenergetic deficits induced by amyloid-β or hyperphosphorylated tau protein

scientific article

Steroids, spinal cord and pain sensation.

scientific article

Substance P inhibits progesterone conversion to neuroactive metabolites in spinal sensory circuit: a potential component of nociception

scientific article published on 10 June 2005

The biological activity of 3alpha-hydroxysteroid oxido-reductase in the spinal cord regulates thermal and mechanical pain thresholds after sciatic nerve injury

scientific article

The octadecaneuropeptide ODN stimulates neurosteroid biosynthesis through activation of central-type benzodiazepine receptors.

scientific article

The small GTPase RhoA regulates the expression and function of the sodium channel Nav1.5 in breast cancer cells.

scientific article

Tryptophan metabolites modify brain Aβ peptide degradation: A role in Alzheimer's disease?

scientific article published on 29 April 2020

Xanthurenic acid binds to neuronal G-protein-coupled receptors that secondarily activate cationic channels in the cell line NCB-20

scientific article

Xanthurenic acid is localized in neurons in the central nervous system

scientific article published on 7 May 2016

γ-Hydroxybutyrate (Xyrem) ameliorates clinical symptoms and neuropathology in a mouse model of Alzheimer's disease

scientific article published on 13 October 2014