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List of works by Rachel E Simmonds

Coagulation, inflammation, and apoptosis: different roles for protein S and the protein S-C4b binding protein complex.

scientific article

Deletion or replacement of the second EGF-like domain of protein S results in loss of APC cofactor activity.

scientific article published on 10 October 2002

Efficient isolation of peptide ligands for the endothelial cell protein C receptor (EPCR) using candidate receptor phage display biopanning

scientific article published on 19 February 2005

Inhibition of Sec61-dependent translocation by mycolactone uncouples the integrated stress response from ER stress, driving cytotoxicity via translational activation of ATF4.

scientific article

Mechanistic insights into the inhibition of Sec61-dependent co- and post-translational translocation by mycolactone.

scientific article published on 11 February 2016

Molecular diversity and thrombotic risk in protein S deficiency: the PROSIT study.

scientific article published in March 2005

Mycolactone inhibits monocyte cytokine production by a posttranscriptional mechanism.

scientific article published in February 2009

Mycolactone reveals the substrate-driven complexity of Sec61-dependent transmembrane protein biogenesis.

scientific article published on 20 February 2017

Mycolactone-Dependent Depletion of Endothelial Cell Thrombomodulin Is Strongly Associated with Fibrin Deposition in Buruli Ulcer Lesions

scientific article (publication date: July 2015)

Pleiotropic molecular effects of the Mycobacterium ulcerans virulence factor mycolactone underlying the cell death and immunosuppression seen in Buruli ulcer

scientific article published on February 2014

Recent advances: role of mycolactone in the pathogenesis and monitoring of Mycobacterium ulcerans infection/Buruli ulcer disease.

scientific article

Signalling, inflammation and arthritis: NF-kappaB and its relevance to arthritis and inflammation.

scientific article published on 29 January 2008

TLR Signalling and Adapter Utilization in Primary Human In vitro Differentiated Adipocytes ⬇️

scientific article published on October 1, 2012

The pathogenic mechanism of the Mycobacterium ulcerans virulence factor, mycolactone, depends on blockade of protein translocation into the ER

scientific article (publication date: April 2014)

Transient up-regulation of miR-155-3p by lipopolysaccharide in primary human monocyte-derived macrophages results in RISC incorporation but does not alter TNF expression

scientific article published on 03 October 2019

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